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Long COVID-19: A Primer for Cardiovascular Health Professionals, on Behalf of the CCS Rapid Response Team.

20 Aug, 2021 | 09:49h | UTC

Long COVID-19: A Primer for Cardiovascular Health Professionals, on Behalf of the CCS Rapid Response Team – Canadian Journal of Cardiology

Spontaneous Coronary Artery Dissection: Pitfalls of Angiographic Diagnosis and an Approach to Ambiguous Cases.

20 Aug, 2021 | 09:06h | UTC

Spontaneous Coronary Artery Dissection: Pitfalls of Angiographic Diagnosis and an Approach to Ambiguous Cases – JACC: Cardiovascular Interventions

Commentary and summary: Spontaneous Coronary Artery Dissection Diagnosis – American College of Cardiology

M-A of randomized trials: The effect of higher versus lower protein delivery in critically ill patients – “In critically ill patients, a higher daily protein delivery was not associated with any improvement in clinical or patient-centered outcomes”.

20 Aug, 2021 | 08:57h | UTC

The effect of higher versus lower protein delivery in critically ill patients: a systematic review and meta-analysis of randomized controlled trials – Critical Care

M-A: Examination of dosing of antipsychotic drugs for relapse prevention in patients with stable schizophrenia.

20 Aug, 2021 | 09:04h | UTC

Examination of Dosing of Antipsychotic Drugs for Relapse Prevention in Patients With Stable Schizophrenia: A Meta-analysis – JAMA Psychiatry (free for a limited period)

Commentaries on Twitter

Crucial literature review on optimal antipsychotic dosing for long term maintenance in #Schizophrenia.

Conclusion: Seek Goldilocks "just right"- definitely not high because of bad side effects, but not so low as to risk relapse.

Often easier said than done. https://t.co/RBBPBMzn9D

— Allen Frances (@AllenFrancesMD) August 20, 2021

Doses higher than 5mg/day risperidone equivalent are not more effective for relapse prevention than lower doses in #schizophrenia. But caution is required at the lower end of the dose-response curve where relapse risk disproportionally increases https://t.co/kQcnuRtzYU

— JAMA Psychiatry (@JAMAPsych) August 19, 2021

Heart, mind, and soul: spirituality in cardiovascular medicine.

20 Aug, 2021 | 09:06h | UTC

Heart, mind, and soul: spirituality in cardiovascular medicine – European Heart Journal

Commentary on Twitter

Have you ever thought about the impact of spirituality on cardiovascular outcomes? You’d better meditate….https://t.co/hhf4vRoLxX #cardiotwitter @ESC_Journals @escardio pic.twitter.com/GP8cdZfTP5

— EHJ Editor-in-Chief (@ehj_ed) August 19, 2021

Prescription medications for use in pregnancy – perspective from the US Food and Drug Administration.

20 Aug, 2021 | 08:55h | UTC

Prescription medications for use in pregnancy–perspective from the US Food and Drug Administration – American Journal of Obstetrics & Gynecology

Commentary on Twitter

"There are only 9 [NINE!] drugs that have ever been approved and marketed in the United States for obstetrical indications."

Pregnant individuals deserve data to help them make informed decisions. #ResearchPregnancy https://t.co/sj7dWUzKNZ

— All Source Pregnancy (@PregnancyAll) July 17, 2021

M-A: Prevalence, management and impact of chronic obstructive pulmonary disease in atrial fibrillation.

20 Aug, 2021 | 09:01h | UTC

Prevalence, management and impact of chronic obstructive pulmonary disease in atrial fibrillation: a systematic review and meta-analysis of 4,200,000 patients – European Heart Journal (link to abstract – $ for full-text)

Commentary on Twitter

AF-COMET Meta-analysis showed #COPD is common in #AF, being found in 13% of patients
📌⬆️ burden of comorbidities & worse outcomes
📌More than a two-fold ⬆️ risk of all-cause death
📌⬆️ Risk of CV death and major bleedinghttps://t.co/fLAuGkQAX1 @ESC_Journals @SchakrabartiEP pic.twitter.com/50OSfACH84

— Henry Han (@HanCardiomd) August 2, 2021

Health care for people who are incarcerated.

20 Aug, 2021 | 08:46h | UTC

Health care for people who are incarcerated – Nature Reviews Diseases Primers

Commentary on Twitter

This Comment highlights the high medical burden of individuals who are or have been in #prison or jail and discusses how to overcome barriers to #HealthCare through funding, community health systems and addressing stigma and discrimination.https://t.co/w0z0iGIKS5 pic.twitter.com/wRuAgCZ6i7

— Nature Reviews Disease Primers (@DiseasePrimers) August 19, 2021

Variations in end-of-life practices in intensive care units worldwide: a prospective observational study.

20 Aug, 2021 | 08:51h | UTC

Variations in end-of-life practices in intensive care units worldwide (Ethicus-2): a prospective observational study – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Commentary on Twitter

Limitation of life-sustaining therapies is common worldwide with regional variability. Withholding treatment is more common than withdrawing treatment. Variations in type, frequency, and timing of end-of-life decisions were observed. https://t.co/skfjazyt7x @LancetRespirMed

— Martijn A. Spruit (@pulmonary_rehab) August 9, 2021

Study finds increased risk of gastrointestinal bleeding following concomitant treatment with oral glucocorticoids in patients on non-vitamin K oral anticoagulants.

