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Guidelines for the Provision of Intensive Care Services

28 Jun, 2019 | 07:46h | UTC

Guidelines for the Provision of Intensive Care Services – Edition 2 – Intensive Care Society (free PDF)

 


ESC Position Statement: Pathophysiology, Diagnosis and Management of Peripartum Cardiomyopathy

28 Jun, 2019 | 07:47h | UTC

Pathophysiology, diagnosis and management of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on peripartum cardiomyopathy – European Journal of Heart Failure (free)

Related Reviews: Peripartum Cardiomyopathy – Circulation (free) AND Practical management of peripartum cardiomyopathy – Korean Journal of Internal Medicine (free) AND A contemporary review of peripartum cardiomyopathy – Clinical Medicine (free) AND State of the Art Review: Peripartum cardiomyopathy – The BMJ (free)

 


Mass Drug Administration for Scabies

28 Jun, 2019 | 07:43h | UTC

Mass Drug Administration for Scabies — 2 Years of Follow-up – New England Journal of Medicine (free)

Commentaries: New Australian-Pacific scabies treatment has lasting results, study finds – Murdoch Childrens Research Institute (free) AND Scabies Means Misery. This Pill Can End It. – The New York Times (10 articles per month are free)

Related Study: Mass Drug Administration Reduces Scabies Cases by 90% in Solomon Islands’ Communities (free)

 


Serial High-Sensitivity Troponin Measurements to Estimate the Probability of Myocardial Infarction

28 Jun, 2019 | 07:45h | UTC

Application of High-Sensitivity Troponin in Suspected Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: High-Sensitivity Troponin in Suspected MI – American College of Cardiology (free) AND Risk Stratification Using Serial High-Sensitivity Troponin Measurements – NEJM Journal Watch (free)

See also: Compass MI Calculator

 


Perspective: Challenging the Resistance to Palliative Care

28 Jun, 2019 | 07:42h | UTC

Survey Snapshot: Challenging the Resistance to “Palliative” – NEJM Catalyst (free)

 


Study Review: Antiretroviral Treatment can Reduce the Risk of HIV Transmission Between Male Partners to ‘Zero’

28 Jun, 2019 | 07:40h | UTC

Antiretroviral treatment can reduce the risk of HIV transmission between male partners to ‘zero’ – NIHR Signal (free)

Original Study: Undetectable = Untransmittable: Risk of HIV Transmission in Serodifferent Gay Couples (free study and commentaries)

Related: Systematic Review: Negligible Risk of Transmitting HIV During Sex When Viral Load is Suppressed (free study and commentaries) AND UNAIDS Explainer: UNDETECTABLE = UNTRANSMITTABLE (free)

 


Study: Inpatient Physician Continuity Associated with Speedier Patient Discharge

28 Jun, 2019 | 07:38h | UTC

The Influence of Inpatient Physician Continuity on Hospital Discharge – Journal of General Internal Medicine (free)

Commentary: Inpatient physician continuity associated with speedier discharge at one hospital – ACP Hospitalist (free)

 


[Abstract Only] Study: Triclosan Exposure Linked to Osteoporosis in Women

28 Jun, 2019 | 07:35h | UTC

Association between urinary triclosan with bone mass density and osteoporosis in the US adult women, 2005-2010 – The Journal of Clinical Endocrinology & Metabolism (free)

Commentaries: Triclosan Exposure May Lower Bone Mineral Density in Women – MPR (free) AND Osteoporosis: Investigating the role of a common antibacterial chemical – Medical News Today (free) AND Chemical in soaps, hand sanitizers tied to osteoporosis – Reuters (free)

 


Study: Dietary Carbohydrate Restriction Improves Metabolic Syndrome Independent of Weight Loss

28 Jun, 2019 | 07:36h | UTC

Dietary carbohydrate restriction improves metabolic syndrome independent of weight loss – JCI Insight (free)

Commentary: Low-carb diet may reduce diabetes risk independent of weight loss – Ohio State University (free)

 


Thu June 27 – 10 Stories of The Day!

