Archives
“Why I Decided to Provide Assisted Dying: It is Truly Patient Centred Care”
3 Feb, 2019 | 11:48h | UTCEssay: Why I decided to provide assisted dying: it is truly patient centred care – The BMJ (free)
Fri, February 1 – 10 Stories of The Day!
1 Feb, 2019 | 04:28h | UTC
1 – AACE/ACE Comprehensive Type 2 Diabetes Management Algorithm 2019 – Endocrine Practice (Free PDF and Slide Presentations)
Related Guidelines: ADA 2019 Standards of Medical Care in Diabetes (free supplement) AND Diabetes Canada 2018 clinical practice guidelines for the prevention and management of diabetes in Canada (free)
2 – Solutions for non-communicable disease prevention and control – The BMJ (free articles)
3 – PSA’s Medicine Safety: Take Care – Pharmaceutical Society of Australia (free PDF)
News Release: Problems with medicines behind 250,000 hospital admissions annually (free)
“The report reveals that 250,000 Australians are hospitalised each year, with another 400,000 presenting to emergency departments, as a result of medication errors, inappropriate use, misadventure and interactions. At least half of this could have been prevented.”
4 – Fatal flaws in clinical decision making – ANZ Journal of Surgery (free)
Commentary: Fatal flaws in clinical decision making – PSNet (free)
5 – Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women – Cochrane Library (free)
Summary: Iron supplements taken one, two or three times a week for preventing anaemia, and its consequences in menstruating women – Cochrane Library (free)
“In comparison with daily supplementation, the provision of iron supplements intermittently is probably as effective in preventing or controlling anemia”
6 – General health checks in adults for reducing morbidity and mortality from disease – Cochrane Library (free)
Summary: General health checks for reducing illness and mortality – Cochrane Library (free)
“General health checks are unlikely to be beneficial.”
9 – A.I. Could Worsen Health Disparities – The New York Times (free)
“In a health system riddled with inequity, we risk making dangerous biases automated and invisible.”
“The USPSTF recommends prophylactic ocular topical medication for all newborns to prevent gonococcal ophthalmia neonatorum. (A recommendation)”
Review: Benefits of Non‐invasive Ventilation in Acute Hypercapnic Respiratory Failure
3 Feb, 2019 | 11:30h | UTCBenefits of non‐invasive ventilation in acute hypercapnic respiratory failure – Respirology (free)
Related Guidelines: BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults – Thorax (free) AND The Japanese Respiratory Society Noninvasive Positive Pressure Ventilation (NPPV) Guidelines – Respiratory Investigation (free) AND Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline – European Respiratory Journal (free)
Related Reviews: Non‐invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease – Cochrane Library (free) AND Noninvasive ventilation in acute respiratory failure: which recipe for success? – European Respiratory Review (free)
Randomized Trial: Early Cooling Provides no Benefit Following Traumatic Brain Injury
3 Feb, 2019 | 11:42h | UTCEarly cooling provides no benefit following traumatic brain injury – NIHR Signal (free)
Original Study: Prophylactic Hypothermia Questioned After Severe Traumatic Brain Injury (link to abstract and commentary)
BMJ Collection: Solutions for Non-communicable Disease Prevention and Control
1 Feb, 2019 | 02:48h | UTCSolutions for non-communicable disease prevention and control – The BMJ (free articles)
Related Commentary on Twitter
Non-communicable diseases (NCDs) constitute a major global health challenge. This new collection examines the major obstacles to preventing and controlling these diseases and suggests scalable solutions https://t.co/mupvuqQoru @ajain247 @KamranAbbasi pic.twitter.com/lZ4b0mrW9e
— The BMJ (@bmj_latest) January 29, 2019
AACE/ACE Comprehensive Type 2 Diabetes Management Algorithm 2019
1 Feb, 2019 | 02:50h | UTCAACE/ACE Comprehensive Type 2 Diabetes Management Algorithm 2019 – Endocrine Practice (Free PDF and Slide Presentations)
Related Guidelines: ADA 2019 Standards of Medical Care in Diabetes (free supplement) AND Diabetes Canada 2018 clinical practice guidelines for the prevention and management of diabetes in Canada (free)
Study: Fatal Flaws in Clinical Decision Making
1 Feb, 2019 | 02:45h | UTCFatal flaws in clinical decision making – ANZ Journal of Surgery (free)
Commentary: Fatal flaws in clinical decision making – PSNet (free)
Systematic Review: Intermittent Iron Supplementation vs. Daily Supplementation for Preventing or Controlling Anemia
1 Feb, 2019 | 02:43h | UTCIntermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women – Cochrane Library (free)
Summary: Iron supplements taken one, two or three times a week for preventing anaemia, and its consequences in menstruating women – Cochrane Library (free)
“In comparison with daily supplementation, the provision of iron supplements intermittently is probably as effective in preventing or controlling anemia”
Review: Interstitial Lung Disease and Other Pulmonary Manifestations in Connective Tissue Diseases
1 Feb, 2019 | 02:40h | UTC
Report: Problems with Medicines Behind 250,000 Hospital Admissions Annually in Australia
1 Feb, 2019 | 02:46h | UTCPSA’s Medicine Safety: Take Care – Pharmaceutical Society of Australia (free PDF)
News Release: Problems with medicines behind 250,000 hospital admissions annually (free)
“The report reveals that 250,000 Australians are hospitalised each year, with another 400,000 presenting to emergency departments, as a result of medication errors, inappropriate use, misadventure and interactions. At least half of this could have been prevented.”
