Allergy & Immunology
An mRNA vaccine against SARS-CoV-2 — preliminary report
15 Jul, 2020 | 08:25h | UTCAn mRNA Vaccine against SARS-CoV-2 — Preliminary Report – New England Journal of Medicine
Editorial: The Covid-19 Vaccine-Development Multiverse – New England Journal of Medicine
Commentaries: Experimental COVID-19 vaccine safe, generates immune response – NIH News Release AND First data for Moderna Covid-19 vaccine show it spurs an immune response – STAT
Perspective – “My patient caught Covid-19 twice. So long to herd immunity hopes”
14 Jul, 2020 | 08:19h | UTCMy patient caught Covid-19 twice. So long to herd immunity hopes. – Vox
A new understanding of herd immunity
14 Jul, 2020 | 08:23h | UTCA New Understanding of Herd Immunity – The Atlantic
A perspective on potential antibody-dependent enhancement of SARS-CoV-2
14 Jul, 2020 | 08:17h | UTCA perspective on potential antibody-dependent enhancement of SARS-CoV-2 – Nature
Related Commentary on Twitter
The enhancement of disease by antibody-dependent mechanisms (ADE) looms as a/the major concern for #SARSCoV2 vaccines and neutralizing antibodies. A new @nature perspective, explainer, and details of what needs to be donehttps://t.co/0c1Nx92B6v pic.twitter.com/DoflhwpR9A
— Eric Topol (@EricTopol) July 13, 2020
Case Reports: 2 Adults with Kawasaki-like Multisystem Inflammatory Syndrome Associated with COVID-19
13 Jul, 2020 | 00:05h | UTCCase Report 1: An adult with Kawasaki-like multisystem inflammatory syndrome associated with COVID-19 – The Lancet
Case Report 2: An adult presentation consistent with PIMS-TS – The Lancet Rheumatology
Related Commentary on Twitter
First reports of Kawasaki-like #SARSCoV2 multi-system inflammatory syndrome in adultshttps://t.co/FYNWlxdk9q @TheLancet https://t.co/lnHMUxA7Ux @TheLancetRheum
21 yo in London, 45 yo in New York City pic.twitter.com/lLmSRzBjs4— Eric Topol (@EricTopol) July 11, 2020
Observational Analysis: BCG Vaccine and COVID-19
13 Jul, 2020 | 00:02h | UTCCommentaries: Expert reaction to study looking at BCG vaccination programmes and COVID-19 deaths in different countries – Science Media Centre AND Preliminary study suggests tuberculosis vaccine may be limiting COVID-19 deaths – Virginia Tech
[Abstract Only] Randomized Trial: Intravenous Cetirizine Versus Intravenous Diphenhydramine for the Treatment of Acute Urticaria
12 Jul, 2020 | 23:57h | UTCIntravenous Cetirizine Versus Intravenous Diphenhydramine for the Treatment of Acute Urticaria: A Phase III Randomized Controlled Noninferiority Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
[Abstract Only] Randomized Trial: Ruxolitinib Cream for Treatment of Vitiligo
12 Jul, 2020 | 23:58h | UTCRuxolitinib cream for treatment of vitiligo: a randomised, controlled, phase 2 trial – The Lancet
Related Commentary on Twitter
NEW—Treatment with ruxolitinib cream was associated with substantial repigmentation of vitiligo lesions up to 52 weeks of treatment, and all doses were well tolerated: finding from a randomised, controlled, phase 2 trial https://t.co/Td5nlsMcYI pic.twitter.com/CHvtspGstQ
— The Lancet (@TheLancet) July 10, 2020
Developing a SARS-CoV-2 Vaccine at Warp Speed
7 Jul, 2020 | 08:59h | UTCDeveloping a SARS-CoV-2 Vaccine at Warp Speed – JAMA
Related Video: Coronavirus Vaccine Development – JAMA
Study Addresses Clinical Validity and Utility of Serum Antibodies to SARS-CoV-2
7 Jul, 2020 | 08:55h | UTC
Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy
7 Jul, 2020 | 08:43h | UTCA Clinical Pharmacologist’s Perspective on Penicillin Allergy – JAMA
Editorial: Is a “Cytokine Storm” Relevant to COVID-19?
1 Jul, 2020 | 07:59h | UTCIs a “Cytokine Storm” Relevant to COVID-19? – JAMA Internal Medicine
Related Commentary on Twitter
NEW @JAMAInternalMed
Is a “Cytokine Storm” Relevant to #COVID19 ?
