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Cardiac Critical Care

#ESCCongress – RCT | In comatose survivors of out-of-hospital cardiac arrest, targeting a mean arterial blood pressure of 77 mmHg vs. 63 mmHg did not result in different outcomes.

29 Aug, 2022 | 12:13h | UTC

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Trial finds no benefit of raising blood pressure target in post cardiac arrest patients – European Society of Cardiology

Commentary: Blood Pressure Targets Show No Benefit in Comatose Survivors of Cardiac Arrest – HCPLive

 

Commentary on Twitter

 


#ESCCongress – RCT | In comatose survivors of out-of-hospital cardiac arrest, a restrictive vs. a liberal oxygenation strategy resulted in similar incidences of death, severe disability, and coma.

29 Aug, 2022 | 12:12h | UTC

Oxygen Targets in Comatose Survivors of Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Restrictive oxygenation in post cardiac arrest patients is not harmful – European Society of Cardiology

 

Commentary on Twitter

 


Long-term results of a RCT | Vasopressin and methylprednisolone did not improve outcomes in patients with in-hospital cardiac arrest.

24 Aug, 2022 | 14:15h | UTC

Effect of vasopressin and methylprednisolone vs. placebo on long-term outcomes in patients with in-hospital cardiac arrest a randomized clinical trial – Resuscitation

Original Study: RCT: Vasopressin + Methylprednisolone increase the likelihood of return of spontaneous circulation compared to placebo in patients with in-hospital cardiac arrest.

 


Left ventricular assist devices: a primer for the non-mechanical circulatory support provider.

17 Aug, 2022 | 13:51h | UTC

Left Ventricular Assist Devices: A Primer for the Non-Mechanical Circulatory Support Provider – Journal of Clinical Medicine

 


Acute pericarditis: update.

16 Aug, 2022 | 13:28h | UTC

Acute Pericarditis: Update – Current Cardiology Reports

 


Temporal changes, patient characteristics, and mortality, according to microbiological cause of infective endocarditis: a nationwide study.

12 Aug, 2022 | 14:38h | UTC

Temporal Changes, Patient Characteristics, and Mortality, According to Microbiological Cause of Infective Endocarditis: A Nationwide Study – Journal of the American Heart Association

 


Review | How can assessing hemodynamics help to assess volume status?

11 Aug, 2022 | 12:21h | UTC

How can assessing hemodynamics help to assess volume status? – Intensive Care Medicine (free for a limited period)

 


Changes to the European Resuscitation Council guidelines for adult resuscitation.

9 Aug, 2022 | 12:50h | UTC

Changes to the European Resuscitation Council guidelines for adult resuscitation – BJA Education

Related:

2021 Resuscitation Guidelines – Resuscitation Council UK

Executive Summary: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations – Circulation

 


RCT | Effect of high- vs. low-dose tranexamic acid infusion on need for red blood cell transfusion and adverse events in patients undergoing cardiac surgery.

27 Jul, 2022 | 12:21h | UTC

Effect of High- vs Low-Dose Tranexamic Acid Infusion on Need for Red Blood Cell Transfusion and Adverse Events in Patients Undergoing Cardiac Surgery: The OPTIMAL Randomized Clinical Trial – JAMA (free for a limited period)

 

Commentary on Twitter

https://twitter.com/JAMA_current/status/1551960541488451586

 


Cohort Study | Incidence, associated risk factors, and outcomes of postoperative arrhythmia after upper gastrointestinal surgery.

26 Jul, 2022 | 11:52h | UTC

Incidence, Associated Risk Factors, and Outcomes of Postoperative Arrhythmia After Upper Gastrointestinal Surgery – JAMA Network Open

Commentary: Incidence and Outcomes of Postop Arrhythmia After Upper GI Surgery – American College of Cardiology

 

Commentary on Twitter

 


RCT | In patients undergoing cardiac surgery with cardiopulmonary bypass, using a 4% albumin solution for volume expansion did not reduce adverse events compared to ringer acetate.

21 Jul, 2022 | 13:32h | UTC

Effect of 4% Albumin Solution vs Ringer Acetate on Major Adverse Events in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Albumin vs Crystalloid Fluid for Resuscitation in Cardiac Surgery: New Evidence and Arguments in the Timeless Debate – JAMA (free for a limited period)

Commentary: Trial does not support albumin as primer, volume replacement solution in CABG – Healio (free registration required)

 

Commentary on Twitter

https://twitter.com/JAMA_current/status/1549424077298868225

 


High-sensitivity cardiac troponin and the 2021 AHA/ACC Guidelines for the evaluation and diagnosis of acute chest pain.

20 Jul, 2022 | 12:29h | UTC

High-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain – Circulation (free for a limited period)

Summary: High-Sensitivity Cardiac Troponin and the 2021 Guidelines for Acute Chest Pain – American College of Cardiology

 

Commentary on Twitter

 


Review | “No-Reflow” phenomenon.

20 Jul, 2022 | 11:58h | UTC

“No-Reflow” Phenomenon: A Contemporary Review – Journal of Clinical Medicine

 


M-A (mostly of observational studies) | Catheter-directed thrombolysis vs. systemic anticoagulation alone for submassive pulmonary embolism.

