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RCT | Comparison of rhomboid intercostal block, erector spinae plane block, and serratus plane block on analgesia for video-assisted thoracic surgery.

5 Sep, 2022 | 14:22h | UTC

Comparison of Rhomboid Intercostal Block, Erector Spinae Plane Block, and Serratus Plane Block on Analgesia for Video-Assisted Thoracic Surgery: A Prospective, Randomized, Controlled Trial – International Journal of Clinical Practice

 


Review | Small intestinal bacterial overgrowth breath testing in gastroenterology: clinical utility and pitfalls.

5 Sep, 2022 | 14:21h | UTC

Small Intestinal Bacterial Overgrowth Breath Testing in Gastroenterology: Clinical Utility and Pitfalls – Clinical Gastroenterology and Hepatology

 


30-month follow-up analysis of a RCT | Pembrolizumab vs. placebo as post-nephrectomy adjuvant therapy for clear cell renal cell carcinoma.

5 Sep, 2022 | 14:20h | UTC

Pembrolizumab versus placebo as post-nephrectomy adjuvant therapy for clear cell renal cell carcinoma (KEYNOTE-564): 30-month follow-up analysis of a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial – The Lancet Oncology

Invited Commentary: Adjuvant immunotherapy for renal cell carcinoma – The Lancet Oncology

Original Article: Adjuvant Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma – New England Journal of Medicine

 


RCT | Telaglenastat failed to improve the efficacy of Cabozantinib in patients with advanced renal cell carcinoma.

5 Sep, 2022 | 14:19h | UTC

Efficacy and Safety of Telaglenastat Plus Cabozantinib vs Placebo Plus Cabozantinib in Patients With Advanced Renal Cell Carcinoma: The CANTATA Randomized Clinical Trial – JAMA Oncology (free for a limited period)

 

Commentary on Twitter

https://twitter.com/JAMAOnc/status/1565368902674178048

 


Nonalcoholic fatty liver disease: review of management for primary care providers.

5 Sep, 2022 | 14:18h | UTC

Nonalcoholic Fatty Liver Disease: Review of Management for Primary Care Providers – Mayo Clinic Proceedings

 


Volatile anesthetics for ICU sedation: the future of critical care or niche therapy?

5 Sep, 2022 | 14:16h | UTC

Volatile anesthetics for ICU sedation: the future of critical care or niche therapy? – Intensive Care Medicine

 

Commentary on Twitter

 


Systematic Review | Antifungal therapies for allergic bronchopulmonary aspergillosis in people with cystic fibrosis.

5 Sep, 2022 | 14:15h | UTC

Antifungal therapies for allergic bronchopulmonary aspergillosis in people with cystic fibrosis – Cochrane Library

Summary: Treatments to fight fungal infections that cause allergic bronchopulmonary aspergillosis in people with cystic fibrosis – Cochrane Library

 


Systematic Review | Hydroxyurea for sickle cell disease.

5 Sep, 2022 | 14:14h | UTC

Hydroxyurea (hydroxycarbamide) for sickle cell disease – Cochrane Library

Summary: Hydroxyurea (also known as hydroxycarbamide) for people with sickle cell disease – Cochrane Library

 


Systematic Review | Contrast‐enhanced ultrasound for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease.

5 Sep, 2022 | 14:13h | UTC

Contrast‐enhanced ultrasound for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease – Cochrane Library

Summary: How accurate are contrast-enhanced ultrasound scans for detecting hepatocellular carcinoma? – Cochrane Library

 


RCT | Daily written care summaries for families of critically ill patients.

5 Sep, 2022 | 14:12h | UTC

Daily Written Care Summaries for Families of Critically Ill Patients: A Randomized Controlled Trial – Critical Care Medicine

Editorial: More Documentation? Who Needs It? – Critical Care Medicine

 


2022 ACC Expert Consensus | Role of nonstatin therapies for LDL-cholesterol lowering and managing cardiovascular disease risk.

2 Sep, 2022 | 13:17h | UTC

2022 ACC Expert Consensus Decision Pathway on the Role of Nonstatin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of Cardiology Solution Set Oversight Committee – Journal of the American College of Cardiology

News Release: ACC Issues Guidance to Address New Nonstatin Therapies – American College of Cardiology

Commentary: New on the Scene Nonstatin Drugs: Experts Provide Guidance – TCTMD

 

Commentary on Twitter

 


RCT | Bedaquiline–Pretomanid–Linezolid regimens for drug-resistant tuberculosis.

2 Sep, 2022 | 13:16h | UTC

Bedaquiline–Pretomanid–Linezolid Regimens for Drug-Resistant Tuberculosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Three drug regimen with Linezolid 600 mg tied to better outcomes in drug-resistant TB – Medical Dialogues

 


RCT | Fractional flow reserve or intravascular ultrasonography to guide percutaneous coronary intervention.

