Coronary Insufficiency
RCT | A double-dose influenza vaccination during hospitalization for acute coronary syndrome did not improve outcomes compared to standard-dose outpatient vaccination.
13 Sep, 2022 | 13:19h | UTC
Commentary on Twitter
In the VIP-ACS trial, among patients hospitalised with an ACS, double dose influenza vaccination before discharge does not reduce cardiovascular and pulmonary outcomes compared with standard dose vaccination ?https://t.co/L9e7MXWfWV#EHJ #ESCCongress @ehj_ed @rladeiraslopes pic.twitter.com/95o50krrwm
— European Society of Cardiology Journals (@ESC_Journals) August 31, 2022
RCT | Effects of Nicorandil administration on infarct size in patients with ST‐Segment–Elevation Myocardial Infarction undergoing primary percutaneous coronary intervention.
11 Sep, 2022 | 22:37h | UTC
Study suggests many stable patients with ST-Elevation Myocardial Infarction may not require routine admission to a cardiac intensive care unit following PCI reperfusion.
8 Sep, 2022 | 14:45h | UTC
#ESCCongress | Study shows long-term Evolocumab appears to be safe in patients with established atherosclerotic cardiovascular disease.
30 Aug, 2022 | 12:12h | UTCNews Release: Long-term evolocumab therapy leads to further reductions in cardiovascular events – European Society of Cardiology
Original Article: Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease – New England Journal of Medicine
Commentary on Twitter
#OriginalResearch SimPub #ESCCongress: In this open-label extension of #FOURIER RCT, long-term evolocumab therapy for >8 yrs was associated w/ persistently low rates and greater reduction in MACE compared w/ delayed treatment initiation among patients w… https://t.co/9g97s4MZSt pic.twitter.com/y5uN53gdKo
— Circulation (@CircAHA) August 29, 2022
#ESCCongress – RCT | In patients with severe ischemic left ventricular systolic dysfunction under optimal medical therapy, revascularization by PCI did not improve outcomes.
29 Aug, 2022 | 12:38h | UTCPercutaneous Revascularization for Ischemic Left Ventricular Dysfunction – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Coronary stenting does not benefit patients with severe left ventricular dysfunction – European Society of Cardiology
Commentary on Twitter
REVIVED-BCIS2: In patients with a low left ventricular ejection fraction and viable myocardium, PCI did not reduce the incidence of death from any cause or hospitalization for heart failure. #ESCCongress https://t.co/XtZlkJ7GAf pic.twitter.com/6uMNemzkyN
— NEJM (@NEJM) August 27, 2022
#ESCCongress – RCT | Routine functional testing is not better than standard care in high-risk patients after percutaneous coronary intervention.
29 Aug, 2022 | 12:32h | UTCRoutine Functional Testing or Standard Care in High-Risk Patients after PCI – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
POST-PCI: In a randomized trial of patients who underwent percutaneous coronary intervention, routine stress testing did not improve clinical outcomes at two years. #ESCCongress https://t.co/nil00HQm4Z pic.twitter.com/o4v0UcDfYV
— NEJM (@NEJM) August 28, 2022
#ESCCongress | In patients within 6 months of a myocardial infarction, a polypill containing aspirin, ramipril, and atorvastatin resulted in a lower risk of major adverse cardiovascular events compared to usual care.
29 Aug, 2022 | 12:27h | UTCPolypill Strategy in Secondary Cardiovascular Prevention – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Polypill reduces cardiovascular events in heart attack patients compared to usual care – European Society of Cardiology
Commentaries:
Polypill Strategy Lowers Adverse CV Event Risk in Secondary Prevention – HCPLive
Related: M-A: Polypills with and without aspirin substantially reduce cardiovascular disease, myocardial infarction, stroke, revascularization, and cardiovascular death in primary cardiovascular disease prevention. (several studies on the subject)
[News release – not published yet] #ESCCongress – RCT | Allopurinol does not improve cardiovascular outcomes in ischemic heart disease patients.
