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Phase 2 RCT: Adjunctive ketamine with relapse prevention–based psychological therapy shows promise for the treatment of alcohol use disorder.

12 Jan, 2022 | 08:42h | UTC

Adjunctive Ketamine With Relapse Prevention–Based Psychological Therapy in the Treatment of Alcohol Use Disorder – The American Journal of Psychiatry (link to abstract – $ for full-text)

Commentary: People With AUD May Benefit From Combination of Ketamine, Mindfulness Therapy – Psychiatric News Alert

 


RCT: Among patients with short bulbar urethral strictures, those submitted to transecting excision and primary anastomosis (tEPA) reported more penile complications compared to patients submitted to buccal mucosa grafting (BMG).

12 Jan, 2022 | 08:39h | UTC

To Transect or Not Transect: Results from the Scandinavian Urethroplasty Study, A Multicentre Randomised Study of Bulbar Urethroplasty Comparing Excision and Primary Anastomosis Versus Buccal Mucosal Grafting – European Urology

 

Commentary on Twitter

 


Cohort Study: Higher consumption of olive oil linked to lower risk of cardiovascular, cancer, and all-cause mortality.

12 Jan, 2022 | 08:41h | UTC

Consumption of Olive Oil and Risk of Total and Cause-Specific Mortality Among U.S. Adults – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries:

Higher olive oil intake associated with lower risk of CVD mortality – American College of Cardiology

Higher Olive Oil Intake May Be Associated With Lower Risk of CVD Mortality – American College of Cardiology

 


Systematic Review: Antecolic vs. retrocolic reconstruction after partial pancreaticoduodenectomy.

12 Jan, 2022 | 08:38h | UTC

Antecolic versus retrocolic reconstruction after partial pancreaticoduodenectomy – Cochrane Library

 


Consequences of a diagnostic label: A systematic scoping review and thematic framework.

12 Jan, 2022 | 08:37h | UTC

Consequences of a Diagnostic Label: A Systematic Scoping Review and Thematic Framework – Frontiers in Public Health

 


RCT: Interferon-alpha vs. Hydroxyurea in Polycythemia Vera and Essential Thrombocythemia.

12 Jan, 2022 | 08:35h | UTC

A Randomized, Phase 3, Trial of Interferon-α versus Hydroxyurea in Polycythemia Vera and Essential Thrombocythemia – Blood

 


Review: Management of coagulopathy in bleeding patients.

12 Jan, 2022 | 08:34h | UTC

Management of Coagulopathy in Bleeding Patients – Journal of Clinical Medicine

 


Clinical Guideline: Acute-on-chronic liver failure.

11 Jan, 2022 | 02:43h | UTC

Acute-on-Chronic Liver Failure Clinical Guidelines – American Journal of Gastroenterology

Related: Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU

 

Commentary on Twitter

 


Perspective: What Sci-Hub’s latest court battle means for research.

12 Jan, 2022 | 08:32h | UTC

What Sci-Hub’s latest court battle means for research – Nature

 


European Guidelines on non–muscle-invasive bladder cancer (Ta, T1, and Carcinoma in Situ).

12 Jan, 2022 | 08:32h | UTC

European Association of Urology Guidelines on Non–muscle-invasive Bladder Cancer (Ta, T1, and Carcinoma in Situ) – European Urology

 


AHA Scientific Statement: Comprehensive management of cardiovascular risk factors for adults with Type 2 Diabetes.

11 Jan, 2022 | 02:40h | UTC

Comprehensive Management of Cardiovascular Risk Factors for Adults With Type 2 Diabetes: A Scientific Statement From the American Heart Association – Circulation

News Release: Fewer than 1 in 5 adults with Type 2 diabetes in the U.S. are meeting optimal heart health targets – American Heart Association

 


Best Practice Recommendations: Management of adults and children receiving CAR T-cell therapy.

12 Jan, 2022 | 08:31h | UTC

Management of Adults and Children receiving CAR T-cell therapy: 2021 Best Practice Recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) and the European Haematology Association (EHA) – Annals of Oncology

 


Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019.

11 Jan, 2022 | 02:38h | UTC

Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019 – The Lancet Public Health

News Release: Global dementia cases set to triple by 2050 unless countries address risk factors – The Lancet

Commentaries:

Forecasting the prevalence of dementia – The Lancet Public Health

Dementia cases expected to almost triple across the world by 2050 – BBC

Number of adults with dementia to exceed 150m by 2050, study finds – The Guardian

 

Commentary on Twitter (thread – click for more)

 


In 1st, US surgeons transplant pig heart into human patient.

11 Jan, 2022 | 02:34h | UTC

In 1st, US surgeons transplant pig heart into human patient – Associated Press

 


Position Statement: Prehospital surgical airway management.

