Chest Medicine (all articles)
[Preprint] Third dose of Sinopharm inactivated SARS-CoV-2 vaccine induces robust B and T cell responses.
23 Sep, 2021 | 10:18h | UTCCommentaries:
Sinopharm’s COVID booster reverses antibody decline, enhances cell-based responses – study – Reuters
Review: Focused management of patients with severe acute brain injury and ARDS.
24 Sep, 2021 | 08:52h | UTCFocused Management of Patients with Severe Acute Brain Injury and ARDS – CHEST
Systematic review: Clinical characteristics of multisystem inflammatory syndrome in adults.
23 Sep, 2021 | 10:12h | UTC
Commentary on Twitter
Multisystem inflammatory syndrome has been reported in adults worldwide but may be hard to distinguish from acute biphasic #COVID19 and postacute sequelae of COVID-19. More research is needed to understand this emerging clinical entity. https://t.co/OnerzsZKVB
— JAMA Network Open (@JAMANetworkOpen) September 22, 2021
AHA Scientific Statement: Sleep‐disordered breathing and cardiovascular disease in children and adolescents.
23 Sep, 2021 | 10:02h | UTCNews release: Obstructive sleep apnea is common in kids and may impact blood pressure, heart health – American Heart Association
ERS clinical practice guidelines on treatment of sarcoidosis.
23 Sep, 2021 | 10:00h | UTCERS clinical practice guidelines on treatment of sarcoidosis – European Respiratory Journal
New WHO Global Air Quality Guidelines aim to save millions of lives from air pollution.
23 Sep, 2021 | 10:05h | UTCNews release: New WHO Global Air Quality Guidelines aim to save millions of lives from air pollution – World Health Organization
Original Guideline: WHO global air quality guidelines: particulate matter (PM2.5 and PM10), ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide
Executive Summary: WHO global air quality guidelines: particulate matter (PM2.5 and PM10), ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide
Commentaries:
Millions of deaths could be avoided under new air quality guidelines, WHO says – CNN
WHO slashes guideline limits on air pollution from fossil fuels – The Guardian
Importance of distinguishing between asthma and chronic obstructive pulmonary disease in primary care.
23 Sep, 2021 | 09:57h | UTC
[Press release – not published yet] J&J says booster shot at two months provided 75% protection against moderate to severe COVID-19 globally and 94% of such cases in the U.S.
22 Sep, 2021 | 10:26h | UTCCommentaries:
Johnson & Johnson says additional dose boosts Covid vaccine efficacy – STAT
J&J booster 94% effective against severe COVID, company says – CIDRAP
Two dose version of Johnson & Johnson shot 94% effective against Covid-19, study finds – CNN
Commentaries on Twitter
(thread – click for more)
?BREAKING—At last—new data on 2-doses of Johnson & Johnson's #vaccine (doses 56 days apart) is 94% effective against symptomatic #COVID19, thus comparable to Moderna/Pfizer. And 100% effective against severe COVID. Booster for 1 dose works well too. ?https://t.co/3nPkodOjuG pic.twitter.com/DizjWt9NYX
— Eric Feigl-Ding (@DrEricDing) September 21, 2021
(thread – click for more)
First press released results out for the double-dose J&J vax trial, ENSEMBLE 2. With 2 months between doses, efficacy against moderate to severe/critical increased – didn't provide overall efficacy data though. Adverse reactions similar to 1st dose …1/n https://t.co/BmBVtLvEaW
— Hilda Bastian, PhD (@hildabast) September 21, 2021
Interpreting SARS-CoV-2 Test Results.
22 Sep, 2021 | 10:24h | UTCInterpreting SARS-CoV-2 Test Results – JAMA
Long Covid – The illness narratives.
22 Sep, 2021 | 10:19h | UTCLong Covid – The illness narratives – Social Science & Medicine
Commentary on Twitter
Our qualitative study of Long Covid was the largest sample (114) published to date. We showed, beyond any reasonable doubt, that this illness is NOT limited to 12 predefined tick-box symptoms. Its key characteristic is 'strangeness' and fluctuation. https://t.co/j6z1u0IYOu pic.twitter.com/C8Hyy9DSms
— Trisha Greenhalgh (@trishgreenhalgh) September 18, 2021
RCT: Probiotics do not reduce the incidence of ventilator-associated pneumonia in critically ill patients.
