Archives

“Last week a new review said: – Over half of people taking antidepressants experience withdrawal symptoms – These symptoms are severe in over half of cases. The press had a field day! Our blog today by @J_F_Hayes and @sameerjauhar offers a different view” (via @Mental_Elf see Tweet)

Study: Deep Learning Algorithms for Detection of Critical Findings in Head CT Scans

19 Oct, 2018 | 00:08h | UTC

Deep learning algorithms for detection of critical findings in head CT scans: a retrospective study – The Lancet (link to abstract – $ for full-text)

Commentary: AI: Deep Learning Algorithms Can Detect Critical Head CT Findings – MedicalResearch.com (free)

Cohort Study: Aspirin vs. Other Anticoagulants for Prevention of VTE After Total Knee Arthroplasty

19 Oct, 2018 | 00:06h | UTC

Association of Aspirin With Prevention of Venous Thromboembolism in Patients After Total Knee Arthroplasty Compared With Other Anticoagulants: A Noninferiority Analysis – JAMA Surgery (link to abstract – $ for full-text)

Commentaries: More Research Supports Use of Aspirin Alone to Prevent VTE After Knee Replacement Surgery – TCTMD (free) AND Aspirin Noninferior to Other Anticoagulants in Knee Arthroplasty – Journal Watch (free)

Related Randomized Trial: Aspirin Starting Five Days After Hip or Knee Arthroplasty for VTE Prophylaxis (link to abstract, video summary and commentary)

Thu, October 18 – 10 Stories of The Day!

18 Oct, 2018 | 00:01h | UTC

1 – Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016–40 for 195 countries and territories – The Lancet (free)

Commentaries: Major strides in forecasting future health – The Lancet (free) AND Why Life Expectancy in 2040 Could Be Lower Than It Is Today – LiveScience (free) AND How healthy will we be in 2040? – Institute for Health Metrics and Evaluation (free)

2 – Acute Flaccid Myelitis Investigation Page – Centers for Disease Control and Prevention (free)

Commentaries: CDC, partners probe 127 polio-like cases in 22 states – CIDRAP (free) AND CDC Investigates Cases Of Rare Neurological ‘Mystery Illness’ In Kids – NPR (free) AND Acute Flaccid Myelitis Cases Confirmed in 22 States Physician’s First Watch (free) AND CDC expresses concern over mysterious surge in polio-like paralysis cases – STAT (free)

3 – Survivorship, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network (free)

Related: Cardiovascular Toxicity in Cancer Survivors (free review and guidelines) AND Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors (link to abstract and commentaries) AND The cumulative burden of surviving childhood cancer (link to abstract and commentaries) AND Endocrine Late Effects in Survivors of Cancer in Adolescence and Young Adulthood (free study and commentaries) AND Endocrine Disorders in Survivors of Childhood Cancer (free guideline and commentaries)

4 – Australia is responding to the complex challenge of overdiagnosis – The Medical Journal of Australia (free for 7 days)

Commentaries: Overdiagnosis: a deep cultural problem – MJA InSight (free) AND Overdiagnosis is harming patients and action is required, says chief medical officer – The Sidney Morning Herald (free)

5 – Podcast: #119 Nutrition Pearls, Heart Health, Bacon – Curbsiders Internal Medicine Podcast (free audio and summary)

6 – Sarcopenia: revised European consensus on definition and diagnosis – Age and Ageing (free)

7 – Position Statement: Guidelines for vitamin K prophylaxis in newborns: A joint statement of the Canadian Paediatric Society and the College of Family Physicians of Canada – Canadian Family Physician (free)

8 – Progestogen for preventing miscarriage in women with recurrent miscarriage of unclear etiology – Cochrane Library (free for a limited period)

Summary: Progestogen for preventing miscarriage – Cochrane Library (free)

9 – Deep Learning to Distinguish Recalled but Benign Mammography Images in Breast Cancer Screening – Clinical Cancer Research (free PDF)