Systematic Review: General Health Checks for Reducing Illness and Mortality
1 Feb, 2019 | 02:41h | UTCGeneral health checks in adults for reducing morbidity and mortality from disease – Cochrane Library (free)
Summary: General health checks for reducing illness and mortality – Cochrane Library (free)
“General health checks are unlikely to be beneficial.”
The Alzheimer’s Disease Clinical Spectrum: Diagnosis and Management
1 Feb, 2019 | 02:38h | UTC
Opinion: A.I. Could Worsen Health Disparities
1 Feb, 2019 | 02:36h | UTCA.I. Could Worsen Health Disparities – The New York Times (free)
“In a health system riddled with inequity, we risk making dangerous biases automated and invisible.”
USPSTF Statement: Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum
1 Feb, 2019 | 02:35h | UTC“The USPSTF recommends prophylactic ocular topical medication for all newborns to prevent gonococcal ophthalmia neonatorum. (A recommendation)”
Thu, January 31 – 10 Stories of The Day!
31 Jan, 2019 | 01:24h | UTC
1 – Oral versus Intravenous Antibiotics for Bone and Joint Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Related Trial: Partial Oral vs. Intravenous Antibiotic Treatment of Endocarditis (link to abstract and commentaries)
Commentary: Oral antibiotics may work for some ortho, heart infections – CIDRAP (free)
“Oral antibiotic therapy was noninferior to intravenous antibiotic therapy when used during the first 6 weeks for complex orthopedic infection, as assessed by treatment failure at 1 year.”
2 – A Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy – New England Journal of Medicine (link to abstract – $ for full-text)
Editorial: The Dangerous Flavors of E-Cigarettes (free)
Commentaries: E-cigarettes more effective than nicotine replacement therapies, finds major trial – Queen Mary University of London (free) AND UK study shows e-cigarettes help adult smokers quit, but US experts urge caution – CNN (free) AND E-Cigarettes Are Effective at Helping Smokers Quit, a Study Says – The New York times (10 articles per month are free) AND E-cigarettes ‘much better for quitting smoking’ – BBC (free) AND Study Found Vaping Beat Traditional Smoking-Cessation Options – NPR (free)
3 – Are Probiotics Money Down the Toilet? Or Worse? – JAMA (free for a limited period)
Related: Randomized Trials: Probiotics Ineffective Against Gastroenteritis (link to abstract and commentaries) AND Perspective: The Problem with Probiotics (free commentaries) AND Probiotics: Does the Evidence Match the Hype? (link to abstract and commentaries) AND Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries)
Commentary: Breakfast—the most important meal of the day? – The BMJ Opinion (free)
5 – 10 myths about furosemide – Intensive Care Medicine (free)
Note: if the above link is paywalled, try this one
6 – State of the Art Review: Peripartum cardiomyopathy – The BMJ (free for a limited period)
Related Reviews: Peripartum Cardiomyopathy – Circulation (free) AND Practical management of peripartum cardiomyopathy – Korean Journal of Internal Medicine (free) AND A contemporary review of peripartum cardiomyopathy – Clinical Medicine (free)
8 – Debates in sepsis – ACP Hospitalist (free)
Related: Point and Counterpoint: Should the Surviving Sepsis Campaign Guidelines Be Retired? (free commentaries) AND The 2018 Surviving Sepsis Campaign’s Treatment Bundle: When Guidelines Outpace the Evidence Supporting Their Use (free commentaries)
9 – Why are so many people still dying from snake bites? – BBC (free)
10 – This Is Your Brain Off Facebook – The New York Times (10 articles per month are free)
Original randomized trial, involving nearly 3000 individuals: The Welfare Effects of Social Media (free PDF)
“Expect the consequences to be fairly immediate: More in-person time with friends and family. Less political knowledge, but also less partisan fever. A small bump in one’s daily moods and life satisfaction. And, for the average Facebook user, an extra hour a day of downtime.”