22 Sep, 2021 | 10:03h | UTCEffect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: Probiotic Flops for Ventilator-Associated Pneumonia Prevention – MedPage Today (free registration required)
Cluster RCT: Procalcitonin point-of-care testing may reduce antibiotic prescription for patients with suspected lower respiratory tract infection in primary care.
22 Sep, 2021 | 10:01h | UTC
Cluster RCT: Implementing C reactive protein point-of-care testing in nursing homes may reduce antibiotic prescribing for suspected lower respiratory tract infections.
22 Sep, 2021 | 10:02h | UTC
Guidelines Summary: Management of Indwelling Pleural Catheters.
22 Sep, 2021 | 10:00h | UTC
Residual excessive daytime sleepiness in patients treated for obstructive sleep apnea: guidance for assessment, diagnosis, and management.
22 Sep, 2021 | 09:56h | UTC
M-A: Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19 – According to this analysis, standard-dose prophylactic anticoagulation should be the standard of care for hospitalized patients with COVID-19 who do not have an indication for therapeutic anticoagulation, irrespective of disease severity.
21 Sep, 2021 | 09:54h | UTC
Commentary on Twitter (thread – click for more)
Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with #COVID-19: A systematic review and meta-analysis of randomized controlled trials https://t.co/Gkdfp9vn75 @ESC_Journals @escardio @ESCardioNews #COVID19
— Luis Ortega Paz (@Ortega_Paz) September 15, 2021
COVID will likely shift from pandemic to endemic — but what does that mean?
21 Sep, 2021 | 09:49h | UTCCOVID will likely shift from pandemic to endemic — but what does that mean? – The Conversation
An Update on Coronavirus Disease 2019 (COVID-19) and Pregnancy.
21 Sep, 2021 | 09:51h | UTC
Six rules that will define our second pandemic winter
21 Sep, 2021 | 09:47h | UTCSix Rules That Will Define Our Second Pandemic Winter – The Atlantic
Review: Transfusion-related acute lung injury in the perioperative patient.
21 Sep, 2021 | 08:56h | UTCTransfusion-related Acute Lung Injury in the Perioperative Patient – Anesthesiology
CDC Report: Moderna’s vaccine associated with greater effectiveness (93%) against Covid-19 hospitalization compared to Pfizer (88%) and J&J (71%) vaccines.
19 Sep, 2021 | 23:48h | UTCCommentaries:
CDC: Moderna COVID vaccine most protective against hospital cases – CIDRAP
CDC data: Moderna vaccine has edge in preventing COVID-19 hospitalizations – UPI
Commentary on Twitter
Turns out all vaccines are not equal! https://t.co/yP6eC6o78i via @CDCgov Among adults without immunocompromising conditions, vaccine effectiveness against COVID-19 hospitalization (Mar 11–Aug 15, 21) was ⬆️for @moderna_tx (93%) than @pfizer (88%) and @JNJNews vaccine (71%).
— Carlos del Rio (@CarlosdelRio7) September 17, 2021
Does everybody need a booster shot? – “Why some people might need Covid-19 booster shots — and some might not”.
19 Sep, 2021 | 23:43h | UTCDoes everybody need a booster shot? – Vox
An FDA panel says only high-risk Americans and those 65+ should get covid boosters.
19 Sep, 2021 | 23:45h | UTCAn FDA Panel Says Only High-Risk Americans And Those 65+ Should Get COVID Boosters – NPR
See also:
5 reasons why FDA advisers did not recommend Covid-19 booster shots for everyone – CNN
Top doctors say not so fast to Biden’s boosters-for-all plan – Associated Press
Related:
Third shot: UK to offer COVID booster jabs to over 50s.
COVID-19 vaccine efficacy does not support boosters for general population, review concludes.
COVID vaccine effects wane over time but still prevent death and severe illness.
What’s the evidence for COVID-19 booster shots?
COVID vaccine immunity is waning — how much does that matter? – “As debates about booster shots heat up, what’s known about the duration of vaccine-based immunity is still evolving”.
19 Sep, 2021 | 23:40h | UTCCOVID vaccine immunity is waning — how much does that matter? – Nature
RCT: Rivaroxaban does not have an impact on disease progression and symptoms resolution in high-risk adults with mild COVID-19.
17 Sep, 2021 | 10:19h | UTC