All Posts

SR | Mechanical plus oral antibiotic bowel preparation may prevent complications in elective colorectal surgery

10 Feb, 2023 | 13:53h | UTC

Preoperative combined mechanical and oral antibiotic bowel preparation for preventing complications in elective colorectal surgery – Cochrane Library

Summary: Can combined mechanical and oral antibiotic bowel preparation reduce the risk of complications after scheduled colon or rectal resections compared with purely mechanical, purely oral antibiotic or no bowel preparation? – Cochrane Library

Related:

M-A: Strategies for antibiotic administration for bowel preparation among patients undergoing elective colorectal surgery – “the addition of oral antibiotics to intravenous antibiotics was associated with a reduction in the incidence of incisional surgical site infection by more than 50%”.

Meta-Analysis: Effects of Mechanical Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery

 

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Opinion | Interpreting the results from the first randomized controlled trial of colonoscopy: does it save lives?

10 Feb, 2023 | 13:54h | UTC

Interpreting the results from the first randomised controlled trial of colonoscopy: does it save lives? – BMJ Evidence Based Medicine

Original Study: RCT | Effect of colonoscopy screening on risks of colorectal cancer and related death.

 

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RCT | Effectiveness of Mycophenolate Mofetil among patients with progressive IgA nephropathy

10 Feb, 2023 | 13:52h | UTC

Effectiveness of Mycophenolate Mofetil Among Patients With Progressive IgA Nephropathy: A Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

RCT: For patients with IgA nephropathy at high risk of disease progression, addition of mycophenolate to optimized supportive care reduced risk of kidney function loss, vs supportive care alone. https://t.co/xjyD3hseG7 pic.twitter.com/BlQiXkyBLn

— JAMA Network Open (@JAMANetworkOpen) February 6, 2023

 

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Consensus Statement | Evaluation and management of patients with diabetes and heart failure

10 Feb, 2023 | 13:51h | UTC

Evaluation and Management of Patients with Diabetes and Heart Failure: A Korean Diabetes Association and Korean Society of Heart Failure Consensus Statement – Diabetes & Metabolism Journal

Related:

ACC/AHA/HFSA 2022 and ESC 2021 guidelines on heart failure comparison – ESC Heart Failure

#ACC22 – 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

#ESCCongress – 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure – SGLT2 inhibitors are now recommended for patients with heart failure with reduced ejection fraction regardless of the presence of diabetes.

 

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Consensus Paper | Biological treatment of bipolar disorder during the acute, maintenance, and mixed phases

10 Feb, 2023 | 13:50h | UTC

Taiwan consensus on biological treatment of bipolar disorder during the acute, maintenance, and mixed phases: The 2022 update – Asian Journal of Psychiatry

Related:

Bipolar depression: the clinical characteristics and unmet needs of a complex disorder – Current Medical Research and Opinion

Bipolar disorder: assessment and management – National Institute for Health and Care Excellence

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder – Bipolar Disorders

Systematic Review: Treatment for Bipolar Disorder in Adults – Agency for Healthcare Research and Quality (free)

 

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Korean Medication Algorithm Project for Bipolar Disorder 2022: comparisons with other treatment guidelines

10 Feb, 2023 | 13:49h | UTC

Korean Medication Algorithm Project for Bipolar Disorder 2022: Comparisons with Other Treatment Guidelines – Clininical Psychopharmacology and Neuroscience

 

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Consensus Paper | Use of cerebral CT angiography to support a clinical diagnosis of death using neurological criteria

10 Feb, 2023 | 13:48h | UTC

The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline – Anaesthesia

 

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Cohort Study | Associations between betablockers and psychiatric and behavioral outcomes

10 Feb, 2023 | 13:47h | UTC

Associations between β-blockers and psychiatric and behavioural outcomes: A population-based cohort study of 1.4 million individuals in Sweden – PLOS Medicine

 

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Systematic estimates of the global, regional and national under-5 mortality burden attributable to birth defects in 2000–2019

10 Feb, 2023 | 13:46h | UTC

Systematic estimates of the global, regional and national under-5 mortality burden attributable to birth defects in 2000–2019: a summary of findings from the 2020 WHO estimates – BMJ Open

 

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SR | Cognitive aids in the management of clinical emergencies

10 Feb, 2023 | 13:44h | UTC

Cognitive aids in the management of clinical emergencies: a systematic review – Anaesthesia

 

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Review | Management of adult patients with hematological malignancies in critical care

10 Feb, 2023 | 13:45h | UTC

Management of adult patients with haematological malignancies in critical care – Anaesthesia

 

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Review | Postoperative systemic inflammatory dysregulation and corticosteroids

10 Feb, 2023 | 13:44h | UTC

Postoperative systemic inflammatory dysregulation and corticosteroids: a narrative review – Anaesthesia

 

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Review | Recommendations for reducing exposure to medical X ray irradiation

