All Posts
Takotsubo Syndrome: A review of presentation, diagnosis and management.
2 Feb, 2022 | 08:25h | UTCRelated:
International Expert Consensus Document on Takotsubo Syndrome
International Registry: 16.6% of Patients with Takotsubo Syndrome Have Underlying Malignancy
Systematic Review: Long-Term Prognosis and Outcome Predictors in Takotsubo Syndrome
Cohort Study: Hospital Readmission Following Takotsubo Syndrome
RCT: 2 L polyethylene glycol plus ascorbic acid may provide similar efficacy and better tolerability as 4 L polyethylene glycol for bowel cleansing in elderly patients aged 60–79.
2 Feb, 2022 | 08:29h | UTCComparison of 2 L Polyethylene Glycol Plus Ascorbic Acid and 4 L Polyethylene Glycol in Elderly Patients Aged 60–79: A Prospective Randomized Study – Digestive Diseases and Sciences (link to abstract – $ for full-text)
Related Guidelines:
Bowel preparation before colonoscopy – Gastrointestinal Endoscopy
DIC in Pregnancy: Pathophysiology, clinical characteristics, diagnostic scores, and treatments.
2 Feb, 2022 | 08:27h | UTC
RCT: Efficacy and safety of Risankizumab for active psoriatic arthritis.
2 Feb, 2022 | 08:23h | UTC
Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicenter pooled analysis of 5161 patients.
2 Feb, 2022 | 08:22h | UTC
Short Review | Hypersensitivity reactions to vaccines in children: from measles to SARS-CoV-2.
2 Feb, 2022 | 08:13h | UTCCommentary: Vaccine hypersensitivity in children – News Medical
M-A: Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis.
2 Feb, 2022 | 08:20h | UTCEfficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
M-A: Birth outcomes of neonates exposed to marijuana in utero.
2 Feb, 2022 | 08:19h | UTCInvited commentary: Reexamining Risks of Prenatal Cannabis Use—Mounting Evidence and a Call to Action – JAMA Network Open
Commentary on Twitter
This systematic review and meta-analysis found that prenatal marijuana exposure is associated with increases in many adverse neonatal outcomes, including lower birth weight and preterm delivery. @MarchandSurgery @tmcaznews https://t.co/qvWOWu4Dkc
— JAMA Network Open (@JAMANetworkOpen) January 27, 2022
Review: Advance care planning and goals of care discussions in advanced liver disease.
2 Feb, 2022 | 08:17h | UTC
Review: Diagnosis and Management of Multiple Myeloma.
2 Feb, 2022 | 08:11h | UTCDiagnosis and Management of Multiple Myeloma: A Review – JAMA (free for a limited period)
Audio Clinical Review: Diagnosis and Management of Multiple Myeloma – JAMA
Review: Eosinophils and eosinophilic immune dysfunction in health and disease.
2 Feb, 2022 | 08:15h | UTCEosinophils and eosinophilic immune dysfunction in health and disease – European Respiratory Review
Systematic Review: Non-operative treatment for lumbar spinal stenosis with neurogenic claudication.
2 Feb, 2022 | 08:08h | UTC
Review: Prevention of atherosclerosis from childhood.
2 Feb, 2022 | 08:12h | UTCPrevention of atherosclerosis from childhood – Nature Reviews Cardiology (if the link is paywalled, try this one)
Study Commentary | Diagnostic labels in mental illness: helpful or harmful?
2 Feb, 2022 | 08:10h | UTCDiagnostic labels: helpful or harmful? – The Mental Elf
Related: Consequences of a diagnostic label: A systematic scoping review and thematic framework.
Observational study suggests Ceftaroline has comparable efficacy vs. Daptomycin for the treatment of Methicillin-Resistant Staphylococcus aureus bloodstream infection.
2 Feb, 2022 | 08:07h | UTC
Commentary on Twitter
New in OFID: A multicenter retrospective observational cohort study found no difference in treatment failure or mortality between MRSA bloodstream infections treated with ceftaroline or daptomycin.
📄: https://t.co/3QB5JXd8s5@PaulSaxMD @DrJLi @FungalDoc @IDpharmresearch pic.twitter.com/zNa9XRWP8F
— IDSA (@IDSAInfo) December 29, 2021
WHO Recommendations: Reducing the risk of cognitive decline and dementia.
1 Feb, 2022 | 09:50h | UTCReducing the Risk of Cognitive Decline and Dementia: WHO Recommendations – Frontiers in Neurology
Related:
New WHO toolkit promotes inclusion of people with dementia in society.
Dementia: number of people affected to triple in next 30 years – World Health Organization
SCAI SHOCK Cardiogenic Shock Classification Expert Consensus Update.
