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M-A | Effectiveness and safety of new oral and injectable agents for in-hospital management of type 2 diabetes in general wards.

8 Aug, 2022 | 11:37h | UTC

Effectiveness and safety of new oral and injectable agents for in-hospital management of type 2 diabetes in general wards: systematic review and meta-analysis – Diabetes Research and Clinical Practice

 


Statistical significance and its critics: practicing damaging science, or damaging scientific practice?

8 Aug, 2022 | 11:35h | UTC

Statistical significance and its critics: practicing damaging science, or damaging scientific practice? – Synthese

Related:

Bayesian interpretation of p values in clinical trials – BMJ Evidence-Based Medicine

Scientists rise up against statistical significance – Nature

It’s time to talk about ditching statistical significance – Nature

PulmCrit- .050 shades of grey in p-value cutoffs

Statistical tests, P values, confidence intervals, and power: a guide to misinterpretations – European Journal of Epidemiology

What a nerdy debate about p-values shows about science — and how to fix it – VOX

Big names in statistics want to shake up much-maligned P value – Nature News

‘One-size-fits-all’ threshold for P values under fire – Nature News

Statisticians issue warning over misuse of P values – Nature News

Understanding common misconceptions about p-values – The 20% Statistician

The clinician’s guide to p values, confidence intervals, and magnitude of effects – Eye (if the link is paywalled, try this one)

 


RCT | Partial breast irradiation vs. whole breast irradiation for early breast cancer.

8 Aug, 2022 | 11:36h | UTC

Partial Breast Irradiation Versus Whole Breast Irradiation for Early Breast Cancer Patients in a Randomized Phase III Trial: The Danish Breast Cancer Group Partial Breast Irradiation Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)

 


RCT | Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension.

8 Aug, 2022 | 11:30h | UTC

Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension (RACE): a multicentre, phase 3, open-label, randomised controlled trial and ancillary follow-up study – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


M-A | The efficacy and safety of paravertebral block for postoperative analgesia in renal surgery.

8 Aug, 2022 | 11:32h | UTC

The efficacy and safety of paravertebral block for postoperative analgesia in renal surgery: A systematic review and meta-analysis of randomized controlled trials – Frontiers in Surgery

 


Systematic Review | Risk of adverse pregnancy outcomes prior to the onset of an autoimmune rheumatic disease.

8 Aug, 2022 | 11:28h | UTC

Risk of adverse pregnancy outcomes prior to the onset of an autoimmune rheumatic disease: a systematic review – Rheumatology

 


Systematic Review | Hydrogel dressings for venous leg ulcers.

8 Aug, 2022 | 11:27h | UTC

Hydrogel dressings for venous leg ulcers – Cochrane Library

Summary: Hydrogel dressings for venous leg ulcers – Cochrane Library

 


Systematic Review | Action observation for upper limb rehabilitation after stroke.

8 Aug, 2022 | 11:26h | UTC

Action observation for upper limb rehabilitation after stroke – Cochrane Library

 


Retrospective Cohort Study | Retrospective evaluation of ophthalmological and neurological outcomes for infants born before 24 weeks gestational age.

8 Aug, 2022 | 11:24h | UTC

Retrospective evaluation of ophthalmological and neurological outcomes for infants born before 24 weeks gestational age in a Swedish cohort – BMJ Open

 


M-A | Role of human papillomavirus (HPV) vaccination on HPV infection and recurrence of HPV related disease after local surgical treatment.

5 Aug, 2022 | 14:43h | UTC

Role of human papillomavirus (HPV) vaccination on HPV infection and recurrence of HPV related disease after local surgical treatment: systematic review and meta-analysis – The BMJ

News Release: HPV vaccination alongside surgery for cervical lesions may reduce risk of further disease – BMJ Newsroom

 


M-A | Risk factors for primary pelvic organ prolapse and prolapse recurrence.

5 Aug, 2022 | 14:42h | UTC

Risk factors for primary pelvic organ prolapse and prolapse recurrence: an updated systematic review and meta-analysis – American Journal of Obstetrics & Gynecology

 

Commentary on Twitter

 


Heavy periods: evidence to help you weigh up treatment options.

