Archives
Guideline: Diagnosis and Management of Metabolic Acidosis
16 Aug, 2019 | 08:15h | UTC
Report: How Doctors in Senior Leadership Roles Establish and Maintain a Positive Patient-centered Culture
16 Aug, 2019 | 08:10h | UTCSummary: How doctors in senior leadership roles establish and maintain a positive patient-centred culture (free)
Commentary: Do You Work in a ‘Diva Subculture’? – Medscape (free registration required)
Related: Healing the Professional Culture of Medicine – Mayo Clinic Proceedings (free) AND Understanding organisational culture for healthcare quality improvement – The BMJ (free)
Systematic Review: Resident Physicians are at Increased Risk for Dangerous Driving After Extended-duration Work Shifts
16 Aug, 2019 | 08:02h | UTCSource: Hospital Medicine Virtual Journal Club
Communication Strategies for Sharing Prognostic Information with Patients: Beyond Survival Statistics
16 Aug, 2019 | 08:05h | UTCCommunication Strategies for Sharing Prognostic Information With Patients: Beyond Survival Statistics – JAMA (free for a limited period)
See also: Author Interview (free audio)
Meta-Analysis: Association Between Vitamin D Supplementation and Mortality
16 Aug, 2019 | 07:59h | UTCRelated: Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention (link to abstract and commentary) AND NICE Guideline: Vitamin D Supplementation (free)
Vitamin D supplementation was not associated with all-cause mortality, cardiovascular mortality, or non-cancer, non-cardiovascular mortality. However, Vitamin D supplementation statistically significantly reduced the risk of cancer death by 16%.
Related Commentary on Twitter
Vitamin D supplementation alone was not associated with all cause mortality in adults compared with placebo or no treatment. However, it was associated with a reduced risk of cancer mortality by 16%, finds #BMJResearch https://t.co/jc4Tdxl6Bb
— The BMJ (@bmj_latest) August 12, 2019
Essential Tremor: Diagnosis and Management
16 Aug, 2019 | 07:55h | UTCEssential tremor: diagnosis and management – The BMJ (free for a limited period)
CDC Updates Recommendations for Human Papillomavirus Vaccination for Adults
16 Aug, 2019 | 07:53h | UTCCommentaries: CDC Recommends HPV Catch-Up Vaccine in Those 26 and Younger – NEJM Journal Watch (free) AND Confused About Who Should Get the HPV Vaccine, and When? The CDC Has New Recommendations – Time (free)
Thu August 15 – 10 Stories of The Day!
15 Aug, 2019 | 10:30h | UTC
See also: Practice guideline update summary: Acute treatment of migraine in children and adolescents – Neurology (free PDF)
Commentaries: AAN issues guidelines for treatment of migraine in children and teens – American Academy of Neurology (free) AND Guidelines Updated on Preventing and Treating Migraine in Children and Teens – NEJM Journal Watch (free)
Related Position Statements on Perioperative Opioid Therapy: American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Management of Patients on Preoperative Opioid Therapy (free) AND American Society for Enhanced Recovery and Perioperative Quality Initiative-4 Joint Consensus Statement on Persistent Postoperative Opioid Use: Definition, Incidence, Risk Factors, and Health Care System Initiatives (free)
See also: American Society of Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statements (free) AND Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)
3 – Optimal Combination of Compression Rate and Depth During Cardiopulmonary Resuscitation for Functionally Favorable Survival – JAMA Cardiology (free for a limited period)
Commentaries: Push Hard, Push Fast, Do Not Stop—Optimal Chest Compression Rate and Depth – JAMA Cardiology (free for a limited period) AND Study Details Optimal CPR Speed, Depth – NEJM Journal Watch (free)
Related: Performing CPR? Humming the Macarena Could Help (free)
4 – Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk – JAMA (free for a limited period)
Editorial: Gluten and Celiac Disease Risk: Is It Just a Matter of Quantity? (free for a limited period)
Commentaries: Association between coeliac disease risk and gluten intake confirmed – Lund University (free) High Gluten Diet Adds to Risk of Celiac Disease In Genetically Predisposed Children – MedicalResearch.com (free) AND Eating more gluten early in life is tied to children’s higher risk of celiac disease, a study says – CNN (free)
5 – Imaging of Pulmonary Hypertension: Pictorial Essay – Chest (free)
Related Guidelines: Therapy for Pulmonary Arterial Hypertension in Adults 2018: Update of the CHEST Guideline and Expert Panel Report (free) AND 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free) AND Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society (free) AND 2018 TSOC guideline focused update on diagnosis and treatment of pulmonary arterial hypertension – Journal of the Formosan Medical Association (free)
6 – Key concepts for making informed choices – Nature (free)
7 – An augmented reality microscope with real-time artificial intelligence integration for cancer diagnosis – Nature Medicine (free for a limited period)
8 – Perspective: Healthcare Needs AI, AI Needs Causality – Forbes (free)
10 – Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary: Don’t Use More Than 400 mg of Ibuprofen for Pain Control – NEJM Journal Watch (free for a limited period)
