Archives
Viewpoint: Patients and Physicians in the Era of Modern Cancer Care
16 Feb, 2019 | 14:21h | UTCPatients and Physicians in the Era of Modern Cancer Care – JAMA (free for a limited period)
Randomized Trial: Early Use of Norepinephrine in Septic Shock Resuscitation
16 Feb, 2019 | 13:58h | UTCEarly Use of Norepinephrine in Septic Shock Resuscitation (CENSER) : A Randomized Trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
See Commentary by Wellington ICU
“This is a promising result, and more and larger studies are needed to confirm the findings.” (from Wellington ICU)
Systematic Review: Palliative Care Initiation in Pediatric Oncology Patients
16 Feb, 2019 | 14:02h | UTCPalliative care initiation in pediatric oncology patients: A systematic review – Cancer Medicine (free)
Chinese Guidelines on the Management of Ascites and its Related Complications in Cirrhosis
16 Feb, 2019 | 13:49h | UTCNote: if the above link is not working, try this one
Related Guidelines: Evidence-based clinical practice guidelines for liver cirrhosis 2015 – Journal of Gastroenterology (free) AND Management of Adult Patients with Ascites Due to Cirrhosis: Update 2012 – American Association for the Study of Liver Diseases (free PDF) EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis (free) AND KASL clinical practice guidelines for liver cirrhosis: Ascites and related complications – Clinical and Molecular Hepatology (free) AND Cirrhosis in Over 16s: Assessment and Management – National Institute for Health and Care Excellence (free)
Fri, February 15 – 10 Stories of The Day!
15 Feb, 2019 | 01:23h | UTC
1 – Computer vs. patient: Fighting for residents’ attention – SCOPE (free)
Original Article: Characterizing electronic health record usage patterns of inpatient medicine residents using event log data – PLOS One (free)
Related: Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians (free) AND Date Night with the EHR – NEJM Catalyst (free) AND How Tech Can Turn Doctors into Clerical Workers – The New York Times Magazine (10 articles per month are free) AND To Combat Physician Burnout and Improve Care, Fix the Electronic Health Record – Harvard Business Review (a few articles per month are free) AND “It is like texting at the dinner table”: a qualitative analysis of the impact of electronic health records on patient–physician interaction in hospitals – Journal of Innovation in Health Informatics (free) AND A Time-Motion Study of Primary Care Physicians’ Work in the Electronic Health Record Era – Family Medicine (free) AND Care-Centered Clinical Documentation in the Digital Environment: Solutions to Alleviate Burnout – National Academy of Medicine (free) AND Electronic Health Record Usability Issues and Potential Contribution to Patient Harm – JAMA (free)
2 – Head to Head: Should we screen for atrial fibrillation? – The BMJ (free)
Commentary: Should we screen people for irregular heartbeat? – The BMJ, via ScienceDaily (free)
Related: USPSTF Statement: Screening with Resting or Exercise Electrocardiography (ECG) Not Recommended (free Guideline and commentaries) AND Wearable technology to screen for atrial fibrillation: does it raise more questions than it answers? (free commentaries) AND Get Ready For A Tsunami Of ECGs (free commentaries)
Related Cochrane Review (just published): Pregabalin for neuropathic pain in adults – Cochrane Library (free) and Commentary: Pregabalin for neuropathic pain: balancing benefits and harms – Evidently Cochrane (free)
4 – Guideline Synopsis: Diagnosis and Management of Infectious Diarrhea – JAMA (free)
Original Guideline: 2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea (free)
Related Guidelines: Guidelines for the prevention and treatment of travelers’ diarrhea: a graded expert panel report (free) AND Guidelines for the Investigation of Chronic Diarrhoea in Adults: British Society of Gastroenterology (free)
Related Report: Global Burden of Diarrhea (free report and commentaries)
5 – Next-Generation Sequencing of Infectious Pathogens – JAMA (free)
Related: Advanced Molecular Detection (AMD) – Centers for Disease Control and Prevention (free resources) AND Next Generation Sequencing of Infectious Pathogens in Public Health and Clinical Practice – JAMA (free podcast) AND Integrating Advanced Molecular Technologies into Public Health – Journal of Clinical Microbiology (free) AND Next-generation sequencing technologies and their application to the study and control of bacterial infections – Clinical Microbiology and Infection (free) AND Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis – Clinical Microbiology Reviews (free)
6 – Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Study: At-home decolonization cuts MRSA, other infections – CIDRAP (free) AND Outpatient cleaning regimen cuts MRSA infection by a third – News Medical (free) AND Cleaning routine shows promise in curbing superbug infection – Associated Press (free)
Worth reading.
