All Posts
Abbreviated lipid guidelines for clinical practice
13 Feb, 2023 | 12:46h | UTCOriginal Guidelines
#ESCCongress – 2019 ESC/EAS Guidelines for the Management of Dyslipidaemias
#ESCCongress – 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice.
Related:
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease – Circulation
Phase 2 RCT | Effects of Difelikefalin in notalgia paresthetica
13 Feb, 2023 | 12:42h | UTCPhase 2 Trial of Difelikefalin in Notalgia Paresthetica – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
Phase 2 Trial Finds Difelikefalin Could Prove Useful in Notalgia Paresthetica – HCP Live
Difelikefalin Improves Itch Intensity in Notalgia Paresthetica – HealthDay
Commentary on Twitter
In a phase 2 trial in notalgia paresthetica, oral difelikefalin treatment resulted in modestly reduced itch as compared with placebo. https://t.co/MQMO7z4o0W pic.twitter.com/2iaCgb3c93
— NEJM (@NEJM) February 8, 2023
Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations
13 Feb, 2023 | 12:44h | UTC
RCT | Preliminary study on the effects of low-dose colchicine in patients undergoing non-CABG cardiac surgery
13 Feb, 2023 | 12:43h | UTC
Commentary on Twitter
✅Colchicine reduced cardiac injury after cardiac surgery
132 pts randomized to
💊0.5 mg of colchicine or placebo in the perioperative periodColchicine compared with placebo
Cardiac makers⬇️
Atrial fibrillation⬇️ (few events, though)🔓https://t.co/c2mZmvj6kQ#CardioTwitter pic.twitter.com/N3DUjr1WsB
— 小谷 祐樹 | Yuki KOTANI (@YukiKotani5) February 8, 2023
RCT | Ide-cel (a CAR-T cell treatment) vs. standard regimens in relapsed and refractory multiple myeloma
13 Feb, 2023 | 12:41h | UTCIde-cel or Standard Regimens in Relapsed and Refractory Multiple Myeloma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
Ide-Cel Beneficial in Relapsed, Refractory Multiple Myeloma – HealthDay
Ide-cel Improves PFS vs SOC in Relapsed/Refractory Multiple Myeloma – OncLive
RCT | Allo-HCT vs. standard consolidation chemotherapy in patients with intermediate-risk AML
13 Feb, 2023 | 12:40h | UTCAllogeneic Hematopoietic Cell Transplantation vs Standard Consolidation Chemotherapy in Patients With Intermediate-Risk Acute Myeloid Leukemia: A Randomized Clinical Trial – JAMA Oncology (free for a limited period)
Commentary on Twitter
Rand trial suggests pts with intermediate-risk AML & matched donor have a significantly improved disease free-survival with allo-HCT during first complete remission (69% vs. 40%) but similar overall surv w/consol chemo & allo HCT only after relapse. https://t.co/TJR9fqcYc9
— JAMA Oncology (@JAMAOnc) February 9, 2023
M-A | Complications of percutaneous tracheostomy in critically ill adults with obesity
13 Feb, 2023 | 12:37h | UTCComplication Rate of Percutaneous Dilatational Tracheostomy in Critically Ill Adults With Obesity: A Systematic Review and Meta-analysis – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)
US infant pertussis incidence trends before and after implementation of the maternal Tdap vaccine
13 Feb, 2023 | 12:38h | UTCUS Infant Pertussis Incidence Trends Before and After Implementation of the Maternal Tetanus, Diphtheria, and Pertussis Vaccine – JAMA Pediatrics (free for a limited period)
Commentary: Maternal Tdap Vaccination Protects Youngest Infants From Pertussis – HealthDay
Commentary on Twitter
Study findings suggest that maternal #Tdap vaccination is associated with a reduction in #pertussis among infants younger than 2 months, the strategy’s target age group. https://t.co/a5h3z2zXY2
— JAMA Pediatrics (@JAMAPediatrics) February 7, 2023
Brief Review | Double sequential external defibrillation for refractory ventricular fibrillation
13 Feb, 2023 | 12:35h | UTC
Commentary on Twitter
🫀Refractory Vfib
⚡️ vector change defibrillation
⚡️ double sequential external defibrillation
exciting & innovative strategies that can improve survival for patients presenting with refractory VF: time will tell if will be broadly implemented/embraced
🖇️ https://t.co/uUktOHdGEl pic.twitter.com/aiOtMMX2nT— Intensive Care Medicine (@yourICM) February 9, 2023
SR | Spin and fragility in randomized controlled trials in the anesthesia literature
13 Feb, 2023 | 12:33h | UTCSpin and fragility in randomised controlled trials in the anaesthesia literature: a systematic review – British Journal of Anaesthesiology (free for a limited period)
