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EHRA consensus on prevention and management of interference due to medical procedures in patients with cardiac implantable electronic devices.

5 Apr, 2022 | 08:39h | UTC

EHRA consensus on prevention and management of interference due to medical procedures in patients with cardiac implantable electronic devices – EP Europace

News Release: Advice to prevent consequences of interference in cardiac device patients published today – European Society of Cardiology

 

RCT: Efficacy, safety, and immunogenicity of the DNA SARS-CoV-2 vaccine (ZyCoV-D).

5 Apr, 2022 | 08:50h | UTC

Efficacy, safety, and immunogenicity of the DNA SARS-CoV-2 vaccine (ZyCoV-D): the interim efficacy results of a phase 3, randomised, double-blind, placebo-controlled study in India – The Lancet

Invited Commentary: DNA vaccines join the fight against COVID-19 – The Lancet

 

Commentary on Twitter

 

EHRA practical guide: How to use digital devices to detect and manage arrhythmias.

5 Apr, 2022 | 08:41h | UTC

How to use digital devices to detect and manage arrhythmias: an EHRA practical guide – EP Europace

News Release: Advice on how to use digital devices to detect and manage arrhythmias published today – European Society of Cardiology

 

Review: Antiplatelet therapy after percutaneous coronary intervention.

5 Apr, 2022 | 08:38h | UTC

Antiplatelet therapy after percutaneous coronary intervention – EuroIntervention

 

Commentary on Twitter

 

M-A: Efficacy of interventions to reduce long term opioid treatment for chronic non-cancer pain.

5 Apr, 2022 | 08:29h | UTC

Efficacy of interventions to reduce long term opioid treatment for chronic non-cancer pain: systematic review and meta-analysis – The BMJ

 

Expert Consensus Statement on the state of genetic testing for cardiac diseases.

5 Apr, 2022 | 08:31h | UTC

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the state of genetic testing for cardiac diseases

News Release: Recommendations on genetic testing for inherited cardiac diseases published today – European Society of Cardiology

 

Commentary on Twitter

 

Cohort Study: Childhood cardiovascular risk factors and adult cardiovascular events.

5 Apr, 2022 | 08:23h | UTC

Childhood Cardiovascular Risk Factors and Adult Cardiovascular Events – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

RCT: Efficacy and safety of Daprodustat (oral drug) for treating anemia of chronic kidney disease in incident dialysis patients.

5 Apr, 2022 | 08:34h | UTC

Efficacy and Safety of Daprodustat for Treatment of Anemia of Chronic Kidney Disease in Incident Dialysis Patients: A Randomized Clinical Trial – JAMA Internal Medicine

Related:

RCT: In patients with chronic kidney diseases and anemia undergoing dialysis, Daprodustat (oral drug) was noninferior to darbepoetin alfa to increase hemoglobin levels and regarding cardiovascular outcomes.

RCT: In patients with chronic kidney diseases and anemia not undergoing dialysis, Daprodustat (oral drug) was noninferior to darbepoetin alfa in increasing hemoglobin levels and regarding cardiovascular outcomes.

 

Commentary on Twitter

 

Review: The intensivist’s perspective of shock, volume management, and hemodynamic monitoring.

5 Apr, 2022 | 08:20h | UTC

The Intensivist’s Perspective of Shock, Volume Management, and Hemodynamic Monitoring – Clinical Journal of the American Society of Nephrology

 

Commentary on Twitter

https://twitter.com/CJASN/status/1511025812283092992

 

Podcast: Acute pancreatitis pearls.

5 Apr, 2022 | 08:26h | UTC

#327 Acute Pancreatitis – The Curbsiders

 

Review: Patient-centered approaches for the management of unpleasant symptoms in kidney disease.

5 Apr, 2022 | 08:16h | UTC

Patient-centred approaches for the management of unpleasant symptoms in kidney disease – Nature Reviews Nephrology

 

Commentary on Twitter

 

Pericardial effusion and cardiac tamponade: pearls and pitfalls.

5 Apr, 2022 | 08:13h | UTC

Pericardial Effusion and Cardiac Tamponade: Pearls and Pitfalls – emDocs

 

Systematic Review: Prostatic arterial embolization for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia.

5 Apr, 2022 | 08:10h | UTC

Prostatic arterial embolization for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia – Cochrane Library

Summary: Prostatic arterial embolization for treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia – Cochrane Library

 

Systematic Review: Endovascular vs. conventional open surgical repair for thoracoabdominal aortic aneurysms.

5 Apr, 2022 | 08:11h | UTC

Endovascular versus conventional open surgical repair for thoracoabdominal aortic aneurysms – Cochrane Library

Summary: Are patient outcomes superior after endovascular or open surgical repair of thoracoabdominal aortic aneurysms? – Cochrane Library

 

Commentary on Twitter

 

Systematic Review: Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone fractures of the upper and lower limbs.