Related: Guideline: Deprescribing Benzodiazepines (free guideline and resources) AND Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
Commentaries: Diet drinks may be associated with strokes among post-menopausal women – American Heart Association (free) AND Post-menopausal women who drink diet soda have increased stroke risk – UPI (free) AND Artificially Sweetened Drinks Linked to Stroke, Heart Disease – NEJM Journal Watch (free)
10 – Association of Behavior in Boys From Low Socioeconomic Neighborhoods With Employment Earnings in Adulthood – JAMA Pediatrics (free for a limited period)
Commentaries: Inattention in Low-Income Boys Tied to Lesser Earnings in Adulthood – PsychCentral (free) AND Low-income boys’ inattention in kindergarten associated with lower earnings 30 years later – Carnegie Mellon University (free) AND Behavior at Age 6 May Predict Adult Income – The New York Times (10 articles per month are free)
Meta-Analysis: Fever Control in Critically Ill Adults
16 Feb, 2019 | 13:54h | UTCNote: if the above link is not working, try this one
“Our findings do not support the hypothesis that more active fever management increases survival compared with less active fever management overall or in patients with limited physiological reserves.”
Computer vs. Patient: Fighting for Residents’ Attention
15 Feb, 2019 | 01:20h | UTCComputer vs. patient: Fighting for residents’ attention – SCOPE (free)
Original Article: Characterizing electronic health record usage patterns of inpatient medicine residents using event log data – PLOS One (free)
Related: Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians (free) AND Date Night with the EHR – NEJM Catalyst (free) AND How Tech Can Turn Doctors into Clerical Workers – The New York Times Magazine (10 articles per month are free) AND To Combat Physician Burnout and Improve Care, Fix the Electronic Health Record – Harvard Business Review (a few articles per month are free) AND “It is like texting at the dinner table”: a qualitative analysis of the impact of electronic health records on patient–physician interaction in hospitals – Journal of Innovation in Health Informatics (free) AND A Time-Motion Study of Primary Care Physicians’ Work in the Electronic Health Record Era – Family Medicine (free) AND Care-Centered Clinical Documentation in the Digital Environment: Solutions to Alleviate Burnout – National Academy of Medicine (free) AND Electronic Health Record Usability Issues and Potential Contribution to Patient Harm – JAMA (free)
Meta-Analysis: Benefits and Harms of Pregabalin in the Management of Neuropathic Pain
15 Feb, 2019 | 00:51h | UTCRelated Cochrane Review (just published): Pregabalin for neuropathic pain in adults – Cochrane Library (free) and Commentary: Pregabalin for neuropathic pain: balancing benefits and harms – Evidently Cochrane (free)
BMJ Head to Head: Should We Screen for Atrial fibrillation?