11 Jan, 2022 | 02:39h | UTC

Prehospital Surgical Airway Management: An NAEMSP Position Statement and Resource Document – Prehospital Emergency Care

 


Special Issue: Peri‐operative and critical care management of the brain ‐ current evidence.

11 Jan, 2022 | 02:36h | UTC

Homepage: Special Issue:Peri‐operative and critical care management of the brain ‐ current evidence – Anaesthesia

Editorials:

In search of the perfect outcome in neuroanaesthesia and neurocritical care

Anaesthesia and the older brain: what should we do?

Review Articles:

Implications of nocebo in anaesthesia care

Chronic subdural haematoma: the role of peri-operative medicine in a common form of reversible brain injury

Acute peri-operative neurocognitive disorders: a narrative review

Pragmatic sedation strategies to prevent secondary brain injury in low-resource settings

Delirium and COVID-19: a narrative review of emerging evidence

Anaesthesia for mechanical thrombectomy: a narrative review

Clinical applications of point-of-care ultrasound in brain injury: a narrative review

Management of status epilepticus: a narrative review

Evidence-based strategies to reduce the incidence of postoperative delirium: a narrative review

Management of traumatic brain injury: a narrative review of current evidence

Peri-operative neurological monitoring with electroencephalography and cerebral oximetry: a narrative review

Peri-operative management of patients with Parkinson’s disease

 


Medical Decisions: Some are Easy and Some Not So Much.

11 Jan, 2022 | 02:31h | UTC

Medical Decisions: Some are Easy and Some Not So Much – Stop and Think blog, by John Mandrola

 

Commentary on Twitter

https://twitter.com/drjohnm/status/1480289256518176770

 


Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019.

11 Jan, 2022 | 02:30h | UTC

Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019 – JAMA Oncology

News Release: Cancer deaths rose to 10 million worldwide in 2019: Recent trends also highlight global disparities in cancer burden – Institute for Health Metrics and Evaluation

 


RCT: In premenopausal women with breast cancer, gonadotropin-releasing hormone analogs may preserve ovarian function against chemotherapy-induced gonadotoxic effects.

11 Jan, 2022 | 02:26h | UTC

Effects of Gonadotropin-Releasing Hormone Analogs on Ovarian Function Against Chemotherapy-Induced Gonadotoxic Effects in Premenopausal Women With Breast Cancer in China: A Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


RCT: In patients presenting with metastatic breast cancer, early locoregional therapy for the primary site did not improve survival or quality of life.

11 Jan, 2022 | 02:29h | UTC

Early Local Therapy for the Primary Site in De Novo Stage IV Breast Cancer: Results of a Randomized Clinical Trial (EA2108) – Journal of Clinical Oncology (link to abstract – $ for full-text)

 


Systematic Review: First-generation cephalosporins for the treatment of complicated upper urinary tract infection in adults.

11 Jan, 2022 | 02:23h | UTC

First-generation cephalosporins for the treatment of complicated upper urinary tract infection in adults: A systematic literature review – International Journal of Infectious Diseases

 

Commentary on Twitter

 


Systematic Review: The effectiveness and safety of treatments for recurrent vulvovaginal candidiasis.

11 Jan, 2022 | 02:24h | UTC

Treatment for recurrent vulvovaginal candidiasis (thrush) – Cochrane Library

Summary: The effectiveness and safety of treatments for recurrent vulvovaginal candidiasis (thrush) – Cochrane Library

 


Review: New aspects in the management of hypertension in patients with chronic kidney disease not on renal replacement therapy.

11 Jan, 2022 | 02:22h | UTC

New Aspects in the Management of Hypertension in Patients with Chronic Kidney Disease not on Renal Replacement Therapy – High Blood Pressure & Cardiovascular Prevention

Related: RCT: In patients with advanced chronic kidney disease and poorly controlled hypertension, Chlortalidone had a significant impact in blood-pressure control (−11.0 mm Hg vs. −0.5 mm Hg in the placebo group).

 


The ‘Ten Commandments’ of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.

11 Jan, 2022 | 02:20h | UTC

The ‘Ten Commandments’ of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure – European Heart Journal

Original Guideline: #ESCCongress – 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure – SGLT2 inhibitors are now recommended for patients with heart failure with reduced ejection fraction regardless of the presence of diabetes.

Related:

NICE Guideline | Acute heart failure: diagnosis and management.

The ‘ten commandments’ for the 2021 ESC Guidelines on CVD prevention.

 


M-A: Fecal immunochemical test to triage patients with possible colorectal cancer symptoms.

11 Jan, 2022 | 02:18h | UTC

Faecal immunochemical test to triage patients with possible colorectal cancer symptoms: meta-analysis – British Journal of Surgery

Commentary: Guest Plain English summary: Worried about symptoms of bowel cancer? A simple stool test may help. – Cutting Edge

 

Commentary on Twitter

 


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