All Posts
Guidelines for the use of cardiac magnetic resonance in pediatric congenital and acquired heart disease.
22 Jun, 2022 | 11:31h | UTC
ASCO Guideline: Management of metastatic clear cell renal cell carcinoma.
22 Jun, 2022 | 11:30h | UTC
Consensus Recommendations: Early management of patients with aneurysmal subarachnoid hemorrhage in a hospital with neurosurgical/neuroendovascular facilities.
22 Jun, 2022 | 11:25h | UTC
Comparing the Pfizer and Moderna Covid vaccines for young children.
22 Jun, 2022 | 12:02h | UTCComparing the Pfizer and Moderna Covid vaccines for young children – STAT
Related: FDA advisers OK COVID-19 vaccines for youngest kids – CIDRAP
Guideline review: EASL clinical practice guidelines: drug-induced liver injury.
22 Jun, 2022 | 11:27h | UTCOriginal Article: EASL Clinical Practice Guidelines: Drug-induced liver injury – Journal of Hepatology
Position Paper: Diagnosis and management of infections caused by multidrug-resistant bacteria.
22 Jun, 2022 | 11:23h | UTCRelated Guideline:
Review: Advanced interventions in the pre-hospital resuscitation of patients with non-compressible hemorrhage after penetrating injuries.
22 Jun, 2022 | 11:21h | UTC
Cohort Study: Association between short-term, chronic localized and chronic widespread pain and risk for cardiovascular disease.
22 Jun, 2022 | 11:18h | UTC
RCT: Efficacy and safety of varenicline for smoking cessation in patients with type 2 diabetes.
22 Jun, 2022 | 11:16h | UTCAuthor Interview: Efficacy and Safety of Varenicline in Patients With Type 2 Diabetes – JAMA
Commentary on Twitter
This randomized clinical trial (CoEHAR) found the use of varenicline in smoking cessation programs for patients with diabetes resulted in prolonged abstinence. @CoeharUnict @RiccardoPolosa https://t.co/Sd57LMcsbJ
— JAMA Network Open (@JAMANetworkOpen) June 21, 2022
RCT: Multispecies probiotic for the prevention of antibiotic-associated diarrhea in children.
22 Jun, 2022 | 11:12h | UTCMultispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Commentary: Mixed Results With Probiotic for Kids’ Antibiotic-Related Diarrhea— Randomized trial misses strictly defined endpoint, but researchers point to benefit – MedPage Today (free registration required)
Commentary on Twitter
Study found administration of a multispecies #probiotic to children had no significant effect on the risk of antibiotic-associated diarrhea caused by #Cdifficile or of unknown etiology, but reduced the overall risk of diarrhea regardless of the etiology. https://t.co/Mdq3tl8csb
— JAMA Pediatrics (@JAMAPediatrics) June 21, 2022
Retrospective cohort study: Association of patient characteristics with postoperative mortality in children undergoing tonsillectomy.
22 Jun, 2022 | 11:14h | UTCAssociation of Patient Characteristics With Postoperative Mortality in Children Undergoing Tonsillectomy in 5 US States – JAMA (free for a limited period)
RCT: High-flow nasal cannula vs. conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia.
22 Jun, 2022 | 11:09h | UTC
Randomized cross-over study: closed-loop oxygen control improves oxygen therapy in acute hypoxemic respiratory failure patients under high flow nasal oxygen.
22 Jun, 2022 | 11:08h | UTC
Systematic Review: Music therapy for people with substance use disorders.
22 Jun, 2022 | 11:02h | UTCMusic therapy for people with substance use disorders – Cochrane Library
Summary: Music therapy for people with substance use disorder – Cochrane Library
Anxiety in the medically ill: a systematic review of the literature.
22 Jun, 2022 | 11:05h | UTCAnxiety in the Medically Ill: A Systematic Review of the Literature – Frontiers in Psychology
M-A: Contemporary trends in global mortality of sepsis among young infants less than 90 days.
22 Jun, 2022 | 11:03h | UTC
Cardiovascular disease in primary Sjögren’s syndrome: raising clinicians’ awareness.
22 Jun, 2022 | 10:55h | UTC
RCT: Modified ligation procedure for prolapsed hemorrhoids vs. stapled hemorrhoidectomy for the management of symptomatic hemorrhoids.