15 Feb, 2019 | 00:52h | UTCShould we screen for atrial fibrillation? – The BMJ (free)
Commentary: Should we screen people for irregular heartbeat? – The BMJ, via ScienceDaily (free)
Related: USPSTF Statement: Screening with Resting or Exercise Electrocardiography (ECG) Not Recommended (free Guideline and commentaries) AND Wearable technology to screen for atrial fibrillation: does it raise more questions than it answers? (free commentaries) AND Get Ready For A Tsunami Of ECGs (free commentaries)
JAMA Clinical Guideline Synopsis: Diagnosis and Management of Infectious Diarrhea
15 Feb, 2019 | 00:48h | UTCGuideline Synopsis: Diagnosis and Management of Infectious Diarrhea – JAMA (free)
Original Guideline: 2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea (free)
Related Guidelines: Guidelines for the prevention and treatment of travelers’ diarrhea: a graded expert panel report (free) AND Guidelines for the Investigation of Chronic Diarrhoea in Adults: British Society of Gastroenterology (free)
Related Report: Global Burden of Diarrhea (free report and commentaries)
Next-Generation Sequencing of Infectious Pathogens
15 Feb, 2019 | 00:47h | UTCNext-Generation Sequencing of Infectious Pathogens – JAMA (free)
Related: Advanced Molecular Detection (AMD) – Centers for Disease Control and Prevention (free resources) AND Next Generation Sequencing of Infectious Pathogens in Public Health and Clinical Practice – JAMA (free podcast) AND Integrating Advanced Molecular Technologies into Public Health – Journal of Clinical Microbiology (free) AND Next-generation sequencing technologies and their application to the study and control of bacterial infections – Clinical Microbiology and Infection (free) AND Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis – Clinical Microbiology Reviews (free)
Randomized Trial: Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers
15 Feb, 2019 | 00:45h | UTCDecolonization to Reduce Postdischarge Infection Risk among MRSA Carriers – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Study: At-home decolonization cuts MRSA, other infections – CIDRAP (free) AND Outpatient cleaning regimen cuts MRSA infection by a third – News Medical (free) AND Cleaning routine shows promise in curbing superbug infection – Associated Press (free)
Worth reading. The most devastating critique of medicine since Medical Nemesis by Ivan Illich in 1975
15 Feb, 2019 | 00:43h | UTC
Study: Association of Behavior in Boys with Employment Earnings in Adulthood
15 Feb, 2019 | 00:32h | UTCAssociation of Behavior in Boys From Low Socioeconomic Neighborhoods With Employment Earnings in Adulthood – JAMA Pediatrics (free for a limited period)
Commentaries: Inattention in Low-Income Boys Tied to Lesser Earnings in Adulthood – PsychCentral (free) AND Low-income boys’ inattention in kindergarten associated with lower earnings 30 years later – Carnegie Mellon University (free) AND Behavior at Age 6 May Predict Adult Income – The New York Times (10 articles per month are free)
Deprescribing Benzodiazepine Receptor Agonists Taken for Insomnia
15 Feb, 2019 | 00:39h | UTCRelated: Guideline: Deprescribing Benzodiazepines (free guideline and resources) AND Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
https://twitter.com/JustinLeeMD/status/1095881022330322944?s=03
Observational Study Suggests Artificially Sweetened Beverages May Increase the Risk of Stroke, Coronary Heart Disease, and All-Cause Mortality
15 Feb, 2019 | 00:35h | UTCCommentaries: Diet drinks may be associated with strokes among post-menopausal women – American Heart Association (free) AND Post-menopausal women who drink diet soda have increased stroke risk – UPI (free) AND Artificially Sweetened Drinks Linked to Stroke, Heart Disease – NEJM Journal Watch (free)
NICE Quality Standard: Serious Eye Disorders
14 Feb, 2019 | 17:11h | UTCQuality Standard: Serious Eye Disorders – National Institute for Health and Care Excellence (free)
Related Guideline: Glaucoma: diagnosis and management – National Institute for Health and Care Excellence (free)
Thu, February 14 – 10 Stories of The Day!
14 Feb, 2019 | 02:03h | UTC
Commentary: Absence of hypertension, overweight and smoking results in 9 disease-free years and prolonged life expectancy of 6 years – PACE-CME (free)
2 – Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Ibuprofen may be a ‘reasonable option’ for analgesia after hip replacement – medwire News (free) AND Acetaminophen Plus Ibuprofen Linked to Less Morphine Use After Hip Arthroplasty – NEJM Journal Watch (free) AND Paracetamol plus ibuprofen significantly reduces post-operative morphine use in total hip arthroplasty patients – 2 Minute Medicine (free)
3 – Does This Patient Have a Severe Snake Envenomation? The Rational Clinical Examination Systematic Review – JAMA Surgery (free for a limited period)
