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The Female Athlete’s Heart: Facts and Fallacies

4 Dec, 2018 | 23:39h | UTC

The Female Athlete’s Heart: Facts and Fallacies – Current Treatment Options in Cardiovascular Medicine (free)

 


Systematic Review: Cardiac Rehabilitation and Exercise Prescription in Symptomatic Patients with Non-Obstructive Coronary Artery Disease

4 Dec, 2018 | 23:44h | UTC

Cardiac Rehabilitation and Exercise Prescription in Symptomatic Patients with Non-Obstructive Coronary Artery Disease—a Systematic Review – Current Treatment Options in Cardiovascular Medicine (free)

 


Review: Novel Treatments in Lupus

4 Dec, 2018 | 23:38h | UTC

Novel Treatments in Lupus – Frontiers in Immunology (free)

 


Cardiac Screening of Young Athletes: a Practical Approach to Sudden Cardiac Death Prevention

4 Dec, 2018 | 23:42h | UTC

Cardiac Screening of Young Athletes: a Practical Approach to Sudden Cardiac Death Prevention – Current Treatment Options in Cardiovascular Medicine (free)

 


Review: Is It Possible to Predict the Future in First-Episode Psychosis?

4 Dec, 2018 | 23:38h | UTC

Is It Possible to Predict the Future in First-Episode Psychosis? – Frontiers in Psychiatry (free)

 


Systematic Review: Systemic Capillary Leak Syndrome (Clarkson Syndrome) in Cancer Patients

4 Dec, 2018 | 23:36h | UTC

Systemic Capillary Leak Syndrome (Clarkson Syndrome) in Cancer Patients: A Systematic Review – Journal of Clinical Medicine (free)

 


Wed, December 5 – 10 Stories of The Day!

5 Dec, 2018 | 00:01h | UTC

 

1 – Finding the Balance Between Benefits and Harms When Using Statins for Primary Prevention of Cardiovascular Disease: A Modeling Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Statins may be significantly overprescribed for primary prevention, computer model suggests – ACP Internist (free) AND Benefits of Statins Only Exceed Harms at Higher 10-Year Risk Thresholds, Study Suggests – TCTMD (free) AND Higher Risk Thresholds May Be Needed for Starting Statins for Primary CVD Prevention, Study Suggests – NEJM Journal Watch (free) AND Statins are being overprescribed, study suggests – OnMedica (free)

 

2 – The Ethics of Heritable Genome Editing: New Considerations in a Controversial Area – JAMA (free for a limited period)

Related: WHO looks at standards in ‘uncharted water’ of gene editing – Reuters (free) AND The CRISPR Baby Scandal Gets Worse by the Day – The Atlantic (free) AND We need a temporary moratorium on using gene editing to create babies – STAT (free) AND Is the CRISPR baby controversy the start of a terrifying new chapter in gene editing? – VOX (free) AND First CRISPR babies: six questions that remain – Nature (free) AND ‘I feel an obligation to be balanced.’ Noted biologist comes to defense of gene editing babies – Science (free)

 

3 – Fasting-Evoked En Route Hypoglycemia in Diabetes (FEEHD): An Overlooked Form of Hypoglycemia in Clinical Practice – International Journal of Endocrinology (free)

Commentary: Fasting for lab tests isn’t good for patients with diabetes – Michigan State University (free)

 

4 – Last Month in Oncology with Dr. Bishal Gyawali: November 2018 – eCancer News (free)

 

5 – Review: Confounders of severe asthma: diagnoses to consider when asthma symptoms persist despite optimal therapy – World Allergy Organization Journal (free)

 

6 – Perspective: Potential Risks and Benefits of Mental Health Screening of Physicians – JAMA (free for a limited period)

 

7 – Perspective: Why the world is becoming more allergic to food – BBC (free)

 

8 – Clinical validation of a risk scale for serious outcomes among patients with chronic obstructive pulmonary disease managed in the emergency department – Canadian Medical Association Journal (free)

News Release: Tool identifies which patients with COPD are at risk of death, serious complications (free)

Commentary: Tool quickly identifies risk for deadly COPD complications – UPI (free)

 

9 – Predictors of dementia misclassification when using brief cognitive assessments – Neurology (free PDF)

