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Guideline: Diagnosis and Management of Metabolic Acidosis

16 Aug, 2019 | 08:15h | UTC

Diagnosis and management of metabolic acidosis: guidelines from a French expert panel – Annals of Intensive Care (free)

 


Report: How Doctors in Senior Leadership Roles Establish and Maintain a Positive Patient-centered Culture

16 Aug, 2019 | 08:10h | UTC

How doctors in senior leadership roles establish and maintain a positive patient-centred culture – General Medical Council (free PDF)

Summary: How doctors in senior leadership roles establish and maintain a positive patient-centred culture (free)

Commentary: Do You Work in a ‘Diva Subculture’? – Medscape (free registration required)

Related: Healing the Professional Culture of Medicine – Mayo Clinic Proceedings (free) AND Understanding organisational culture for healthcare quality improvement – The BMJ (free)

 


Systematic Review: Resident Physicians are at Increased Risk for Dangerous Driving After Extended-duration Work Shifts

16 Aug, 2019 | 08:02h | UTC

Resident Physicians are at Increased Risk for Dangerous Driving after Extended-duration Work Shifts: A Systematic Review – Cureus (free)

Source: Hospital Medicine Virtual Journal Club

 


Communication Strategies for Sharing Prognostic Information with Patients: Beyond Survival Statistics

16 Aug, 2019 | 08:05h | UTC

Communication Strategies for Sharing Prognostic Information With Patients: Beyond Survival Statistics – JAMA (free for a limited period)

See also: Author Interview (free audio)

 


Meta-Analysis: Association Between Vitamin D Supplementation and Mortality

16 Aug, 2019 | 07:59h | UTC

Association between vitamin D supplementation and mortality: systematic review and meta-analysis – The BMJ (free)

Related: Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention (link to abstract and commentary) AND NICE Guideline: Vitamin D Supplementation (free)

Vitamin D supplementation was not associated with all-cause mortality, cardiovascular mortality, or non-cancer, non-cardiovascular mortality. However, Vitamin D supplementation statistically significantly reduced the risk of cancer death by 16%.

 

Related Commentary on Twitter

 


Essential Tremor: Diagnosis and Management

16 Aug, 2019 | 07:55h | UTC

Essential tremor: diagnosis and management – The BMJ (free for a limited period)

 


CDC Updates Recommendations for Human Papillomavirus Vaccination for Adults

16 Aug, 2019 | 07:53h | UTC

Human Papillomavirus Vaccination for Adults: Updated Recommendations of the Advisory Committee on Immunization Practices – Centers for Disease Control and Prevention (free)

Commentaries: CDC Recommends HPV Catch-Up Vaccine in Those 26 and Younger – NEJM Journal Watch (free) AND Confused About Who Should Get the HPV Vaccine, and When? The CDC Has New Recommendations – Time (free)

 


Thu August 15 – 10 Stories of The Day!

15 Aug, 2019 | 10:30h | UTC

 

1 – Practice guideline update summary: Pharmacologic treatment for pediatric migraine prevention – Neurology (fee PDF)

See also: Practice guideline update summary: Acute treatment of migraine in children and adolescents – Neurology (free PDF)

Commentaries: AAN issues guidelines for treatment of migraine in children and teens – American Academy of Neurology (free) AND Guidelines Updated on Preventing and Treating Migraine in Children and Teens – NEJM Journal Watch (free)

 

2 – American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Opioid Minimization in Opioid-Naïve Patients – Anesthesia & Analgesia (free)

Related Position Statements on Perioperative Opioid Therapy: American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Management of Patients on Preoperative Opioid Therapy (free) AND American Society for Enhanced Recovery and Perioperative Quality Initiative-4 Joint Consensus Statement on Persistent Postoperative Opioid Use: Definition, Incidence, Risk Factors, and Health Care System Initiatives (free)

See also: American Society of Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statements (free) AND Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)

 

3 – Optimal Combination of Compression Rate and Depth During Cardiopulmonary Resuscitation for Functionally Favorable Survival – JAMA Cardiology (free for a limited period)