[Abstract Only] Study: Diabetes Being Overtreated in Many Vulnerable Clinically Complex Adults
16 Aug, 2019 | 07:50h | UTCSevere Hypoglycemia Attributable to Intensive Glucose-Lowering Therapy Among US Adults With Diabetes – Mayo Clinic Proceedings (link to abstract – $ for full-text)
Commentary: Too Much of a Good Thing Can Be Dangerous, Finds Researchers Investigating Hypoglycemia – Mayo Clinic (free)
Related Studies: Overtreatment and Deintensification of Diabetic Therapy among Medicare Beneficiaries – Journal of General Internal Medicine (free) AND Rates of Deintensification of Blood Pressure and Glycemic Medication Treatment Based on Levels of Control and Life Expectancy in Older Patients With Diabetes Mellitus – JAMA Internal Medicine (free)
Study: Optimal Combination of Compression Rate and Depth During CPR for Functionally Favorable Survival
15 Aug, 2019 | 08:22h | UTCOptimal Combination of Compression Rate and Depth During Cardiopulmonary Resuscitation for Functionally Favorable Survival – JAMA Cardiology (free for a limited period)
Commentaries: Push Hard, Push Fast, Do Not Stop—Optimal Chest Compression Rate and Depth – JAMA Cardiology (free for a limited period) AND Study Details Optimal CPR Speed, Depth – NEJM Journal Watch (free)
Related: Performing CPR? Humming the Macarena Could Help (free)
Consensus Statement for Enhanced Recovery: Perioperative Opioid Minimization in Opioid-Naïve Patients
15 Aug, 2019 | 08:37h | UTCRelated Position Statements on Perioperative Opioid Therapy: American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Management of Patients on Preoperative Opioid Therapy (free) AND American Society for Enhanced Recovery and Perioperative Quality Initiative-4 Joint Consensus Statement on Persistent Postoperative Opioid Use: Definition, Incidence, Risk Factors, and Health Care System Initiatives (free)
See also: American Society of Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statements (free) AND Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)
AAN Guidelines for the Pharmacologic Prevention and Treatment of Migraine in Children and Adolescents
15 Aug, 2019 | 10:27h | UTCSee also: Practice guideline update summary: Acute treatment of migraine in children and adolescents – Neurology (free PDF)
Commentaries: AAN issues guidelines for treatment of migraine in children and teens – American Academy of Neurology (free) AND Guidelines Updated on Preventing and Treating Migraine in Children and Teens – NEJM Journal Watch (free)
Review: Imaging of Pulmonary Hypertension
15 Aug, 2019 | 07:58h | UTCImaging of Pulmonary Hypertension: Pictorial Essay – Chest (free for a limited period)
Related Guidelines: Therapy for Pulmonary Arterial Hypertension in Adults 2018: Update of the CHEST Guideline and Expert Panel Report (free) AND 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free) AND Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society (free) AND 2018 TSOC guideline focused update on diagnosis and treatment of pulmonary arterial hypertension – Journal of the Formosan Medical Association (free)
AI-Powered Microscope Can Detect Tumor Cells in Histology Slides
15 Aug, 2019 | 07:41h | UTCAn augmented reality microscope with real-time artificial intelligence integration for cancer diagnosis – Nature Medicine (free for a limited period)
Related Commentary on Twitter
Researchers at @GoogleAI have designed an #ArtificialIntelligence -powered microscope able to detect tumor cells in histology slides that could accelerate #pathology workflows for #cancer diagnosis―Read full paper 👉 https://t.co/mTa9z5rUdK #digitalmedicine #Biotechnology #AI pic.twitter.com/CPhEPRCRwE
— Nature Medicine (@NatureMedicine) August 12, 2019
Study: High Gluten Intake During Childhood May Increase the Risk of Celiac Disease in Genetically Predisposed Children
15 Aug, 2019 | 08:12h | UTCAssociation of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk – JAMA (free for a limited period)
Editorial: Gluten and Celiac Disease Risk: Is It Just a Matter of Quantity? (free for a limited period)
Commentaries: Association between coeliac disease risk and gluten intake confirmed – Lund University (free) High Gluten Diet Adds to Risk of Celiac Disease In Genetically Predisposed Children – MedicalResearch.com (free) AND Eating more gluten early in life is tied to children’s higher risk of celiac disease, a study says – CNN (free)
Key Concepts for Making Informed Choices
15 Aug, 2019 | 07:47h | UTCKey concepts for making informed choices – Nature (free)
Perspective: Healthcare Needs AI, AI Needs Causality
15 Aug, 2019 | 07:09h | UTCHealthcare Needs AI, AI Needs Causality – Forbes (free)
[Abstract Only] Randomized Trial: Ibuprofen Administered at Doses of 400, 600, and 800 mg Had Similar Analgesic Efficacy in Acute Pain.
15 Aug, 2019 | 06:58h | UTCComparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary: Don’t Use More Than 400 mg of Ibuprofen for Pain Control – NEJM Journal Watch (free for a limited period)
Related Commentary on Twitter
Hot off the Press: Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial https://t.co/Wq6PCgRaUw @painfreeED pic.twitter.com/7PLtD3IJ7I
— AnnalsofEM (@AnnalsofEM) August 13, 2019
Guidelines for the Management of Common Congenital Heart Diseases
15 Aug, 2019 | 07:02h | UTC
Wed August 14 – 10 Stories of The Day!
