All Posts
Review: Surgery for Spontaneous Intracerebral Hemorrhage
10 Mar, 2020 | 10:21h | UTCSurgery for spontaneous intracerebral hemorrhage – Critical Care (free)
Clinical Update: Diagnosis and Treatment of Clostridioides (Clostridium) difficile Infection in Adults in 2020
10 Mar, 2020 | 08:32h | UTCDiagnosis and Treatment of Clostridioides (Clostridium) Difficile Infection in Adults in 2020 – JAMA (free for a limited period)
Related: Clostridioides Difficile: Diagnosis and Treatments (free BMJ review and guidelines on the subject) AND Clostridioides difficile (formerly Clostridium difficile) infection in the critically ill: an expert statement – Intensive Care Medicine (free)
Randomized Trial: Efficacy of Gabapentin for the Treatment of Alcohol Use Disorder in Patients with Alcohol Withdrawal Symptoms
10 Mar, 2020 | 08:27h | UTCEfficacy of Gabapentin for the Treatment of Alcohol Use Disorder in Patients With Alcohol Withdrawal Symptoms: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Commentaries: Drug eases withdrawal, improves abstinence in alcohol use disorder – UPI (free) AND Gabapentin Found to Work Best for Those With Severe Alcohol Withdrawal Syndrome – Psychiatric News Alert (free)
Clinical Guideline for Homeless and Vulnerably Housed People, and People with Lived Homelessness Experience
10 Mar, 2020 | 10:18h | UTCCommentary: Comprehensive new clinical guideline on homelessness released – News Medical (free)
Improving Physician Communication About Treatment Decisions: Reconsideration of “Risks vs Benefits”
10 Mar, 2020 | 10:20h | UTCImproving Physician Communication About Treatment Decisions: Reconsideration of “Risks vs Benefits” – JAMA (free for a limited period)
Perspective – Can You Sue an Algorithm for Malpractice? It Depends
10 Mar, 2020 | 10:19h | UTCCan you sue an algorithm for malpractice? It depends – STAT (free)
ESA/ESICM Guideline: Noninvasive Respiratory Support in the Hypoxemic Peri-operative/Periprocedural Patient
8 Mar, 2020 | 20:44h | UTC
[Abstract Only] Randomized Trial: Hippocampal Avoidance During Whole-Brain Radiotherapy for Patients with Brain Metastases
10 Mar, 2020 | 10:17h | UTCHippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001 – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentaries: Hippocampal avoidance during WBRT reduces risks on NRG Oncology trial – NRG Oncology (free) AND ‘Practice-Changing’ Study on WBRT for Patients With Brain Mets – Medscape (free registration required)
[Abstract Only] Adjunctive Strategies Underused in Moderate to Severe ARDS, International Study Finds
8 Mar, 2020 | 20:41h | UTCOriginal Study: Patterns of use of adjunctive therapies in patients with early moderate- severe Acute Respiratory Distress syndrome: Insights from the LUNG SAFE Study – CHEST (link to abstract – $ for full-text)
Meta-Analysis: T-piece vs. Pressure Support Ventilation as Spontaneous Breathing Trials in Critically Ill Patients
8 Mar, 2020 | 20:43h | UTC
Related Commentary on Twitter
#CritCare #OpenAccesshttps://t.co/bC8CLs77Hz#Mechanicalventilation is often required in critical patients, but several problems can impair the successful separation of the patient from the #ventilator#FOAMed #FOAMcc #BMC #CriticalCare #ICU #SBT #breathing #systematic #review pic.twitter.com/jDd5xp95Ru
— Critical Care (@Crit_Care) March 8, 2020
Review: Medical Reversals in Family Practice
8 Mar, 2020 | 20:40h | UTCMedical Reversals in Family Practice: A Review – Current Therapeutic Research (free PDF)
Related: Meta-Research: A Comprehensive Review of Randomized Trials Leading to “Medical Reversals” in Three Medical Journals (free)
Choosing Wisely in Rhinology: Five Things Physicians and Patients Should Question
8 Mar, 2020 | 20:38h | UTCChoosing Wisely Canada rhinology recommendations – Journal of Otolaryngology – Head & Neck Surgery (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
[Abstract Only] Cohort Study: Sleep Irregularity Linked to Increased Risk of Cardiovascular Events
8 Mar, 2020 | 20:33h | UTCSleep Irregularity and Risk of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Sleep Irregularity and Risk of Cardiovascular Events – American College of Cardiology (free) AND Better Sleep Linked With Reduced Risk of CVD, Improved Weight Loss – AJMC (free) AND Poor Sleepers at Higher Risk of CVD, MESA Data Suggest – TCTMD (free) AND Irregular sleep may increase risk of cardiovascular events – Brigham and Women’s Hospital (free) AND Irregular sleep may increase risk of cardiovascular problems – Medical News Today (free)
Ten Simple Rules to Becoming a Principal Investigator
8 Mar, 2020 | 20:37h | UTCTen Simple Rules to becoming a principal investigator – PLOS Computational Biology (free)
Related Commentary on Twitter
Read this article if you are wondering what is wrong in academia.
