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Registry Study: Determinants of outcomes following surgery for type A acute aortic dissection.

11 Jan, 2022 | 02:12h | UTC

Determinants of outcomes following surgery for type A acute aortic dissection: the UK National Adult Cardiac Surgical Audit – European Heart Journal

Editorial: Acute type A aortic dissection reconsidered: it’s all about the location of the primary entry tear and the presence or absence of malperfusion

 

Commentary on Twitter

 

Review | Newer generation antidepressants and withdrawal effects: reconsidering the role of antidepressants and helping patients to stop.

11 Jan, 2022 | 02:16h | UTC

Newer generation antidepressants and withdrawal effects: reconsidering the role of antidepressants and helping patients to stop – Drug and Therapeutics Bulletin

 

Commentary from the author on Twitter (thread – click for more)

 

RCT: Early exercise (1 week after surgery) may be safe after breast augmentation.

11 Jan, 2022 | 02:14h | UTC

Exercise after Breast Augmentation: A Randomized Controlled Trial – Plastic and Reconstructive Surgery

Commentary: Exercise Soon After Breast Plastic Surgery Is Safe, Healthy – HealthDay

 

RCT: In children with sickle cell anemia, hydroxyurea in moderate doses (20 mg/kg per day) is not better than low doses (10 mg/kg per day) for primary stroke prevention.

11 Jan, 2022 | 02:10h | UTC

Hydroxyurea for primary stroke prevention in children with sickle cell anaemia in Nigeria (SPRING): a double-blind, multicentre, randomised, phase 3 trial – The Lancet Haematology (link to abstract – $ for full-text)

 

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9 Jan, 2022 | 01:15h | UTC

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Cohort Study: Ciprofloxacin exposure during pregnancy was not associated with miscarriage or major malformations in a nationwide study from Denmark.

11 Jan, 2022 | 02:08h | UTC

Ciprofloxacin exposure and adverse pregnancy outcomes: a Danish nationwide cohort study – BJOG (link to abstract – $ for full-text)

 

Cohort study: Among health care workers previously vaccinated with 2 doses of the Pfizer-BioNTech vaccine, receiving a third dose was associated with reduced risk of SARS-CoV-2 infection.

11 Jan, 2022 | 01:35h | UTC

Association of a Third Dose of BNT162b2 Vaccine With Incidence of SARS-CoV-2 Infection Among Health Care Workers in Israel – JAMA

Editorial: Booster Vaccination to Reduce SARS-CoV-2 Transmission and Infection – JAMA

 

Covid-19’s Devastating Effect on Tuberculosis Care — A Path to Recovery.

11 Jan, 2022 | 01:33h | UTC

Covid-19’s Devastating Effect on Tuberculosis Care — A Path to Recovery – New England Journal of Medicine

 

Commentary on Twitter

 

Review: Rapid diagnostic testing for SARS-CoV-2.

11 Jan, 2022 | 01:34h | UTC

Rapid Diagnostic Testing for SARS-CoV-2 – New England Journal of Medicine

 

[Preprint] Lab study shows Omicron infection enhances neutralizing immunity against the Delta variant.

11 Jan, 2022 | 01:29h | UTC

Omicron infection enhances neutralizing immunity against the Delta variant – medRxiv

 

Study shows Covid-19 vaccination is associated with a smaller reduction in transmission of the delta variant compared with the alpha variant.

11 Jan, 2022 | 01:31h | UTC

Effect of Covid-19 Vaccination on Transmission of Alpha and Delta Variants – New England Journal of Medicine

 

Commentary on Twitter

 

Clinical Practice Guideline Summary: Recommended Drugs and Biologics in Adult Patients with COVID-19.

11 Jan, 2022 | 01:26h | UTC

Clinical Practice Guideline Summary: Recommended Drugs and Biologics in Adult Patients with COVID-19 – Covid Advisory for Ontario

 

Commentary on Twitter

 

M-A: Fatigue and cognitive impairment in Post-COVID-19 Syndrome.