10 Feb, 2023 | 13:43h | UTC

Recommendations for reducing exposure to medical X‑ray irradiation (Review) – Medicine International

 

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RCT | Efficacy and safety of bimekizumab in axial spondyloarthritis

10 Feb, 2023 | 13:42h | UTC

Efficacy and safety of bimekizumab in axial spondyloarthritis: results of two parallel phase 3 randomised controlled trials – Annals of the Rheumatic Diseases

Related:

Bimekizumab in patients with active psoriatic arthritis and previous inadequate response or intolerance to tumour necrosis factor-α inhibitors: a randomised, double-blind, placebo-controlled, phase 3 trial (BE COMPLETE) – The Lancet

Bimekizumab in patients with psoriatic arthritis, naive to biologic treatment: a randomised, double-blind, placebo-controlled, phase 3 trial (BE OPTIMAL) – The Lancet

Bimekizumab versus Secukinumab in Plaque Psoriasis – New England Journal of Medicine

Bimekizumab versus Adalimumab in Plaque Psoriasis – New England Journal of Medicine

 

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Review | What’s new in the management of neonatal early-onset sepsis?

10 Feb, 2023 | 13:40h | UTC

What’s new in the management of neonatal early-onset sepsis? – ADC Fetal & Neonatal Edition (free for a limited period)

 

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Cohort Study | Fecal hemoglobin concentrations are associated with all-cause mortality in colorectal cancer screening

10 Feb, 2023 | 13:41h | UTC

Faecal haemoglobin concentrations are associated with all-cause mortality and cause of death in colorectal cancer screening – BMC Medicine

Commentary: Faecal haemoglobin concentrations associated with mortality and cause of death in colorectal cancer screening – Physician’s Weekly

 

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RCT | Consumption of 2 green kiwifruits daily improves constipation and abdominal comfort

10 Feb, 2023 | 13:39h | UTC

Consumption of 2 Green Kiwifruits Daily Improves Constipation and Abdominal Comfort—Results of an International Multicenter Randomized Controlled Trial – The American Journal of Gastroenterology

 

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POTS and Pregnancy: a review of literature and recommendations for evaluation and treatment

10 Feb, 2023 | 13:37h | UTC

POTS and Pregnancy: A Review of Literature and Recommendations for Evaluation and Treatment – International Journal of Women’s Health

 

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M-A | Effect of SGLT-2 inhibitors on body composition in patients with type 2 diabetes mellitus

10 Feb, 2023 | 13:38h | UTC

Effect of SGLT-2 inhibitors on body composition in patients with type 2 diabetes mellitus: A meta-analysis of randomized controlled trials – PLOS One

 

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RCT | Genicular nerve block vs. intra-articular triamcinolone in juvenile idiopathic arthritis

10 Feb, 2023 | 13:36h | UTC

Genicular nerve block in juvenile idiopathic arthritis: a randomized clinical trial – Clinical Rheumatology

 

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Review | Handling missing data in clinical research

10 Feb, 2023 | 13:34h | UTC

Handling missing data in clinical research – Journal of Clinical Epidemiology

Related: Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide – BMJ Open

 

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Guillain–Barré syndrome following influenza vaccination: a 15-year nationwide population-based case–control study

10 Feb, 2023 | 13:35h | UTC

Guillain–Barré syndrome following influenza vaccination: A 15-year nationwide population-based case–control study – European Journal of Neurology

Commentary: Influenza vaccination increases risk of Guillain-Barre syndrome within one month – Medical Dialogues

 

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Sex differences in clinical features, treatment, and lifestyle factors in patients with cluster headache

10 Feb, 2023 | 13:33h | UTC

Sex Differences in Clinical Features, Treatment, and Lifestyle Factors in Patients With Cluster Headache – Neurology

Commentaries:

Differences ID’d Between Men, Women With Cluster Headache – HealthDay

Cluster Headaches Affect Men More Often, But It’s Women Who Are Hit Hardest – Science Alert

 

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SHEA/IDSA/APIC Recommendations | Strategies to prevent healthcare-associated infections through hand hygiene

9 Feb, 2023 | 14:08h | UTC

SHEA/IDSA/APIC Practice Recommendation: Strategies to prevent healthcare-associated infections through hand hygiene: 2022 Update – Infection Control & Hospital Epidemiology

 

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RCT | Sublobar resection noninferior to lobal resection for peripheral stage IA non–small-cell lung cancer

9 Feb, 2023 | 14:05h | UTC

Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Less lung tissue removal needed for early-stage cancer, study finds – Weill Cornell Medical College

Related:

Survival outcomes in a prospective randomized multicenter Phase III trial comparing patients undergoing anatomical segmentectomy versus standard lobectomy for non-small cell lung cancer up to 2 cm – Lung Cancer

A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation.

Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer – The Korean Journal of Thoracic and Cardiovascular Surgery

 

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