27 Jun, 2019 | 10:55h | UTC

 

1 – Diagnosing and managing work‐related mental health conditions in general practice: new Australian clinical practice guidelines – The Medical Journal of Australia (free)

 

2 – Same‐Day Discharge After Elective Percutaneous Coronary Interventions in Ontario, Canada – Journal of the American Heart Association (free)

Editorial: Same‐Day Discharge After Elective Uncomplicated Percutaneous Coronary Interventions (free)

Commentaries: Same-Day Discharge Safe After Elective PCI, Canadian Study Affirms – TCTMD (free) AND New study suggests same-day discharge after non-surgical heart procedure could save money and free up hospital beds – ICES (free)

Related Study: Same-Day Discharge After Elective PCI Seems Safe and Reduce Costs (free)

 

3 – New Guidelines Aim to Expand Palliative Care Beyond Specialists – JAMA (free for a limited period)

Audio Summary: New Guidelines Aim to Expand Palliative Care Beyond Specialists (free)

Original Guideline: Clinical Practice Guidelines for Quality Palliative Care (free article and commentaries)

Related: Building a Better Death, One Conversation at a Time – JAMA (free for a limited period)

 

4 – Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentaries: Vaccination programs substantially reduce HPV infections and precancerous cervical lesions – Laval University (free) AND Hopes raised of cervical cancer eradication – BBC (free) AND Study shows major real-world impact of cervical cancer vaccines – Reuters (free)

 

5 – Amisulpride for the Rescue Treatment of Postoperative Nausea or Vomiting in Patients Failing Prophylaxis: A Randomized, Placebo-controlled Phase III Trial – Anesthesiology (free)

Related Study: Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Amisulpride as Treatment of Established Postoperative Nausea and Vomiting in Patients Who Have Had No Prior Prophylaxis (link to abstract)

 

6 – Performance of a Deep-Learning Algorithm vs Manual Grading for Detecting Diabetic Retinopathy in India – JAMA Ophthalmology (free)

Related: Google Launches Program in India to Screen Diabetics for Eye Conditions (studies and commentaries on the subject)

 

7 – Second International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions) – Breast Cancer Research and Treatment (free)

 

8 – Newer-Generation Antidepressants and Suicide Risk in Randomized Controlled Trials: A Re-Analysis of the FDA Database – Psychotherapy and Psychosomatics (free)

Commentary: New study: antidepressants significantly raise the risk of suicide in the treatment of depression for adults (free)

 

9 – Impact of sugar‐sweetened beverage taxes on purchases and dietary intake: Systematic review and meta‐analysis – Obesity Reviews (free)

Related: Cochrane Review: Environmental Interventions to Reduce the Consumption of Sugar‐sweetened Beverages and Their Effects on Health (free study and commentaries) AND Soda Tax Linked to a 50 Percent Reduction in Sugary Drink Consumption (link to abstract and several resources on the subject) AND AAP/AHA Policy Statement: Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents (free statement and commentaries) AND Taxes on Sugar-Sweetened Beverages Associated with Reduced Consumption (link to abstract and commentaries)

 

10 – Statin users have an elevated risk of dysglycemia and new‐onset‐diabetes – Diabetes Metabolism Research and Reviews (free PDF)

Commentaries: Statins may double the risk of type 2 diabetes – Medical News Today (free) AND Cholesterol Medication Could Invite Diabetes, Study Suggests – Ohio State University (free)

Related Studies: Another Observational Study Showing Association of Statin Use with Risk of New‐Onset Diabetes Mellitus (free study and commentaries) AND Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes (free study and commentaries)

 


Study: Types of Sedentary Behavior and Risk of Cardiovascular Events and Mortality in Blacks

28 Jun, 2019 | 07:33h | UTC

Types of Sedentary Behavior and Risk of Cardiovascular Events and Mortality in Blacks: The Jackson Heart Study – Journal of the American Heart Association (free)

Commentary: Sitting in front of TV may be worse for health than desk job – Reuters (free) AND Heart risk raised by sitting in front of the TV, not by sitting at work, finds study – Columbia University Irving Medical Center (free)

 


New Guidelines Aim to Expand Palliative Care Beyond Specialists

27 Jun, 2019 | 10:37h | UTC

New Guidelines Aim to Expand Palliative Care Beyond Specialists – JAMA (free for a limited period)

Audio Summary: New Guidelines Aim to Expand Palliative Care Beyond Specialists (free)

Original Guideline: Clinical Practice Guidelines for Quality Palliative Care (free article and commentaries)

Related: Building a Better Death, One Conversation at a Time – JAMA (free for a limited period)

 


Guideline: Diagnosing and Managing Work‐related Mental Health Conditions in General Practice

27 Jun, 2019 | 10:41h | UTC

Diagnosing and managing work‐related mental health conditions in general practice: new Australian clinical practice guidelines – The Medical Journal of Australia (free)

 


