RCT: In stable patients who have undergone PCI for acute myocardial infarction, de-escalation from aspirin + ticagrelor to aspirin + clopidogrel after 1 month reduced bleeding events without increasing cardiovascular risk.
12 Oct, 2021 | 00:06h | UTCUnguided de-escalation from ticagrelor to clopidogrel in stabilised patients with acute myocardial infarction undergoing percutaneous coronary intervention (TALOS-AMI): an investigator-initiated, open-label, multicentre, non-inferiority, randomised trial – The Lancet (link to abstract – $ for full-text)