All Posts
IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections
12 Jun, 2023 | 13:58h | UTCRelated:
M-A | Elevated HbA1c in gestational diabetes mellitus tied to 1.7-fold rise in large for gestational age incidence
13 Jun, 2023 | 13:39h | UTC
RCT | Noninferior survival rates with hearts donated after circulatory death versus brain death
12 Jun, 2023 | 13:57h | UTCTransplantation Outcomes with Donor Hearts after Circulatory Death – New England Journal of Medicine (link to abstract – $ for full-text)
Video summary: Outcomes with Donor Hearts after Circulatory Death | NEJM
News Release: Multicenter Trial Finds Using Circulatory Death Donors is Safe and Effective for Heart Transplantation – Northwestern Medicine
Commentary: Transplantation Outcomes With Donor Hearts After Circulatory Death – American College of Cardiology
Commentary on Twitter
In a randomized trial, survival at 6 months after transplantation with hearts donated after circulatory death was noninferior to that with hearts donated after brain death. https://t.co/IymsknTqSE#cardiology pic.twitter.com/oYAS10fVJt
— NEJM (@NEJM) June 7, 2023
2ry Analysis of a RCT | Metformin linked to 41% reduction in long COVID incidence in outpatient treatment
12 Jun, 2023 | 13:55h | UTCNews Release: Study shows metformin lowers the risk of getting long COVID – University of Minnesota Medical School
Commentary on Twitter
These data not persuasive. There are 6 different arms. 3 drugs. This is not the primary endpoint. No adjustment for multiple testing.
Even USFDA would not accept these data for regulatory approval, and they are basically working for Pharma at this pthttps://t.co/FZoxo9shtG
— Vinay Prasad MD MPH (@VPrasadMDMPH) June 9, 2023
Pre-clinical Study | Taurine deficiency and aging, a correlation found in mice, monkeys, and worms
12 Jun, 2023 | 13:53h | UTCTaurine deficiency as a driver of aging – Science
Invited Commentary: Taurine linked with healthy aging – Science
News Release: Taurine May Be a Key to Longer and Healthier Life – Columbia University
Commentary on Twitter
Taurine deficiency may be a driver for aging, finds a new Science study in several animal models. The results warrant clinical trials to examine taurine’s effect on healthy lifespan in humans.
?: https://t.co/iJfI4rne7o#SciencePerspective: https://t.co/EdOKecgoqF pic.twitter.com/dekChiKRN3
— Science Magazine (@ScienceMagazine) June 8, 2023
Guidelines for reporting observational research in urology | The importance of clear reference to causality
12 Jun, 2023 | 13:50h | UTC
AHA Scientific Statement | Treatment strategies for cardiomyopathy in children
12 Jun, 2023 | 13:49h | UTCNews Releases:
Top Things to Know: Treatment Strategies for Cardiomyopathy in Children – American Heart Association
Guideline | Prevention and therapy of preterm birth
12 Jun, 2023 | 13:45h | UTCPrevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG
Review | Volume management with kidney replacement therapy in the critically ill patient
12 Jun, 2023 | 13:43h | UTC
SR | Effectiveness of anticholinergic drugs for treating people with overactive bladder syndrome
12 Jun, 2023 | 13:41h | UTC
RCT | Letermovir demonstrates noninferiority to valganciclovir for CMV prophylaxis in kidney transplantation
12 Jun, 2023 | 13:38h | UTCLetermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: A New Antiviral Option for Cytomegalovirus Prevention After Kidney Transplant – JAMA (free for a limited period)
See also: Visual Abstract
Review | Pregnancy as an early cardiovascular moment: peripartum cardiovascular health
12 Jun, 2023 | 13:36h | UTCPregnancy as an Early Cardiovascular Moment: Peripartum Cardiovascular Health – Circulation Research
Commentary on Twitter
@CircRes Alert! Compendium on Early #CVD#Pregnancy as an Early #Cardiovascular Moment: #Peripartum Cardiovascular Health https://t.co/tqOWn9AU0O
Authored by Drs. @heartdocsadiya, NA Cameron, and KJ Lindley pic.twitter.com/KlOXura8Y2
— Circulation Research (@CircRes) June 10, 2023
