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Report – Open Science by Design: Realizing a Vision for 21st Century Research

20 Jul, 2018 | 02:51h | UTC

Open Science by Design: Realizing a Vision for 21st Century Research (2018) – National Academies of Sciences, Engineering, and Medicine (free PDF)

News Release: Report Proposes Recommendations and New Framework to Speed Progress Toward Open Science (free)

 


Review: Auscultation for Bowel Sounds in Patients with Ileus

20 Jul, 2018 | 02:46h | UTC

Auscultation for bowel sounds in patients with ileus: an outdated practice in the ICU? – Netherlands Journal of Critical Care (free PDF)

Editorial: It’s not a gut feeling: don’t listen to the bowels (free PDF)

Source: Critical Care Reviews Newsletter

 


Head To Head: Does Evidence Based Medicine Adversely Affect Clinical Judgment?

20 Jul, 2018 | 02:49h | UTC

Does evidence based medicine adversely affect clinical judgment? – The BMJ (free) (via @michelaccad)

 


Systematic Review: Harms Reporting in Trials with Probiotics

20 Jul, 2018 | 02:48h | UTC

Harms Reporting in Randomized Controlled Trials of Interventions Aimed at Modifying Microbiota: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Reporting on risks often inadequate for prebiotics, probiotics, synbiotics – ACP Internist (free) AND Probiotics studies often don’t disclose safety data or risks, report finds – STAT (free) AND Safety of Probiotic Supplements Is Not Guaranteed, Study Says – Consumer Reports (free)

“How to make an intervention safe? Don’t report the adverse events”. (via @EricTopol see Tweet)

 


Review: Noninvasive Ventilation in Acute Respiratory Failure

20 Jul, 2018 | 02:47h | UTC

Noninvasive ventilation in acute respiratory failure: which recipe for success? – European Respiratory Review (free)

Source: Critical Care Reviews Newsletter

 


Systematic Review: Nurses as Substitutes for Doctors in Primary Care

20 Jul, 2018 | 02:44h | UTC

Nurses as substitutes for doctors in primary care – Cochrane Library (free)

Summary: Nurses as substitutes for doctors in primary care – Cochrane Library (free)

“This updated Cochrane Review indicates that nurses can effectively expand the capacity of the primary care workforce”.

 


Cohort Study: Occult Blood in Feces is Associated with All-cause and Non-colorectal Cancer Mortality

20 Jul, 2018 | 02:46h | UTC

Occult blood in faeces is associated with all-cause and non-colorectal cancer mortality – Gut (free)

Commentaries: FOB associated with rise in all-cause mortality – OnMedica (free) AND 3 key findings from Gut study on all-cause mortality associated with occult blood in stool – GI & Endoscopy (free) AND Fecal Occult Blood Flags Risks Beyond Colon Cancer – MedPage Today (free)

 


WHO: 9 in 10 Infants Worldwide Received Vaccinations in 2017

20 Jul, 2018 | 02:29h | UTC

9 in 10 infants worldwide received vaccinations in 2017 – World Health Organization (free)

 


Clinical Review: Novel Therapies for Diabetes Mellitus in Pregnancy

20 Jul, 2018 | 02:42h | UTC

Novel therapies for diabetes mellitus in pregnancy – The BMJ (free for a limited period)

 


Study: Overprescription of Antibiotics in Urgent Care Clinics

20 Jul, 2018 | 02:43h | UTC

Comparison of Antibiotic Prescribing in Retail Clinics, Urgent Care Centers, Emergency Departments, and Traditional Ambulatory Care Settings in the United States – JAMA Internal Medicine (free for a limited period)

Commentaries: Overprescription in Urgent Care Clinics—The Fast and the Spurious – JAMA Internal Medicine (free for a limited period) AND Urgent care centers often prescribe unnecessary antibiotics – Reuters (free) AND Study spotlights inappropriate prescribing in urgent care – CIDRAP (free)

 


Report: Integrating Responses at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics

20 Jul, 2018 | 02:29h | UTC

Integrating Responses at the Intersection of Opioid Use Disorder and Infectious Disease Epidemics: Proceedings of a Workshop – National Academies of Sciences, Engineering and Medicine (free)

Commentaries: National Academies target opioid abuse and infectious disease consequences – Emory Health Sciences (free) AND Within opioid abuse epidemic, infectious disease epidemic emerges – Reuters (free)

 


Perspective: Is Your Cellphone Giving you Cancer?

20 Jul, 2018 | 02:26h | UTC

Is your cellphone giving you cancer? A comprehensive guide to the messy, frustrating research – VOX (free)

 


Richard Lehman’s Journal Review – 16 July 2018

20 Jul, 2018 | 02:28h | UTC

Richard Lehman’s journal review, 16 July 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 


Cluster Randomized Trial: Smartphone-based Screening for Visual Impairment in Children

20 Jul, 2018 | 02:22h | UTC

Smartphone-based screening for visual impairment in Kenyan school children: a cluster randomised controlled trial – The Lancet Global Health (free)

Commentaries: Strengthening eye health evidence for children in low-income and middle-income countries – The Lancet Global Health (free) AND App screening boosts children’s eye health – Medical Health News (free)

 


Cohort Study: Fertility Treatments and Cancer Risk

20 Jul, 2018 | 02:24h | UTC

Risks of ovarian, breast, and corpus uteri cancer in women treated with assisted reproductive technology in Great Britain, 1991-2010: data linkage study including 2.2 million person years of observation – The BMJ (free)

Commentaries: No association found between fertility treatment, some types of cancer – ACP Internist (free) AND Fertility treatment does not appear to raise serious cancer risk – OnMedica (free)