29 Aug, 2022 | 12:15h | UTCCommentary:
ALL-HEART: Gout Drug Allopurinol No Help in CV Prevention – TCTMD
No improvement with allopurinol for patients with ischemic heart disease: ALL-HEART – Cardiology Now
Vasospastic angina: a contemporary review of its pathophysiology, diagnosis and management.
25 Aug, 2022 | 11:53h | UTC
Commentary on Twitter
Almost 50% of angina pts have non obstructive CAD on cath: 3 types of ANOCA & each has its’ own Rx:
?Coronary micro vascular dz B blockers
?Coronary endothelial dysfunction (? Rx)
?Coronary vasospasm (Ca channel blockers/nitrates) @minissianm https://t.co/zJjhEDAs0K pic.twitter.com/zxDjDoM6ru— Ritu Thamman MD (@iamritu) August 20, 2022
M-A | Association of dual antiplatelet therapy with ticagrelor with vein graft failure after coronary artery bypass graft surgery.
10 Aug, 2022 | 15:32h | UTCAssociation of Dual Antiplatelet Therapy With Ticagrelor With Vein Graft Failure After Coronary Artery Bypass Graft Surgery: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Editorial: Balancing the Risks and Benefits of Antiplatelet Therapy After Coronary Artery Bypass Graft Surgery – JAMA (free for a limited period)
Author Interview: Coronary Artery Bypass Surgery in 2022 – JAMA
News Release: Two-medication strategy offers both benefit and risk after coronary artery bypass surgery – Weill Cornell Medicine
Systematic Review | Smoking cessation for secondary prevention of cardiovascular disease.
9 Aug, 2022 | 12:42h | UTCSmoking cessation for secondary prevention of cardiovascular disease – Cochrane Library
Is the contemporary care of older persons with acute coronary syndrome evidence-based?
8 Aug, 2022 | 11:48h | UTC
Commentary from the author on Twitter
♦️Heart disease leading cause of death in older adults
♦️Less likely to receive guideline recommended treatment
♦️Frailty, multi-morbidity linked to worse outcomes
♦️We explore this in our manuscript led by @GregBMills1
?Open access for free download?https://t.co/l452O1QJTJ pic.twitter.com/HCRuwle3KK— Professor Vijay Kunadian (@VijayKunadian) January 29, 2022
RCT | External support for saphenous vein grafts in coronary artery bypass surgery.
26 Jul, 2022 | 11:44h | UTCExternal Support for Saphenous Vein Grafts in Coronary Artery Bypass Surgery: A Randomized Clinical Trial – JAMA Cardiology (link to abstract – $ for full-text)
Commentary on Twitter
This RCT found that the 12-month difference in intimal hyperplasia area between supported and unsupported grafts did not achieve statistical significance, after accounting for early graft occlusions. https://t.co/Qrx3QsmdLc
— JAMA Cardiology (@JAMACardio) July 4, 2022
Open-label RCT | Moderate-intensity statin plus ezetimibe is noninferior to high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease.
20 Jul, 2022 | 12:32h | UTCLong-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease (RACING): a randomised, open-label, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Position Paper | Post-discharge and long-term follow-up after an acute coronary syndrome.
18 Jul, 2022 | 11:22h | UTC
Commentary on Twitter
Post-discharge and long-term follow-up after an acute coronary syndrome: International Collaborative Group of CNCF position paper, by Sabouret et alhttps://t.co/yqPzc0q7ya@SABOURETCardio pic.twitter.com/vd1NTKKZ57
— Giuseppe Biondi-Zoccai (@gbiondizoccai) July 16, 2022
Coronary Artery Disease Reporting and Data System (CAD-RADS 2.0) reporting system for patients undergoing coronary CT angiography.
14 Jul, 2022 | 12:49h | UTCCommentary: SCCT Releases New Expert Consensus Document on CAD Reporting – American College of Cardiology
Secondary analysis of a RCT | Duration of antiplatelet therapy after complex percutaneous coronary intervention in patients at high bleeding risk.