5 Apr, 2022 | 08:08h | UTC

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone fractures of the upper and lower limbs – Cochrane Library

Summary: The timing of treatment for broken bones in the legs and arms that also have open wounds – Cochrane Library

 

RCT: Routine lung volume recruitment is not beneficial for boys with Duchenne muscular dystrophy.

5 Apr, 2022 | 08:04h | UTC

Routine lung volume recruitment in boys with Duchenne muscular dystrophy: a randomised clinical trial – Thorax

 

M-A of randomized trials: Effects of capecitabine as part of neo-/adjuvant chemotherapy in patients with breast cancer.

5 Apr, 2022 | 08:06h | UTC

Effects of capecitabine as part of neo-/adjuvant chemotherapy – A meta-analysis of individual breast cancer patient data from 13 randomised trials including 15,993 patients – European Journal of Cancer (link to abstract – $ for full-text)

 

Review: Treatment strategies to improve outcomes in patients with chronic idiopathic constipation and irritable bowel syndrome with constipation.

5 Apr, 2022 | 08:00h | UTC

Real-World Treatment Strategies to Improve Outcomes in Patients With Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation – American Journal of Gastroenterology

 

Review: Tackling the emerging threat of antifungal resistance to human health.

5 Apr, 2022 | 08:02h | UTC

Tackling the emerging threat of antifungal resistance to human health – Nature Reviews Microbiology (if the link is paywalled, try this one)

 

#ACC22 – 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

4 Apr, 2022 | 01:42h | UTC

ACC Guideline Hub: Heart Failure

2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines – Journal of the American College of Cardiology

Executive Summary: 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure

News Release: ACC, AHA, HFSA Issue Heart Failure Guideline – American Heart Association

Key Perspectives: 2022 AHA/ACC/HFSA Heart Failure Guideline

Slide Set Download: 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure

Flipbook

 

Commentary on Twitter

 

Cohort Study: Impact of myocardial injury after coronary artery bypass grafting on long-term prognosis.

5 Apr, 2022 | 08:03h | UTC

Impact of myocardial injury after coronary artery bypass grafting on long-term prognosis – European Heart Journal

Editorial: Revisiting the definition of perioperative myocardial infarction after coronary artery bypass grafting – European Heart Journal

Related: Cohort Study: High-sensitivity Troponin I after cardiac surgery and 30-day mortality.

 

Commentary on Twitter

 

#ACC22 – RCT: Treatment for mild chronic hypertension during pregnancy is associated with better pregnancy outcomes than a strategy of reserving treatment only for severe hypertension.

4 Apr, 2022 | 01:34h | UTC

Treatment for Mild Chronic Hypertension during Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

Treating chronic hypertension in early pregnancy benefits parents, babies – NIH News Releases

CHAP: Treating Mild Chronic HTN is Associated With Better Pregnancy Outcomes – American College of Cardiology

CHAP: Better Blood Pressure Control, Better Pregnancy Outcomes – TCTMD

 

Commentary on Twitter

 

#ACC22 – RCT: Tranexamic acid reduces the risk of bleeding in patients undergoing noncardiac surgery.

4 Apr, 2022 | 01:37h | UTC

Tranexamic Acid in Patients Undergoing Noncardiac Surgery – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

POISE-3: Tranexamic Acid Reduces Severe Bleeding Risk in Patients Undergoing Noncardiac Surgery – American College of Cardiology

POISE-3: Tranexamic Acid Stems Bleeding During Noncardiac Surgery – TCTMD

 

Commentaries on Twitter

 

WHO Strategic preparedness, readiness and response plan to end the global Covid-19 emergency in 2022.

4 Apr, 2022 | 01:44h | UTC

Strategic Preparedness, Readiness and Response Plan to End the Global COVID-19 Emergency in 2022 – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge (deliberately infecting individuals in a controlled environment) in young adults.

4 Apr, 2022 | 01:27h | UTC

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults – Nature Medicine

Commentaries:

Understanding COVID-19 through human challenge models – Nature Medicine

First human challenge study of Covid-19 yields valuable insights about how we get sick – CNN

First Human Challenge Trial Shows How COVID-19 Strikes – HealthDay

Related:

Scientists deliberately gave people COVID — here’s what they learnt.

[Preprint] Results from the first Covid-19 human challenge study (deliberately infecting individuals in a controlled environment).

Perspective | SARS-CoV-2 human challenge studies — establishing the model during an evolving pandemic.

World’s first coronavirus “Human Challenge” study receives ethics approval in the UK  (several texts on the subject)

Are SARS-CoV-2 Human Challenge Trials Ethical? – “A clinical trial is underway in the UK in which young, healthy participants are exposed deliberately to SARS-CoV-2 to assess the viral inoculum needed to produce an infection and to test vaccine efficacy”.

 

Commentary on Twitter

 

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