 


Position Statement: Reducing Inappropriate Medication Use & Polypharmacy

20 Jul, 2018 | 02:21h | UTC

International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action – Drugs & Aging (free)

Related: Polypharmacy Guidance, Realistic Prescribing 3 rd Edition, 2018 – Scottish Government Polypharmacy Model of Care Group (free PDF) AND The Challenge of Polypharmacy: From Rhetoric to Reality – Royal Pharmaceutical Society and Royal College of General Practitioners Partnership (free PDF) AND Common ED Medication Errors: Polypharmacy – emDocs (free) AND Current and future perspectives on the management of polypharmacy – BMC Family Practice (free) AND The other big drug problem: Older people taking too many pills – The Whashington Post (free) AND Routine deprescribing of chronic medications to combat polypharmacy – Therapeutic Advances in Drug Safety (free) AND Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international (free) AND Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety (free)Too Many Meds? America’s Love Affair With Prescription Medication – Consumer Reports (free) AND CaDeN Deprescribing Guidelines and Algorithms (free) 

 


Study: Global Mapping of Vulnerability to Snakebite Envenoming

20 Jul, 2018 | 02:18h | UTC

Vulnerability to snakebite envenoming: a global mapping of hotspots – The Lancet (free)

Commentaries: Addressing the global challenge of snake envenoming – The Lancet (free) AND New study maps the areas where people are most vulnerable to death following snakebite – London School of Tropical Medicine (free) AND New study finds 93 million people vulnerable to death from snakebites – Institute for Health Metrics and Evaluation (free)

 


EULAR Recommendations: Physical Activity in People with Inflammatory Arthritis and Osteoarthritis

20 Jul, 2018 | 02:15h | UTC

2018 EULAR recommendations for physical activity in people with inflammatory arthritis and osteoarthritis – Annals of Rheumatic Disease (free)

 


Meta-Analysis: Effects of Aspirin for CV Disease Prevention According to Bodyweight and Dose

20 Jul, 2018 | 02:20h | UTC

Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials – The Lancet (free)

Commentaries: Weight-adjusted aspirin for cardiovascular prevention – The Lancet (free) AND One dose of aspirin doesn’t fit all – University of Oxford (free)

Practice Changing Article. “Low doses of aspirin (75–100 mg) were only effective in preventing vascular events in patients weighing less than 70 kg, and had no benefit in the 80% of men and nearly 50% of all women weighing 70 kg or more. By contrast, higher doses of aspirin were only effective in patients weighing 70 kg or more.”

 


Cohort Study: Inferior Vena Cava Filters and Mortality in Patients with Contraindication to Anticoagulation

20 Jul, 2018 | 02:17h | UTC

Association of Inferior Vena Cava Filter Placement for Venous Thromboembolic Disease and a Contraindication to Anticoagulation With 30-Day Mortality – JAMA Network Open (free)

Commentaries: Inferior Vena Cava Filters and Mortality: Is It the Underlying Process, the Patient, or the Device? (free)

“Could IVC filters be causing harm? They began being used before @US_FDA started approving devices. This article raises possibility of increased mortality. Maybe where we need trials to determine safety and effectiveness”. (via @hmkyale see Tweet)

 


Guideline: Management of Non ST-segment Elevation Acute Coronary Syndrome

20 Jul, 2018 | 02:14h | UTC

2018 Guidelines of the Taiwan Society of Cardiology, Taiwan Society of Emergency Medicine and Taiwan Society of Cardiovascular Interventions for the management of non ST-segment elevation acute coronary syndrome – Journal of the Formosan Medical Association (free)

Related Guidelines: 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation (free) AND 2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes (free)

 


Expert Consensus: Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction

20 Jul, 2018 | 02:13h | UTC

CVIT expert consensus document on primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) in 2018 – Japanese Association of Cardiovascular Intervention and Therapeutics (free)

 


Study: Machine Learning of Toxicological Big Data May Outperforming Animal Tests

20 Jul, 2018 | 02:12h | UTC

Machine learning of toxicological big data enables read-across structure activity relationships (RASAR) outperforming animal test reproducibility – Toxicological Sciences (free)

Commentaries: New digital chemical screening tool could help eliminate animal testing – Science (free) AND Database Analysis More Reliable Than Animal Testing For Toxic Chemicals – Johns Hopkins Bloomberg School of Public Health (free) AND Software beats animal tests at predicting toxicity of chemicals – Nature News (free)

 


Cardiac Rehabilitation: A Class 1 Recommendation

20 Jul, 2018 | 02:11h | UTC

Cardiac rehabilitation: A class 1 recommendation – Cleveland Clinic Journal of Medicine (free)

Related Guidelines: Cardiac rehabilitation – Scottish Intercollegiate Guidelines Network (free) AND Myocardial infarction: cardiac rehabilitation and prevention of further cardiovascular disease – National Institute for Health and Care Excellence (free)

 


Study: Biomarkers of Dairy Fat and Total and Cause-specific Mortality

20 Jul, 2018 | 02:08h | UTC

Serial measures of circulating biomarkers of dairy fat and total and cause-specific mortality in older adults: the Cardiovascular Health Study – American Journal of Clinical Nutrition (free for a limited period)

Commentaries: Study finds no significant link between whole dairy products and heart disease, stroke – News Medical (free) AND Full-fat dairy may actually benefit heart health – Medical News Today (free)

Related Studies: Meta-Analysis: Cheese consumption and risk of cardiovascular disease (link to abstract and commentaries) AND Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality (free study and commentaries)

 


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