11 Jan, 2022 | 01:28h | UTC

Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis – Brain, Behavior, and Immunity

 

Covid-19: An urgent call for global “vaccines-plus” action.

11 Jan, 2022 | 01:22h | UTC

Covid-19: An urgent call for global “vaccines-plus” action – The BMJ

 

CDC Report: COVID-19 vaccine safety in children aged 5–11 Years.

9 Jan, 2022 | 01:09h | UTC

COVID-19 Vaccine Safety in Children Aged 5–11 Years — United States, November 3–December 19, 2021 – CDC Morbidity and Mortality Weekly Report

Commentary: COVID-19 vaccine appears safe in children aged 5–11 Years – News Medical

 

Commentary on Twitter

 

New CDC Guidance shortens isolation and quarantine period for Covid-19; patients that tested positive should isolate for 5 days and, if asymptomatic after this period, can leave isolation if they can continue to mask for 5 days to minimize the risk of infecting others.

9 Jan, 2022 | 01:13h | UTC

CDC Updates and Shortens Recommended Isolation and Quarantine Period for General Population – Centers for Disease Control and Prevention

See also: Quarantine and Isolation – Centers for Disease Control and Prevention

Commentaries:

Facing criticism, CDC updates Covid-19 isolation recommendations with guidance on testing – CNN

CDC posts rationale for shorter isolation, quarantine – Associated Press

Covid-19: CDC shortens isolation period as US cases hit record high – The BMJ

Shortened CDC COVID isolation guide draws sharply mixed reviews – CIDRAP

New CDC isolation guidelines raise concerns among health experts – NPR

CDC Reduces Recommended Isolation Time for People With COVID-19 – HealthDay

COVID isolation and quarantine period for general population shortened by CDC – News Medical

CDC shortens recommended Covid-19 isolation and quarantine time – CNN

CDC cuts the recommended isolation and quarantine periods for coronavirus infections – NPR

US officials recommend shorter COVID isolation, quarantine – Associated Press

See new recommendations from other countries:

France cuts isolation times and plans crackdown on unvaccinated amid record surge in Covid cases – CNN

Covid: Self-isolation cut from 10 days to seven with negative tests – BBC

 

Omicron’s feeble attack on the lungs could make it less dangerous.

11 Jan, 2022 | 01:23h | UTC

Omicron’s feeble attack on the lungs could make it less dangerous – Nature

 

CDC Study: A test to stay strategy (allowing close contacts with masked COVID-19 exposures to remain in school) was very efficacious in preventing further school spread and allowed children to stay in the classroom as an alternative to home quarantine.

9 Jan, 2022 | 01:07h | UTC

Evaluation of Test to Stay Strategy on Secondary and Tertiary Transmission of SARS-CoV-2 in K–12 Schools — Lake County, Illinois, August 9–October 29, 2021 – CDC Morbidity and Mortality Weekly Report

Related CDC Study: Evaluation of a Test to Stay Strategy in Transitional Kindergarten Through Grade 12 Schools — Los Angeles County, California, August 16–October 31, 2021 – CDC Morbidity and Mortality Weekly Report

Related CDC Guidance:

What You Should Know About COVID-19 Testing in Schools – Centers for Disease Control and Prevention

Science Brief: Transmission of SARS-CoV-2 in K-12 Schools and Early Care and Education Programs – Updated – Centers for Disease Control and Prevention

Commentary: ‘Test-to-stay’ works to keep students in school safely, CDC director says – CNN

Related:

Instead of quarantine for Covid-exposed students, some schools are trying test-to-stay.

Cluster RCT: Daily contact testing of school-based contacts was non-inferior to self-isolation for control of COVID-19 transmission.

Kids are losing school days to quarantines. Here’s a way to keep them in classrooms – “Test-to-stay could dramatically reduce close contact quarantines”.

Opinion | Data from routine Covid testing can help schools stay open this year.

 

Commentary on Twitter

 

Diagnostics for COVID-19: moving from pandemic response to control.