Randomized Trial: Oral versus Intravenous Antibiotics for Bone and Joint Infection
30 Jan, 2019 | 23:56h | UTCOral versus Intravenous Antibiotics for Bone and Joint Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Related Trial: Partial Oral vs. Intravenous Antibiotic Treatment of Endocarditis (link to abstract and commentaries)
Commentary: Oral antibiotics may work for some ortho, heart infections – CIDRAP (free)
Related Commentary on Twitter
In this trial, 1054 participants with complex orthopedic infections were assigned to receive either oral or intravenous antibiotics for the first 6 weeks of treatment. At 1 year, oral therapy was noninferior to intravenous therapy.
— NEJM (@NEJM) January 30, 2019
10 Myths About Frusemide
30 Jan, 2019 | 23:31h | UTC10 myths about frusemide – Intensive Care Medicine (free)
Note: if the above link is paywalled, try this one
Randomized Trial: E-Cigarettes vs. Nicotine-Replacement Therapy
30 Jan, 2019 | 23:35h | UTCA Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy – New England Journal of Medicine (link to abstract – $ for full-text)
Editorial: The Dangerous Flavors of E-Cigarettes (free)
Commentaries: E-cigarettes more effective than nicotine replacement therapies, finds major trial – Queen Mary University of London (free) AND UK study shows e-cigarettes help adult smokers quit, but US experts urge caution – CNN (free) AND E-Cigarettes Are Effective at Helping Smokers Quit, a Study Says – The New York times (10 articles per month are free) AND E-cigarettes ‘much better for quitting smoking’ – BBC (free) AND Study Found Vaping Beat Traditional Smoking-Cessation Options – NPR (free)
Related Commentary on Twitter
Trial finds e-cigarettes more effective than nicotine-replacement therapy with respect to the 1-year abstinence rate (18% vs. 10%). Throat or mouth irritation was more common with e-cigarettes, and nausea was more common with nicotine-replacement. https://t.co/cyEnDP630v pic.twitter.com/1je5vN87ru
— NEJM (@NEJM) January 30, 2019
Perspective: Are Probiotics Money Down the Toilet? Or Worse?
30 Jan, 2019 | 23:34h | UTCAre Probiotics Money Down the Toilet? Or Worse? – JAMA (free for a limited period)
Related: Randomized Trials: Probiotics Ineffective Against Gastroenteritis (link to abstract and commentaries) AND Perspective: The Problem with Probiotics (free commentaries) AND Probiotics: Does the Evidence Match the Hype? (link to abstract and commentaries) AND Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries)
Meta-Analysis: Effect of Breakfast on Weight and Energy Intake
30 Jan, 2019 | 23:33h | UTCCommentary: Breakfast—the most important meal of the day? – The BMJ Opinion (free)
State of the Art Review: Peripartum cardiomyopathy
30 Jan, 2019 | 23:32h | UTCState of the Art Review: Peripartum cardiomyopathy – The BMJ (free for a limited period)
Related Reviews: Peripartum Cardiomyopathy – Circulation (free) AND Practical management of peripartum cardiomyopathy – Korean Journal of Internal Medicine (free) AND A contemporary review of peripartum cardiomyopathy – Clinical Medicine (free)
Perspective: Debates in Sepsis
30 Jan, 2019 | 23:20h | UTCDebates in sepsis – ACP Hospitalist (free)
Related: Point and Counterpoint: Should the Surviving Sepsis Campaign Guidelines Be Retired? (free commentaries) AND The 2018 Surviving Sepsis Campaign’s Treatment Bundle: When Guidelines Outpace the Evidence Supporting Their Use (free commentaries)
Why Are So Many People Still Dying from Snake Bites?
