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Guideline: Management of Paediatric Ulcerative Colitis

7 Dec, 2018 | 01:12h | UTC

Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care—An Evidence-based Guideline From European Crohn’s and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition (free)

Part 2: Acute Severe Colitis (free)

 


Meta-Analysis: The Effects of Macrolides in Children with Reactive Airway Disease

7 Dec, 2018 | 01:15h | UTC

The effects of macrolides in children with reactive airway disease: a systematic review and meta-analysis of randomized controlled trials – Drug Design, Development and Therapy (free)

 


Perspective: Universal Flu Vaccine Remains ‘An Alchemist’s Dream’

7 Dec, 2018 | 01:16h | UTC

Universal flu vaccine remains ‘an alchemist’s dream’ – Science (free)

 


Perspective: Understanding Organisational Culture for Healthcare Quality Improvement

7 Dec, 2018 | 01:13h | UTC

Understanding organisational culture for healthcare quality improvement – The BMJ (free)

 


Perspective: Statistical Pitfalls of Personalized Medicine

7 Dec, 2018 | 01:11h | UTC

Statistical pitfalls of personalized medicine – Nature (free)

 


Systematic Review: Impact of Goiter and Thyroid Surgery on Esophageal Dysfunction

7 Dec, 2018 | 01:09h | UTC

The Impact of Goiter and Thyroid Surgery on Goiter Related Esophageal Dysfunction. A Systematic Review – Frontiers in Endocrinology (free)

 


Perspective: Biomedical Research is Becoming More Open About its Funding and Data

7 Dec, 2018 | 01:10h | UTC

Biomedical research is becoming more open about its funding and data – Nature (free)

 


Systematic Review: Antibiotic Prophylaxis in Foot and Ankle Surgery

7 Dec, 2018 | 01:07h | UTC

Antibiotic prophylaxis in foot and ankle surgery: a systematic review of the literature – Journal of Foot and Ankle Research (free)

 


Meta-Analysis: The Effect of Exercise on Gestational Diabetes Mellitus in Normal-Weight Women

7 Dec, 2018 | 01:08h | UTC

The effect of exercise during pregnancy on gestational diabetes mellitus in normal-weight women: a systematic review and meta-analysis – BMC Pregnancy and Childbirth (free)

 


Fri, December 7 – 10 Stories of The Day!

7 Dec, 2018 | 00:10h | UTC

 

1 – 2018 ACC Expert Consensus Decision Pathway on Tobacco Cessation Treatment – Journal of the American College of Cardiology (free)

Summary: 2018 ACC Decision Pathway on Tobacco Cessation Treatment – American College of Cardiology (free)

 

2 – Anesthesia interventions that alter perioperative mortality: a scoping review – Systematic Review (free)

 

3 – Apixaban to Prevent Venous Thromboembolism in Patients with Cancer – New England Journal of Medicine (free)

Commentary: NOACs Significantly Curb Risk of VTE in Cancer Patients – TCTMD (free)

 

4 – 2018 recommendations for the management of community acquired pneumonia – Jornal Brasileiro de Pneumologia (free PDF)

Related Guideline: Pneumonia in adults: diagnosis and management – National Institute for Health and Care Excellence (free)

 

5 – Review: Assessment and initial management of acute undifferentiated fever in tropical and subtropical regions – The BMJ (free for a limited period)

 

6 – Review: Diaphragmatic dysfunction – Pulmonology (free)

 

7 – Review: Examination of the Patient with Dizziness or Imbalance – Medical Clinics of North America (free)

 

8 – Perspective: Risk-Reducing Mastectomy in BRCA1 and BRCA2 Mutation Carriers: A Complex Discussion – JAMA (free for a limited period)

 

9 – China backs bold plan to tear down journal paywalls – Nature (free)

Related: Europe’s Bold Open-Access Plan Detailed (free report and commentaries)

 

10 – Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker – Nature Communications (free)

Commentaries: One test to diagnose them all: researchers exploit cancers’ unique DNA signature – The Conversation (free) AND Nano-signature discovery could revolutionise cancer diagnosis – University of Queensland (free) AND ‘Universal fingerprint’ in cancer DNA points to potential blood test. But it’s not ready for patients – Cancer Research UK (free) AND Holy grail cancer test? Hold on. Here’s what you need to know – HealthNewsReview (free)

 


Thu, December 6 – 10 Stories of The Day!

