All Posts | Links Medicus - Free Medical News & Perspective

TTMV-HPV DNA testing | Promising diagnostic and surveillance tool for HPV-linked oropharyngeal cancer

17 Jul, 2023 | 13:25h | UTC

Performance of Liquid Biopsy for Diagnosis and Surveillance of Human Papillomavirus–Associated Oropharyngeal Cancer – JAMA Otolaryngology–Head & Neck Surgery (free for a limited period)

Invited Commentary: Circulating Human Papillomavirus Tumor DNA—Ready for Prime Time? – – JAMA Otolaryngology–Head & Neck Surgery (free for a limited period)

Review | Guiding the use of invasive cardiac interventions in patients with advanced malignancies

17 Jul, 2023 | 13:23h | UTC

Invasive Cardiac Interventions in Patients With Active, Advanced Solid and Hematologic Malignancies: A Conceptual Framework: JACC: CardioOncology State-of-the-Art Review – JACC: CardioOncology

Cohort Study | Mental disorders linked to increased cardiovascular events in young patients

17 Jul, 2023 | 13:20h | UTC

Increased cardiovascular events in young patients with mental disorders: a nationwide cohort study – European Journal of Preventive Cardiology (free for a limited period)

News Release: Under 40s with mental health problems have elevated risks of heart attack and stroke – European Society of Cardiology

Brief Review | Neurological diseases in intensive care

17 Jul, 2023 | 13:19h | UTC

Neurological diseases in intensive care – Intensive Care Medicine

Commentary on Twitter

Neurological diseases in #ICU
◼️ black box of neurocritical care
🧠 heterogeneity of care
⏳ impact of early interventions on long‑term outcomes
📉 side effects of medical treatments/unexpected trial results
🔮 neuro-prognostication#FOAMcc @yourICM
🖇️ https://t.co/w3GUhQGGGs pic.twitter.com/fzkRghKHB2

— Intensive Care Medicine (@yourICM) July 12, 2023

RCT | 4-week course of subcutaneous ketamine shows efficacy in treatment-resistant depression

17 Jul, 2023 | 13:17h | UTC

Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial – British Journal of Psychiatry

News Release: Ketamine effective for treatment-resistant depression: Clinical trial – University of New South Wales

M-A | Electroconvulsive therapy may be superior to ketamine for patients with major depressive episode

RCT | Assessing low-dose ketamine’s antidepressant & antisuicidal effects in patients with treatment-resistant depression

M-A | Efficacy and safety of ketamine vs. electroconvulsive therapy among patients with major depressive episode.

Consensus Paper | Implementing strategies to prevent infections in acute-care settings

14 Jul, 2023 | 13:03h | UTC

Implementing strategies to prevent infections in acute-care settings – Infection Control & Hospital Epidemiology

News Release: New guidance for infection prevention in acute care settings – Society for Healthcare Epidemiology of America

Consensus Paper | Strategies to prevent surgical site infections in acute-care hospitals

Consensus Paper | Strategies to prevent Clostridioides difficile infections in acute-care hospitals

SHEA/IDSA/APIC Practice Recommendation: Strategies to prevent healthcare-associated infections through hand hygiene: 2022 Update – Infection Control & Hospital Epidemiology

SHEA statement on antibiotic stewardship in hospitals during public health emergencies – Infection Control & Hospital Epidemiology

Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology

Strategies to prevent central line-associated bloodstream infections in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology

Consensus Statement | Aerosol therapy in adult critically ill patients

14 Jul, 2023 | 13:01h | UTC

Aerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support – Annals of Intensive Care

M-A | First-line thiazide diuretics show reduced cardiovascular events, comparable mortality vs. other antihypertensive drugs

14 Jul, 2023 | 12:55h | UTC

First‐line diuretics versus other classes of antihypertensive drugs for hypertension – Cochrane Library

Summary: What are the benefits and harms of diuretics given as a first treatment compared to other drug classes for hypertension (high blood pressure)? – Cochrane Library

Quality Improvement Study | Improved asymptomatic bacteriuria management by reduction of unnecessary urine culture requests

14 Jul, 2023 | 12:54h | UTC

A Statewide Quality Initiative to Reduce Unnecessary Antibiotic Treatment of Asymptomatic Bacteriuria – JAMA Internal Medicine

Study: Hospital Intervention Resulted in a 45% Reduction in the Urine Cultures Ordered

Optimal Urine Culture Diagnostic Stewardship Practice—Results from an Expert Modified-Delphi Procedure – Clinical Infectious Diseases

USPSTF Recommendation Statement: Screening for Asymptomatic Bacteriuria in Adults

Cohort Study: Antibiotic Treatment of Asymptomatic Bacteriuria in Hospitalized Patients is Common, and May be Associated with Longer Duration of Hospitalization

Inappropriate Management of Asymptomatic Patients With Positive Urine Cultures: A Systematic Review and Meta-analysis – Open Forum Infectious Diseases