15 Jul, 2022 | 12:39h | UTC

Meta-Analysis Comparing Catheter-Directed Thrombolysis Versus Systemic Anticoagulation Alone for Submassive Pulmonary Embolism – American Journal of Cardiology

 


Review | Temporary mechanical circulatory support: devices, outcomes, and future directions.

14 Jul, 2022 | 12:23h | UTC

Temporary mechanical circulatory support: Devices, outcomes, and future directions – The Journal of Heart and Lung Transplantation

 


Retrospective Cohort Study | New-onset atrial fibrillation in intensive care: epidemiology and outcomes.

13 Jul, 2022 | 11:11h | UTC

New-onset atrial fibrillation in intensive care: epidemiology and outcomes – European Heart Journal. Acute Cardiovascular Care

 

Commentary on Twitter

Under a https://creativecommons.org/licenses/by-nc/4.0/ License

 


Navigating a Complicated World | Commentary of the new AHA/ACC Chest Pain Guidelines.

12 Jul, 2022 | 12:40h | UTC

Navigating a Complicated World: The American Heart Association/American College of Cardiology/American College of Chest Physicians/Society of Academic Emergency Medicine/Society of Cardiovascular Computed Tomography/Society of Cardiovascular Magnetic Resonance Chest Pain Guidelines – CHEST

Original Guideline: 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines – Journal of the American College of Cardiology

News Release: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released

Guideline Hub: Guideline for the Evaluation and Diagnosis of Chest Pain

Key Points: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology

Commentary: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD

 


AHA Scientific Statement | Escalating and de-escalating temporary mechanical circulatory support in cardiogenic shock.

8 Jul, 2022 | 12:05h | UTC

Escalating and De-escalating Temporary Mechanical Circulatory Support in Cardiogenic Shock: A Scientific Statement From the American Heart Association – Circulation

Top Things to Know: Escalating and De-escalating Temporary Mechanical Circulatory Support in Cardiogenic Shock– American Heart Association

Commentary: Guiding Cardiogenic Shock Management: Filling in the (Wide) Data Gaps – American Heart Association

 


M-A | Anticoagulants for thrombosis prophylaxis in acutely ill patients admitted to hospital.

5 Jul, 2022 | 12:19h | UTC

Anticoagulants for thrombosis prophylaxis in acutely ill patients admitted to hospital: systematic review and network meta-analysis – The BMJ


Guideline Synopsis | Evaluation and diagnosis of chest pain.

4 Jul, 2022 | 12:49h | UTC

Evaluation and Diagnosis of Chest Pain – JAMA (free for a limited period)

Original Guideline:

2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines – Journal of the American College of Cardiology

News Release: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released

Guideline Hub: Guideline for the Evaluation and Diagnosis of Chest Pain

Key Points: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology

Commentary: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD


RCT: Effects of early Empagliflozin initiation on diuresis and kidney function in patients with acute decompensated heart failure.

30 Jun, 2022 | 11:24h | UTC

Effects of Early Empagliflozin Initiation on Diuresis and Kidney Function in Patients With Acute Decompensated Heart Failure (EMPAG-HF) – Circulation

 


RCT: Prothrombin complex concentrate vs. plasma for post–cardiopulmonary bypass coagulopathy and bleeding.

30 Jun, 2022 | 10:50h | UTC

Prothrombin Complex Concentrate vs Plasma for Post–Cardiopulmonary Bypass Coagulopathy and Bleeding: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)

 

Commentary on Twitter

https://twitter.com/JAMASurgery/status/1542176079728738305

 


Retrospective Cohort Study: Atrial fibrillation after surgery is linked to an increased risk of hospitalization for heart failure.

29 Jun, 2022 | 10:52h | UTC

News Release: Atrial fibrillation after surgery is linked to an increased risk of hospitalization for heart failure – European Society of Cardiology

Original Study: Post-operative atrial fibrillation and risk of heart failure hospitalization – European Heart Journal

Editorial: Post-operative AF and heart failure hospitalizations: what remains hidden in patients undergoing surgery – European Heart Journal

 

Commentary on Twitter

 


Epidemiology of myocarditis and pericarditis following mRNA vaccination by vaccine product, schedule, and interdose interval among adolescents and adults in Ontario, Canada.

27 Jun, 2022 | 11:51h | UTC

Epidemiology of Myocarditis and Pericarditis Following mRNA Vaccination by Vaccine Product, Schedule, and Interdose Interval Among Adolescents and Adults in Ontario, Canada – JAMA Network Open

Commentary: Young Men’s Myocarditis Risk 5 Times Higher With Moderna vs Pfizer Vax — But Canadian study finds that 8-week interval before second dose attenuates some of the risk – MedPage Today (free registration required)

 


M-A: Hypothermic vs. normothermic temperature control after cardiac arrest.

24 Jun, 2022 | 11:51h | UTC

Hypothermic versus Normothermic Temperature Control after Cardiac Arrest – NEJM Evidence

Related:

ERC-ESICM guidelines on temperature control after cardiac arrest in adults – Intensive Care Medicine (if the link is paywalled, try this one)

Target temperature management following cardiac arrest: a systematic review and Bayesian meta-analysis – Critical Care

Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets – Intensive Care Medicine

Targeted Temperature Management for Cardiac Arrest Due to Non-shockable Rhythm: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Frontiers in Medicine

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial – JAMA

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest – New England Journal of Medicine

 


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