All Posts
M-A: Opioid versus opioid-free analgesia after surgical discharge.
21 Jun, 2022 | 11:08h | UTCOpioid versus opioid-free analgesia after surgical discharge: a systematic review and meta-analysis of randomised trials – The Lancet (link to abstract – $ for full-text)
News Release: Taking opioids at home after surgery: More harms than benefits – McGill University Health Center
RCT: Guided, internet based, cognitive behavioral therapy noninferior to individual face-to-face CBT for patients with post-traumatic stress disorder.
21 Jun, 2022 | 11:06h | UTC
Cohort Study: Cardiometabolic multimorbidity, genetic risk, and dementia.
21 Jun, 2022 | 11:01h | UTCNews Release: Multiple heart-related conditions linked to triple dementia risk regardless of genetics – University of Oxford
Related:
Genetic Risk, Midlife Life’s Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study – Neurology (link to abstract – $ for full-text) AND Commentary: Seven healthy habits linked to lower risk of dementia in those with genetic risk – American Academy of Neurology
Preventing dementia: what’s the evidence? – Evidently Cochrane
How common is long COVID? Why studies give different answers.
21 Jun, 2022 | 11:03h | UTCHow common is long COVID? Why studies give different answers – Nature
Cohort Study: Association of cardiovascular risk trajectory with cognitive decline and incident dementia.
21 Jun, 2022 | 10:58h | UTCCommentary: Heart Risk Factors Can Be Recipe for Dementia – HealthDay
Related:
Genetic Risk, Midlife Life’s Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study – Neurology (link to abstract – $ for full-text) AND Commentary: Seven healthy habits linked to lower risk of dementia in those with genetic risk – American Academy of Neurology
Preventing dementia: what’s the evidence? – Evidently Cochrane
Commentary on Twitter
Study findings show that the longitudinal, cumulative trajectory of #cardiovascular risk is predictive of #dementia risk and associated with the emergence of memory decline. Read the article: https://t.co/CT1NQ63sXO #NeuroTwitter pic.twitter.com/KMGAPLQFe7
— Neurology Journal (@GreenJournal) May 17, 2022
ERS statement on pediatric long-term noninvasive respiratory support.
21 Jun, 2022 | 10:56h | UTCERS statement on paediatric long-term noninvasive respiratory support – European Respiratory Journal
Cohort Study: Cardiometabolic multimorbidity linked to accelerated cognitive decline and dementia progression.
21 Jun, 2022 | 10:59h | UTCNews Release: Diabetes and cardiovascular disease increase dementia risk – Karolinska Institutet
Related:
Genetic Risk, Midlife Life’s Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study – Neurology (link to abstract – $ for full-text) AND Commentary: Seven healthy habits linked to lower risk of dementia in those with genetic risk – American Academy of Neurology
Preventing dementia: what’s the evidence? – Evidently Cochrane
Guidelines for the management of patients with severe acute pancreatitis.
21 Jun, 2022 | 10:57h | UTCRelated:
Evidence-Based Disposition of Acute Pancreatitis – emDocs
Pancreatitis – National Institute for Health and Care Excellence
Summary of the new 2022 AHA/ASA Guideline on intracerebral hemorrhage.
21 Jun, 2022 | 10:54h | UTCIntracerebral Hemorrhage 2022 Guideline Update – emDocs
Original Guideline: 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association – Stroke
Top Things to Know: 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage – American Heart Association
News Release: New guideline refines care for brain bleeds: compression socks, some meds not effective – American Heart Association
Consensus definition and management recommendations: intermediate-risk non–muscle-invasive bladder cancer.
21 Jun, 2022 | 10:52h | UTCIntermediate-risk Non–muscle-invasive Bladder Cancer: Updated Consensus Definition and Management Recommendations from the International Bladder Cancer Group – European Urology – Oncology (if the link is paywalled, try this one)
Commentary from the author on Twitter
Intermediate-risk NMIBC: Updated Consensus Definition & Management Recs from IBCG (International Bladder Cancer Group)
Full text: https://t.co/QaqGqRN3AE @drtanws @garysteinbergmd @DrShariat @UrogerliMD @MRoupret @spsutkaMD @joanfundi @MarekBabjuk @SWilliams_MD #bladdercancer pic.twitter.com/XQ1sdhqXPZ— Ashish M. Kamat, MD, MBBS (@UroDocAsh) June 17, 2022
Safety of bariatric surgery in patients with previous acute coronary events or heart failure: nationwide cohort study.
21 Jun, 2022 | 10:44h | UTC
Commentary on Twitter
#Bariatric surgery improves metabolic health of patients, but what are the risks if they have had MI before surgery?
National dataset matched 16000 pts🇸🇪
Heart dis assoc w/🔼 cardiac events post op, plus 🔼risk of SBO and stricture.#SoMe4Surgery https://t.co/iHsZiHIgdG pic.twitter.com/v2SXMpcZd3— BJS Open (@BjsOpen) June 17, 2022
M-A: Comparison of bifurcation techniques for percutaneous coronary intervention.
21 Jun, 2022 | 10:50h | UTC
RCT: Lisocabtagene maraleucel vs. standard of care with salvage chemotherapy followed by autologous stem cell transplantation as second-line treatment in patients with relapsed or refractory large B-cell lymphoma.
