Chest Medicine
RCT: Effect of point-of-care testing for respiratory pathogens on antibiotic use in children.
10 Jun, 2022 | 11:16h | UTC
Commentary on Twitter
In a randomized controlled trial of 1243 children, point-of-care testing for respiratory pathogens did not reduce antibiotic consumption in acutely ill children. https://t.co/KnD4zRx2bf
— JAMA Network Open (@JAMANetworkOpen) June 9, 2022
Study Commentary: Traumatic hemothorax: pigtail vs. chest tube.
10 Jun, 2022 | 10:57h | UTCTraumatic Hemothorax: Pigtail vs Chest Tube – RebelEM
Original Study: The small (14 Fr) percutaneous catheter (P-CAT) versus large (28–32 Fr) open chest tube for traumatic hemothorax: A multicenter randomized clinical trial – Trauma and Acute Care Surgery (link to abstract – $ for full-text)
Systematic Review: Evidence-based perioperative diagnosis and management of pulmonary embolism.
9 Jun, 2022 | 10:34h | UTC
M-A: Efficacy and harms of tocilizumab for the treatment of COVID-19 patients.
8 Jun, 2022 | 11:06h | UTC
M-A: Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19.
8 Jun, 2022 | 11:09h | UTCRelated:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Commentary on Twitter
🆕💥💥Systematic review & meta-analysis @OFIDJournal Intensified anticoagulation has NO effect on mortality among hospitalised #COVID19 & ⬆️bleeding
Possible signal of mortality reduction for non-ICU patients although with low precision& high heterogeneity https://t.co/OqLYScxK53— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 7, 2022
Prospective evaluation of autonomic dysfunction in patients with post-acute sequela of COVID-19.
7 Jun, 2022 | 11:38h | UTCCommentary: Autonomic Dysfunction in Post-Acute Sequela of COVID-19 – American College of Cardiology
RCT: The effect of azithromycin on structural lung disease in infants with cystic fibrosis.
7 Jun, 2022 | 11:29h | UTCThe effect of azithromycin on structural lung disease in infants with cystic fibrosis (COMBAT CF): a phase 3, randomised, double-blind, placebo-controlled clinical trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Review: Dyspnea and cough in a lung transplant recipient.
7 Jun, 2022 | 11:16h | UTCDyspnea and cough in a lung transplant recipient – Cleveland Clinic Journal of Medicine
Special Issue: Covid-19 Infection.
3 Jun, 2022 | 12:04h | UTCHomepage: Covid-19 Infection – Infectious Disease Clinics of North America
Editorial: COVID-19: Where We Are, Where We Need to Be
COVID-19 Pathogenesis and Clinical Manifestations
SARS-CoV-2 Transmission and Prevention in the Era of the Delta Variant
Laboratory Diagnosis for SARS-CoV-2 Infection
Pharmacologic Treatment and Management of Coronavirus Disease 2019
COVID-19 in the Critically Ill Patient
Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
COVID-19 in the Immunocompromised Host, Including People with Human Immunodeficiency Virus
Severe Acute Respiratory Syndrome Coronavirus 2 Infections in Children
Brief Review: Prone position in mechanically ventilated patients.
3 Jun, 2022 | 12:02h | UTCProne position in mechanically ventilated patients – Intensive Care Medicine
Commentary on Twitter
Prone position in mechanically ventilated pts:
➡️ rationale for using
➡️ use of PP in clinical setting & effects on outcome
➡️ how to implement at the bedside
➡️ beds
➡️ maneuver
➡️ concomitant therapeutics
➡️ duration
➡️ adverse events#FOAMcc @yourICM
🖇 https://t.co/9ZWCQrllJ5 pic.twitter.com/6AOfiyyq4q— Intensive Care Medicine (@yourICM) June 2, 2022
Summary of best evidence for enhanced recovery after surgery for patients undergoing lung cancer operations.
3 Jun, 2022 | 11:02h | UTCRelated:
Preoperative exercise training for patients with non‐small cell lung cancer – Cochrane Library
M-A: Dexmedetomidine vs. other sedatives in critically ill mechanically ventilated adults.
3 Jun, 2022 | 11:04h | UTCDexmedetomidine vs other sedatives in critically ill mechanically ventilated adults: a systematic review and meta-analysis of randomized trials – Intensive Care Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Meta-Analysis of 77 randomized trials incl 11,997 patients of Dexmedetomidine vs other sedative drugs showed reduced risks of delirium: RR 0.67, 95%CI 0.55 to 0.81
and less hours on MV and in ICU…
Congratulations @DrDaleNeedham https://t.co/KcSunnPQ3I— Peter Nydahl (@NydahlPeter) June 2, 2022
BSH Guidelines for thrombophilia testing.
