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Research: This Is Your Brain Off Facebook

30 Jan, 2019 | 18:46h | UTC

This Is Your Brain Off Facebook – The New York Times (10 articles per month are free)

Original randomized trial, involving nearly 3000 individuals: The Welfare Effects of Social Media (free PDF)

“Expect the consequences to be fairly immediate: More in-person time with friends and family. Less political knowledge, but also less partisan fever. A small bump in one’s daily moods and life satisfaction. And, for the average Facebook user, an extra hour a day of downtime.”

 


Observational Study: β-Blocker Therapy Reduces the Risk for COPD Hospitalization

30 Jan, 2019 | 01:22h | UTC

β-Blocker Therapy and Risk of Chronic Obstructive Pulmonary Disease – A Danish Nationwide Study of 1·3 Million Individuals – EClinicalMedicine (free)

Commentary: Beta-Blocker Use Linked to Lower Risk for COPD Hospitalization – NEJM Journal Watch (free)

Related review and meta-analysis: Beta-blockers in patients with chronic obstructive disease and coexistent cardiac illnesses – COPD Research and Practice (free) AND Beta-blocker use and COPD mortality: a systematic review and meta-analysis – BMC Pulmonary Medicine (free)

Related observational studies: β-Blockers in COPD: A Cohort Study From the TONADO Research Program – CHEST (free) AND Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study – The BMJ (free)

 


Meta-Analysis: Prevalence of Cannabis Use Among Medical Students

30 Jan, 2019 | 01:10h | UTC

Prevalence of Cannabis Use Among Medical Students: A Systematic Review and Meta-analysis – Substance Abuse: Research and Treatment (free)

“1 in 3 medical students has used cannabis, whereas 8.8% were current users”

 


Study: Patients with Type 2 Diabetes Safely Switched from Analog to Less Costly Human Insulin

30 Jan, 2019 | 01:13h | UTC

Implementation of a Health Plan Program for Switching From Analogue to Human Insulin and Glycemic Control Among Medicare Beneficiaries With Type 2 Diabetes – JAMA (link to abstract – $ for full-text)

Commentary: Medicare Patients with Type 2 Diabetes Safely Switched From Analog to Human Insulin, JAMA Study Finds – AJMC (free)

Related: Meta-Analysis: Comparative Benefits and Harms of Basal Insulin Analogues for Type 2 Diabetes (link to abstract and commentaries) AND Retrospective Observational Study: Basal Insulin Analogs vs NPH Insulin for Type 2 Diabetes (link to abstract and commentaries)

“Patients with type 2 diabetes (T2D) enrolled in a CareMore Health Medicare Part D plan switched from analog to human insulin without significant loss of glycemic control while saving millions for themselves and for the health plan.: (from AJMC)

 


Ann Robinson’s Research Reviews, 29 January 2019

30 Jan, 2019 | 01:05h | UTC

Ann Robinson’s research reviews, 29 January 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Perspective: Promises, Promises, and Precision Medicine

30 Jan, 2019 | 00:56h | UTC

Promises, promises, and precision medicine – JCI: The Journal of Clinical Investigation (free)

Related: Representing a “revolution”: how the popular press has portrayed personalized medicine – Genetics in Medicine (free)

“Hype vs. reality. Vast disconnect between actual achievements of “precision medicine” and how portrayed in popular culture” (via @CaulfieldTim see Tweet)

 

Related Commentary on Twitter

 


Systematic Review: Point-of-Care Ultrasound in General Practice

30 Jan, 2019 | 00:58h | UTC

Point-of-Care Ultrasound in General Practice: A Systematic Review – Annals of Family Medicine (free)

 


FSRH Clinical Guidance: Combined Hormonal Contraception

30 Jan, 2019 | 00:47h | UTC

FSRH Clinical Guidance: Combined Hormonal Contraception – January 2019 – Faculty of Sexual and Reproductive Healthcare (free PDF)

Commentaries: No benefit to contraception pill intervals — according to guidance – OnMedica (free) AND Is it OK to take the pill every day without a break? – BBC News (free)

 


AHA Presidential Advisory: Urgent Challenges in Cardiovascular Disease

30 Jan, 2019 | 00:44h | UTC

Call to Action: Urgent Challenges in Cardiovascular Disease: A Presidential Advisory From the American Heart Association – Circulation (free PDF)

News Release: Lagging drug innovation, variations in quality of care and rising health care costs remain major barriers in fight against cardiovascular disease (free)

Commentaries: AHA issues ‘urgent’ call to action: 5 things to know – Cardiovascular Business (free) AND AHA Warns of Stagnating CVD Gains, Barriers to Access, and Dismal Drug Pipeline – TCTMD (free)

 


British Guideline for the Management of Neisseria Gonorrhoeae

30 Jan, 2019 | 00:51h | UTC

British Association for Sexual Health and HIV national guideline for the management of infection with Neisseria gonorrhoeae (2019) (free PDF)