[Abstract Only] Meta-Analysis: Population-level Impact of HPV Vaccination Programs

27 Jun, 2019 | 10:35h | UTC

Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentaries: Vaccination programs substantially reduce HPV infections and precancerous cervical lesions – Laval University (free) AND Hopes raised of cervical cancer eradication – BBC (free) AND Study shows major real-world impact of cervical cancer vaccines – Reuters (free)

 

Related Commentary on Twitter

 


Randomized Trial: Amisulpride for the Rescue Treatment of Postoperative Nausea or Vomiting

27 Jun, 2019 | 09:25h | UTC

Amisulpride for the Rescue Treatment of Postoperative Nausea or Vomiting in Patients Failing Prophylaxis: A Randomized, Placebo-controlled Phase III Trial – Anesthesiology (free)

Related Study: Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Amisulpride as Treatment of Established Postoperative Nausea and Vomiting in Patients Who Have Had No Prior Prophylaxis (link to abstract)

 


Study: Same‐Day Discharge After Elective Percutaneous Coronary Interventions Seems Safe

27 Jun, 2019 | 10:39h | UTC

Same‐Day Discharge After Elective Percutaneous Coronary Interventions in Ontario, Canada – Journal of the American Heart Association (free)

Editorial: Same‐Day Discharge After Elective Uncomplicated Percutaneous Coronary Interventions (free)

Commentaries: Same-Day Discharge Safe After Elective PCI, Canadian Study Affirms – TCTMD (free) AND New study suggests same-day discharge after non-surgical heart procedure could save money and free up hospital beds – ICES (free)

Related Study: Same-Day Discharge After Elective PCI Seems Safe and Reduce Costs (free)

 


International Consensus on Lesions of Uncertain Malignant Potential in the Breast (B3 lesions)

27 Jun, 2019 | 09:17h | UTC

Second International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions) – Breast Cancer Research and Treatment (free)

 


Study: Performance of a Deep-Learning Algorithm vs Manual Grading for Detecting Diabetic Retinopathy

27 Jun, 2019 | 09:19h | UTC

Performance of a Deep-Learning Algorithm vs Manual Grading for Detecting Diabetic Retinopathy in India – JAMA Ophthalmology (free)

Related: Google Launches Program in India to Screen Diabetics for Eye Conditions (studies and commentaries on the subject)

 


Study: Antidepressants May Increase Suicide Risk

27 Jun, 2019 | 09:14h | UTC

Newer-Generation Antidepressants and Suicide Risk in Randomized Controlled Trials: A Re-Analysis of the FDA Database – Psychotherapy and Psychosomatics (free)

Commentary: New study: antidepressants significantly raise the risk of suicide in the treatment of depression for adults (free)

 


Observational Study Points to an Increased Risk of Diabetes Among Patients Using Statins

27 Jun, 2019 | 08:54h | UTC

Statin users have an elevated risk of dysglycemia and new‐onset‐diabetes – Diabetes Metabolism Research and Reviews (free PDF)

Commentaries: Statins may double the risk of type 2 diabetes – Medical News Today (free) AND Cholesterol Medication Could Invite Diabetes, Study Suggests – Ohio State University (free)

Related Studies: Another Observational Study Showing Association of Statin Use with Risk of New‐Onset Diabetes Mellitus (free study and commentaries) AND Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes (link to abstract and commentaries)

 


Meta-Analysis: Impact of Sugar‐sweetened Beverage Taxes on Purchases and Dietary Intake

27 Jun, 2019 | 09:05h | UTC

Impact of sugar‐sweetened beverage taxes on purchases and dietary intake: Systematic review and meta‐analysis – Obesity Reviews (free)

Related: Cochrane Review: Environmental Interventions to Reduce the Consumption of Sugar‐sweetened Beverages and Their Effects on Health (free study and commentaries) AND Soda Tax Linked to a 50 Percent Reduction in Sugary Drink Consumption (link to abstract and several resources on the subject) AND AAP/AHA Policy Statement: Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents (free statement and commentaries) AND Taxes on Sugar-Sweetened Beverages Associated with Reduced Consumption (link to abstract and commentaries)

 


Wed June 26 – 10 Stories of The Day!

