Chest Medicine
[Press release – Not published yet] Clover’s COVID-19 vaccine candidate demonstrates 79% efficacy against Delta.
30 Sep, 2021 | 10:30h | UTCCommentary: New Chinese vaccine could bolster global arsenal – Science
Randomized trial with over 30.000 patients showed AstraZeneca vaccine was safe and resulted in 74% efficacy against symptomatic SARS-CoV-2 infection.
30 Sep, 2021 | 10:32h | UTC
Commentaries on Twitter
https://twitter.com/NEJM/status/1443331005050355715
https://twitter.com/EricTopol/status/1443336261897392133
Over a third of COVID-19 patients diagnosed with at least one long-COVID symptom.
30 Sep, 2021 | 10:25h | UTCNews release: Over a third of COVID-19 patients diagnosed with at least one long-COVID symptom – University of Oxford
Commentaries:
Two studies tie long COVID-19 to severe initial illness – CIDRAP
Covid: 37% of people have symptoms six months after infection – The Guardian
Long Covid is a bigger problem than we thought – CNN
Supplement: Acute Respiratory Distress Syndrome.
30 Sep, 2021 | 10:03h | UTCHomepage: Acute Respiratory Distress Syndrome – Critical Care Clinics
The Epidemiology of Acute Respiratory Distress Syndrome Before and After Coronavirus Disease 2019
Toward Optimal Acute Respiratory Distress Syndrome Outcomes
Pathophysiology of Acute Respiratory Distress Syndrome and COVID-19 Lung Injury
COVID-19–Associated Acute Respiratory Distress Syndrome
Pathophysiology of the Acute Respiratory Distress Syndrome
Acute Kidney Injury and Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome
Fluid Therapy and Acute Respiratory Distress Syndrome
Pharmacologic Treatments for Acute Respiratory Distress Syndrome
Long-Term Outcomes in Acute Respiratory Distress Syndrome
Related:
Position paper: Advancing precision medicine for acute respiratory distress syndrome.
Review: Personalized mechanical ventilation in acute respiratory distress syndrome.
Seminar | Acute respiratory distress syndrome.
ARDS: Contemporary management and novel approaches during COVID-19
M-A: Efficacy and secondary infection risk of tocilizumab, sarilumab and anakinra in COVID-19 patients.
29 Sep, 2021 | 10:24h | UTC
Characterizing long COVID: a living systematic review.
29 Sep, 2021 | 10:29h | UTCCharacterising long COVID: a living systematic review – BMJ Global Health
Related:
Long Covid – The illness narratives.
New guidelines to help doctors manage long COVID patients published.
M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)
Commentary on Twitter
https://twitter.com/CharitiniSt/status/1442528255718748164
COVID-19 testing moves out of the clinic and into the home.
28 Sep, 2021 | 09:46h | UTCCOVID-19 Testing Moves Out of the Clinic and Into the Home – JAMA
Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.
28 Sep, 2021 | 09:51h | UTCNews release: COVID-19 has caused the biggest decrease in life expectancy since World War II – University of Oxford
Commentaries:
Life expectancy falls in 27 of 29 nations amid COVID-19 – CIDRAP
Covid has wiped out years of progress on life expectancy, finds study – The Guardian
Related:
Just how do deaths due to COVID-19 stack up?
Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.
COVID-19 has caused 6.9 million deaths globally, more than double what official reports show
Commentary on Twitter
The Covid-19 pandemic has resulted in the largest loss of life expectancy since World War II, worst among American menhttps://t.co/7eNCkwBuJA @jm_aburto @UniofOxford @OxfordDemSci @ridhikash07 @melindacmills pic.twitter.com/ckRIDD9G4m
— Eric Topol (@EricTopol) September 27, 2021
Evidence shows that, yes, masks prevent COVID-19 – and surgical masks are the way to go.
28 Sep, 2021 | 09:45h | UTCRelated: [Preprint] Largest study of masks yet details their importance in fighting Covid-19.
Updated WHO Living Guideline: Therapeutics and COVID-19.
26 Sep, 2021 | 22:16h | UTCTherapeutics and COVID-19: living guideline – World Health Organization
WHO Statement: On new recommendation for treatment of COVID-19 patients: WHO calls for equitable access to casirivimab and imdevimab for COVID-19
See also:
WHO recommends antibody treatment for COVID patients at high risk of hospital admission.
Commentary: WHO adds new recommendation for COVID-19 monoclonal antibody combo – CIDRAP
Systematic Review: Non‐invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive sleep apnea.
26 Sep, 2021 | 21:36h | UTC
[Preprint] PRINCIPLE RCT: Colchicine does not improve time to recovery in outpatients with Covid-19 at higher risk of complications.
