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Cohort Study: Flu Vaccine in Pregnancy Safe for Children and Mothers

12 Jul, 2019 | 07:44h | UTC

Health outcomes of young children born to mothers who received 2009 pandemic H1N1 influenza vaccination during pregnancy: retrospective cohort study – The BMJ (free)

Commentaries: No link between flu vaccine in pregnancy and later health problems in children – The BMJ (free) AND Swine flu jab in pregnancy safe for children as well as mothers – OnMedica (free)

 


Perspective – New Drugs: Where Did We Go Wrong and What Can We do Better?

12 Jul, 2019 | 07:13h | UTC

New drugs: where did we go wrong and what can we do better? – The BMJ (free)

Commentary: No evidence of added benefit for most new drugs entering German healthcare system – The BMJ (free)

 

Related Commentary on Twitter

https://twitter.com/bmj_latest/status/1149181569321623552

 


[Abstract Only] Meta-analysis: Association Between Blood Pressure Variability, Cardiovascular Disease and Mortality In Type 2 Diabetes

12 Jul, 2019 | 07:45h | UTC

Association Between Blood Pressure Variability, Cardiovascular Disease And Mortality In Type 2 Diabetes: A Systematic Review And Meta‐Analysis – Diabetes, Obesity and Metabolism (link to abstract – $ for full-text)

Commentary: Systolic BP variability associated with increased risk of death, CV events in patients with type 2 diabetes, meta-analysis finds – ACP Diabetes (free)

 


Cohort Study: Quantity and Quality of Mental Activities and the Risk of Mild Cognitive Impairment

12 Jul, 2019 | 06:18h | UTC

Quantity and quality of mental activities and the risk of incident mild cognitive impairment – Neurology (free PDF)

Commentary: Mentally stimulating activities linked to lower risk or delay of age-related memory loss – News Medical (free)

 

Related Commentary on Twitter

 


Cohort Study: Possible Link Between Sugary Drinks and Cancer

12 Jul, 2019 | 06:32h | UTC

Sugary drink consumption and risk of cancer: results from NutriNet-Santé prospective cohort – The BMJ (free)

Commentaries: Possible link between sugary drinks and cancer – The BMJ (free) Sugary drinks linked to cancer – NHS Choices (free) AND A small glass of juice or soda a day is linked to increased risk of cancer, study finds – CNN (free) AND Are sugary drinks causing cancer? – BBC (free)

 


Thu July 11 – 10 Stories of The Day!

11 Jul, 2019 | 11:20h | UTC

 

1 – C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: CRP Testing Can Safely Reduce Antibiotic Use for COPD Exacerbations – NEJM Journal Watch (free) AND Fingerprick Biomarker Test Can Reduce Use of Antibiotics in COPD Flares – MedicalResearch.com (free)

 

2 – Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries – Journal of the American Heart Association (free)

Editorial: Myocardial Infarction With Nonobstructive Coronary Arteries: A Call for Individualized Treatment (free)

Related: Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association (free) AND The What, When, Who, Why, How and Where of Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA) – Circulation Journal (free) AND Systematic Review of Patients Presenting With Suspected Myocardial Infarction and Nonobstructive Coronary Arteries – Circulation (free) AND Nonobstructive Versus Obstructive Coronary Artery Disease in Acute Coronary Syndrome: A Meta‐Analysis – Journal of the American Heart Association (free)

“Patients with MINOCA and those with myocardial infarction with obstructive coronary artery disease had comparable clinical outcomes. Use of renin‐angiotensin system blockers and statins was associated with lower mortality in patients with MINOCA.”

