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RCT | Sublingual microcirculatory assessment fails to reduce 30-day mortality in shock patients

15 Jun, 2023 | 15:00h | UTC

Direct assessment of microcirculation in shock: a randomized-controlled multicenter study – Intensive Care Medicine

 

Commentary on Twitter

 

SR | Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes

15 Jun, 2023 | 14:57h | UTC

Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes – Cochrane Library

 

M-A | Influencing factors of medication adherence in schizophrenic patients

15 Jun, 2023 | 14:56h | UTC

Influencing factors of medication adherence in schizophrenic patients: a meta-analysis – Schizophrenia

 

RCT | Nalbuphine reduces cough in idiopathic pulmonary fibrosis, despite adverse effects

15 Jun, 2023 | 14:55h | UTC

Nalbuphine Tablets for Cough in Patients with Idiopathic Pulmonary Fibrosis – NEJM Evidence

 

Cohort Study | Weight change and risk of obesity-related complications

15 Jun, 2023 | 14:53h | UTC

Weight change and risk of obesity-related complications: A retrospective population-based cohort study of a UK primary care database – Diabetes, Obesity and Metabolism

 

Commentary from the author on Twitter

 

M-A | Comparing non-invasive tests, histology for predicting non-alcoholic fatty liver outcomes

15 Jun, 2023 | 14:50h | UTC

Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis – The Lancet Gastroenterology & Hepatology

 

Review | Candidate biomarkers in psychiatric disorders

15 Jun, 2023 | 14:52h | UTC

Candidate biomarkers in psychiatric disorders: state of the field – World Psychiatry

 

Review | Contribution of wastewater to antimicrobial resistance

15 Jun, 2023 | 14:49h | UTC

Contribution of wastewater to Antimicrobial Resistance- A Review article – Journal of Global Antimicrobial Resistance

Related studies on surveillance of wastewater:

Use of Wastewater for Mpox Outbreak Surveillance in California – New England Journal of Medicine

Wastewater network infrastructure in public health: Applications and learnings from the COVID-19 pandemic – PLOS Global Public Health

Opinion: Wastewater analysis can be a powerful public health tool—if it’s done sensibly.

CDC unveils its latest weapon in Covid-19 detection: wastewater.

CDC Report: Using Wastewater Surveillance Data to Support the COVID-19 Response — United States, 2020–2021.

Rapid, large-scale wastewater surveillance and automated reporting system enabled early detection of nearly 85% of COVID-19 cases on a University campus.

[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.

Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME

Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT

Sewage sleuths helped an Arizona town beat back Covid-19. For wastewater epidemiology, that’s just the start – STAT

The myriad ways sewage surveillance is helping fight COVID around the world – Nature

Testing sewage can give school districts, campuses and businesses a heads-up on the spread of COVID-19 – The Conversation

It’s time to begin a national wastewater testing program for Covid-19 – STAT

Coronavirus: Testing sewage an ‘easy win’ – BBC

Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – high sensitivity, but unable to distinguish new infectious cases from persistent convalescent shedding.

 

M-A | Biosimilar and reference biologics in rheumatoid arthritis show equivalent results

15 Jun, 2023 | 14:47h | UTC

Therapeutic Equivalence of Biosimilar and Reference Biologic Drugs in Rheumatoid Arthritis: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary: Adalimumab, Etanercept, Infliximab Biosimilars Show Clinically Equivalence to Biologics in RA – HCP Live

 

Cohort Study | 63.1% of uncomplicated appendicitis in children successfully treated non-operatively at 1 year

15 Jun, 2023 | 14:45h | UTC

Outcomes 1 year after non-operative management of uncomplicated appendicitis in children: Children with AppendicitiS during the CoronAvirus panDEmic (CASCADE) study – BJS Open

 

Commentary on Twitter

 

Imaging features of the postoperative spine: a guide to basic understanding of spine surgical procedures

15 Jun, 2023 | 14:43h | UTC

Imaging features of the postoperative spine: a guide to basic understanding of spine surgical procedures – Insights into Imaging

 

Review | Fluid therapy for critically ill adults with sepsis

14 Jun, 2023 | 14:51h | UTC

Fluid Therapy for Critically Ill Adults With Sepsis: A Review – JAMA (free for a limited period)

Audio clinical review: Fluid Therapy for Critically Ill Adults With Sepsis – JAMA

 

Perspective | Inside the nascent industry of AI-designed drugs

14 Jun, 2023 | 14:50h | UTC

Inside the nascent industry of AI-designed drugs – Nature (if the link is paywalled, try this one)

 

Opinion | Threats by artificial intelligence to human health and human existence

14 Jun, 2023 | 14:47h | UTC

Threats by artificial intelligence to human health and human existence – BMJ Global Health

News Release: Doctors and public health experts join calls for halt to AI R&D until it’s regulated – BMJ Newsroom

 

RCT | Ultrasonography noninferior to radiography for pediatric distal forearm fracture diagnosis