14 Aug, 2019 | 10:46h | UTC
1 – Two Ebola drugs show promise amid ongoing outbreak – Nature (free)
See also: Ebola drugs show ‘90% survival rate’ in breakthrough trial – BBC (free) AND AND 2 Experimental Ebola Drugs Saved Lives In Congo Outbreak – NPR (free) AND A Cure for Ebola? Two New Treatments Prove Highly Effective in Congo – The New York Times (10 articles per month are free)
2 – Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia – JAMA (free for a limited period)
Related Research: Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions – JAMA (free for a limited period)
Editorial: Blood Pressure, Brain Volume and White Matter Hyperintensities, and Dementia Risk (free for a limited period)
Video Summary: Hypertension and Dementia (free)
Commentary: Expert reaction to two studies looking at blood pressure and dementia – Science Media Centre (free)
3 – Association Between Long-term Exposure to Ambient Air Pollution and Change in Quantitatively Assessed Emphysema and Lung Function – JAMA (free for a limited period)
Video Abstract: Ambient Air Pollution and Change in Emphysema and Lung Function (free)
Commentaries: Air Pollution May Be As Harmful To Your Lungs As Smoking Cigarettes, Study Finds – NPR (free) AND Study finds link between long-term exposure to air pollution and emphysema – NIH News Releases (free)
4 – Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text)
Related Study: Colonoscopy Adenoma Findings and Long-term Colorectal Cancer Incidence (free study, commentaries and guidelines on the subject)
Source: NEJM Journal Watch ($)
Related Guidelines: WHO Medical eligibility criteria for contraceptive use (free PDF) AND US Medical Eligibility Criteria for Contraceptive Use (free) AND UK Medical Eligibility Criteria for Contraceptive Use (free)
6 – Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review – JAMA (free for a limited period)
8 – The entire human brain in ‘unprecedented’ detail, thanks to powerful MRI – STAT (free)
Commentaries: For the first time, U.S. panel recommends screening adults for illicit drug use – STAT (free) AND Screen All Adult Patients for Drug Abuse, National Panel Urges – The New York Times (10 articles per month are free) AND
10 – Roles of cyberbullying, sleep, and physical activity in mediating the effects of social media use on mental health and wellbeing among young people in England: a secondary analysis of longitudinal data – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)
Commentaries: Social media use may harm teens’ mental health by disrupting positive activities, study says – CNN (free) AND Social-media use ‘disrupting teen sleep and exercise’ – BBC (free) AND Expert reaction to study on social media use and the role of cyberbullying, sleep and physical activity in the wellbeing in young people – Science Media Centre (free) AND Social Media’s Ill Effects in Teen Girls: 3 Factors Play Large Role – NEJM Journal Watch (free)
Experimental Ebola Drugs Show 90% Survival Rate
14 Aug, 2019 | 10:44h | UTCTwo Ebola drugs show promise amid ongoing outbreak – Nature (free)
See also: Ebola drugs show ‘90% survival rate’ in breakthrough trial – BBC (free) AND 2 Experimental Ebola Drugs Saved Lives In Congo Outbreak – NPR (free) AND A Cure for Ebola? Two New Treatments Prove Highly Effective in Congo – The New York Times (10 articles per month are free)
Study: Midlife to Late-Life Blood Pressure Patterns and Incident Dementia
14 Aug, 2019 | 10:33h | UTCAssociation of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia – JAMA (free for a limited period)
Related Research: Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions – JAMA (free for a limited period)
Editorial: Blood Pressure, Brain Volume and White Matter Hyperintensities, and Dementia Risk (free for a limited period)
Video Summary: Hypertension and Dementia (free)
Commentary: Expert reaction to two studies looking at blood pressure and dementia – Science Media Centre (free)
Study: Ambient Air Pollution and Change in Emphysema and Lung Function
14 Aug, 2019 | 08:41h | UTCAssociation Between Long-term Exposure to Ambient Air Pollution and Change in Quantitatively Assessed Emphysema and Lung Function – JAMA (free for a limited period)
Video Abstract: Ambient Air Pollution and Change in Emphysema and Lung Function (free)
Commentaries: Air Pollution May Be As Harmful To Your Lungs As Smoking Cigarettes, Study Finds – NPR (free) AND Study finds link between long-term exposure to air pollution and emphysema – NIH News Releases (free)
[Abstract Only] Cohort Study: Individuals with 1 or 2 Small Adenomas at Baseline Screening Colonoscopy Have a Similar Risk of Advanced Neoplasia over 10 years as Individuals with no Baseline Adenomas
14 Aug, 2019 | 08:34h | UTCBaseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text)
Related Study: Colonoscopy Adenoma Findings and Long-term Colorectal Cancer Incidence (free study, commentaries and guidelines on the subject)
Source: NEJM Journal Watch ($)
Review: Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications
14 Aug, 2019 | 08:29h | UTCExtracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review – JAMA (free for a limited period)


