All Posts
Study finds increased COVID-19 mortality among adults with Down syndrome
26 Feb, 2021 | 08:39h | UTCCommentaries: Adults with Down syndrome 3 times more likely to die of COVID, study finds – CIDRAP AND International study finds increased COVID-19 mortality among adults with Down syndrome – Case Western Reserve University
Related: COVID-19 is 10 times deadlier for people with Down syndrome, raising calls for early vaccination – Science (a few articles per month are free)
COVID-19 hospitalizations attributable to cardiometabolic conditions
26 Feb, 2021 | 08:40h | UTCCommentary: Study estimates two-thirds of COVID-19 hospitalizations due to four conditions – Tufts University
Commentary on Twitter
https://twitter.com/Dmozaffarian/status/1364993823370338312
Opinion – Catching COVID from surfaces is very unlikely. So perhaps we can ease up on the disinfecting
26 Feb, 2021 | 08:38h | UTCRelated: Coronavirus is in the air — there’s too much focus on surfaces – Nature AND COVID-19 rarely spreads through surfaces. So why are we still deep cleaning? – Nature
Ghana receives first historic shipment of COVID-19 vaccinations from international COVAX facility
25 Feb, 2021 | 09:12h | UTCSee also: Ghana becomes recipient of historic first shipment of COVAX vaccines – World Health Organization
Commentaries: Covax vaccine-sharing scheme delivers first doses to Ghana – BBC AND Covax delivers first Covid vaccines in ‘momentous occasion’ – The Guardian AND COVAX delivers its first vaccine shots with shipment to Ghana – Reuters
Cohort study: A single conventional Troponin combined with HEART score may be as good as serial measurements for safe discharge of patients with chest pain in the ED
26 Feb, 2021 | 08:32h | UTCEditorial: Troponin Testing in the Emergency Department—When 2 Become 1
Commentary: Single Troponin Test May Be Enough for Safe Discharge of Chest Pain Patients – TCTMD
RCT: Effect of screening by clinical breast examination on breast cancer incidence and mortality after 20 years
26 Feb, 2021 | 08:34h | UTCCommentaries: The story of the Mumbai breast screening study – The BMJ Opinion
This trial found that regular breast examination by trained female health workers in Mumbai led to earlier diagnosis and reduced deaths from breast cancer in women aged 50 and olderhttps://t.co/TQCHLbVO8L
— The BMJ (@bmj_latest) February 25, 2021
CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma
26 Feb, 2021 | 08:31h | UTCOriginal study: Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma – New England Journal of Medicine
Editorial: Five principles for the intelligent use of AI in medical imaging
26 Feb, 2021 | 08:29h | UTCFive principles for the intelligent use of AI in medical imaging – Intensive Care Medicine
Commentary on Twitter
5 key principles that should be remembered for smart use of #ArtificialIntelligence as adoption of #MachineLearning systems becomes more widespread in medical imaging:
➡️knowledge base
➡️metrics
➡️bias
➡️model fragility
➡️error-prone behavior#DataScience https://t.co/h1iFAyCq35 pic.twitter.com/OvNVtwfl94— Intensive Care Medicine (@yourICM) January 17, 2021
Integrated palliative and oncology care for patients receiving treatment for acute myeloid leukemia
26 Feb, 2021 | 08:25h | UTCOriginal article: Effectiveness of Integrated Palliative and Oncology Care for Patients With Acute Myeloid Leukemia: A Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Decreasing patient-reported burden of treatment: A systematic review of quantitative interventional studies
26 Feb, 2021 | 08:21h | UTC
Phase 2 trial: Muscarinic cholinergic receptor agonist and peripheral antagonist for schizophrenia
26 Feb, 2021 | 08:30h | UTCMuscarinic Cholinergic Receptor Agonist and Peripheral Antagonist for Schizophrenia – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Phase II Results Promising for New Schizophrenia Drug Combo – MedPage Today
Systematic Review: Insufficient evidence to decide whether surgical intervention is beneficial or harmful for the early management of Bell’s palsy
26 Feb, 2021 | 08:20h | UTCSurgical interventions for the early management of Bell’s palsy – Cochrane Library
Summary: Surgical operation for Bell’s palsy (idiopathic facial paralysis) – Cochrane Library
Myocarditis and inflammatory cardiomyopathy: current evidence and future directions
26 Feb, 2021 | 08:18h | UTCMyocarditis and inflammatory cardiomyopathy: current evidence and future directions – Nature Reviews Cardiology (free for a limited period)
Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis
26 Feb, 2021 | 08:17h | UTC
Randomized trial: Oral Azacitidine maintenance therapy for acute myeloid leukemia in first remission
26 Feb, 2021 | 08:23h | UTCOral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Maintenance Oral Azacitidine for Patients With AML in First Remission: QUAZAR AML-001 Trial – The ASCO Post
Study: Unhealthy alcohol use common after bariatric surgery
26 Feb, 2021 | 08:14h | UTCCommentaries: Unhealthy Alcohol Use—A Common Iatrogenic Complication of Bariatric Surgery – JAMA Network Open AND Bariatric Surgery May Increase Risk of Unhealthy Alcohol Use – Psychiatric News Alert AND Bariatric Surgery Ups Risk of Alcohol Abuse – Physician’s Weekly
Commentary on Twitter
Our team’s analysis of VA bariatric surgery outcomes. Alcohol use increased 3–8 years after surgery. The benefits far outweigh the risks, but we need to support our patients long-term. @davearterburn @NeilFlochMD https://t.co/QpGHeRrI9l via @JAMANetworkOpen part of @JAMANetwork
— Luke Funk, MD, MPH (@lmfunk2) December 26, 2020
Guidelines for the treatment of irritable bowel syndrome
26 Feb, 2021 | 08:15h | UTC
RCT: Dimenhydrinate and metoclopramide equally effective in the treatment of nausea due to vertigo
26 Feb, 2021 | 08:12h | UTCComparison of efficacy dimenhydrinate and metoclopramide in the treatment of nausea due to vertigo; a randomized study – The American Journal of Emergency Medicine (link to abstract – $ for full-text)
Series of n-of-1 trials show no difference in muscle symptoms in patients receiving placebo or statins
25 Feb, 2021 | 08:54h | UTCCommentary: Do statins cause muscle symptom side effects? – The BMJ Opinion AND Study: Muscle Symptoms Didn’t Differ Between Statin and Placebo Periods – NEJM Journal Watch
Related study: #AHA20 – In patients who had discontinued statins because of side effects, a N-of-1 trial of a statin, placebo, or no treatment found that side effects often attributed to statins were the same for those taking a placebo (study and commentaries)
Consensus statement on the prevention of opioid‐related harm in adult surgical patients
25 Feb, 2021 | 08:41h | UTCCommentary: Stopping opioid-related addiction, harm and accidents after surgery – AAGBI
Commentary on Twitter
The prevention of opioid‐related harm in adult surgical patients.@nicholasalevy @jane_quinlan @elboghdadly @billfawcett @VandanaChaukar @FeliciaJCox @HansDonaldeBoer @EMARIANOMD @ProfMikeScott @DL08OMD
📄https://t.co/DMO4bPJQTv
🎥https://t.co/OM6fp3zKjC— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) February 22, 2021
RCT: Effect of high-dose subcutaneous Semaglutide vs. placebo in adults with overweight or obesity
25 Feb, 2021 | 08:52h | UTCRelated study: Once-weekly, high-dose semaglutide is effective for improving overweight or obesity among non-diabetic adults – New England Journal of Medicine (study and commentary)
Commentary on Twitter
In this RCT, once-weekly subcutaneous semaglutide used as an adjunct to intensive behavioral therapy & low-calorie diet led significantly greater weight loss vs placebo over 68 weeks among adults w #overweight or #obesity w/o #diabetes https://t.co/xFedvckUUj @PennMedicine #STEP3
— JAMA (@JAMA_current) February 24, 2021
Cohort study: High glycemic index diets are linked to increased risk of cardiovascular disease and death
25 Feb, 2021 | 08:49h | UTCCommentaries: Study finds diet high in poor quality carbohydrates increases heart disease and death – McMaster University AND High Glycemic Index Diets Linked to CVD and Mortality – TCTMD
Collaborative statement on mHealth in Arrhythmia Management: Digital Medical Tools for Heart Rhythm Professionals
25 Feb, 2021 | 08:25h | UTC
RCT: Hypothermic machine perfusion in liver transplantation
25 Feb, 2021 | 08:44h | UTCHypothermic Machine Perfusion in Liver Transplantation — A Randomized Trial – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Cold Perfusion Cuts Liver Transplant Complications – MedPage Today
Meta-analysis: Postoperative analgesic effectiveness of quadratus lumborum block for cesarean delivery under spinal anesthesia
25 Feb, 2021 | 08:31h | UTC
Commentary on Twitter
This infographic in @_Anesthesiology on the article Postoperative Analgesic
Effectiveness of Quadratus Lumborum Block for Cesarean Delivery under Spinal Anesthesia: #SystematicReview & Meta-analysis is great!#OBAneshttps://t.co/hTy1xSbLnP pic.twitter.com/x4r45ERHr6— Emily Sharpe, MD, FASA (@emilysharpe) January 7, 2021