11 Jul, 2022 | 12:06h | UTCCommentaries:
One-Month DAPT Enough for Complex PCI if Bleeding Risk High – Medscape (free registration required)
Commentary on Twitter
Duration of Antiplatelet Therapy After Complex Percutaneous Coronary Intervention In Patients at High Bleeding Risk: a MASTER DAPT trial sub-analysis https://t.co/0FX0Exj8sh @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/Ac8h0AkL42
— European Society of Cardiology Journals (@ESC_Journals) May 31, 2022
RCT | Distal radial vs. conventional radial access for coronary angiography and intervention.
5 Jul, 2022 | 11:54h | UTCEditorial: Less Is More, But Not Always: Distal Transradial Access for Radial Artery Occlusion Prevention
Commentaries:
Distal Radial Access Doesn’t Lower Risk of Occlusion: DISCO RADIAL – TCTMD
Fancy Coronary Access Technique Disappoints in Preventing Radial Artery Occlusions — Distal radial approach did result in easier hemostasis, however – MedPage Today (free registration required)
Commentary on Twitter
New #JACCINT issue is out!
RCT shows no difference in radial artery occlusion between distal radial access and transradial access in patients undergoing diagnostic coronary angiography or #PCI using a 6-F Glidesheath Slender. https://t.co/kk5TKgf9rD#RadialFirst #RAO #RCT pic.twitter.com/484yOB9djM
— JACC Journals (@JACCJournals) June 20, 2022
Guideline Synopsis | Evaluation and diagnosis of chest pain.
4 Jul, 2022 | 12:49h | UTCEvaluation and Diagnosis of Chest Pain – JAMA (free for a limited period)
Original Guideline:
News Release: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released
Guideline Hub: Guideline for the Evaluation and Diagnosis of Chest Pain
Key Points: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology
Commentary: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD
Cohort Study: B‐Type Natriuretic Peptide and long‐term cardiovascular mortality in patients with coronary heart disease.
1 Jul, 2022 | 11:04h | UTC
RCT: Prothrombin complex concentrate vs. plasma for post–cardiopulmonary bypass coagulopathy and bleeding.
30 Jun, 2022 | 10:50h | UTCProthrombin Complex Concentrate vs Plasma for Post–Cardiopulmonary Bypass Coagulopathy and Bleeding: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Commentary on Twitter
In this RCT of cardiac surgical patients, there was no significant difference in postoperative bleeding among patients receiving prothrombin complex concentrates (PCCs) or plasma. Fewer patients with PCCs required intraoperative RBCs after treatment. https://t.co/vqtNX7hQxA
— JAMA Surgery (@JAMASurgery) June 29, 2022
RCT: Effectiveness and safety of early initiation of poststernotomy cardiac rehabilitation exercise training.
23 Jun, 2022 | 12:59h | UTCEffectiveness and Safety of Early Initiation of Poststernotomy Cardiac Rehabilitation Exercise Training: The SCAR Randomized Clinical Trial – JAMA Cardiology (free for a limited period)
Commentary on Twitter
RCT found starting exercise 2 weeks post-sternotomy was as effective as starting at 6 weeks. Clinicians and cardiac rehabilitation professionals can recommend starting exercise training as early as 2 weeks post-sternotomy. https://t.co/MpBhRmyfUh
— JAMA Cardiology (@JAMACardio) June 22, 2022
M-A: Early versus delayed complete revascularization in patients presenting with ST-segment elevation myocardial infarction and multivessel disease.
23 Jun, 2022 | 10:11h | UTC
Cohort Study: Association between short-term, chronic localized and chronic widespread pain and risk for cardiovascular disease.
22 Jun, 2022 | 11:18h | UTC
Safety of bariatric surgery in patients with previous acute coronary events or heart failure: nationwide cohort study.
21 Jun, 2022 | 10:44h | UTC
Commentary on Twitter
#Bariatric surgery improves metabolic health of patients, but what are the risks if they have had MI before surgery?
National dataset matched 16000 pts??
Heart dis assoc w/? cardiac events post op, plus ?risk of SBO and stricture.#SoMe4Surgery https://t.co/iHsZiHIgdG pic.twitter.com/v2SXMpcZd3— BJS Open (@BjsOpen) June 17, 2022