Related: Global Mapping of Vulnerability to Snakebite Envenoming (free study and commentaries) AND Why Are So Many People Still Dying from Snake Bites? (free) AND Snakebite finally makes a WHO list of top global health priorities (free) AND Snakebites Make The List Of ‘Neglected Tropical Diseases’ (free)
Commentary: Permissive hypotensive resuscitation in patients with traumatic hemorrhagic shock – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)
5 – Zackary Berger’s weekly research reviews, 13 February 2019 – The BMJ Opinion (free)
7 – Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Expert reaction to cannabis use in adolescents and risk of depression, anxiety and suicidality – Science Media Centre (free) AND Increased depression and suicidal behavior risk for young cannabis users – McGill University Health Centre (free) AND Cannabis smoking in teenage years linked to adulthood depression – The Guardian (free) AND Teen cannabis use linked to higher risk of adolescent depression – Reuters (free)
8 – Breast cancer deaths averted over 3 decades – Cancer (free)
Commentaries: Treatment Advances Averted More Than Half a Million Breast Cancer Deaths Over 3 Decades – AJMC (free) AND Recent Decrease in Deaths Attributable to Breast Cancer in the United States – The ASCO Post (free)
9 – Association of Left Ventricular Ejection Fraction and Symptoms With Mortality After Elective Noncardiac Surgery Among Patients With Heart Failure – JAMA (link to abstract – $ for full-text)
Commentaries: Symptomatic and non-symptomatic heart failure associated with increased postoperative mortality in non-cardiac elective surgery – 2 Minute Medicine (free) AND LVEF, HF Symptoms, and Mortality After Surgery – American College of Cardiology (free)
10 – Association of dietary macronutrient composition and non-alcoholic fatty liver disease in an ageing population: the Rotterdam Study – Gut (link to abstract – $ for full-text)
Commentary: Eating lots of meat tied to higher risk of liver disease – Reuters (free) AND Diet Heavy in Meat Boosts NAFLD Risk – MedPage Today (free registration required)
Study: Absence of Smoking, Hypertension, and Overweight Linked to a Prolonged Life Expectancy of 6 Years and 9 Years of Disease-free Life Expectancy
14 Feb, 2019 | 01:58h | UTCCommentary: Absence of hypertension, overweight and smoking results in 9 disease-free years and prolonged life expectancy of 6 years – PACE-CME (free)
Related Commentary on Twitter
📣Absence of #hypertension, #overweight & #smoking results in 9 disease-free years and prolonged #lifeexpectancy of 6 years.
📍PLoS Med 16(2): e1002741.vía @PACEcme
Commentary:
🔗https://t.co/S5vnrgYRudOpen access:
🔗https://t.co/GfNdFxEg0z@SEMERGENap @SEHLELHA140_90 pic.twitter.com/hCI1DsZS1h— Vicente Pallares (@vic_pallares) February 13, 2019
Randomized Trial: Effects of Paracetamol + Ibuprofen vs Either Alone on Morphine Consumption After Total Hip Arthroplasty
14 Feb, 2019 | 01:50h | UTCEffect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Ibuprofen may be a ‘reasonable option’ for analgesia after hip replacement – medwire News (free) AND Acetaminophen Plus Ibuprofen Linked to Less Morphine Use After Hip Arthroplasty – NEJM Journal Watch (free) AND Paracetamol plus ibuprofen significantly reduces post-operative morphine use in total hip arthroplasty patients – 2 Minute Medicine (free)
Does This Patient Have a Severe Snake Envenomation?
14 Feb, 2019 | 01:48h | UTCDoes This Patient Have a Severe Snake Envenomation? The Rational Clinical Examination Systematic Review – JAMA Surgery (free for a limited period)
Related: Global Mapping of Vulnerability to Snakebite Envenoming (free study and commentaries) AND Why Are So Many People Still Dying from Snake Bites? (free) AND Snakebite finally makes a WHO list of top global health priorities (free) AND Snakebites Make The List Of ‘Neglected Tropical Diseases’ (free)
Meta-Analysis: Hypotensive Resuscitation in Patients with Traumatic Hemorrhagic Shock
14 Feb, 2019 | 01:45h | UTCCommentary: Permissive hypotensive resuscitation in patients with traumatic hemorrhagic shock – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)
Medication Adherence: Scope of the Problem, Ways to Measure, Ways to Improve, and the Role of the Pharmacist
14 Feb, 2019 | 01:29h | UTC
Zackary Berger’s weekly research reviews – 13 February 2019
14 Feb, 2019 | 01:30h | UTCZackary Berger’s weekly research reviews, 13 February 2019 – The BMJ Opinion (free)
Study: High Animal Protein Intake Linked to Non-alcoholic Fatty Liver Disease
14 Feb, 2019 | 01:16h | UTCAssociation of dietary macronutrient composition and non-alcoholic fatty liver disease in an ageing population: the Rotterdam Study – Gut (link to abstract – $ for full-text)
Commentary: Eating lots of meat tied to higher risk of liver disease – Reuters (free) AND Diet Heavy in Meat Boosts NAFLD Risk – MedPage Today (free registration required)