 

3 – Microvascular Disease, Peripheral Artery Disease and Amputation – Circulation (free PDF)

Commentaries: Microvascular Disease Quadruples Risk of Leg Amputation – TCTMD (free) AND Microvascular Disease Anywhere in the Body May Be Linked to Higher Risk of Leg Amputations – American Heart Association (free)

 

4 – Drug-induced endocrinopathies and diabetes: a combo-endocrinology overview – European Journal of Endocrinology (free)

 

5 – Pathophysiology and management of diabetic gastroenteropathy – Therapeutics Advances in Gastroenterology (free)

 

6 – Quality Improvement Goals for Acute Kidney Injury – Clinical Journal of the American Society of Nephrology (free)

“Quality Improvement Goals for Acute Kidney Injury: “The AKI care process starts with the community, continues in the hospital, and ends in community, and each of these phases requires specific intervention.”” (via @CCCNPitt see Tweet)

 

7 – Ann Robinson’s journal review, 10 July 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 

8 – Effect of Aerobic and Resistance Exercise on Cardiac Adipose Tissues: Secondary Analyses From a Randomized Clinical Trial – JAMA Cardiology (free link for a limited period)

Commentaries: Weight Training, Aerobic Exercise Affect Cardiac Fat Mass in Different Ways – TCTMD (free) AND Aerobic, resistance exercise may reduce coronary risk for people with belly fat – UPI (free)

 

9 – Systolic Blood Pressure and Risk of Valvular Heart Disease: A Mendelian Randomization Study – JAMA Cardiology (free link for a limited period)

“Lifetime exposure to elevated systolic BP appears to be associated with an increased risk of major valvular heart disease.”

 

10 – Press Release: HPV vaccine could prevent over 100,000 cancers – Public Health England (free)

Commentaries: HPV vaccine for boys ‘will prevent thousands of cancers’ – BBC (free) AND Expert reaction to HPV vaccine, modelling of cancer prevention, and introduction in September of vaccine programme for boys – Science Media Centre (free) AND UK offers HPV vaccines to boys, aims to stop 100,000 cancer cases – Reuters (free)

 


Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries

11 Jul, 2019 | 11:08h | UTC

Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries – Journal of the American Heart Association (free)

Editorial: Myocardial Infarction With Nonobstructive Coronary Arteries: A Call for Individualized Treatment (free)

Related: Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association (free) AND The What, When, Who, Why, How and Where of Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA) – Circulation Journal (free) AND Systematic Review of Patients Presenting With Suspected Myocardial Infarction and Nonobstructive Coronary Arteries – Circulation (free) AND Nonobstructive Versus Obstructive Coronary Artery Disease in Acute Coronary Syndrome: A Meta‐Analysis – Journal of the American Heart Association (free)

“Patients with MINOCA and those with myocardial infarction with obstructive coronary artery disease had comparable clinical outcomes. Use of renin‐angiotensin system blockers and statins was associated with lower mortality in patients with MINOCA.”

 


[Abstract Only] Randomized Trial: C-Reactive Protein Can Guide Antibiotics for COPD Exacerbations

11 Jul, 2019 | 11:18h | UTC

C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: CRP Testing Can Safely Reduce Antibiotic Use for COPD Exacerbations – NEJM Journal Watch (free) AND Fingerprick Biomarker Test Can Reduce Use of Antibiotics in COPD Flares – MedicalResearch.com (free)

 


Drug-induced Endocrinopathies and Diabetes

11 Jul, 2019 | 10:27h | UTC

Drug-induced endocrinopathies and diabetes: a combo-endocrinology overview – European Journal of Endocrinology (free)

 


Cohort Study: Microvascular Disease, Peripheral Artery Disease and Amputation

11 Jul, 2019 | 10:33h | UTC

Microvascular Disease, Peripheral Artery Disease and Amputation – Circulation (free PDF)

Commentaries: Microvascular Disease Quadruples Risk of Leg Amputation – TCTMD (free) AND Microvascular Disease Anywhere in the Body May Be Linked to Higher Risk of Leg Amputations – American Heart Association (free)

 


Quality Improvement Goals for Acute Kidney Injury

11 Jul, 2019 | 10:15h | UTC

Quality Improvement Goals for Acute Kidney Injury – Clinical Journal of the American Society of Nephrology (free)

 

Related Commentary on Twitter

 


Randomized Trial: Effect of Aerobic vs. Resistance Exercise on Cardiac Adipose Tissues

11 Jul, 2019 | 09:55h | UTC

Effect of Aerobic and Resistance Exercise on Cardiac Adipose Tissues: Secondary Analyses From a Randomized Clinical Trial – JAMA Cardiology (free link for a limited period)

Commentaries: Weight Training, Aerobic Exercise Affect Cardiac Fat Mass in Different Ways – TCTMD (free) AND Aerobic, resistance exercise may reduce coronary risk for people with belly fat – UPI (free)