24 Sep, 2021 | 10:13h | UTC
Commentary on Twitter
While COLCORONA trial found limited evidence that colchicine may reduce COVID-19 related hospitalisation/death
🆕💥💥@TrialPrinciple preprint
Colchicine did NOT improve time to recovery in people at higher risk of complications w COVID-19 in the communityhttps://t.co/2sUoeD7sGV pic.twitter.com/fi2THbxewW— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) September 23, 2021
Systematic Review: Pulmonary rehabilitation for interstitial lung disease.
26 Sep, 2021 | 21:31h | UTCPulmonary rehabilitation for interstitial lung disease – Cochrane Library
Summary: Pulmonary rehabilitation for interstitial lung disease – Cochrane Library
No, vaccinated people are not ‘just as likely’ to spread the Coronavirus as unvaccinated people.
24 Sep, 2021 | 10:06h | UTC
Commentary on Twitter
“Vaccinated people are just as likely to spread the coronavirus.”
This isn't true. But some people — even some very smart people — mistakenly believe this.
Dr. @Craig_A_Spencer explains here why, in this really good piece from @TheAtlantic.https://t.co/9D1dngt3oG
— Paul Sax (@PaulSaxMD) September 23, 2021
WHO recommends antibody treatment for COVID patients at high risk of hospital admission.
24 Sep, 2021 | 10:11h | UTCOriginal article and infographic: A living WHO guideline on drugs for covid-19 – The BMJ
COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants.
24 Sep, 2021 | 10:02h | UTCCOVID-19 vaccines: Keeping pace with SARS-CoV-2 variants – Cell
Commentary on Twitter
https://twitter.com/Sri_Baqri/status/1438865999281983490
Review | Interplay between endocrinology, metabolism, and COVID-19 infection.
24 Sep, 2021 | 10:00h | UTCInterplay between endocrinology, metabolism, and COVID-19 infection – Clinical Medicine Journal
RCT confirms antibiotics are not needed for most children with uncomplicated lower respiratory tract infection if pneumonia is not suspected clinically.
24 Sep, 2021 | 09:00h | UTC
Commentary on Twitter
#Antibiotic resistance is a global public health threat.
New trial indicates, unless pneumonia is suspected, clinicians should provide safety-netting advice but not prescribe antibiotics for most children presenting with chest infections. https://t.co/mOwLG5rZd1 #AMR pic.twitter.com/b0c7Z5flQk
— The Lancet (@TheLancet) September 23, 2021
[Preprint] Third dose of Sinopharm inactivated SARS-CoV-2 vaccine induces robust B and T cell responses.
23 Sep, 2021 | 10:18h | UTCCommentaries:
Sinopharm’s COVID booster reverses antibody decline, enhances cell-based responses – study – Reuters
Review: Focused management of patients with severe acute brain injury and ARDS.
24 Sep, 2021 | 08:52h | UTCFocused Management of Patients with Severe Acute Brain Injury and ARDS – CHEST
Systematic review: Clinical characteristics of multisystem inflammatory syndrome in adults.
23 Sep, 2021 | 10:12h | UTC
Commentary on Twitter
Multisystem inflammatory syndrome has been reported in adults worldwide but may be hard to distinguish from acute biphasic #COVID19 and postacute sequelae of COVID-19. More research is needed to understand this emerging clinical entity. https://t.co/OnerzsZKVB
— JAMA Network Open (@JAMANetworkOpen) September 22, 2021
AHA Scientific Statement: Sleep‐disordered breathing and cardiovascular disease in children and adolescents.
23 Sep, 2021 | 10:02h | UTCNews release: Obstructive sleep apnea is common in kids and may impact blood pressure, heart health – American Heart Association
ERS clinical practice guidelines on treatment of sarcoidosis.
23 Sep, 2021 | 10:00h | UTCERS clinical practice guidelines on treatment of sarcoidosis – European Respiratory Journal
New WHO Global Air Quality Guidelines aim to save millions of lives from air pollution.
23 Sep, 2021 | 10:05h | UTCNews release: New WHO Global Air Quality Guidelines aim to save millions of lives from air pollution – World Health Organization
Original Guideline: WHO global air quality guidelines: particulate matter (PM2.5 and PM10), ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide
Executive Summary: WHO global air quality guidelines: particulate matter (PM2.5 and PM10), ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide
Commentaries:
Millions of deaths could be avoided under new air quality guidelines, WHO says – CNN
WHO slashes guideline limits on air pollution from fossil fuels – The Guardian
Importance of distinguishing between asthma and chronic obstructive pulmonary disease in primary care.
23 Sep, 2021 | 09:57h | UTC