6 Dec, 2018 | 00:01h | UTC

 

1 – Systematic Review: What are the most common conditions in primary care? – Canadian Family Physician (free)

 

2 – Perspective: Whole-Fat or Nonfat Dairy? The Debate Continues – JAMA (free for a limited period)

 

3 – Livebirth after uterus transplantation from a deceased donor in a recipient with uterine infertility – The Lancet (link to abstract – $ for full-text)

Commentaries: For the first time, a baby is born via a uterus transplant from a deceased donor – STAT (free) AND Mother gives birth with uterus from deceased donor – OnMedica (free) AND Expert reaction to first baby born by uterus transplant from a deceased donor – Science Media Centre (free) AND First baby born after deceased womb transplant – BBC (free)

 

4 – 2018 Korean Guideline of Atrial Fibrillation Management – Korean Circulatory Journal (free)

Related Guidelines: 2018 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation (free) AND 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (free)

 

5 – Nurse staffing, nursing assistants and hospital mortality: retrospective longitudinal cohort study – BMJ Quality & Safety (free)

Commentaries: Lack of nurses linked to increased risk of patient death – OnMedica (free) AND Low Nurse Staffing Increases Risk for Inpatient Death – Medscape (free registration required)

 

6 – Caring for the critically ill patients over 80: a narrative review – Annals  of Intensive Care (free)

 

7 – Cardiac Screening of Young Athletes: a Practical Approach to Sudden Cardiac Death Prevention – Current Treatment Options in Cardiovascular Medicine (free)

 

8 – Podcast: Delirium: Prevention, Diagnosis, and Treatment – JAMA (free)

 

9 – Association of estimated sleep duration and naps with mortality and cardiovascular events: a study of 116 632 people from 21 countries – European Heart Journal (free)

News Release: Too much or too little sleep linked to increased risk of cardiovascular disease and death – European Society of Cardiology (free)

Editorial: Sleep and cardiovascular risk: how much is too much of a good thing? (free)

 

10 – Association of Primary Care Consultation Patterns With Early Signs and Symptoms of Psychosis – JAMA Network Open (free)

Commentaries: Identifying Risk of Psychosis in a Primary Care Setting – JAMA Network Open (free) AND Spotting patients at risk for psychosis: 12 high-risk symptoms – Univadis (free registration required)

 


Perspective: The Ethics of Heritable Genome Editing

5 Dec, 2018 | 00:03h | UTC

The Ethics of Heritable Genome Editing: New Considerations in a Controversial Area – JAMA (free for a limited period)

Related: WHO looks at standards in ‘uncharted water’ of gene editing – Reuters (free) AND The CRISPR Baby Scandal Gets Worse by the Day – The Atlantic (free) AND We need a temporary moratorium on using gene editing to create babies – STAT (free) AND Is the CRISPR baby controversy the start of a terrifying new chapter in gene editing? – VOX (free) AND First CRISPR babies: six questions that remain – Nature (free) AND ‘I feel an obligation to be balanced.’ Noted biologist comes to defense of gene editing babies – Science (free)

 


Last Month in Oncology with Dr. Bishal Gyawali – November 2018

5 Dec, 2018 | 00:01h | UTC

Last Month in Oncology with Dr. Bishal Gyawali: November 2018 – eCancer News (free)

 


Study Suggests Statins are Overprescribed for Primary Prevention

5 Dec, 2018 | 00:05h | UTC

Finding the Balance Between Benefits and Harms When Using Statins for Primary Prevention of Cardiovascular Disease: A Modeling Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Statins may be significantly overprescribed for primary prevention, computer model suggests – ACP Internist (free) AND Benefits of Statins Only Exceed Harms at Higher 10-Year Risk Thresholds, Study Suggests – TCTMD (free) AND Higher Risk Thresholds May Be Needed for Starting Statins for Primary CVD Prevention, Study Suggests – NEJM Journal Watch (free) AND Statins are being overprescribed, study suggests – OnMedica (free)