IDSA Guideline for the Management of Asymptomatic Bacteriuria

Commentary on Twitter

🔥🔥🔥Powerful message from our new study in @JAMAInternalMed: diagnostic stewardship (better use of diagnostic tests) was responsible for ALL the⬇️in unnecessary antibiotic use for ASB. ➕results🟰💪nudge to action. Time to👀👀upstream to improve care! https://t.co/yO4UpA6ZKK pic.twitter.com/hXZGvNmVJP

— Valerie Vaughn (@ValerieVaughnMD) July 11, 2023

AHA Statement | Indications, evaluation, and outcomes for dual heart-kidney and heart-liver transplantation

14 Jul, 2023 | 12:51h | UTC

Dual-Organ Transplantation: Indications, Evaluation, and Outcomes for Heart-Kidney and Heart-Liver Transplantation: A Scientific Statement From the American Heart Association – Circulation

Consensus Paper | Ten recommendations for sarcoma surgery

14 Jul, 2023 | 12:49h | UTC

Ten recommendations for sarcoma surgery: consensus of the surgical societies based on the German S3 guideline “Adult Soft Tissue Sarcomas” – Langenbeck’s Archives of Surgery

Guidelines | Management of atopic dermatitis in adults with topical therapies

14 Jul, 2023 | 12:48h | UTC

Guidelines of care for the management of atopic dermatitis in adults with topical therapies – Journal of the American Academy of Dermatology

News Release: American Academy of Dermatology issues updated guidelines for the management of atopic dermatitis in adults with topical therapies

Cohort Study | No significant difference in kidney risks between lithium and valproate therapies, but high lithium levels remain a concern

14 Jul, 2023 | 12:46h | UTC

Absolute and Relative Risks of Kidney Outcomes Associated With Lithium vs Valproate Use in Sweden – JAMA Network Open

Impact of newborn screening on severe combined immunodeficiency survival: results from a 36-year longitudinal study

14 Jul, 2023 | 12:45h | UTC

Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium – The Lancet (link to abstract – $ for full-text)

News Release: Newborn screening facilitates early identification of infants with severe combined immunodeficiency – NIH/National Institute of Allergy and Infectious Diseases/News Medical

Commentary on Twitter

Findings from a 36-year longitudinal study provide direct evidence that newborn screening for SCID has been the primary driver of improved survival in new-born babies in the USA and Canada since 2010.

Read the full article: https://t.co/TAAcPztpF9 pic.twitter.com/cOxvNNJmb9

— The Lancet (@TheLancet) July 12, 2023

RCT | Swallowing and oral-care program enhances oral-feeding resumption and reduces pneumonia post-extubation

14 Jul, 2023 | 12:44h | UTC

Effects of a swallowing and oral-care program on resuming oral feeding and reducing pneumonia in patients following endotracheal extubation: a randomized, open-label, controlled trial – Critical Care

RCT | Efficacy of different treatment regimens in unresectable colorectal cancer liver metastases

14 Jul, 2023 | 12:42h | UTC

First-line systemic treatment strategies in patients with initially unresectable colorectal cancer liver metastases (CAIRO5): an open-label, multicentre, randomised, controlled, phase 3 study from the Dutch Colorectal Cancer Group – The Lancet Oncology (link to abstract – $ for full-text)

Commentary on Twitter

ICYMI: The CAIRO5 open-label, multicentre, randomised, phase 3 trial of first-line systemic treatment strategies in patients with initially unresectable colorectal cancer liver metastases. #ccsm https://t.co/PiiwFcktLn pic.twitter.com/wlQbmuDLOW

— The Lancet Oncology (@TheLancetOncol) July 5, 2023

M-A | Drug therapies for treatment of idiopathic pulmonary fibrosis

14 Jul, 2023 | 12:40h | UTC

Drug therapies for treatment of idiopathic pulmonary fibrosis: a systematic review, Bayesian network meta-analysis, and cost-effectiveness analysis – eClinicalMedicine

Guideline | Diagnosis and treatment of fragility fractures of the pelvis

14 Jul, 2023 | 12:39h | UTC

Clinical Guidelines for the Diagnosis and Treatment of Fragility Fractures of the Pelvis – Orthopaedic Surgery

Cohort Study | Long-term cancer survivors face higher risk of noncancer death

14 Jul, 2023 | 12:38h | UTC

Relative Burden of Cancer and Noncancer Mortality Among Long-Term Survivors of Breast, Prostate, and Colorectal Cancer in the US – JAMA Network Open

Commentary on Twitter

Patients surviving ≥5 years from initial diagnosis of early breast, prostate, or colorectal cancer, the risk of dying from the cancer varied widely vs noncancer causes of death. Patients at low risk at diagnosis had a 3x higher risk of noncancer death. https://t.co/z2ffG9LqPv pic.twitter.com/HcqFkWAzZf

— JAMA Network Open (@JAMANetworkOpen) July 12, 2023