All Posts
M-A | Effectiveness and safety of new oral and injectable agents for in-hospital management of type 2 diabetes in general wards.
8 Aug, 2022 | 11:37h | UTC
Statistical significance and its critics: practicing damaging science, or damaging scientific practice?
8 Aug, 2022 | 11:35h | UTCRelated:
Bayesian interpretation of p values in clinical trials – BMJ Evidence-Based Medicine
Scientists rise up against statistical significance – Nature
It’s time to talk about ditching statistical significance – Nature
PulmCrit- .050 shades of grey in p-value cutoffs
What a nerdy debate about p-values shows about science — and how to fix it – VOX
Big names in statistics want to shake up much-maligned P value – Nature News
‘One-size-fits-all’ threshold for P values under fire – Nature News
Statisticians issue warning over misuse of P values – Nature News
Understanding common misconceptions about p-values – The 20% Statistician
The clinician’s guide to p values, confidence intervals, and magnitude of effects – Eye (if the link is paywalled, try this one)
RCT | Partial breast irradiation vs. whole breast irradiation for early breast cancer.
8 Aug, 2022 | 11:36h | UTCPartial Breast Irradiation Versus Whole Breast Irradiation for Early Breast Cancer Patients in a Randomized Phase III Trial: The Danish Breast Cancer Group Partial Breast Irradiation Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)
RCT | Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension.
8 Aug, 2022 | 11:30h | UTCBalloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension (RACE): a multicentre, phase 3, open-label, randomised controlled trial and ancillary follow-up study – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
NEW—Pulmonary vascular resistance reduction was more pronounced with balloon pulmonary angioplasty (BPA) than with riociguat, but treatment-related SAEs were more common with BPA
Read the RACE trial from Xavier Jaïs & colleagues https://t.co/h9r3Qe2mCb
— The Lancet Respiratory Medicine (@LancetRespirMed) August 2, 2022
M-A | The efficacy and safety of paravertebral block for postoperative analgesia in renal surgery.
8 Aug, 2022 | 11:32h | UTC
Systematic Review | Risk of adverse pregnancy outcomes prior to the onset of an autoimmune rheumatic disease.
8 Aug, 2022 | 11:28h | UTC
Systematic Review | Hydrogel dressings for venous leg ulcers.
8 Aug, 2022 | 11:27h | UTCHydrogel dressings for venous leg ulcers – Cochrane Library
Summary: Hydrogel dressings for venous leg ulcers – Cochrane Library
Systematic Review | Action observation for upper limb rehabilitation after stroke.
8 Aug, 2022 | 11:26h | UTCAction observation for upper limb rehabilitation after stroke – Cochrane Library
Retrospective Cohort Study | Retrospective evaluation of ophthalmological and neurological outcomes for infants born before 24 weeks gestational age.
8 Aug, 2022 | 11:24h | UTC
M-A | Role of human papillomavirus (HPV) vaccination on HPV infection and recurrence of HPV related disease after local surgical treatment.
5 Aug, 2022 | 14:43h | UTCNews Release: HPV vaccination alongside surgery for cervical lesions may reduce risk of further disease – BMJ Newsroom
M-A | Risk factors for primary pelvic organ prolapse and prolapse recurrence.
5 Aug, 2022 | 14:42h | UTC
Commentary on Twitter
AJOG Systematic Review: Risk factors for primary pelvic organ prolapse and prolapse recurrence: an updated systematic review and meta-analysis https://t.co/9fDAzCZnj2 pic.twitter.com/GyfWE4L7EZ
— AJOG (@AJOG_thegray) August 1, 2022
Heavy periods: evidence to help you weigh up treatment options.
5 Aug, 2022 | 14:40h | UTCHeavy periods: evidence to help you weigh up treatment options – Evidently Cochrane
Original Article: Interventions for heavy menstrual bleeding; overview of Cochrane reviews and network meta‐analysis – Cochrane Library
Cohort Study | Age at menopause and risk of heart failure and atrial fibrillation.