2 Jun, 2022 | 11:28h | UTCGuidelines for thrombophilia testing: A British Society for Haematology guideline
NIH Updated Guideline: Antithrombotic therapy in patients with COVID-19.
2 Jun, 2022 | 11:25h | UTCAntithrombotic Therapy in Patients With COVID-19 – National Institutes of Health
M-A: Acute and post-acute COVID-19 presentations in athletes.
2 Jun, 2022 | 11:06h | UTC
Video: Care of patients with new, continuing, or recurring symptoms after acute SARS-CoV-2 infection.
2 Jun, 2022 | 11:04h | UTC
Exercise and acute respiratory infections: might regular exercise help protect us?
2 Jun, 2022 | 10:10h | UTCOriginal Study: Exercise versus no exercise for the occurrence, severity, and duration of acute respiratory infections – Cochrane Library
Retrospective Cohort Study: Racial and ethnic discrepancy in pulse oximetry and delayed identification of treatment eligibility among patients with COVID-19.
1 Jun, 2022 | 11:58h | UTCEditorial: Racial and Ethnic Bias in Pulse Oximetry and Clinical Outcomes
Related:
Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
Commentary on Twitter
This cohort study found overestimation of arterial oxygen saturation levels by pulse oximetry occurred in Asian, Black, and Hispanic patients with #COVID19 and delayed care compared with White patients. https://t.co/ptOVwuUewr @AshFawzyMD @GoldenSherita @AmandaBradke @BTGaribaldi
— JAMA Internal Medicine (@JAMAInternalMed) May 31, 2022
Network Meta-Analysis: Effectiveness of heterologous and homologous covid-19 vaccine regimens.
1 Jun, 2022 | 12:00h | UTCNews Release: Three doses of the same or mixed covid jabs work equally well against infections – BMJ
Commentary: Three jabs best for preventing Covid infections, global analysis finds – The Guardian
Systematic Review: SARS-CoV-2 saliva testing using RT-PCR.
1 Jun, 2022 | 11:42h | UTC
RCTs: Favipiravir treatment of uncomplicated influenza in adults.
1 Jun, 2022 | 11:27h | UTCCommentary: Mixed Bag for Antiviral Favipiravir in Flu — Two phase III trials show conflicting results on clinical improvement – MedPage Today (free registration required)
Cohort Study: A multisystem, cardio-renal investigation of post-COVID-19 illness.
31 May, 2022 | 11:44h | UTCA multisystem, cardio-renal investigation of post-COVID-19 illness – Nature Medicine
Commentaries:
Lingering Symptoms After COVID-19 Tied to Heart, Lung, and Kidney Injury – TCTMD
Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome – News Medical
Commentary on Twitter
Deep clinical phenotyping at 28-60 days post-discharge of patients who had been hospitalized with #COVID19 and subsequent long-term follow up with electronic health records reveals evidence of persistent cardio-renal involvement. #postCOVID @ColinBerryMD https://t.co/uLxtj0b1gJ
— Nature Medicine (@NatureMedicine) May 30, 2022
Systematic Review: Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19.
31 May, 2022 | 11:40h | UTCSummary: How accurate are symptoms and medical examination to diagnose COVID-19? – Cochrane Library
Commentary on Twitter (thread – click for more)
UPDATE JUST PUBLISHED – How accurate are symptoms & medical examination to diagnose #COVID19?
📚@Cochrane_IDG authors looked at the evidence from 42 studies with 52,608 participants in this review.
➡️https://t.co/pbP9BX5Xkm 1/5 pic.twitter.com/bjfb6yVTGg— The Cochrane Library (@CochraneLibrary) May 20, 2022
Systematic Review: Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease.
31 May, 2022 | 11:16h | UTC
Commentary on Twitter
Is magnesium sulfate effective for #COPD flare‐ups? @CochraneAirways systematic review evaluates the evidence from 11 studies. ''Magnesium infusion may ⬇️ hospital admissions, shorten length of hospital stay & improve breathlessness compared to placebo' https://t.co/ZUPVrcdRzk pic.twitter.com/IxBGlnU6FZ
— The Cochrane Library (@CochraneLibrary) May 30, 2022
Hypoxia in the ED setting: systematic approach and management.
31 May, 2022 | 10:56h | UTCHypoxia in the ED Setting: Systematic Approach and Management – emDocs