1 Feb, 2022 | 09:53h | UTCNews Release: SCAI releases updated expert consensus to SCAI SHOCK classification – Society for Cardiovascular Angiography and Interventions
Commentaries:
SCAI SHOCK: Update Refines Cardiogenic Shock Classification – TCTMD
SCAI Releases Updated Expert Consensus to SCAI SHOCK Classification – American College of Cardiology
Commentaries on Twitter
.@SCAI SHOCK stage is an indication of shock severity & comprises one component of mortality risk prediction in pts w/ CS, along w/ etiology/phenotype & other risk modifiers; a 3-axis model of risk stratification in CS has been proposed. Learn more: https://t.co/tnh2JFhHzN #JACC pic.twitter.com/yK2ye9wcd0
— JACC Journals (@JACCJournals) January 31, 2022
SCAI SHOCK Stage Classification Expert Consensus Update released today in the inaugural issue of @MyJSCAI and also in @JACCJournals. Thank you to endorsing societies @ACCinTouch @american_heart @ACEPNow @escardio @ACVCPresident @ISHLT @SCCM @STS_CTsurgery https://t.co/GHrYn5I5WO pic.twitter.com/Y0mKC0zONu
— SCAI (@SCAI) January 31, 2022
The Lancet Commission: Experts warn of the increasing overmedicalization of death, call for radical rethink of how society cares for dying people.
1 Feb, 2022 | 09:55h | UTCHomepage: Lancet Commission on the Value of Death (free registration required for all articles)
Report of the Lancet Commission on the Value of Death: bringing death back into life
The precariousness of balancing life and death
Ros Taylor: seeing palliative care as relational
Commentary on Twitter (thread – click for more)
Increasing overmedicalisation at the end of life is denying people & their families a good death.
Towards a compassionate community model: The Lancet #ValueofDeath Commission calls for a radical rethink of care for the dying & attitudes to death. https://t.co/DpJiu1tOcV pic.twitter.com/FU9MgCO1J6
— The Lancet (@TheLancet) January 31, 2022
Observational study: Pharmacist involvement in the care of critically ill patients may reduce resource utilization, adverse drug events, and medical costs.
1 Feb, 2022 | 09:47h | UTC
Commentary from the author on Twitter (thread – click for more)
PHARM-CRIT Study
👩🔬 215 ICU PharmDs at 85 centers
💊55,926 accepted interventions on 27,681 patients over 3,148 shifts
💵$23,404,089 cost avoidance; monetary benefit-to-cost ratio for ICU pharmacists $3.3:1 – $9.6:1@SCCM_CPP @SCCM #TwitteRx #PharmICU https://t.co/Hv4jPwU6eb— Megan Rech, PharmD, MS (@MeganARech) December 16, 2021
RCT: Impact of portable normothermic blood-based machine perfusion on outcomes of liver transplant.
1 Feb, 2022 | 08:58h | UTCCommentaries:
Normothermic Machine Perfusion Improves Outcomes in Liver Transplant Recipients – Physician’s Weekly
Machine Perfusion Cuts Early Graft Dysfunction in Liver Transplantation – MedPage Today (free registration required)
Related:
RCT: Hypothermic machine perfusion in liver transplantation
Transplantation of Discarded Livers Following Viability Testing with Normothermic Machine Perfusion
Commentaries on Twitter
Study found portable normothermic oxygenated machine perfusion of donor liver grafts resulted in improved outcomes of liver transplantation and in more livers being transplanted. https://t.co/PZzvFriJvB pic.twitter.com/2icSfxoLDF
— JAMA Surgery (@JAMASurgery) January 5, 2022
Study found portable normothermic oxygenated machine perfusion of donor liver grafts resulted in improved outcomes of liver transplantation and in more livers being transplanted. https://t.co/TKEsTf8Htu pic.twitter.com/tg2xDGDyOS
— JAMA Surgery (@JAMASurgery) January 5, 2022
[Preprint] Study suggests SARS-CoV-2 Omicron subvariants BA.2 is even more transmissible than the original variant.
1 Feb, 2022 | 08:56h | UTCCommentaries:
Study suggests BA.2 COVID-19 subvariant more contagious – CIDRAP
‘Stealth Omicron’ spreads more than original strain: study – MedicalXpress
Commentary from the author on Twitter (thread – click for more)
New Preprint Out!
“Transmission of SARS-CoV-2 Omicron VOC subvariants BA.1 and BA.2: Evidence from Danish Households”
We investigate the secondary attack rate (SAR) in #Omicron BA.1 vs. BA.2 households in Demark, 20 December 2021 – 18 January 2022.https://t.co/F3XBH2LnW9
1/ pic.twitter.com/MwGPNYkOg8— Frederik Plesner Lyngse (@LyngseF) January 31, 2022
Does the world need an Omicron vaccine? What researchers say.
1 Feb, 2022 | 08:53h | UTCDoes the world need an Omicron vaccine? What researchers say – Nature
Consensus: Nephrotoxins and acute kidney injury.
1 Feb, 2022 | 08:46h | UTC
Will Omicron end the pandemic? Here’s what experts say.
1 Feb, 2022 | 08:54h | UTCWill Omicron end the pandemic? Here’s what experts say – Nature
Randomized trials on non-pharmaceutical interventions for COVID-19 as of August 2021: a scoping review.
1 Feb, 2022 | 08:51h | UTCRelated:
Study ranks the most effective non-pharmaceutical interventions for reducing COVID-19 spread
Effect of Non-pharmaceutical Interventions to Contain COVID-19 in China
Commentary from the author on Twitter (thread – click for more)
Our analysis of trials on NPIs for COVID-19 just published with the wonderful Julian Hirt & @PerrineJaniaud ! @BMJ_EBM @CovidEvidence https://t.co/4AIaATl4Jk
1/4 pic.twitter.com/jbd9FIF299
— Lars G. Hemkens (@LGHemkens) January 28, 2022