2 Sep, 2022 | 13:15h | UTC

Fractional Flow Reserve or Intravascular Ultrasonography to Guide PCI – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Fractional Flow Reserve Noninferior to IVUS for Guiding PCI – HealthDay

 


Cohort Studies | Increased consumption of ultra-processed foods linked to increased risk of mortality and cancer.

2 Sep, 2022 | 13:15h | UTC

Study 1: Association of ultra-processed food consumption with colorectal cancer risk among men and women: results from three prospective US cohort studies – The BMJ

Study 2: Joint association of food nutritional profile by Nutri-Score front-of-pack label and ultra-processed food intake with mortality: Moli-sani prospective cohort study – The BMJ

Editorial: The trouble with ultra-processed foods – The BMJ

Commentaries:

Expert reaction to two studies looking at ultra-processed foods and heart disease, bowel cancer and death – Science Media Centre

Ultraprocessed foods linked to cancer and early death, studies find – CNN

New research gives more reasons to eat less-processed food – The Guardian

 


Systematic Review | Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse.

2 Sep, 2022 | 13:08h | UTC

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse – Cochrane Library

 

Commentary on Twitter

 


JCS 2022 Guideline on management and re-interventional therapy in patients with congenital heart disease in the long-term after the initial repair.

2 Sep, 2022 | 13:10h | UTC

JCS 2022 Guideline on Management and Re-Interventional Therapy in Patients With Congenital Heart Disease Long-Term After Initial Repair – Circulation Journal

 


M-A | Which surgeries are the best choice for chronic pancreatitis.

2 Sep, 2022 | 13:05h | UTC

Which Surgeries Are the Best Choice for Chronic Pancreatitis: A Network Meta-Analysis of Randomized Controlled Trials – Frontiers in Surgery

 


Systematic Review | Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use.

2 Sep, 2022 | 13:07h | UTC

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use – Cochrane Library

 


Systematic Review | Adverse drug reactions in pediatric onco-hematology

2 Sep, 2022 | 13:05h | UTC

Adverse Drug Reactions in Pediatric Oncohematology: A Systematic Review – Frontiers in Pharmacology

 


Mycosis fungoides in pediatric population: comprehensive review on epidemiology, clinical presentation, and management.

2 Sep, 2022 | 13:02h | UTC

Mycosis fungoides in pediatric population: comprehensive review on epidemiology, clinical presentation, and management – International Journal of Dermatology

 


3-year outcomes of a RCT | First-line nivolumab plus ipilimumab versus chemotherapy in patients with unresectable malignant pleural mesothelioma.

2 Sep, 2022 | 13:04h | UTC

First-line nivolumab plus ipilimumab versus chemotherapy in patients with unresectable malignant pleural mesothelioma: 3-year outcomes from CheckMate 743 – Annals of Oncology

Original Study: Randomized trial: First-line nivolumab plus ipilimumab in unresectable malignant pleural mesothelioma

Related: Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

 


Efficacy and activity of PD-1 blockade in patients with advanced esophageal squamous cell carcinoma: a systematic review and meta-analysis with focus on the value of PD-L1 combined positive score

2 Sep, 2022 | 13:03h | UTC

Efficacy and activity of PD-1 blockade in patients with advanced esophageal squamous cell carcinoma: a systematic review and meta-analysis with focus on the value of PD-L1 combined positive score – ESMO Open

 


AHA Scientific Statement | Management of infective endocarditis in people who inject drugs.

1 Sep, 2022 | 12:00h | UTC

Management of Infective Endocarditis in People Who Inject Drugs: A Scientific Statement From the American Heart Association – Circulation

News Release: Addiction management is key to treating heart infection in people who inject drugs – American Heart Association

Top Things to Know: Infective Endocarditis in People Who Inject Drugs – American Heart Association

Video: Management of Infective Endocarditis in People who Inject Drugs – American Heart Association

Commentaries:

Infective Endocarditis in People Who Inject Drugs: A Call for Patient-Centered, Multidisciplinary Care – American Heart Association

AHA Addresses Infective Endocarditis in Injection Drug Users – HealthDay

Related: Management of Infective Endocarditis in People Who Inject Drugs – American College of Cardiology (the original article is paywalled but has an informative infographic)

 


Review | Covid-19 vaccines — immunity, variants, boosters.

1 Sep, 2022 | 11:57h | UTC

Covid-19 Vaccines — Immunity, Variants, Boosters – New England Journal of Medicine

 


After the genome—a brief history of proteomics.

1 Sep, 2022 | 11:58h | UTC

After the Genome—A Brief History of Proteomics – JAMA (free for a limited period)

Video: Proteomics 101 – JAMA

 

Commentary on Twitter

 


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