5 Aug, 2022 | 14:40h | UTC

Heavy periods: evidence to help you weigh up treatment options – Evidently Cochrane

Original Article: Interventions for heavy menstrual bleeding; overview of Cochrane reviews and network meta‐analysis – Cochrane Library

 


Cohort Study | Age at menopause and risk of heart failure and atrial fibrillation.

5 Aug, 2022 | 14:38h | UTC

Age at menopause and risk of heart failure and atrial fibrillation: a nationwide cohort study – European Heart Journal (link to abstract – $ for full-text)

Editorial: Premature menopause and cardiovascular disease: can we blame estrogen? – European Heart Journal

News Release: Premature menopause is associated with increased risk of heart problems – European Society of Cardiology

 


Guideline | Management of antithrombotic treatments in thrombocytopenic patients with cancer.

5 Aug, 2022 | 14:37h | UTC

EHA Guidelines on Management of Antithrombotic Treatments in Thrombocytopenic Patients With Cancer – HemaSphere

 


Guideline | Management of immunoglobulin replacement therapy.

5 Aug, 2022 | 14:35h | UTC

British Society for Immunology & United Kingdom Primary Immunodeficiency Network (UKPIN) consensus guideline for the management of immunoglobulin replacement therapy – Clinical and Experimental Immunology

 


Guideline (Part 2) | Treatment of decentered developmental dysplasia of the hip under the age of 1 year.

5 Aug, 2022 | 14:33h | UTC

Treatment of decentered developmental dysplasia of the hip under the age of 1 year: an evidence-based clinical practice guideline – Part 2 – Efort Open Reviews

See also: Treatment of centered developmental dysplasia of the hip under the age of 1 year: an evidence-based clinical practice guideline – Part 1 – Efort Open Reviews

 


Cohort study | Adults with Type 2 Diabetes and nonalcoholic fatty liver disease are at increased risk of severe hypoglycemia.

5 Aug, 2022 | 14:30h | UTC

Analysis of Severe Hypoglycemia Among Adults With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease – JAMA Network Open

Commentary: Consider Fatty Liver Disease for Hypoglycemia Risk in Diabetes – JAMA Network Open (free registration required)

 

Commentary on Twitter

 


Real-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study.

5 Aug, 2022 | 14:31h | UTC

Real-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study – The Lancet Psychiatry (link to abstract – $ for full-text)

 

Commentary on Twitter (thread – click for more)

 


Review | Adults with intellectual disabilities and mental health disorders in primary care.

5 Aug, 2022 | 14:24h | UTC

Adults with intellectual disabilities and mental health disorders in primary care: a scoping review – British Journal of General Practice

 


Review | Recognizing and managing eating disorders in the emergency department.

5 Aug, 2022 | 14:22h | UTC

Recognising and managing eating disorders in the emergency department – Postgraduate Medical Journal

 


Cross-Sectional Study | Experiences of everyday ageism and the health of older US adults.

5 Aug, 2022 | 14:13h | UTC

Experiences of Everyday Ageism and the Health of Older US Adults – JAMA Network Open

Commentaries:

Ageism and health: Study shows close link – Michigan Health Lab

Everyday Ageism Prevalent Among Older U.S. Adults – HealthDay

 

Commentary on Twitter

 


RCT | Antenatal dexamethasone for late preterm birth (between 34 and 36 weeks of gestation).

5 Aug, 2022 | 14:16h | UTC

Antenatal dexamethasone for late preterm birth: A multi-centre, two-arm, parallel, double-blind, placebo-controlled, randomized trial – EClinicalMedicine

 

Commentary on Twitter

 


Systematic Review | Endometrial cancer and BRCA mutations.

5 Aug, 2022 | 14:09h | UTC

Endometrial Cancer and BRCA Mutations: A Systematic Review – Journal of Clinical Medicine

 


Antimicrobial dosing recommendations in pediatric continuous renal replacement therapy: a critical appraisal of current evidence.

5 Aug, 2022 | 13:58h | UTC

Antimicrobial Dosing Recommendations in Pediatric Continuous Renal Replacement Therapy: A Critical Appraisal of Current Evidence – Frontiers in Pediatrics

 


Review | Thrombotic microangiopathy in children.

5 Aug, 2022 | 13:56h | UTC

Thrombotic microangiopathy in children – Pediatric Nephrology (if the link is paywalled, try this one)

 


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