Chest Medicine
ATS Research Statement | Causes, consequences, and treatments of sleep and circadian disruption in the ICU
3 May, 2023 | 15:18h | UTC
Commentary on Twitter
Causes, Consequences, and Treatments of Sleep and Circadian Disruption in the ICU: An Official American Thoracic Society Research Statement
🔓 Open Access
🔗 https://t.co/AKHd84D6Ry pic.twitter.com/U4bSRaC5uG— ATS Blue Journal (@ATSBlueEditor) April 13, 2023
Brief Review | Personalized noninvasive respiratory support for acute hypoxemic respiratory failure
3 May, 2023 | 15:00h | UTCPersonalized noninvasive respiratory support for acute hypoxemic respiratory failure – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Personalized noninvasive respiratory support for acute hypoxemic respiratory failure:
🫁 physiological rationale
🫁 clinical evidence
🫁 physiologically based patient‑targeted strategies
🫁 identification of treatment failure#FOAMcc on @yourICM
🖇️ https://t.co/O7cl2ShWzP pic.twitter.com/NCqo49ERv9— Intensive Care Medicine (@yourICM) April 29, 2023
RCT | Lung volume reduction surgery vs. endobronchial valves in patients with emphysema
2 May, 2023 | 13:29h | UTC
Commentary on Twitter
ERJ: In this first randomised study to compare lung volume reduction surgery and endobronchial valve placement in people who are suitable for both treatments, surgery did not produce substantially superior outcomes at 1 year post-procedure https://t.co/cFIVZijSJg pic.twitter.com/ZqRCgxYwLS
— ERS publications (@ERSpublications) May 1, 2023
RCT | Ventilation approaches in one-lung ventilation and pulmonary complications after major lung resection surgery
2 May, 2023 | 13:23h | UTC
Commentary on Twitter
One of the largest #RCTs on the management of one lung ventilation in #thoracicanesthesia (880 pts). https://t.co/ZVhTP5sv4o pic.twitter.com/KyLu4BE2yd
— Journal of Cardiothoracic and Vascular Anesthesia (@JCVAonline) April 30, 2023
Global burden of chronic respiratory diseases and risk factors, 1990–2019
28 Apr, 2023 | 13:17h | UTCNews Release: Chronic respiratory disease is third leading cause of death globally with air pollution killing 1.3 million people – IHME
Commentary on Twitter (thread – click for more)
Modifiable risk factors like air pollution were responsible for roughly 70% of chronic respiratory disease (#CRD) deaths, finds new global burden of disease study published in @eClinicalMed @TheLancet 🧵
»https://t.co/uUVZFdNWVV pic.twitter.com/kgMXOePlfS
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) April 25, 2023
CHEST/AARC/ATS/CTS Research Statement | Effect of race and ethnicity on pulmonary function testing interpretation
28 Apr, 2023 | 13:10h | UTCCommentary: Pulmonary Testing Based on Race, Ethnicity Found Flawed – Medscape (free registration required)
RCT | Albuterol–budesonide pressurized metered dose inhaler in patients with mild-to-moderate asthma
28 Apr, 2023 | 13:13h | UTCRelated study: Albuterol–Budesonide Fixed-Dose Combination Rescue Inhaler for Asthma – New England Journal of Medicine
M-A | Corticosteroids in community-acquired bacterial pneumonia
26 Apr, 2023 | 14:29h | UTCCorticosteroids in Community-Acquired Bacterial Pneumonia: a Systematic Review, Pairwise and Dose-Response Meta-Analysis – Journal of General Internal Medicine (if the link is paywalled, try this one)
Related:
RCT | Hydrocortisone reduces mortality in severe community-acquired pneumonia
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia
Post-tuberculosis lung impairment: systematic review and meta-analysis of spirometry data from 14 621 people
26 Apr, 2023 | 14:11h | UTC
PEEP-test study | The increase in cardiac output induced by a decrease in PEEP reliably detects volume responsiveness
26 Apr, 2023 | 14:03h | UTC
M-A | Prevalence of atypical pathogens in patients with severe pneumonia
26 Apr, 2023 | 14:02h | UTC
RCT | Endosonography with or without confirmatory mediastinoscopy for resectable lung cancer
26 Apr, 2023 | 13:56h | UTC
ASCO Guideline Update | Venous thromboembolism prophylaxis and treatment in patients with cancer
25 Apr, 2023 | 14:49h | UTC
Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary
25 Apr, 2023 | 14:42h | UTCSummary: 2023 GOLD Guidelines for Chronic Obstructive Pulmonary Disease – NEJM Journal Watch (free for a limited period)
Original Guidance: 2023 GOLD REPORT: global strategy for prevention, diagnosis and management of COPD: 2023 Report – Global Initiative for Chronic Obstructive Lung Disease
WHO releases first-ever Standard on universal access to rapid TB diagnostics
24 Apr, 2023 | 14:04h | UTCNews Release: WHO releases first-ever Standard on universal access to rapid TB diagnostics – World Health Organization
WHO Standard: Universal access to rapid tuberculosis diagnostics – World Health Organization
RCT | Oral fluvoxamine plus inhaled budesonide reduced hospitalizations in high-risk patients with early-onset COVID-19
24 Apr, 2023 | 13:51h | UTC
Commentary on Twitter
Treatment w/ oral fluvoxamine + inhaled budesonide among high-risk outpatients w/ early #COVID19 reduced incidence of severe disease requiring advanced care. The combined effect seems to offer benefits over individual use of each drug: https://t.co/wM2da5a5MD pic.twitter.com/Sl1qFzTOjD
— Annals of Int Med (@AnnalsofIM) April 19, 2023
RCT | Higher dose corticosteroids increase mortality in hypoxic COVID-19 patients on simple oxygen
24 Apr, 2023 | 13:55h | UTCEditorial: Higher-dose dexamethasone for patients with COVID-19 and hypoxaemia? – The Lancet
Commentary: Higher-dose corticosteroids tied to 60% more deaths in low-oxygen COVID patients – CIDRAP
Commentary on Twitter (thread – click for more)
Low-dose corticosteroids have been shown to reduce mortality for patients with COVID-19 requiring oxygen or ventilatory support.