Commentaries: Study Finds Deep Learning Can Distinguish Recalled-Benign Mammogram Images From Malignant and Negative Cases – The ASCO Post (free) AND AI distinguishes false-positive mammograms from malignant, negative mammograms – Radiology Business (free) AND Deep learning can distinguish recalled-benign mammograms from malignant and negative images – eCancer News (free)

10 – Hospital Readmission Following Takotsubo Syndrome – European Heart Journal – Quality of Care and Clinical Outcomes (link to abstract – $ for full-text)

Commentaries: Takotsubo Syndrome Linked to Heart Failure Admissions and Mortality Risk in Nationwide Study – TCTMD (free) AND Avoiding Broken-Heart Syndrome Readmissions – MedPage Today (free registration required)

Related: International Registry: Long-Term Prognosis of Patients With Takotsubo Syndrome (link to abstract and commentaries) International Expert Consensus Document on Takotsubo Syndrome (free guideline) AND Review: Takotsubo Syndrome (free reviews)

Fri, October 19 – 10 Stories of The Day!

19 Oct, 2018 | 00:01h | UTC

1 – Pre-eclampsia and risk of dementia later in life: nationwide cohort study – The BMJ (free)

Editorial: Pre-eclampsia and the brain (free)

Commentaries: Pre-eclampsia linked to raised risk of vascular dementia – OnMedica (free) AND Pre-eclampsia linked to an increased risk of dementia later in life – The BMJ (free)

2 – Perspective: To Prevent Cardiovascular Disease, Pay Attention to Pregnancy Complications – JAMA (free for a limited period)

Related: Hypertensive Disorders of Pregnancy and Maternal Cardiovascular Disease (link to abstract and commentaries)

3 – Enhanced Recovery in Surgical Intensive Care: A Review – Frontiers in Medicine (free)

4 – Review: Newer technologies for detection of atrial fibrillation – The BMJ (free for a limited period)

5 – Effect of Cricoid Pressure Compared With a Sham Procedure in the Rapid Sequence Induction of Anesthesia: The IRIS Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Commentaries: Is 30 Newtons of Prevention Worth a Pound of a Cure?—Cricoid Pressure – JAMA Surgery (free for a limited period) AND The Case of the Inferior Superiority – EMNerd (free)

6 – US FDA Breast Implant Postapproval Studies: Long-term Outcomes in 99,993 Patients – Annals of Surgery (free)

Commentary: Long-term safety of silicone breast implants still unclear – Reuters (free)

7 – See It, Want It, Buy It, Eat It – Cancer Research UK (free PDF)

Commentaries: Time spent by children online linked to requests for junk food – University of Liverpool (free) AND Does TV and internet advertising feed children’s junk food habits? – NHS Choices (free)

8 – Deep learning algorithms for detection of critical findings in head CT scans: a retrospective study – The Lancet (link to abstract – $ for full-text)

Commentary: AI: Deep Learning Algorithms Can Detect Critical Head CT Findings – MedicalResearch.com (free)

9 – Antidepressant withdrawal: reviewing the paper behind the headlines – The Mental Elf (free) (via @AllenFrancesMD)

Original Systematic Review: Antidepressant Withdrawal Effects (free article and commentaries)

10 – Association of Aspirin With Prevention of Venous Thromboembolism in Patients After Total Knee Arthroplasty Compared With Other Anticoagulants: A Noninferiority Analysis – JAMA Surgery (link to abstract – $ for full-text)

Commentaries: More Research Supports Use of Aspirin Alone to Prevent VTE After Knee Replacement Surgery – TCTMD (free) AND Aspirin Noninferior to Other Anticoagulants in Knee Arthroplasty – Journal Watch (free)

Related Randomized Trial: Aspirin Starting Five Days After Hip or Knee Arthroplasty for VTE Prophylaxis (link to abstract, video summary and commentary)

Perspective: Australia is responding to the complex challenge of overdiagnosis

17 Oct, 2018 | 19:19h | UTC

Australia is responding to the complex challenge of overdiagnosis – The Medical Journal of Australia (free for 7 days)

Commentaries: Overdiagnosis: a deep cultural problem – MJA InSight (free) AND Overdiagnosis is harming patients and action is required, says chief medical officer – The Sidney Morning Herald (free)