Commentary: UK Gonorrhea Guideline Guards Against Antibiotic Resistance – MD Magazine (free)

Related Guideline: WHO Guidelines for the Treatment of Neisseria gonorrhoeae – World Health Organization (free)

 


Severe Asthma in Children: Evaluation and Management

29 Jan, 2019 | 22:00h | UTC

Severe asthma in children: Evaluation and management – Allergology International (free)

 


Trends of Liver Transplant for Alcohol-Associated Liver Disease

29 Jan, 2019 | 22:02h | UTC

National Trends and Long-term Outcomes of Liver Transplant for Alcohol-Associated Liver Disease in the United States – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: More liver transplants occurring in patients with alcohol-associated liver disease – ACP Gastroenterology (free) AND Alcohol destroyed their livers. Now, they’re increasingly getting new ones – CNN (free) AND Alcohol-Linked Disease Overtakes Hep C As Top Reason For Liver Transplant – Kaiser Health News (free)

 


Consensus Statement: Targeted Treatment of Primary Aldosteronism

29 Jan, 2019 | 22:01h | UTC

Targeted treatment of primary aldosteronism – The consensus of Taiwan Society of Aldosteronism – Journal of the Formosan Medical Association (free)

 


Review: Role of Decompressive Craniectomy in Ischemic Stroke

29 Jan, 2019 | 21:59h | UTC

Role of Decompressive Craniectomy in Ischemic Stroke – Frontiers in Neurology (free)

 


Central Nervous System Involvement in ANCA-Associated Vasculitis: What Neurologists Need to Know

29 Jan, 2019 | 21:55h | UTC

Central Nervous System Involvement in ANCA-Associated Vasculitis: What Neurologists Need to Know – Frontiers in Neurology (free)

 


Study: Low Recurrence Following Successful Ablation in Barrett’s Esophagus

29 Jan, 2019 | 21:51h | UTC

Timeline and location of recurrence following successful ablation in Barrett’s oesophagus: an international multicentre study – Gut (link to abstract – $ for full-text)

Commentary: Longer follow-up may not be advisable after complete remission of Barrett’s esophagus – ACP Gastroenterology (free)

 


Brazilian Guidelines for the Treatment of Systemic Autoimmune Myopathies

29 Jan, 2019 | 21:49h | UTC

Guidelines of the Brazilian Society of Rheumatology for the treatment of systemic autoimmune myopathies – Advances in Rheumatology (free)

 


Guide to Statistics and Methods: Using the E-Value to Assess the Potential Effect of Unmeasured Confounding in Observational Studies

29 Jan, 2019 | 21:46h | UTC

Guide to Statistics and Methods: Using the E-Value to Assess the Potential Effect of Unmeasured Confounding in Observational Studies – JAMA (free for a limited period)

 


Study: Assessment of Distal Radius Fracture Complications Among Adults 60 Years or Older

29 Jan, 2019 | 21:42h | UTC

Assessment of Distal Radius Fracture Complications Among Adults 60 Years or Older: A Secondary Analysis of the WRIST Randomized Clinical Trial – JAMA Network Open (free)

Invited Commentary: Wrist Fractures in Patients 60 Years or Older—To Plate or Cast? (free)

 


A Guide to Reproducibility in Preclinical Research

29 Jan, 2019 | 21:45h | UTC

A Guide to Reproducibility in Preclinical Research – Academic Medicine (free)

 


The Digital Drug: Internet Addiction Treatment Programs

29 Jan, 2019 | 21:41h | UTC

The digital drug: Internet addiction spawns U.S. treatment programs – Reuters (free)

Related: Gaming disorder – World Health Organization (free) AND Gaming addiction classified as mental health disorder by WHO – Reuters (free) AND WHO classifies ‘gaming disorder’ as mental health condition – CNN (free) AND Do You Have ‘Gaming Disorder,’ A Newly Recognized Mental Health Condition? – Forbes (free) AND Endless Gaming May Be a Bad Habit. That Doesn’t Make It a Mental Illness – The New York Times (10 articles per month are free) AND Gaming addiction as a mental disorder: it’s premature to pathologise players – The Conversation (free) AND Is ‘Internet Addiction’ Real? – NPR Health News (free)

 


Study: Screen Time and Children’s Performance on Developmental Test

29 Jan, 2019 | 18:16h | UTC

Association Between Screen Time and Children’s Performance on a Developmental Screening Test – JAMA Pediatrics (free for a limited period)

Commentaries: Expert reaction to study on use of screen time and child development – Science Media Centre (free) AND Too much toddler screen time tied to worse social, motor skills by kindergarten – Reuters (free) AND More screen time for toddlers is tied to poorer development a few years later, study says – CNN (free) AND Screen time ‘may harm toddlers’ – BBC (free) AND Screen time predicts delays in child development, says new research – The Conversation (free)