A new study evaluated the use of a higher dose of corticosteroids in this patient group. https://t.co/uJGSYSBQAO
— The Lancet (@TheLancet) April 13, 2023
Cold static preservation at 10°C shows promising results for safely extending lung transplantation timeframes
24 Apr, 2023 | 13:38h | UTCExtension of Cold Static Donor Lung Preservation at 10°C – NEJM Evidence
Commentary on Twitter
Donor lungs for transplantation are stored on ice and transplanted as rapidly as possible. In an advance that may ease transplant logistics, Ali et al. now report that prolonged storage of donor lungs at 10°C may lead to equivalent outcomes.
Read the Original Article:
— NEJM Evidence (@NEJMEvidence) April 22, 2023
Brief Review | The use of high-flow nasal oxygen
24 Apr, 2023 | 13:23h | UTCThe use of high-flow nasal oxygen – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
The use of high‑flow nasal oxygen:
💨 acute hypoxemic respiratory failure
💨 acute hypercapnic respiratory failure
💨 weaning from mechanical ventilation
💨 special populations: immunocompromised patients & tracheostomised patients
🖇️ https://t.co/3ZzGabkh0M pic.twitter.com/ieVCWjPDwE— Intensive Care Medicine (@yourICM) April 20, 2023
Brief Review | Aerosolized antibiotics in critical care
24 Apr, 2023 | 13:21h | UTCAerosolised antibiotics in critical care – Intensive Care Medicine
Related: How to Use Nebulized Antibiotics in Severe Respiratory Infections – Antibiotics
Commentary on Twitter
Aerosolised antibiotics in #ICU
💨 delivery to tracheobronchial tree? easy
💨 delivery to infected lung parenchyma? difficult
💨 clinical delivery of aerosolized ABTS
💨 how to address unmet clinical needs from a research standpoint
Free to read #FOAMcc
🖇️ https://t.co/tLjcvyUpY7 pic.twitter.com/brhTAGczRr— Intensive Care Medicine (@yourICM) April 22, 2023
Brief Review | Chronic cough and inflammatory bowel disease: an under-recognized association?
18 Apr, 2023 | 13:07h | UTCChronic cough and inflammatory bowel disease: an under-recognised association? – Breathe
Commentary on Twitter
Breathe: Respiratory complications of inflammatory bowel disease (IBD) are common and may be under-recognised. Chronic cough may present many years after a colectomy for IBD, is typically productive and can be very responsive to inhaled corticosteroids. https://t.co/9hw3bvMeGp pic.twitter.com/ZJURzidpMU
— ERS publications (@ERSpublications) April 15, 2023
SR | Oral direct thrombin inhibitors vs. conventional anticoagulants for the treatment of pulmonary embolism
17 Apr, 2023 | 13:02h | UTC
SR | Exercise‐based rehabilitation programs for pulmonary hypertension
17 Apr, 2023 | 12:44h | UTCExercise‐based rehabilitation programmes for pulmonary hypertension – Cochrane Library
Summary: Exercise-based rehabilitation in pulmonary hypertension – Cochrane Library
SR | Inhaled corticosteroids versus placebo for stable chronic obstructive pulmonary disease
17 Apr, 2023 | 12:40h | UTC
M-A | Association of inhaled corticosteroids with all-cause mortality risk in patients with COPD
12 Apr, 2023 | 13:25h | UTCAssociation of Inhaled Corticosteroids With All-Cause Mortality Risk in Patients With COPD: A Meta-analysis of 60 Randomized Controlled Trials – Chest (link to abstract – $ for full-text)
Commentary on Twitter
ICS-based inhaled therapy of longer than 6 months associated with reduction in all-cause mortality risk in patients with #COPD in a meta-analysis of 60 RCTs. Read the full original research in the January issue: https://t.co/p2CwSu8aqb#journalCHEST #MedEd pic.twitter.com/0j24enQmX3
— CHEST® Journal (@journal_CHEST) January 20, 2023