5 Aug, 2022 | 14:38h | UTCAge at menopause and risk of heart failure and atrial fibrillation: a nationwide cohort study – European Heart Journal (link to abstract – $ for full-text)
Editorial: Premature menopause and cardiovascular disease: can we blame estrogen? – European Heart Journal
News Release: Premature menopause is associated with increased risk of heart problems – European Society of Cardiology
Guideline | Management of antithrombotic treatments in thrombocytopenic patients with cancer.
5 Aug, 2022 | 14:37h | UTC
Guideline | Management of immunoglobulin replacement therapy.
5 Aug, 2022 | 14:35h | UTC
Guideline (Part 2) | Treatment of decentered developmental dysplasia of the hip under the age of 1 year.
5 Aug, 2022 | 14:33h | UTC
Cohort study | Adults with Type 2 Diabetes and nonalcoholic fatty liver disease are at increased risk of severe hypoglycemia.
5 Aug, 2022 | 14:30h | UTCCommentary: Consider Fatty Liver Disease for Hypoglycemia Risk in Diabetes – JAMA Network Open (free registration required)
Commentary on Twitter
In this cohort study, participants with type 2 diabetes and nonalcoholic fatty liver disease without cirrhosis had a 26% increased risk of severe hypoglycemia diabetes independent of obesity status. https://t.co/Zh9tHkOmOa
— JAMA Network Open (@JAMANetworkOpen) February 23, 2022
Real-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study.
5 Aug, 2022 | 14:31h | UTCReal-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
cohort study in 1st-episode schizophrenia: The effectiveness of antipsychotics for relapse prevention decreased after the 2nd relapse. The aHR for rehospitalisation with AP use versus non-use increased from 0·42 to 0·78 after the 2nd relapse (p<0·0001) https://t.co/IBhDPNJJpe?
— P𝘧OL (@psychopharmacol) March 18, 2022
Review | Adults with intellectual disabilities and mental health disorders in primary care.
5 Aug, 2022 | 14:24h | UTC
Review | Recognizing and managing eating disorders in the emergency department.
5 Aug, 2022 | 14:22h | UTCRecognising and managing eating disorders in the emergency department – Postgraduate Medical Journal
Cross-Sectional Study | Experiences of everyday ageism and the health of older US adults.
5 Aug, 2022 | 14:13h | UTCExperiences of Everyday Ageism and the Health of Older US Adults – JAMA Network Open
Commentaries:
Ageism and health: Study shows close link – Michigan Health Lab
Everyday Ageism Prevalent Among Older U.S. Adults – HealthDay
Commentary on Twitter
In this cross-sectional study, 93% of US adults ages 50-80 reported they regularly experienced routine age-based discrimination (everyday ageism). Higher levels of everyday ageism were associated with multiple indicators of poor physical and mental health. https://t.co/ami6vUXRUQ
— JAMA Network Open (@JAMANetworkOpen) June 15, 2022
RCT | Antenatal dexamethasone for late preterm birth (between 34 and 36 weeks of gestation).
5 Aug, 2022 | 14:16h | UTC
Commentary on Twitter
Does Dexamethasone reduce neonatal mortality or respiratory distress when given to pregnant women at risk of preterm birth between 34 and 36 weeks of gestation? A newly published RCT by the WHO ACTION Collaborators in Lancet.https://t.co/ag1v3nKFkR#EBNeoAlerts#NeoEBM pic.twitter.com/j5x8nN88Fp
— Evidence-Based Neo (@EBNEO) February 13, 2022
Systematic Review | Endometrial cancer and BRCA mutations.
5 Aug, 2022 | 14:09h | UTCEndometrial Cancer and BRCA Mutations: A Systematic Review – Journal of Clinical Medicine
Antimicrobial dosing recommendations in pediatric continuous renal replacement therapy: a critical appraisal of current evidence.
5 Aug, 2022 | 13:58h | UTC
Review | Thrombotic microangiopathy in children.
5 Aug, 2022 | 13:56h | UTCThrombotic microangiopathy in children – Pediatric Nephrology (if the link is paywalled, try this one)


