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Cardiology (all articles)

M-A: Omega-3 fatty acids supplementation is associated with increased risk of atrial fibrillation.

13 Oct, 2021 | 01:27h | UTC

Effect of Long-Term Marine Omega-3 Fatty Acids Supplementation on the Risk of Atrial Fibrillation in Randomized Controlled Trials of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis – Circulation (link to abstract – $ for full-text)

Related:

M-A: Omega-3 fatty acids supplementation increases the risk of atrial fibrillation in patients with lipid disorders.

More data suggests no cardiovascular benefit from Omega-3 supplementation – secondary analysis of STRENGHT trial did not show an association between achieved Omega-3 fatty acid levels and major adverse cardiovascular outcomes in patients with high cardiovascular risk.

RCT: Omega-3 supplements do not reduce cardiovascular events in elderly patients after myocardial infarction

#AHA20 – Randomized trial: High-dose Omega-3 fatty acids did not reduce the risk of cardiac events in patients at high cardiovascular risk

Meta-Analysis of Randomized Trials: Little Benefit from Omega-3 Intake to Reduce Cardiovascular Disease Risk

 

Commentary on Twitter

 

Review: Optimal diet for cardiovascular and planetary health.

13 Oct, 2021 | 01:22h | UTC

Optimal diet for cardiovascular and planetary health – Heart

 

AHA Scientific Statement: Medication Adherence and Blood Pressure Control.

12 Oct, 2021 | 00:09h | UTC

Medication Adherence and Blood Pressure Control: A Scientific Statement From the American Heart Association – Hypertension

News release: Health system crucial to improve medication adherence for people managing hypertension – American Heart Association

Top Things to Know: Medication Adherence and Blood Pressure Control – American Heart Association

Commentary: Medication Adherence – Is It Really the Patient’s Fault? – American Heart Association

 

RCT: In stable patients who have undergone PCI for acute myocardial infarction, de-escalation from aspirin + ticagrelor to aspirin + clopidogrel after 1 month reduced bleeding events without increasing cardiovascular risk.

12 Oct, 2021 | 00:06h | UTC

Unguided de-escalation from ticagrelor to clopidogrel in stabilised patients with acute myocardial infarction undergoing percutaneous coronary intervention (TALOS-AMI): an investigator-initiated, open-label, multicentre, non-inferiority, randomised trial – The Lancet (link to abstract – $ for full-text)

Commentary: Adopting a clopidogrel-based DAPT strategy after PCI boosts outcomes for heart attack patients – Cardiovascular Business

 

Heart-inflammation risk from Pfizer COVID vaccine is very low.

10 Oct, 2021 | 21:42h | UTC

Heart-inflammation risk from Pfizer COVID vaccine is very low – Nature

Original studies:

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

 

Study suggests a 30-second interval between automated office blood pressure measurements is as accurate and reliable as a 60-second interval.

8 Oct, 2021 | 10:09h | UTC

Impact of 30- Versus 60-Second Time Intervals Between Automated Office Blood Pressure Measurements on Measured Blood Pressure – Hypertension (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

7 Oct, 2021 | 10:51h | UTC

Myocarditis after Covid-19 Vaccination in a Large Health Care Organization – New England Journal of Medicine

Commentary: Studies Highlight Rarity of Myocarditis With mRNA COVID-19 Vaccines – TCTMD

Related Study: Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel – New England Journal of Medicine

 

Commentaries on Twitter

 

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

7 Oct, 2021 | 10:49h | UTC

Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel – New England Journal of Medicine

Commentary: Studies Highlight Rarity of Myocarditis With mRNA COVID-19 Vaccines – TCTMD

Related study: Myocarditis after Covid-19 Vaccination in a Large Health Care Organization – New England Journal of Medicine

 

Commentaries on Twitter

 

Sweden, Denmark pause Moderna COVID-19 vaccine for younger age groups.

7 Oct, 2021 | 10:45h | UTC

Sweden, Denmark pause Moderna COVID-19 vaccine for younger age groups – Reuters

 

Varied extent of mitral annular disjunction among cases with different phenotypes of mitral valve prolapse.

7 Oct, 2021 | 10:12h | UTC

Varied Extent of Mitral Annular Disjunction Among Cases With Different Phenotypes of Mitral Valve Prolapse – JACC: Case Reports

 

Commentary on Twitter

 

Cohort study: Adding a new antihypertensive to existing regimens is associated with greater blood pressure reductions than maximizing dose.

6 Oct, 2021 | 09:57h | UTC

Adding a New Medication Versus Maximizing Dose to Intensify Hypertension Treatment in Older Adults: A Prospective Observational Study – Annals of Internal Medicine

News release: When blood pressure needs more control, what’s better: An additional drug or more of the same? – Michigan Medicine

Commentary: Adding an antihypertensive to existing regimens associated with greater BP reduction than maximizing dose, with some caveats in adherence – ACP Internist

Related: #ESCCongress – RCT: Initial hypertension treatment with a single pill with 4 drugs at quarter doses (irbesartan 37.5 mg, amlodipine 1.25 mg, indapamide 0.625 mg, and bisoprolol 2.5 mg) achieved better BP lowering vs. standard monotherapy (irbesartan 150 mg).

 

Commentary on Twitter (thread – click for more)

 

Is salt good for you after all? The evidence says no.

6 Oct, 2021 | 08:52h | UTC

Is salt good for you after all? The evidence says no – The Conversation

Related:

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

Systematic Review: Altered dietary salt intake for people with chronic kidney disease.

New WHO benchmarks help countries reduce salt intake and save lives.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 

Review: Inhibition of platelet aggregation after coronary stenting in patients receiving oral anticoagulation.