Commentary: Study Finds Biases in Widely Used Dementia Identification Tests – University of Exeter (free) AND Primary Care Tests Flunk for Classifying Dementia – MedPage Today (free registration required) AND Brief Cognitive Exams Commonly Misdiagnose Dementia – NEJM Journal Watch (free)

 

10 – Body-weight fluctuation and incident diabetes mellitus, cardiovascular disease, and mortality: a 16-year prospective cohort study – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)

Commentaries: Weight cycling is associated with a higher risk of death – The Endocrine Society (free) AND Study: Yo-yo diets can increase death risk – UPI (free)

 


Randomized Trial: Natriuretic Peptide–Guided Therapy for Heart Failure

4 Dec, 2018 | 00:06h | UTC

Economic and Quality-of-Life Outcomes of Natriuretic Peptide–Guided Therapy for Heart Failure – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Natriuretic peptide-guided therapy falls flat in improving HFrEF outcomes – Cardiovascular Business (free) AND Quality-of-Life Outcomes With Natriuretic Peptide-Guided Therapy for Heart Failure – Cardiology Advisor (free)

 


Tue, December 4 – 10 Stories of The Day!

4 Dec, 2018 | 00:10h | UTC

 

1 – Why the HIV epidemic is not over – World Health Organization (free)

 

2 – Clinical Report: Selecting Appropriate Toys for Young Children in the Digital Era – American Academy of Pediatrics (free)

News Release: Best toys for children’s development? Hint: They are not electronic or costly – AAP News (free)

Commentaries: AAP Offer Toy Tips for Parents and Clinicians in the Digital Age – NEJM Journal Watch (free) AND Empty boxes top high-tech toys on doctor-recommended list – Associated Press (free)

 

3 – Perspective: Why Hospitals Should Let You Sleep – The New York Times (10 articles per month are free)

“Frequent disruptions are more than just annoying for patients. They can also cause harm.”

 

4 – Podcast: #128 Aspirin Overhyped and Overused – The Curbsiders Internal Medicine Podcast (free)

 

5 – Editorial: Focus on randomised clinical trials – Intensive Care Medicine (free PDF) (via @CritCareReviews)

Related: What should we stop doing in the ICU? – ICU Management & Practice (free)

“Their results add to what appears to be a constant theme in critical care, ‘less is more’ based on RCT results”

 

6 – Alex Nowbar’s weekly research reviews, 3 December 2018 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 

7 – Interpreting the Athlete’s ECG: Current State and Future Perspectives – Current Treatment Options in Cardiovascular Medicine (free)

 

8 – Economic and Quality-of-Life Outcomes of Natriuretic Peptide–Guided Therapy for Heart Failure – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Natriuretic peptide-guided therapy falls flat in improving HFrEF outcomes – Cardiovascular Business (free) AND Quality-of-Life Outcomes With Natriuretic Peptide-Guided Therapy for Heart Failure – Cardiology Advisor (free)

 

9 – Clinical practice guidelines for older people with multimorbidity and life-limiting illness: what are the implications for deprescribing? – Therapeutic Advances in Drug Safety (free)

 

10 – Impact of patient and public involvement on enrolment and retention in clinical trials: systematic review and meta-analysis – The BMJ (free)

Commentaries: Joanna Crocker: Time to embrace patient involvement in clinical trials? – The BMJ Opinion (free) AND “Researchers don’t know what they’re missing”—the impact of patient involvement in research – The BMJ Opinion (free) AND Impact of PPI in clinical trials – University of Oxford (free)

 


Interpreting the Athlete’s ECG: Current State and Future Perspectives

4 Dec, 2018 | 00:06h | UTC

Interpreting the Athlete’s ECG: Current State and Future Perspectives – Current Treatment Options in Cardiovascular Medicine (free)

 


Clinical Report: Selecting Appropriate Toys for Young Children in the Digital Era

4 Dec, 2018 | 00:07h | UTC

Selecting Appropriate Toys for Young Children in the Digital Era – American Academy of Pediatrics (free)

News Release: Best toys for children’s development? Hint: They are not electronic or costly – AAP News (free)

Commentaries: AAP Offer Toy Tips for Parents and Clinicians in the Digital Age – NEJM Journal Watch (free) AND Empty boxes top high-tech toys on doctor-recommended list – Associated Press (free)