 


Pathophysiology and Management of Diabetic Gastroenteropathy

11 Jul, 2019 | 10:21h | UTC

Pathophysiology and management of diabetic gastroenteropathy – Therapeutics Advances in Gastroenterology (free)

 


Ann Robinson’s journal review—10 July 2019

11 Jul, 2019 | 09:59h | UTC

Ann Robinson’s journal review, 10 July 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Study: Systolic Blood Pressure and Risk of Valvular Heart Disease

11 Jul, 2019 | 09:49h | UTC

Systolic Blood Pressure and Risk of Valvular Heart Disease: A Mendelian Randomization Study – JAMA Cardiology (free link for a limited period)

“Lifetime exposure to elevated systolic BP appears to be associated with an increased risk of major valvular heart disease.”

 

Related Commentary on Twitter

 


Wed July 10 – 10 Stories of The Day!

10 Jul, 2019 | 10:28h | UTC

 

1 – News Release: WHO updates global guidance on medicines and diagnostic tests to address health challenges, prioritize highly effective therapeutics, and improve affordable access – World Health Organization (free)

Guidance: World Health Organization model list of essential medicines: 21st list 2019 (free PDF) AND Executive summary: the selection and use of essential medicines 2019 (free PDF) AND World Health Organization model list of essential medicines for children: 7th list 2019 (free PDF) AND Second WHO Model List of Essential In Vitro Diagnostics (free PDF)

Commentaries: WHO List of Essential Tests Gets An Upgrade – Forbes (free) AND WHO adds new antibiotics to essential medicines list – CIDRAP (free)

 

2 – Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury – Acta Neurochirurgica (free)

 

3 – Management of Infants at Risk for Group B Streptococcal Disease – Pediatrics (free)

News Releases: AAP Updates Guidance on Preventing, Managing Infants with Group B Strep Disease – American Academy of Pediatrics (free) AND Early-onset group B strep: New guidance includes changes in dosing, assessment – AAP News (free)

Related: ACOG Guideline: Prevention of Early-Onset Group B Streptococcal Disease in Newborns (free)

 

4 – Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children – Nature Medicine (link to abstract – $ for full-text)

News Release: A third of children up to age 3 exposed to Zika in-utero have neurological problems – UCLA (free) AND Maternal Zika infection tied to poor development in 32% of tots – CIDRAP (free)

 

5 – Selective Referral Using CCTA Versus Direct Referral for Individuals Referred to Invasive Coronary Angiography for Suspected CAD: A Randomized, Controlled, Open-Label Trial – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)

Commentary: Coronary Computed Tomographic Angiography for Selective Cardiac Catheterization – CONSERVE – American College of Cardiology (free)

 

6 – Association Between Androgen Deprivation Therapy Use and Diagnosis of Dementia in Men with Prostate Cancer – JAMA Network Open (free)

Commentaries: Hormone therapy for prostate cancer may raise risk of Alzheimer’s, Dementia – Penn Medicine (free) AND Prostate cancer treatment linked to heightened Alzheimer’s risk – UPI (free) AND Men’s dementia risk higher after androgen deprivation therapy – OnMedica (free) AND Risk of dementia rises with prostate cancer hormone-blocking therapy – Reuters (free)

 

7 – Subclinical Hypothyroidism – A Review – JAMA (free link for a limited period)

Related: BMJ Guideline: Treatment of Subclinical Hypothyroidism (free guideline and commentaries)

 

8 – Evaluating and Managing Bradycardia – Trends in Cardiovascular Medicine (free)

Related: 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay (free guideline and resources)

 

9 – Management of acute variceal hemorrhage – F1000Research (free)

 

10 – Neuropsychiatric Sequelae in Adolescents With Acute Synthetic Cannabinoid Toxicity – Pediatrics (link to abstract – $ for full-text)

News Release: Study: Seizures, coma more common with synthetic cannabinoids than cannabis – American Academy of Pediatrics (free)

Commentary: Synthetic Cannabinoids Associated with More Comas and Seizures in Teens – NEJM Journal Watch (free)

 