NCCN Guideline: Small Cell Lung Cancer

17 Oct, 2018 | 13:42h | UTC

NCCN Guidelines Insights: Small Cell Lung Cancer, Version 2.2018. – Journal of the National Comprehensive Cancer Network (free)

Report: Forecasting Life Expectancy, Years of Life Lost, and All-Cause and Cause-Specific Mortality in 2040

17 Oct, 2018 | 13:20h | UTC

Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016–40 for 195 countries and territories – The Lancet (free)

Commentaries: Major strides in forecasting future health – The Lancet (free) AND Why Life Expectancy in 2040 Could Be Lower Than It Is Today – LiveScience (free) AND How healthy will we be in 2040? – Institute for Health Metrics and Evaluation (free)

NCCN Survivorship Care Guideline 2018

17 Oct, 2018 | 13:36h | UTC

Survivorship, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network (free)

Related: Cardiovascular Toxicity in Cancer Survivors (free review and guidelines) AND Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors (link to abstract and commentaries) AND The cumulative burden of surviving childhood cancer (link to abstract and commentaries) AND Endocrine Late Effects in Survivors of Cancer in Adolescence and Young Adulthood (free study and commentaries) AND Endocrine Disorders in Survivors of Childhood Cancer (free guideline and commentaries)

CDC Investigates Acute Flaccid Myelitis Cases

17 Oct, 2018 | 13:03h | UTC

Acute Flaccid Myelitis Investigation Page – Centers for Disease Control and Prevention (free)

Commentaries: CDC, partners probe 127 polio-like cases in 22 states – CIDRAP (free) AND CDC Investigates Cases Of Rare Neurological ‘Mystery Illness’ In Kids – NPR (free) AND Acute Flaccid Myelitis Cases Confirmed in 22 States Physician’s First Watch (free) AND CDC expresses concern over mysterious surge in polio-like paralysis cases – STAT (free)

Wed, October 17 – 10 Stories of The Day!

17 Oct, 2018 | 00:01h | UTC

1 – Association Between Bariatric Surgery and Macrovascular Disease Outcomes in Patients With Type 2 Diabetes and Severe Obesity – JAMA (link to abstract – $ for full-text)

Video Summary: How Does Bariatric Surgery Compare With Medical Care for Reducing Cardiovascular Disease in Patients With Type 2 Diabetes? (free)

Commentary: Obesity surgery may lower heart attack danger in diabetics – Associated Press (free)

2 – Perspective: The New Age of Patient Autonomy: Implications for the Patient-Physician Relationship – JAMA (free for a limited period) (via @EricTopol)

3 – Perspective: What should we stop doing in the ICU? – ICU Management & Practice (free)

4 – Perspective: I hate guidelines (but they can improve and you can help) – First10Em (free) (via @srrezaie)

5 – Review: Treatments targeting inotropy – European Heart Journal (free)

6 – Review: Disseminated Intravascular Coagulation: An Update on Pathogenesis, Diagnosis, and Therapeutic Strategies – Clinical and Applied Thrombosis/Hemostasis (free)

Source: Critical Care Reviews Newsletter

7 – Researcher Requests for Inappropriate Analysis and Reporting: A U.S. Survey of Consulting Biostatisticians – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: When scientists want their data fudged and why you should care – CBC (free)

8 – Heart disease used to be an ailment of the rich. But it’s now striking the world’s poor. – VOX (free)

“In 2016, an estimated 1 million people died of HIV/AIDS, 445,000 people died of malaria, and 1.7 million died of tuberculosis. Nearly 18 million died of heart disease. And more than three-quarters of those deaths occurred in the developing world.”

9 – Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems – Cochrane Library (free for a limited period)

Summary: Calcium supplementation during pregnancy for preventing blood pressure disorders and related problems – Cochrane Library (free)

10 – Early clindamycin for bacterial vaginosis in pregnancy (PREMEVA): a multicentre, double-blind, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Study: Antibiotics for bacterial vaginosis don’t cut preterm birth risk – CIDRAP (free)