8 Jan, 2022 | 23:33h | UTC

Diagnostics for COVID-19: moving from pandemic response to control – The Lancet

 

Commentary on Twitter

 

[Preprint] Among individuals with prior SARS-CoV-2 infection in Brazil, vaccine effectiveness against hospitalization or death after vaccine series completion was 81.3% for CoronaVac, 89.9% for AstraZeneca, 57.7% for J&J, and 89.7% for Pfizer.

8 Jan, 2022 | 23:26h | UTC

Effectiveness of CoronaVac, ChAdOx1, BNT162b2 and Ad26.COV2.S among – medRxiv

 

[In Portuguese] Commentary from one of the authors on Twitter (thread – click for more)

 

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

9 Jan, 2022 | 01:05h | UTC

Risk of myocarditis following sequential COVID-19 vaccinations by age and sex – medRxiv

Commentary: An evaluation of the association between COVID vaccination and myocarditis in 42 million people aged 13 or older – News Medical

Note: this study is an updated analysis of a recent study published in Nature Medicine; see below:

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

 

Compared with previous waves, the Omicron wave in South Africa was associated with fewer hospitalizations and decreased severity and mortality.

8 Jan, 2022 | 23:23h | UTC

Characteristics and Outcomes of Hospitalized Patients in South Africa During the COVID-19 Omicron Wave Compared With Previous Waves – JAMA

 

[Preprint] RCT: In symptomatic adults above 18 years positive for SARS-CoV-2, early outpatient treatment with high-titer convalescent plasma significantly reduced hospitalizations.

8 Jan, 2022 | 23:28h | UTC

Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent Plasma – medRxiv

News release: Early Use of Convalescent Plasma May Help Outpatients with COVID-19 Avoid Hospitalization – Johns Hopkins Medicine

Commentary: Convalescent plasma shows renewed promise for COVID-19 in outpatient trial – Science

 

Guideline: ADA 2022 Standards of Medical Care in Diabetes.

24 Dec, 2021 | 13:38h | UTC

Guideline Homepage: ADA 2022 Standards of Medical Care in Diabetes – American Diabetes Association

Introduction: Standards of Medical Care in Diabetes—2022

Summary of Revisions: Standards of Medical Care in Diabetes—2022

Standards of Medical Care in Diabetes—2022 Guideline Abridged for Primary Care Providers

Video Summary: Standards of Care in Diabetes – 2022

  1. Improving Care and Promoting Health in Populations
  2. Classification and Diagnosis of Diabetes 
  3. Prevention or Delay of Type 2 Diabetes and Associated Comorbidities
  4. Comprehensive Medical Evaluation and Assessment of Comorbidities
  5. Facilitating Behavior Change and Well-being to Improve Health Outcomes
  6. Glycemic Targets
  7. Diabetes Technology
  8. Obesity and Weight Management for the Prevention and Treatment of Type 2 Diabetes
  9. Pharmacologic Approaches to Glycemic Treatment
  10. Cardiovascular Disease and Risk Management
  11. Chronic Kidney Disease and Risk Management
  12. Retinopathy, Neuropathy, and Foot Care
  13. Older Adults
  14. Children and Adolescents
  15. Management of Diabetes in Pregnancy
  16. Diabetes Care in the Hospital
  17. Diabetes Advocacy

 

Commentaries on Twitter

 

[Preprint] Study showed reduced clinical severity of Covid-19 patients admitted to hospitals in Gauteng, South Africa, during the Omicron-dominant fourth wave – “any combination of a less-virulent virus, comorbidities, high immunity from prior infection(s) or vaccination may be important contributors to this clinical presentation”.

8 Jan, 2022 | 23:24h | UTC

Clinical Severity of COVID-19 Patients Admitted to Hospitals in Gauteng, South Africa During the Omicron-Dominant Fourth Wave – SSRN/Preprints with The Lancet

Commentary: SARS-CoV-2 omicron variant may be less severe than the delta variant – News Medical

 

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