6 Oct, 2021 | 08:46h | UTC

Inhibition of Platelet Aggregation After Coronary Stenting in Patients Receiving Oral Anticoagulation – Deutsches Ärzteblatt International

 

Cohort study: Acute myocarditis following COVID-19 mRNA vaccination in adults aged 18 years or older is rare, and most cases are not severe.

5 Oct, 2021 | 10:07h | UTC

Acute Myocarditis Following COVID-19 mRNA Vaccination in Adults Aged 18 Years or Older – JAMA Internal Medicine

Editorial: COVID-19 Messenger RNA Vaccination and Myocarditis—A Rare and Mostly Mild Adverse Effect

 

Commentary on Twitter

 

AHA Scientific Statement: Diagnosis and management of patients with myocardial injury after noncardiac surgery.

5 Oct, 2021 | 09:01h | UTC

Diagnosis and Management of Patients With Myocardial Injury After Noncardiac Surgery: A Scientific Statement From the American Heart Association – Circulation

News Release: 1 in 5 adults has high levels of heart enzymes after any surgery, monitoring advised – American Heart Association

Commentary: AHA: More Screening Needed to Catch Myocardial Injury After Noncardiac Surgery – TCTMD

 

Clinical practice guideline: evidence, recommendations and algorithm for the preoperative optimization of anemia, hyperglycemia and smoking.

5 Oct, 2021 | 08:59h | UTC

Clinical practice guideline: evidence, recommendations and algorithm for the preoperative optimization of anemia, hyperglycemia and smoking – Canadian Journal of Surgery

 

M-A: Beta-blockers do not reduce the risk of major adverse cardiovascular events in patients with stable coronary artery disease without prior myocardial infarction or left ventricular dysfunction.

5 Oct, 2021 | 08:53h | UTC

Meta-Analysis of the Usefulness of Beta-Blockers to Reduce the Risk of Major Adverse Cardiovascular Events in Patients With Stable Coronary Artery Disease Without Prior Myocardial Infarction or Left Ventricular Dysfunction – The American Journal of Medicine (link to abstract – $ for full-text)

 

Cohort study: Statin therapy initiation linked to increased risk of diabetes progression.

5 Oct, 2021 | 08:56h | UTC

Association of Statin Therapy Initiation With Diabetes Progression: A Retrospective Matched-Cohort Study – JAMA Internal Medicine

Commentaries:

Statin Therapy Initiation and Diabetes Progression – American College of Cardiology

Statin Initiation Linked to Greater Progression of Diabetes – HealthDay

Diabetes progression with initiation of statins – MedicalRessearch.com

Related:

Meta-Analysis: Medications that Reduce or Increase the Risk of New Onset Diabetes

Observational Study Points to an Increased Risk of Diabetes Among Patients Using Statins

Another Observational Study Showing Association of Statin Use with Risk of New‐Onset Diabetes Mellitus

Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes

 

Commentary on Twitter

 

Systematic Review: Does testing for cancer in people with unprovoked blood clots in the legs and lungs reduce cancer- and blood clot-related death and illness?

3 Oct, 2021 | 22:33h | UTC

Summary: Does testing for cancer in people with unprovoked blood clots in the legs and lungs reduce cancer- and blood clot-related death and illness? – Cochrane Library

Original article: Effect of testing for cancer on cancer‐ or venous thromboembolism (VTE)‐related mortality and morbidity in people with unprovoked VTE – Cochrane Library

 

RCT: Early computed tomography coronary angiography in patients with suspected acute coronary syndrome did not improve one year clinical outcomes.

3 Oct, 2021 | 22:35h | UTC

Early computed tomography coronary angiography in patients with suspected acute coronary syndrome: randomised controlled trial – The BMJ

 

Commentary on Twitter

 

Coronary microvascular dysfunction: Considerations for diagnosis and treatment.

3 Oct, 2021 | 22:29h | UTC

Coronary microvascular dysfunction: Considerations for diagnosis and treatment – Cleveland Clinic Journal of Medicine

Related:

Cohort study: Clinical characteristics and prognosis of patients with microvascular angina.

Position Paper on ‘Coronary Microvascular Dysfunction in Cardiovascular Disease’

 

Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis.

1 Oct, 2021 | 10:17h | UTC

Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis – PLOS Medicine

Commentaries:

Sticking to low-fat dairy may not be the only heart healthy option, study shows – George Institute for Global Health

Expert reaction to cohort study and review on biomarkers of dairy fat intake, CVD and all-cause mortality – Science Media Centre

People who eat more dairy fat have lower risk of heart disease, study suggests – CNN

 

M-A: Non-alcoholic fatty liver disease linked to increased risk of fatal and non-fatal cardiovascular events.

1 Oct, 2021 | 10:19h | UTC

Non-alcoholic fatty liver disease and risk of fatal and non-fatal cardiovascular events: an updated systematic review and meta-analysis – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

 

Commentary on Twitter

https://twitter.com/LancetGastroHep/status/1440164633805918224

 

Cohort Study: Women treated with radiation therapy for left-sided breast cancer had over twice the risk of subsequent coronary artery disease compared with women treated with radiation therapy for right-sided breast cancer.

1 Oct, 2021 | 10:21h | UTC

Coronary Artery Disease in Young Women After Radiation Therapy for Breast Cancer: The WECARE Study – JACC: CardioOncology

Commentaries:

Left Breast Radiation Therapy Doubles CV Disease Risk vs. Right Breast Radiation Therapy in Young Women – American College of Cardiology

CAD in Young Women After Radiation Therapy for Breast Cancer – American College of Cardiology

 

Commentary on Twitter

 

Cardiac troponin and defining myocardial infarction.

1 Oct, 2021 | 10:11h | UTC

Cardiac troponin and defining myocardial infarction – Cardiovascular Research

 

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