22 Jun, 2022 | 10:59h | UTC
Commentary on Twitter
https://twitter.com/BjsOpen/status/1527612605099126787
Cohort Study: Polypharmacy, potentially inappropriate medications, and drug-drug interactions in vulnerable older adults with advanced cancer initiating cancer treatment.
22 Jun, 2022 | 10:51h | UTCCommentaries:
Polypharmacy can lead to harmful drug interactions, especially among cancer patients – News Medical
Analysis Underscores Risks of Polypharmacy in Elderly Patients With Cancer – AJMC
Commentary on Twitter
Our new article in @OncJournal : In a large cohort of older adults with advanced cancer, polypharmacy &PIM are very common. Nonprescription meds are frequently PIMs &involved in potential harmful drug interactions @WilmotCancer @rochgerionc @myCARGhttps://t.co/bA7W4kyybm pic.twitter.com/zFI3EgS320
— Mostafa R Mohamed (@m_refaat84) April 2, 2022
Under a https://creativecommons.org/licenses/by/4.0/ license
Long-term follow-up of a RCT: Nivolumab plus cabozantinib vs. sunitinib in first-line treatment for advanced renal cell carcinoma.
22 Jun, 2022 | 10:48h | UTCNivolumab plus cabozantinib versus sunitinib in first-line treatment for advanced renal cell carcinoma (CheckMate 9ER): long-term follow-up results from an open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Original Study: Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma – New England Journal of Medicine
Commentary from the author on Twitter (thread – click for more)
1/ CheckMate-9ER extended f/u (media f/u=32.9mo) results out in @TheLancetOncol: preplanned final OS analysis, updated PFS, OR & safety of Cabo/Nivo vs. Sun in 1L RCC. Also includes prespecified & post-hoc subgroup analyses. https://t.co/OJduO7Q2ar@OncoAlert @DanaFarber_GU pic.twitter.com/0EQN5gWu5I
— Toni Choueiri, MD (@DrChoueiri) June 8, 2022
Phase II RCT: Switch maintenance endocrine therapy plus bevacizumab after bevacizumab plus paclitaxel in advanced or metastatic estrogen receptor-positive, HER2-negative breast cancer.
22 Jun, 2022 | 10:49h | UTCSwitch maintenance endocrine therapy plus bevacizumab after bevacizumab plus paclitaxel in advanced or metastatic oestrogen receptor-positive, HER2-negative breast cancer (BOOSTER): a randomised, open-label, phase 2 trial – The Lancet Oncology (link to abstract – $ for full-text)
Review: Health and clinical impacts of air pollution and linkages with climate change.
21 Jun, 2022 | 11:13h | UTCHealth and Clinical Impacts of Air Pollution and Linkages with Climate Change – NEJM Evidence
Editorial: Fossil-Fuel Pollution and Climate Change — A New NEJM Group Series
Commentary on Twitter
In this review article in the NEJM Group series on #ClimateChange, Keswani and colleagues review the linkages between climate change and #AirPollution and suggest strategies that clinicians may use to mitigate the adverse health impacts of air pollution. https://t.co/dp0YETCqkY pic.twitter.com/lE8i1BklpD
— NEJM Evidence (@NEJMEvidence) June 15, 2022
RCT: In people with HIV, treating precancerous anal lesions cuts risk of anal cancer by more than half.
21 Jun, 2022 | 11:11h | UTCOriginal Study: Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/NEJM/status/1537185690961686528
Review: Climate change, fossil-fuel pollution, and children’s health.
21 Jun, 2022 | 11:14h | UTCClimate Change, Fossil-Fuel Pollution, and Children’s Health – New England Journal of Medicine
Editorial: Fossil-Fuel Pollution and Climate Change — A New NEJM Group Series
Commentary: Extreme heat poses significant and growing health risk to babies and children, study shows – CNN
Commentary on Twitter
Climate change and air pollution, largely caused by the burning of fossil fuels, pose serious harms to children’s health. Children from communities of color and low-income communities are disproportionately harmed. https://t.co/v7yY4WMEza pic.twitter.com/hXxQj282mb
— NEJM (@NEJM) June 16, 2022
RCT: Low-dose methylprednisolone does not improve outcomes in critically ill patients with severe community-acquired pneumonia.
21 Jun, 2022 | 11:04h | UTC