26 Jun, 2019 | 08:00h | UTC

 

1 – Hypertension in pregnancy: diagnosis and management – National Institute for Health and Care Excellence (free)

Related Guidelines: WHO recommendations: Drug treatment for severe hypertension in pregnancy – World Health Organization (free) AND Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy (free)

Related Reviews: State-of-the-Art Diagnosis and Treatment of Hypertension in Pregnancy – Mayo Clinic Proceedings (free) AND Hypertension in pregnancy: Pathophysiology and treatment – SAGE Open Medicine (free)

 

2 – Depression in children and young people: identification and management – National Institute for Health and Care Excellence (free)

Related: AAP Guidelines for Adolescent Depression in Primary Care (free)

 

3 – Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality – JAMA (free for a limited period)

Editorial: Accuracy of Airflow Obstruction Thresholds for Predicting COPD-Related Hospitalization and Mortality: Can Simple Diagnostic Thresholds Be Used for a Complex Disease? (free)

Commentary: Study funded by NIH supports optimal threshold for diagnosing COPD – NIH News Releases (free)

“These results support the use of FEV1:FVC less than 0.70 to identify individuals at risk of clinically significant COPD.”

 

4 – Effect of 1-Month Dual Antiplatelet Therapy Followed by Clopidogrel vs 12-Month Dual Antiplatelet Therapy on Cardiovascular and Bleeding Events in Patients Receiving PCI: The STOPDAPT-2 Randomized Clinical Trial – JAMA (free for a limited period)

Related Study: Effect of P2Y12 Inhibitor Monotherapy vs Dual Antiplatelet Therapy on Cardiovascular Events in Patients Undergoing Percutaneous Coronary Intervention: The SMART-CHOICE Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Dual Antiplatelet Therapy: Is It Time to Cut the Cord With Aspirin? (free for a limited period)

Audio Summary: Reducing the Intensity of Antithrombotic Therapy Following Coronary Stent Procedures (free)

Commentaries: Shorter Dual Antiplatelet Therapy May Be an Option for Patients Undergoing PCI – NEJM Journal Watch (free) AND Short and Optimal Duration of Dual Antiplatelet Therapy After Everolimus-Eluting Cobalt-Chromium Stent-2 – STOPDAPT-2 – American College of Cardiology (free)

 

5 – Did This Patient Have Cardiac Syncope? The Rational Clinical Examination Systematic Review – JAMA (free for a limited period)

Related Guidelines: 2018 ESC Guidelines for the diagnosis and management of syncope – European Heart Journal (free) AND 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (free)

 

6 – Choosing Wisely: Case Studies from the Top 10 Recommendations Across Campaigns – The Commonwealth Fund (free case studies)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

7 – Incidence of New Onset Diabetes Mellitus Secondary to Acute Pancreatitis: A Systematic Review and Meta-Analysis – Frontiers in Physiology (free)

 

8 – Alex Nowbar’s journal reviews, 25 June 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 

9 – Risk of ESKD in Older Live Kidney Donors with Hypertension – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)

Commentary: Higher Risk of Kidney Failure in Older Donors With Hypertension – Medscape (free registration required)

 

10 – Cognitive Decline Before and After Incident Coronary Events – Journal of the American College of Cardiology (free)

Commentaries: Cognitive decline may accelerate after heart attack, angina – American College of Cardiology (free) AND Ischemic Events Worsen Long-term Cognitive Decline – TCTMD (free) AND Heart problems may hasten cognitive decline – Reuters (free)

 


NICE Guideline: Depression in Children and Young People

26 Jun, 2019 | 07:46h | UTC

Depression in children and young people: identification and management – National Institute for Health and Care Excellence (free)

Related: AAP Guidelines for Adolescent Depression in Primary Care (free)

 


NICE Guideline: Hypertension in Pregnancy

26 Jun, 2019 | 07:54h | UTC

Hypertension in pregnancy: diagnosis and management – National Institute for Health and Care Excellence (free)

Related Guidelines: WHO recommendations: Drug treatment for severe hypertension in pregnancy – World Health Organization (free) AND Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy (free)

Related Reviews: State-of-the-Art Diagnosis and Treatment of Hypertension in Pregnancy – Mayo Clinic Proceedings (free) AND Hypertension in pregnancy: Pathophysiology and treatment – SAGE Open Medicine (free)

 


Did This Patient Have Cardiac Syncope? The Rational Clinical Examination Systematic Review

26 Jun, 2019 | 01:48h | UTC

Did This Patient Have Cardiac Syncope? The Rational Clinical Examination Systematic Review – JAMA (free for a limited period)

Related Guidelines: 2018 ESC Guidelines for the diagnosis and management of syncope – European Heart Journal (free) AND 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (free)

 


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