"Although the term cytokine storm conjures up dramatic imagery and has captured the attention of the mainstream and scientific media, the current data do not support its use"https://t.co/0NuCUHdBdq— Antibiotic Steward? Bassam Ghanem (@ABsteward) June 30, 2020
[Preprint] Immunity to COVID-19 is Probably Higher than Tests Have Shown
30 Jun, 2020 | 08:04h | UTCImmunity to COVID-19 is probably higher than tests have shown – Karolinska Institutet
Original Study: Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19 – bioRxiv
Studies: Childhood Multisystem Inflammatory Syndrome — A New Challenge in the Pandemic
30 Jun, 2020 | 07:57h | UTCStudy 1: Multisystem Inflammatory Syndrome in U.S. Children and Adolescents – New England Journal of Medicine
Study 2: Multisystem Inflammatory Syndrome in Children in New York State – New England Journal of Medicine
Commentaries: Worrisome details noted in kids with COVID inflammatory syndrome – CIDRAP AND Researchers report nearly 300 cases of inflammatory syndrome tied to Covid-19 in kids – STAT
Opinion – Coronavirus: Could it be Burning out After 20% of a Population is Infected?
30 Jun, 2020 | 08:00h | UTCCoronavirus: could it be burning out after 20% of a population is infected? – The Conversation
Covid-19 Antibody Tests: A Briefing
26 Jun, 2020 | 09:17h | UTCCovid-19 antibody tests: a briefing – The BMJ
Commentary: Coronavirus: Antibody test lacks ‘proper assessment’ – BBC
Systematic Review: Antibody Tests for Identification of Current and Past Infection with SARS‐CoV‐2
26 Jun, 2020 | 09:19h | UTCAntibody tests for identification of current and past infection with SARS‐CoV‐2 – Cochrane Library
News Release: New Cochrane review assesses how accurate antibody tests are for detecting COVID-19 – Cochrane Library
Commentaries: New Cochrane review assesses how accurate antibody tests are for detecting COVID-19 – Wiley AND Expert reaction to Cochrane Review of antibody tests for SARS-CoV-2 – Science Media Centre AND Covid-19: Timing is critical for antibody tests, finds Cochrane review – The BMJ
Perspective: “I’m a Viral Immunologist. Here’s What Antibody Tests for Covid-19 Tell Us”
26 Jun, 2020 | 09:15h | UTCI’m a viral immunologist. Here’s what antibody tests for Covid-19 tell us – The Guardian
[Preprint] Intrafamilial Exposure to SARS-CoV-2 Induces Cellular Immune Response without Seroconversion
25 Jun, 2020 | 08:21h | UTCCommentary: Exposure to SARS-CoV-2 can induce virus-specific T cell responses without seroconversion – News Medical
A Compendium Answering 150 Questions on COVID‐19 and SARS‐CoV‐2
23 Jun, 2020 | 08:38h | UTCA compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2 – Allergy
Study: Coronavirus Antibodies Can Disappear After a Few Months
21 Jun, 2020 | 23:46h | UTCClinical and immunological assessment of asymptomatic SARS-CoV-2 infections – Nature Medicine
Commentaries: Chinese study: Antibodies in COVID-19 patients fade quickly – CIDRAP AND Coronavirus antibodies may disappear 2 to 3 months after people recover, a new study found – Business Insider AND New insights can change everything we know about coronavirus antibodies – BGR – News Beezer AND Expert reaction to study looking at the immune response of 37 asymptomatic people with confirmed SARS-CoV-2 infection – Science Media Centre AND You May Have Antibodies After Coronavirus Infection. But Not for Long – The New York Times
The Science Behind the Search for a Covid-19 Vaccine
17 Jun, 2020 | 02:37h | UTCThe Science Behind the Search for a Covid-19 Vaccine – University of Melbourne
COVID-19 Vaccine Development Pipeline Gears Up
5 Jun, 2020 | 04:59h | UTCCOVID-19 vaccine development pipeline gears up – The Lancet
Perspective: Why a Vaccine May Not be Enough to End the Pandemic
4 Jun, 2020 | 04:54h | UTCWhy a vaccine may not be enough to end the pandemic – Vox
[Abstract Only] Analysis: Milk Allergy Guidelines May Cause Overdiagnosis in Babies and Children
3 Jun, 2020 | 03:33h | UTCMilk Allergy Guidelines may Cause Overdiagnosis in Babies and Children – Imperial College London
Original Study: Assessment of Evidence About Common Infant Symptoms and Cow’s Milk Allergy – JAMA Pediatrics (link to abstract – $ for full-text)