Related Guidelines: Media devices in pre-school children: the recommendations of the Italian pediatric society – Italian Journal of Pediatrics (free) AND Media and Young Minds – Recommendations from The American Academy of Pediatrics (free)

See also: Children, Adolescents and Screens: What We Know and What We Need To Learn (Pediatrics Supplement with free articles)

 


Atrial Fibrillation Guideline: 2019 AHA/ACC/HRS Focused Update

29 Jan, 2019 | 00:08h | UTC

2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation – Circulation (free PDF)

News Release: Updated treatment guidelines for atrial fibrillation recommend a new class of blood thinners to help prevent stroke – American Heart Association (free)

Commentaries: Focused Update of the AHA/ACC/HRS Atrial Fibrillation Guideline – American College of Cardiology (free) AND

 


Randomized Trial: Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia

29 Jan, 2019 | 00:05h | UTC

Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Prevention of Cognitive Impairment With Intensive Systolic Blood Pressure Control (free for a limited period)

Commentaries: Does intensive blood pressure control reduce dementia? – NIH News Releases (free) AND Intensive BP Control Helps Prevent Mild Cognitive Impairment – NEJM Journal Watch (free)

 

Related Commentary on Twitter

 


Tue, January 29 – 10 Stories of The Day!

29 Jan, 2019 | 00:23h | UTC

 

1 – 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation – Circulation (free PDF)

News Release: Updated treatment guidelines for atrial fibrillation recommend a new class of blood thinners to help prevent stroke – American Heart Association (free)

Commentaries: Focused Update of the AHA/ACC/HRS Atrial Fibrillation Guideline – American College of Cardiology (free) AND Popular blood thinner warfarin no longer recommended for most atrial fibrillation cases – CNN (free)

 

2 – European Practical and Patient-Centred Guidelines for Adult Obesity Management in Primary Care – Obesity Facts (free)

 

3 – Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Prevention of Cognitive Impairment With Intensive Systolic Blood Pressure Control (free for a limited period)

Commentary: Does intensive blood pressure control reduce dementia? – NIH News Releases (free)

 

4 – Human Papillomavirus Vaccine Effectiveness and Herd Protection in Young Women – Pediatrics (free)

Commentaries: Three Important Findings From a Study on HPV “Real World” Effectiveness – Pediatrics (free) AND HPV vaccine effective against infection and for herd immunity – 2 Minute Medicine (free)

Related Perspective on Herd Immunity: The Herd to the Rescue: How an Invisible Shield Can Keep us Healthy (free)

 

5 – Cost-effectiveness of urine-based tuberculosis screening in hospitalised patients with HIV in Africa: a microsimulation modelling study – The Lancet Global Health (free)

Commentaries: Costs of tuberculosis screening among inpatients with HIV – The Lancet Global Health (free) AND Using urine testing to diagnose TB in patients with HIV can save lives and be cost-effective – London School of Hygiene & Tropical Medicine (free)

 

6 – Perspective: The robot needs a human heart—why AI in medicine brings moral choices into focus – The BMJ Opinion (free)

 

7 – Patient-reported complications related to peripherally inserted central catheters: a multicentre prospective cohort study – BMJ Quality & Safety (free)

“Three in four patients that receive a PICC report a complication after discharge – yet very few are ever documented.” (via @vineet_chopra see Tweet)

 

8 – The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission report (free registration required)

Commentaries: Take on food industry to beat malnutrition and obesity, says report – The Guardian (free) AND Want to fix obesity and climate change at the same time? Make Big Food companies pay. – VOX (free) AND To fix climate change, fix the obesity and starvation epidemics, reports say – CNN (free)

“Holding people responsible for their obesity detracts attention from the obesogenic systems that produce obesity” (via @TheLancet see Tweet)

 

9 – Aerobic exercise for adult patients with major depressive disorder in mental health services: A systematic review and meta‐analysis – Depression & Anxiety (free)

Commentary: Aerobic exercise is an effective treatment for depression – NIHR Signal (free)

Related Study: Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study – JAMA Psychiatry (link to abstract – $ for full-text) AND Commentary: Exercise can reduce risk for depression, research shows – UPI (free)

 

10 – Physical activity, common brain pathologies, and cognition in community-dwelling older adults – Neurology (link to abstract – $ for full-text)

Commentaries: Daily Movement — Even Household Chores — May Boost Brain Health In Elderly – NPR (free) AND Keep Moving to Keep Brain Sharp in Old Age – U.S. News (free) AND Activity sharpens even dementia-affected brains, report suggests – The Guardian (free)

Related: Dose-response relationship between exercise and cognitive function in older adults with and without cognitive impairment: A systematic review and meta-analysis – PLOS One (free)

 


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