20 Aug, 2021 | 08:45h | UTC

Gastrointestinal bleeding risk following concomitant treatment with oral glucocorticoids in patients on non-vitamin K oral anticoagulants – Heart (link to abstract – $ for full-text)

Commentary on Twitter

In this @Heart_BMJ #Afib sdy @AndersHolt6 et al. found a X2 ⬆️ risk of GI bleeding w/ NOAC💊+oral glucocorticoids⚪ vs NOAC alone 💊

Authors recommend ☝️ close monitoring 👀 or other risk 🛑 mitigation when co-prescribing

📝 https://t.co/CgtgmvnD29 #CardioTwitter #cardiology pic.twitter.com/95eCOWxozK

— Copenhagen Cardiovascular Research Center (@CopCard) August 15, 2021

Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection.

20 Aug, 2021 | 08:41h | UTC

Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection – JAC-Antimicrobial Resistance

Dementia at younger ages is more prevalent than previously estimated, meta-analysis suggests.

20 Aug, 2021 | 08:53h | UTC

Dementia at Younger Ages More Prevalent Than Previously Estimated, Meta-Analysis Suggests – Psychiatric News Alert

Original study: Global Prevalence of Young-Onset Dementia: A Systematic Review and Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)

Review: Viral respiratory pathogens and lung injury.

20 Aug, 2021 | 08:43h | UTC

Viral Respiratory Pathogens and Lung Injury – Clinical Microbiology Reviews

Metrics for evaluating antibiotic use and prescribing in outpatient settings.

20 Aug, 2021 | 08:40h | UTC

Metrics for evaluating antibiotic use and prescribing in outpatient settings – JAC-Antimicrobial Resistance

Cohort study: Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers.

20 Aug, 2021 | 08:39h | UTC

Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers: an international cohort study – American Journal of Obstetrics and Gynecology

Commentary on Twitter

For #BRCA1 mutation carriers, longer duration of oral contraceptive use (>10 yr) is associated with a greater reduction in #OvarianCancer risk, and the protection is long term. https://t.co/HrrutgaYKX

— Anna Chichura, MD (@AnnaChichuraMD) July 3, 2021

IDSA response to plan for supplemental vaccine doses for vaccinated individuals.

19 Aug, 2021 | 09:02h | UTC

Response to Plan for Supplemental Vaccine Doses for Vaccinated Individuals – Infectious Diseases Society of America

Viewpoint: Confronting the Delta variant of SARS-CoV-2.

19 Aug, 2021 | 09:03h | UTC

Confronting the Delta Variant of SARS-CoV-2, Summer 2021 – JAMA

Studies: COVID vaccine protection waning against infection but not hospitalization.

19 Aug, 2021 | 09:05h | UTC

Studies: COVID vaccine protection waning against infection but not hospitalization – CIDRAP

Study 1: Sustained Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Associated Hospitalizations Among Adults — United States, March–July 2021 – CDC Morbidity and Mortality Weekly Report

Study 2: Effectiveness of Pfizer-BioNTech and Moderna Vaccines in Preventing SARS-CoV-2 Infection Among Nursing Home Residents Before and During Widespread Circulation of the SARS-CoV-2 B.1.617.2 (Delta) Variant — National Healthcare Safety Network, March 1–August 1, 2021 – CDC Morbidity and Mortality Weekly Report

Study 3: New COVID-19 Cases and Hospitalizations Among Adults, by Vaccination Status — New York, May 3–July 25, 2021 – CDC Morbidity and Mortality Weekly Report

Commentary on Twitter (thread – click for more)

Very excited to share our most recent publication about #CovidVaccine effectiveness, just published today by the IVY network. Especially relevant in light of today’s news about #boosters (spoiler – I’m skeptical about the need for boosters for all). 🧵https://t.co/GbAxgzpo7R

— Nida Qadir, MD (@NidaQadirMD) August 18, 2021

NIH study shows no significant benefit of convalescent plasma for COVID-19 outpatients with early symptoms.

19 Aug, 2021 | 09:06h | UTC

NIH study shows no significant benefit of convalescent plasma for COVID-19 outpatients with early symptoms – NIH News Releases

Original study: Early Convalescent Plasma for High-Risk Outpatients with Covid-19 – New England Journal of Medicine

Commentary on Twitter

Convalescent plasma did not prevent disease progression in patients seen in EDs within 7 days after the onset #COVID19 symptoms. https://t.co/9gmIK3ntKH #IDTwitter pic.twitter.com/sirzn1uGL0

— NEJM (@NEJM) August 18, 2021

Vaccine stockpiling by nations could lead to increase in COVID-19 cases, novel variant emergence.

19 Aug, 2021 | 08:58h | UTC

Vaccine nationalism and the dynamics and control of SARS-CoV-2 – Science

Commentary: Vaccine stockpiling by nations could lead to increase in COVID-19 cases, novel variant emergence – Princeton University

Commentary on Twitter

Published at @sciencemagazine, a new @PrincetonEnviro study shows that stockpiling driven by vaccine 'nationalism' could increase #COVID19 cases and the potential emergence of novel variants, stressing the importance of rapid global vaccine equity. https://t.co/ziN5fX0u2X

— Princeton University (@Princeton) August 18, 2021

Hemophagocytic lymphohistiocytosis secondary to COVID-19: a case series.

19 Aug, 2021 | 08:57h | UTC

Haemophagocytic lymphohistiocytosis secondary to COVID-19: a case series – The Lancet Rheumatology

U.S. officials’ decision on Covid-19 booster shots baffles — and upsets — some scientists.

19 Aug, 2021 | 09:00h | UTC

U.S. officials’ decision on Covid-19 booster shots baffles — and upsets — some scientists – STAT

Commentary on Twitter

Scientists I spoke to today had a lot of questions about the administration's decision to start giving Americans 3rd doses of the mRNA vaccines next month. “I’m not sure we had enough [data] to pull the trigger right now," one said. https://t.co/eHUndOrQL4

— Helen Branswell 🇨🇦 (@HelenBranswell) August 18, 2021