HPV Vaccine Could Prevent over 100,000 Cancers in the UK

11 Jul, 2019 | 09:41h | UTC

Press Release: HPV vaccine could prevent over 100,000 cancers – Public Health England (free)

Commentaries: HPV vaccine for boys ‘will prevent thousands of cancers’ – BBC (free) AND Expert reaction to HPV vaccine, modelling of cancer prevention, and introduction in September of vaccine programme for boys – Science Media Centre (free) AND UK offers HPV vaccines to boys, aims to stop 100,000 cancer cases – Reuters (free)

 


WHO Updates Global Guidance on Medicines and Diagnostic Tests

10 Jul, 2019 | 10:25h | UTC

News Release: WHO updates global guidance on medicines and diagnostic tests to address health challenges, prioritize highly effective therapeutics, and improve affordable access – World Health Organization (free)

Guidance: World Health Organization model list of essential medicines: 21st list 2019 (free PDF) AND Executive summary: the selection and use of essential medicines 2019 (free PDF) AND World Health Organization model list of essential medicines for children: 7th list 2019 (free PDF) AND Second WHO Model List of Essential In Vitro Diagnostics (free PDF)

Commentaries: WHO List of Essential Tests Gets An Upgrade – Forbes (free) AND WHO adds new antibiotics to essential medicines list – CIDRAP (free)

 


Consensus statement on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury

10 Jul, 2019 | 10:09h | UTC

Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury – Acta Neurochirurgica (free)

 


[Abstract Only] Study: Nearly A Third of Children Exposed to Zika In-utero Develop Neurological Problems by Age 3

10 Jul, 2019 | 09:53h | UTC

Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children – Nature Medicine (link to abstract – $ for full-text)

News Release: A third of children up to age 3 exposed to Zika in-utero have neurological problems – UCLA (free) AND Maternal Zika infection tied to poor development in 32% of tots – CIDRAP (free)

 

Related Commentary on Twitter

 


AAP Clinical Report: Management of Infants at Risk for Group B Streptococcal Disease

10 Jul, 2019 | 10:06h | UTC

Management of Infants at Risk for Group B Streptococcal Disease – Pediatrics (free)

News Releases: AAP Updates Guidance on Preventing, Managing Infants with Group B Strep Disease – American Academy of Pediatrics (free) AND Early-onset group B strep: New guidance includes changes in dosing, assessment – AAP News (free)

Related: ACOG Guideline: Prevention of Early-Onset Group B Streptococcal Disease in Newborns (free)

 


[Abstract Only] Randomized Trial: Selective Referral Using CCTA First vs. Direct Referral for Individuals with Indication of Invasive Coronary Angiography for Suspected CAD

10 Jul, 2019 | 09:50h | UTC

Selective Referral Using CCTA Versus Direct Referral for Individuals Referred to Invasive Coronary Angiography for Suspected CAD: A Randomized, Controlled, Open-Label Trial – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)

Commentary: Coronary Computed Tomographic Angiography for Selective Cardiac Catheterization – CONSERVE – American College of Cardiology (free)

 


Review: Subclinical Hypothyroidism

10 Jul, 2019 | 02:36h | UTC

Subclinical Hypothyroidism – A Review – JAMA (free link for a limited period)

Related: BMJ Guideline: Treatment of Subclinical Hypothyroidism (free guideline and commentaries)

 


Androgen Deprivation Therapy Linked to Increased Risk of Dementia in Men with Prostate Cancer

10 Jul, 2019 | 09:30h | UTC

Association Between Androgen Deprivation Therapy Use and Diagnosis of Dementia in Men with Prostate Cancer – JAMA Network Open (free)

Commentaries: Hormone therapy for prostate cancer may raise risk of Alzheimer’s, Dementia – Penn Medicine (free) AND Prostate cancer treatment linked to heightened Alzheimer’s risk – UPI (free) AND Men’s dementia risk higher after androgen deprivation therapy – OnMedica (free) AND Risk of dementia rises with prostate cancer hormone-blocking therapy – Reuters (free)

 


Review: Management of Acute Variceal Hemorrhage

10 Jul, 2019 | 02:31h | UTC

Management of acute variceal hemorrhage – F1000Research (free)

 


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