Spoiler: research integrity didn't make the 10 most important rules for becoming a PIhttps://t.co/BjhuaFuJGb pic.twitter.com/IJxBmouIBd
— Maarten van Smeden (@MaartenvSmeden) March 6, 2020
[Abstract Only] Cohort Study: Substituting Margarine, Butter, Mayonnaise, and Dairy Fat with Olive Oil Could Lead to Lower Risk of Cardiovascular Disease
8 Mar, 2020 | 20:31h | UTCOlive Oil Consumption and Cardiovascular Risk in U.S. Adults – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Olive Oil Consumption and Cardiovascular Risk – American College of Cardiology (free) AND Higher Olive Oil Consumption Tied to Lower CVD Risk in U.S. Adults – NEJM Journal Watch (free) AND Use Olive Oil Instead of Saturated Fats for Heart Health, Study Suggests – CardioSmart (free)
Review: Other Primary Headaches—Thunderclap-, Cough-, Exertional-, and Sexual Headache
8 Mar, 2020 | 20:34h | UTC
Guideline: Normal Reference Intervals for Cardiac Dimensions and Function for use in Echocardiographic Practice
8 Mar, 2020 | 20:25h | UTC
Guideline: Echocardiographic Assessment of the Right Heart in Adults
8 Mar, 2020 | 20:27h | UTC
Consensus Statement: Measuring Pelvic Floor Disorder Symptoms Using Patient-Reported Instruments
8 Mar, 2020 | 20:24h | UTC
Short Review: Drug Interactions with Cannabinoids
8 Mar, 2020 | 20:23h | UTCDrug interactions with cannabinoids – Canadian Medical Association Journal (free)
Study: Surgery to Fix the Womb in Position after Prolapse is an Alternative to Hysterectomy
8 Mar, 2020 | 20:20h | UTCSurgery to fix the womb in position after prolapse is an alternative to hysterectomy – NIHR Signal (free)
Original Study: Sacrospinous hysteropexy versus vaginal hysterectomy with uterosacral ligament suspension in women with uterine prolapse stage 2 or higher: observational follow-up of a multicentre randomised trial – The BMJ (free)
Albumin in Decompensated Cirrhosis: New Concepts and Perspectives
8 Mar, 2020 | 20:23h | UTCAlbumin in decompensated cirrhosis: new concepts and perspectives – Gut (free)
NCCN Guidelines Insights: Management of Immunotherapy-Related Toxicities
8 Mar, 2020 | 20:19h | UTCRelated Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)
Related Reviews: A review of cancer immunotherapy toxicity – CA: A Cancer Journal for Clinicians (free) AND Immune Checkpoint Inhibitor Toxicities – Mayo Clinic Proceedings (free) AND New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free) AND Severe toxicity from checkpoint protein inhibitors: What intensive care physicians need to know? – Annals of Intensive Care (free) AND Checkpoint Inhibitors: The diagnosis and treatment of side effects – Deutsches Ärzteblatt international (free)
[Abstract Only] Randomized Trial: Pembrolizumab for Early Triple-Negative Breast Cancer
8 Mar, 2020 | 20:17h | UTCPembrolizumab for Early Triple-Negative Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Neoadjuvant and Adjuvant Pembrolizumab in Early Triple-Negative Breast Cancer – ASCO Post (free)
Study: Structured Nurse Ward Rounds Support Accountability and Risk Management but Not Nurse-patient Communication
8 Mar, 2020 | 20:21h | UTCStructured nurse ward rounds support accountability and risk management but not nurse-patient communication – NIHR Signal (free)
Original Study: Intentional rounding in hospital wards to improve regular interaction and engagement between nurses and patients: a realist evaluation – Health Services and Delivery Research (free)