30 Jan, 2019 | 23:15h | UTCWhy are so many people still dying from snake bites? – BBC (free)
ESC Position Statement: Depression and Coronary Heart Disease
30 Jan, 2019 | 23:30h | UTC
Wed, January 30 – 10 Stories of The Day!
30 Jan, 2019 | 01:33h | UTC
Commentary: Beta-Blocker Use Linked to Lower Risk for COPD Hospitalization – NEJM Journal Watch (free)
Related review and meta-analysis: Beta-blockers in patients with chronic obstructive disease and coexistent cardiac illnesses – COPD Research and Practice (free) AND Beta-blocker use and COPD mortality: a systematic review and meta-analysis – BMC Pulmonary Medicine (free)
Related observational studies: β-Blockers in COPD: A Cohort Study From the TONADO Research Program – CHEST (free) AND Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study – The BMJ (free)
2 – Implementation of a Health Plan Program for Switching From Analogue to Human Insulin and Glycemic Control Among Medicare Beneficiaries With Type 2 Diabetes – JAMA (link to abstract – $ for full-text)
Commentary: Medicare Patients with Type 2 Diabetes Safely Switched From Analog to Human Insulin, JAMA Study Finds – AJMC (free)
Related: Meta-Analysis: Comparative Benefits and Harms of Basal Insulin Analogues for Type 2 Diabetes (link to abstract and commentaries) AND Retrospective Observational Study: Basal Insulin Analogs vs NPH Insulin for Type 2 Diabetes (link to abstract and commentaries)
“Patients with type 2 diabetes (T2D) enrolled in a CareMore Health Medicare Part D plan switched from analog to human insulin without significant loss of glycemic control while saving millions for themselves and for the health plan.” (from AJMC)
“1 in 3 medical students has used cannabis, whereas 8.8% were current users”
4 – Ann Robinson’s research reviews, 29 January 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
5 – Point-of-Care Ultrasound in General Practice: A Systematic Review – Annals of Family Medicine (free)
6 – Perspective: Promises, promises, and precision medicine – JCI The Journal of Clinical Investigation (free)
Related: Representing a “revolution”: how the popular press has portrayed personalized medicine – Genetics in Medicine (free)
“Hype vs. reality. Vast disconnect between actual achievements of “precision medicine” and how portrayed in popular culture” (via @CaulfieldTim see Tweet)
“Nearly two decades after the first predictions of dramatic success, we find no impact of the human genome project on the population’s life expectancy or any other public health measure.” (via @MuinJKhoury see Tweet)
Commentary: UK Gonorrhea Guideline Guards Against Antibiotic Resistance – MD Magazine (free)
Related Guideline: WHO Guidelines for the Treatment of Neisseria gonorrhoeae – World Health Organization (free)
Commentaries: No benefit to contraception pill intervals — according to guidance – OnMedica (free) AND Is it OK to take the pill every day without a break? – BBC News (free)
News Release: Lagging drug innovation, variations in quality of care and rising health care costs remain major barriers in fight against cardiovascular disease (free)
Commentaries: AHA issues ‘urgent’ call to action: 5 things to know – Cardiovascular Business (free) AND AHA Warns of Stagnating CVD Gains, Barriers to Access, and Dismal Drug Pipeline – TCTMD (free)
10 – Association Between Screen Time and Children’s Performance on a Developmental Screening Test – JAMA Pediatrics (free for a limited period)
Commentaries: Expert reaction to study on use of screen time and child development – Science Media Centre (free) AND Too much toddler screen time tied to worse social, motor skills by kindergarten – Reuters (free) AND More screen time for toddlers is tied to poorer development a few years later, study says – CNN (free) AND Screen time ‘may harm toddlers’ – BBC (free) AND Screen time predicts delays in child development, says new research – The Conversation (free)
Related Guidelines: Media devices in pre-school children: the recommendations of the Italian pediatric society – Italian Journal of Pediatrics (free) AND Media and Young Minds – Recommendations from The American Academy of Pediatrics (free)
See also: Children, Adolescents and Screens: What We Know and What We Need To Learn (Pediatrics Supplement with free articles)