Using Risk of Bias 2 to assess results from randomized controlled trials: guidance from Cochrane
13 Feb, 2023 | 12:34h | UTC
Review | Advanced point-of-care bedside monitoring for acute respiratory failure
13 Feb, 2023 | 12:32h | UTCAdvanced Point-of-care Bedside Monitoring for Acute Respiratory Failure – Anesthesiology
Commentary on Twitter
Advanced respiratory monitoring involves several mini- or noninvasive tools, applicable at bedside, that have the potential to support clinicians in the management of acute respiratory failure. Learn more about the personalization of ventilatory strategy: https://t.co/RP4LAsdQHM pic.twitter.com/KFlwxDthe9
— Anesthesiology (@_Anesthesiology) February 10, 2023
Brief Review | Surgical management of ulcerative colitis
13 Feb, 2023 | 12:30h | UTCSurgical management of ulcerative colitis – British Journal of Surgery
A guide to indoor rock climbing injuries
13 Feb, 2023 | 12:31h | UTCA Guide to Indoor Rock Climbing Injuries – Current Sports Medicine Reports (free for a limited period)
M-A | Exercise-based cardiac rehabilitation for coronary heart disease
13 Feb, 2023 | 12:28h | UTC
Umbrella review of basket trials testing a drug in tumors with actionable genetic biomarkers
13 Feb, 2023 | 12:26h | UTC
Brief Review | Contemporary management of parastomal hernia
13 Feb, 2023 | 12:29h | UTCContemporary management of parastomal hernia – British Journal of Surgery
RCT | Hyaluronic acid spacer for hypofractionated prostate radiation therapy
13 Feb, 2023 | 12:25h | UTC
Commentary on Twitter
Multicenter randomized clin trial in prostate cancer tested presence or absence of hyaluronic acid rectal spacer before receiving hypofractionated radiation, showed acute grade >2 GI toxicity in 2.9% of pts w/spacer vs. 13.8% in control group #PCSM #RadOnc https://t.co/eTifx0b1x2
— JAMA Oncology (@JAMAOnc) February 9, 2023
Consensus Statement | Development of an Enhanced Recovery After Surgery (ERAS) surgical safety checklist
10 Feb, 2023 | 14:03h | UTC
Commentary from the author on Twitter (thread – click for more)
The @WHO Surgical Safety Checklist and the @ErasSociety guidelines come together.🔥
#ERAS teams can leverage 2 tools in 1 to improve care in critical perioperative communication moments https://t.co/EaXYyj7b56
via @JAMANetworkOpen part of @JAMANetwork pic.twitter.com/WHJMjThubO— Mary Brindle (@MaryEBrindle) February 8, 2023
Guideline for management of septic arthritis in native joints
10 Feb, 2023 | 14:00h | UTC
Position Paper | Diagnosis, prevention and treatment of common shoulder injuries in sport
10 Feb, 2023 | 14:01h | UTC
Commentary on Twitter
Common shoulder injuries 💪 – grading the evidence on: 📊
🔍 Diagnosis – included 19 clinical tests
✋ Prevention – injury prevention programmes
🏋️♂️ Treatment – stretching, ice packs, strengthening, compressionStatement paper commissioned by DSSF
➡️ https://t.co/CN7usTd3HR pic.twitter.com/xavDN5MICY
— British Journal of Sports Medicine (BJSM) (@BJSM_BMJ) January 16, 2023
Resistant hypertension: a stepwise approach
10 Feb, 2023 | 13:58h | UTCResistant hypertension: A stepwise approach – Cleveland Clinic Journal of Medicine
Brief Review | Mpox — A rapidly evolving disease
10 Feb, 2023 | 13:56h | UTCMpox—A Rapidly Evolving Disease – JAMA Dermatology
Related:
Monkeypox (hMPXV infection): A practical review – American Journal of Medicine
WHO renames “monkeypox” as “mpox” to help destigmatize the disease.
Study shows there is substantial monkeypox transmission before symptoms appear.
Monkeypox – New England Journal of Medicine
Monkeypox: disease epidemiology, host immunity and clinical interventions.
Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
RCT | Argatroban plus Alteplase not better than Alteplase alone in patients with acute ischemic stroke
10 Feb, 2023 | 13:59h | UTCEffect of Argatroban Plus Intravenous Alteplase vs Intravenous Alteplase Alone on Neurologic Function in Patients With Acute Ischemic Stroke: The ARAIS Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
Among patients with acute ischemic #stroke who received intravenous alteplase, argatroban was not significantly associated with better neurologic function. https://t.co/s9BDEvRvFA pic.twitter.com/HIRnGmiWMU
— JAMA (@JAMA_current) February 9, 2023
RCT | AI improves nodule detection on chest radiographs in a health screening population
10 Feb, 2023 | 13:55h | UTCNews Release: AI Improves Lung Nodule Detection on Chest X-Rays – RSNA News