 


WHO: Why the HIV Epidemic is Not Over

4 Dec, 2018 | 00:04h | UTC

Why the HIV epidemic is not over – World Health Organization (free)

 


Editorial: Focus on Randomised Clinical Trials

4 Dec, 2018 | 00:05h | UTC

Focus on randomised clinical trials – Intensive Care Medicine (free PDF) (via @CritCareReviews)

Related: What should we stop doing in the ICU? – ICU Management & Practice (free)

“Their results add to what appears to be a constant theme in critical care, ‘less is more’ based on RCT results”

 


Alex Nowbar’s Weekly Research Reviews – 3 December 2018

4 Dec, 2018 | 00:02h | UTC

Alex Nowbar’s weekly research reviews, 3 December 2018 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Guidelines for Older People with Multimorbidity and Life-Limiting Illness: Implications for Deprescribing

4 Dec, 2018 | 00:01h | UTC

Clinical practice guidelines for older people with multimorbidity and life-limiting illness: what are the implications for deprescribing? – Therapeutic Advances in Drug Safety (free)

 


Perspective: Why Hospitals Should Let You Sleep

4 Dec, 2018 | 00:02h | UTC

Why Hospitals Should Let You Sleep – The New York Times (10 articles per month are free)

“Frequent disruptions are more than just annoying for patients. They can also cause harm.”

 


Meta-Analysis: Impact of Patient and Public Involvement on Enrolment and Retention in Clinical Trials

3 Dec, 2018 | 23:57h | UTC

Impact of patient and public involvement on enrolment and retention in clinical trials: systematic review and meta-analysis – The BMJ (free)

Commentaries: Joanna Crocker: Time to embrace patient involvement in clinical trials? – The BMJ Opinion (free) AND “Researchers don’t know what they’re missing”—the impact of patient involvement in research – The BMJ Opinion (free) AND Impact of PPI in clinical trials – University of Oxford (free)

 


Podcast: Aspirin Overhyped and Overused

3 Dec, 2018 | 23:55h | UTC

#128 Aspirin Overhyped and Overused – The Curbsiders Internal Medicine Podcast (free)

 


Carotid Blowout Syndrome: Modern Trends in Management

3 Dec, 2018 | 23:48h | UTC

Carotid blowout syndrome: modern trends in management – Cancer Management and Research (free)

 


Systematic Review: Regional Anesthesia in Pediatric Surgical Patients

3 Dec, 2018 | 23:49h | UTC

Regional anesthesia to ameliorate postoperative analgesia outcomes in pediatric surgical patients: an updated systematic review of randomized controlled trials – Local and Regional Anesthesia (free)

 


Review: Benign Paroxysmal Positional Vertigo in the Elderly

3 Dec, 2018 | 23:46h | UTC

Benign paroxysmal positional vertigo in the elderly: current insights – Clinical Interventions in Aging (free)

 


Review: Antibiotic Resistance in Pseudomonas Aeruginosa

3 Dec, 2018 | 23:45h | UTC

Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies – Biotechnology Advances (free)

 


Review: Conversion Surgery for Gastric Cancer Patients

3 Dec, 2018 | 23:42h | UTC

Conversion surgery for gastric cancer patients: A review – World Journal of Gastrointestinal Oncology (free)

 


Meta-Analysis: Effectiveness of Antiepileptic Medications as Prophylaxis of Early Seizure in Traumatic Brain Injury

3 Dec, 2018 | 23:44h | UTC

The Effectiveness of Antiepileptic Medications as Prophylaxis of Early Seizure in Traumatic Brain Injury Patients Compared to Placebo or No Treatment: A Systematic Review and Meta-Analysis – World Neurosurgery (link to abstract – $ for full-text)

Commentary: Early seizure prophylaxis with antiepileptics in TBI has only modest effects – Univadis (free registration required)

 


tudy: Axicabtagene Ciloleucel in Refractory Large B-cell Lymphoma

3 Dec, 2018 | 23:41h | UTC

Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial – The Lancet Oncology (free)

Commentary: ASH 2018: More than half of patients alive two years after receiving CAR-T therapy for diffuse large B-cell lymphoma in ZUMA-1 trial – eCancer News (free)

 


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