21 Jun, 2022 | 10:48h | UTCLisocabtagene maraleucel versus standard of care with salvage chemotherapy followed by autologous stem cell transplantation as second-line treatment in patients with relapsed or refractory large B-cell lymphoma (TRANSFORM): results from an interim analysis of an open-label, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Onconephrology: Update in anticancer drug-related nephrotoxicity.
21 Jun, 2022 | 10:47h | UTCOnconephrology: Update in Anticancer Drug-Related Nephrotoxicity – Nephron
Related:
Commentary from the author on Twitter
Just published! Our review about anticancer drugs related kidney injury with @PepaSolerR and @julianadraibe @SENefrologia @onconephsociety @onconefrologia @senjoven @ERAkidney @womeninnephro https://t.co/jFStKwym5z @KargerPublisher pic.twitter.com/zvbl7wxAbD
— Clara García Carro (@ClaraGCarro) June 20, 2022
Cohort Study: Association of obsessive-compulsive disorder and obsessive-compulsive symptoms with substance misuse.
21 Jun, 2022 | 10:42h | UTC
Commentary on Twitter
In this Swedish cohort study, individuals with OCD diagnosis had a nearly 4-fold risk of substance use disorders, substance-related criminal convictions or deaths. The association was partially accounted for by shared genetics. https://t.co/BDwKw227FG
— JAMA Network Open (@JAMANetworkOpen) June 6, 2022
M-A: Benefits and risks of rapid initiation of antiretroviral therapy in patients with HIV.
21 Jun, 2022 | 10:41h | UTC
M-A: Accuracy of Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography for diagnosing periprosthetic joint infections.
21 Jun, 2022 | 10:38h | UTC
M-A: Overweight/obesity in childhood and the risk of early puberty.
21 Jun, 2022 | 10:36h | UTCRelated Study: Patterns of Early Life Weight Gain and Female Onset of Puberty – Journal of the Endocrine Society
The International Penile Prosthesis Implant Consensus Forum: clinical recommendations and surgical principles on the inflatable 3-piece penile prosthesis implant.
21 Jun, 2022 | 10:35h | UTCThe International Penile Prosthesis Implant Consensus Forum: clinical recommendations and surgical principles on the inflatable 3-piece penile prosthesis implant – Nature Reviews Urology (if the link is paywalled, try this one)
RCT: Transfer of thawed frozen embryo versus fresh embryo to improve the healthy baby rate in women undergoing IVF.
21 Jun, 2022 | 10:32h | UTCRelated: Fresh versus frozen embryo transfers in assisted reproduction – Cochrane Library
Cluster RCT: Evaluation of a multicomponent intervention consisting of education and feedback to reduce benzodiazepine prescriptions by general practitioners.
21 Jun, 2022 | 10:29h | UTC
RCT: Active surveillance plus Enzalutamide monotherapy vs. active surveillance alone in patients with low-risk or intermediate-risk localized prostate cancer.
21 Jun, 2022 | 10:33h | UTCInvited Commentary: To Treat or Not to Treat Men With Low-risk or Intermediate-risk Prostate Cancer—Weighing the Evidence – JAMA Oncology (free for a limited period)
Video criticizing the article: ENACT trial | A Study That Makes Pharma Rich and Patients’ Poor | I break it down – by Vinay Prasad
Commentaries on Twitter
55% fatigue and 36% gynecomastia. In AS patients.
Why do we keep trying to escalate when the data CLEARLY say we should continue to de-escalate? https://t.co/LY1kD0jN65
— Chris Barbieri (@Chris_Barbieri1) June 17, 2022
The phase 2, open-label ENACT trial compares the efficacy & safety of enzalutamide monotherapy vs active surveillance in patients with low- or intermediate-risk localized #prostatecancer. https://t.co/q9FrL14em1 #PCSM #GUCSM
— JAMA Oncology (@JAMAOnc) June 16, 2022
Life expectancy by county, race, and ethnicity in the USA, 2000–19: a systematic analysis of health disparities.
21 Jun, 2022 | 10:28h | UTCLife expectancy by county, race, and ethnicity in the USA, 2000–19: a systematic analysis of health disparities – The Lancet (free registration required)
Commentary on Twitter (thread – click for more)
NEW Research—First comprehensive, county-level life expectancy estimates in the USA show disparities in life expectancy persist among racial and ethnic groups @IHME_UW @NIH https://t.co/oI4ODV6Oos pic.twitter.com/7qQqocEvpo
— The Lancet (@TheLancet) June 16, 2022
Associations of bilateral vestibulopathy with cognition in older adults matched with healthy controls for hearing status.
21 Jun, 2022 | 10:24h | UTC
Commentary on Twitter
In this study, older adults with #bilateralvestibulopathy had worse #cognition than their matched control. These results support an association between vestibular loss and cognitive impairment, in particular #Alzheimerdisease. https://t.co/atHR8QlWD9
— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) June 17, 2022
Clinical and immunologic analyses of a phase II trial: Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer.
21 Jun, 2022 | 10:26h | UTCNews Release: Promising results for chemo-immunotherapy combination against pancreatic cancer, Penn study finds – University of Pennsylvania
Commentary on Twitter
At #ASCO22 Symposium on targeted therapy in GI cancer?
Check out the results & biomarker analysis of the phase 2 PRINCE trial on a CD40 agonist, nivolumab and chemotherapy in #PancreaticCancer, led by speaker @laceykitch @parkerici
Published today 👉 https://t.co/8aUXuvDHIC
— Nature Medicine (@NatureMedicine) June 3, 2022