 


Cohort Study: Body-Weight Fluctuation and Incident Diabetes Mellitus, Cardiovascular Disease, and Mortality

4 Dec, 2018 | 23:59h | UTC

Body-weight fluctuation and incident diabetes mellitus, cardiovascular disease, and mortality: a 16-year prospective cohort study – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)

Commentaries: Weight cycling is associated with a higher risk of death – The Endocrine Society (free) AND Study: Yo-yo diets can increase death risk – UPI (free)

 


Study: Fasting-Evoked En Route Hypoglycemia in Diabetes

5 Dec, 2018 | 00:02h | UTC

Fasting-Evoked En Route Hypoglycemia in Diabetes (FEEHD): An Overlooked Form of Hypoglycemia in Clinical Practice – International Journal of Endocrinology (free)

Commentary: Fasting for lab tests isn’t good for patients with diabetes – Michigan State University (free)

 


Review: Confounders of Severe Asthma

5 Dec, 2018 | 00:01h | UTC

Confounders of severe asthma: diagnoses to consider when asthma symptoms persist despite optimal therapy – World Allergy Organization Journal (free)

 


Study: Predictors of Dementia Misclassification When Using Brief Cognitive Assessments

5 Dec, 2018 | 00:00h | UTC

Predictors of dementia misclassification when using brief cognitive assessments – Neurology (free PDF)

Commentary: Study Finds Biases in Widely Used Dementia Identification Tests – University of Exeter (free) AND Primary Care Tests Flunk for Classifying Dementia – MedPage Today (free registration required) AND Brief Cognitive Exams Commonly Misdiagnose Dementia – NEJM Journal Watch (free)

 


Study: Validation of a Risk Scale for Patients with COPD Managed in the Emergency Department

4 Dec, 2018 | 23:55h | UTC

Clinical validation of a risk scale for serious outcomes among patients with chronic obstructive pulmonary disease managed in the emergency department – Canadian Medical Association Journal (free)

News Release: Tool identifies which patients with COPD are at risk of death, serious complications (free)

Commentary: Tool quickly identifies risk for deadly COPD complications – UPI (free)

 


Why the World is Becoming More Allergic to Food

4 Dec, 2018 | 23:58h | UTC

Why the world is becoming more allergic to food – BBC (free)

 


Perspective: Potential Risks and Benefits of Mental Health Screening of Physicians

4 Dec, 2018 | 23:56h | UTC

Potential Risks and Benefits of Mental Health Screening of Physicians – JAMA (free for a limited period)

 


Meta-Analysis: Aerosolized Antibiotics for Ventilator-Associated Pneumonia

4 Dec, 2018 | 23:47h | UTC

Aerosolized antibiotics for ventilator-associated pneumonia: a pairwise and Bayesian network meta-analysis – Critical Care (free)

 


Randomized Trial: Extended vs. Limited Lymph Node Dissection in Bladder Cancer Patients Undergoing Radical Cystectomy

4 Dec, 2018 | 23:48h | UTC

Extended Versus Limited Lymph Node Dissection in Bladder Cancer Patients Undergoing Radical Cystectomy: Survival Results from a Prospective, Randomized Trial – European Urology (free for a limited period)

 


Systematic Review: Bone Metastases from Colorectal Cancer

4 Dec, 2018 | 23:46h | UTC

Systematic review: Incidence, risk factors, survival and treatment of bone metastases from colorectal cancer – Journal of Bone Oncology (free)

 


Cohort Study: Long‐Term Outcome and Prognostic Factors of Complications in Thromboangiitis Obliterans (Buerger’s Disease)

4 Dec, 2018 | 23:45h | UTC

Long‐Term Outcome and Prognostic Factors of Complications in Thromboangiitis Obliterans (Buerger’s Disease): A Multicenter Study of 224 Patients – Journal of the American Heart Association (free)

Editorial: Thromboangiitis Obliterans: 110 Years Old and Little Progress Made (free)

 


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