14 Jun, 2023 | 14:45h | UTC

Ultrasonography or Radiography for Suspected Pediatric Distal Forearm Fractures – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Ultrasound breaks new ground for forearm fractures in children – Griffith University

 

RCT | 0.01% atropine effective in reducing progression of myopia in children over 3 years

14 Jun, 2023 | 14:41h | UTC

Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years: A Randomized Clinical Trial – JAMA Ophthalmology

News Release: Eye drops slow nearsightedness progression in kids – Ohio State University

See also: Visual Abstract

Related:

RCT | Effect of repeated low-level red light on myopia prevention among children in China with premyopia

Efficacy of atropine for myopia control in children: A meta-analysis of randomized controlled trials – Journal of Family Medicine and Primary Care

Interventions for myopia control in children: a living systematic review and network meta‐analysis – Cochrane Library

RCT | Effect of low-concentration atropine eyedrops vs. placebo on myopia incidence in children

Crossover RCT | Spectacle lenses with highly aspherical lenslets for slowing myopia.

RCT | Effect of text messaging parents of school-aged children on outdoor time to control myopia.

RCT | Myopia control effect of repeated low-level red-light therapy in children.

RCT: Spectacle lenses with aspherical lenslets for myopia control vs. single-vision spectacle lenses.

Randomized trial: Effect of High add power, medium add power, or single-vision contact lenses on myopia progression in children

 

M-A | Postpartum care up to 1 year after pregnancy

14 Jun, 2023 | 14:39h | UTC

Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-analysis – Agency for Healthcare Research and Quality

 

SR | Management of postpartum hypertensive disorders of pregnancy

14 Jun, 2023 | 14:37h | UTC

Management of Postpartum Hypertensive Disorders of Pregnancy – Agency for Healthcare Research and Quality

 

AAP standards for levels of neonatal care: II, III, and IV

14 Jun, 2023 | 14:35h | UTC

Standards for Levels of Neonatal Care: II, III, and IV – Pediatrics

News Release: AAP sets national standards for levels of neonatal care – AAP News

Commentary: National Standards Developed for Neonatal Care – HealthDay

 

AAP Technical Report | Dispensing medications at the hospital upon discharge from an emergency department

14 Jun, 2023 | 14:33h | UTC

Dispensing Medications at the Hospital Upon Discharge From an Emergency Department – Pediatrics

News Release: Report discusses ways to improve medication adherence after emergency visit – AAP News

Commentary: Dispensing Meds in Emergency Department Likely to Improve Adherence – HealthDay

 

M-A | Preoperative IV plus oral antibiotics reduce surgical site infections in elective colorectal surgery

14 Jun, 2023 | 14:31h | UTC

Mechanical bowel preparation and antibiotics in elective colorectal surgery: network meta-analysis – BJS Open

Related:

SR | Mechanical plus oral antibiotic bowel preparation may prevent complications in elective colorectal surgery

M-A: Strategies for antibiotic administration for bowel preparation among patients undergoing elective colorectal surgery – “the addition of oral antibiotics to intravenous antibiotics was associated with a reduction in the incidence of incisional surgical site infection by more than 50%”.

Meta-Analysis: Effects of Mechanical Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery

 

Commentary on Twitter

 

RCT | Talazoparib plus enzalutamide prolongs radiographic PFS vs. enzalutamide alone in metastatic castration-resistant prostate cancer

14 Jun, 2023 | 14:29h | UTC

Talazoparib plus enzalutamide in men with first-line metastatic castration-resistant prostate cancer (TALAPRO-2): a randomised, placebo-controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)

News Release: Talazoparib Plus Enzalutamide Improves rPFS Over Placebo Plus Enzalutamide in First-Line Treatment for Patients with mCRPC – ESMO

 

RCT | Second-line treatment with Axi-cel results in increased overall survival in large B-cell lymphoma

14 Jun, 2023 | 14:25h | UTC

Survival with Axicabtagene Ciloleucel in Large B-Cell Lymphoma – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: ASCO: Axi-cel significantly improves survival in patients with early relapsed or refractory large B-cell lymphoma – University of Texas MD Anderson Cancer Center

Commentary: Axicabtagene Ciloleucel Improves Overall Survival in Patients With Relapsed or Refractory Large B-Cell Lymphoma – The ASCO Post

 

Commentary on Twitter

 

Crossover RCT | THC and Cannabidiol demonstrate potential in Tourette syndrome tic management, despite cognitive impacts

14 Jun, 2023 | 14:27h | UTC

Tetrahydrocannabinol and Cannabidiol in Tourette Syndrome – NEJM Evidence

 

RCT | Cilta-cel shows superior progression-free survival over standard care in lenalidomide-refractory multiple myeloma

14 Jun, 2023 | 14:22h | UTC

Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Findings suggest cilta-cel may be key therapeutic option for patients with multiple myeloma after first relapse – Medical College of Wisconsin

Commentary: CARTITUDE-4 Shows Benefit With Ciltacabtagene Autoleucel in Lenalidomide-Refractory Multiple Myeloma – ASCO Daily News

 

Commentary on Twitter

 

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