Review | Drivers of inappropriate antibiotic use in low- and middle-income countries
12 Jun, 2023 | 13:35h | UTC
Review | Acute dyspnea in the emergency department
12 Jun, 2023 | 13:33h | UTCAcute dyspnea in the emergency department: a clinical review – Internal and Emergency Medicine
Brief Review | Resistance to unfractionated heparin in the ICU: evaluation and management options
12 Jun, 2023 | 13:32h | UTCResistance to unfractionated heparin in the ICU: evaluation and management options – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
? Resistance to unfractionated heparin in #ICU, evaluation & management options
? monitoring UFH
? mechanisms of resistance
? how to manage UFH resistance
PS check supplement table on IV anticoagulants in ICU#FOAMcc @JerroldLevy @Dr_Cit @foamecmo
?️ https://t.co/ojQw5On5ZL pic.twitter.com/0uPQuwUmOr— Intensive Care Medicine (@yourICM) June 7, 2023
Review | Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges
12 Jun, 2023 | 13:30h | UTCPortable, wearable and implantable artificial kidney systems: needs, opportunities and challenges – Nature Reviews Nephrology (if the link is paywalled, try this one)
Cohort Study | Almost a third of bipolar disorder patients non-adherent to 20% or more of prescriptions
12 Jun, 2023 | 13:29h | UTC
Cohort Study | Pulmonary hypertension post-VTE linked to a twofold increase in long-term mortality
12 Jun, 2023 | 13:27h | UTC
Cohort Study | Prognostic model for predicting methotrexate toxicity in immune mediated inflammatory diseases
12 Jun, 2023 | 13:26h | UTCNews Release: New study reveals way to predict side-effect risk from common immune suppressant medication – University of Nottingham
Commentary: Prognostic model stratifies risk for methotrexate toxicity – ACP Internist
M-A | Clinical outcomes associated with drugs for obesity and overweight
12 Jun, 2023 | 13:24h | UTC
Review | Hemodynamic and respiratory support in pulmonary embolism
12 Jun, 2023 | 13:22h | UTC
RCT | Multivitamin supplementation may improve memory in aged adults
7 Jun, 2023 | 14:12h | UTCMultivitamin Supplementation Improves Memory in Older Adults: A Randomized Clinical Trial – The American Journal of Clinical Nutrition (link to abstract – $ for full-text)
News Releases:
Multivitamin Improves Memory in Older Adults, Study Finds – Columbia University
Related Research: Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial – Alzheimer’s & Dementia
SR | Limited evidence for vitamin and mineral supplements in delaying dementia in people with mild cognitive impairment
7 Jun, 2023 | 14:09h | UTC
Commentary on Twitter
? How does vitamin and mineral supplementation affect #cognitivefunction and progression to #dementia in people with mild cognitive impairment (MCI)?
Get the current evidence picture in this #systematicreview on @CochraneLibrary: https://t.co/YUsbjELIZq@NIH_ODS #NSHFD pic.twitter.com/hRl27Tm7op— Cochrane CAM (@CochraneCAM) May 31, 2023
Review | Reducing the carbon footprint and resource use of critical care
7 Jun, 2023 | 14:07h | UTCTowards net zero: critical care – The BMJ (free for a limited period)
Commentary on Twitter
ICUs are a considerable contributor to the carbon footprint of hospitals.
This article and #BMJInfographic present ways to reduce wastehttps://t.co/F2DPQcFnCy pic.twitter.com/bHwu9YZEgo
— The BMJ (@bmj_latest) June 3, 2023
RCT | Preoperative FOLFOX noninferior to chemoradiotherapy in locally advanced rectal cancer
7 Jun, 2023 | 14:06h | UTCPreoperative Treatment of Locally Advanced Rectal Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Related Publication: Patient-Reported Outcomes During and After Treatment for Locally Advanced Rectal Cancer in the PROSPECT Trial (Alliance N1048) – Journal of Clinical Oncology
Commentary: Radiation May Be Safely Omitted in Select Patients With Locally Advanced Rectal Cancer – The ASCO Post
Commentary on Twitter
Original Article: Preoperative Treatment of Locally Advanced Rectal Cancer (PROSPECT) https://t.co/6ubagrEzyw#ASCO23 pic.twitter.com/g2XFBkEk4T
— NEJM (@NEJM) June 5, 2023