Commentaries: Push Hard, Push Fast, Do Not Stop—Optimal Chest Compression Rate and Depth – JAMA Cardiology (free for a limited period) AND Study Details Optimal CPR Speed, Depth – NEJM Journal Watch (free)

Related: Performing CPR? Humming the Macarena Could Help (free)

 

4 – Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk – JAMA (free for a limited period)

Editorial: Gluten and Celiac Disease Risk: Is It Just a Matter of Quantity? (free for a limited period)

Commentaries: Association between coeliac disease risk and gluten intake confirmed – Lund University (free) High Gluten Diet Adds to Risk of Celiac Disease In Genetically Predisposed Children – MedicalResearch.com (free) AND Eating more gluten early in life is tied to children’s higher risk of celiac disease, a study says – CNN (free)

 

5 – Imaging of Pulmonary Hypertension: Pictorial Essay – Chest (free)

Related Guidelines: Therapy for Pulmonary Arterial Hypertension in Adults 2018: Update of the CHEST Guideline and Expert Panel Report (free) AND 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free) AND Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society (free) AND 2018 TSOC guideline focused update on diagnosis and treatment of pulmonary arterial hypertension – Journal of the Formosan Medical Association (free)

 

6 – Key concepts for making informed choices – Nature (free)

 

7 – An augmented reality microscope with real-time artificial intelligence integration for cancer diagnosis – Nature Medicine (free for a limited period)

 

8 – Perspective: Healthcare Needs AI, AI Needs Causality – Forbes (free)

 

9 – Guidelines for the management of common congenital heart diseases: A consensus statement on indications and timing of intervention – Indian Heart Journal (free)

 

10 – Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary: Don’t Use More Than 400 mg of Ibuprofen for Pain Control – NEJM Journal Watch (free for a limited period)

 


[Abstract Only] Study: Diabetes Being Overtreated in Many Vulnerable Clinically Complex Adults

16 Aug, 2019 | 07:50h | UTC

Severe Hypoglycemia Attributable to Intensive Glucose-Lowering Therapy Among US Adults With Diabetes – Mayo Clinic Proceedings (link to abstract – $ for full-text)

Commentary: Too Much of a Good Thing Can Be Dangerous, Finds Researchers Investigating Hypoglycemia – Mayo Clinic (free)

Related Studies: Overtreatment and Deintensification of Diabetic Therapy among Medicare Beneficiaries – Journal of General Internal Medicine (free)  AND Rates of Deintensification of Blood Pressure and Glycemic Medication Treatment Based on Levels of Control and Life Expectancy in Older Patients With Diabetes Mellitus – JAMA Internal Medicine (free)

 


Study: Optimal Combination of Compression Rate and Depth During CPR for Functionally Favorable Survival

15 Aug, 2019 | 08:22h | UTC

Optimal Combination of Compression Rate and Depth During Cardiopulmonary Resuscitation for Functionally Favorable Survival – JAMA Cardiology (free for a limited period)

Commentaries: Push Hard, Push Fast, Do Not Stop—Optimal Chest Compression Rate and Depth – JAMA Cardiology (free for a limited period) AND Study Details Optimal CPR Speed, Depth – NEJM Journal Watch (free)

Related: Performing CPR? Humming the Macarena Could Help (free)

 


Consensus Statement for Enhanced Recovery: Perioperative Opioid Minimization in Opioid-Naïve Patients

15 Aug, 2019 | 08:37h | UTC

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Opioid Minimization in Opioid-Naïve Patients – Anesthesia & Analgesia (free)

Related Position Statements on Perioperative Opioid Therapy: American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Management of Patients on Preoperative Opioid Therapy (free) AND American Society for Enhanced Recovery and Perioperative Quality Initiative-4 Joint Consensus Statement on Persistent Postoperative Opioid Use: Definition, Incidence, Risk Factors, and Health Care System Initiatives (free)

See also: American Society of Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statements (free) AND Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)

 


AAN Guidelines for the Pharmacologic Prevention and Treatment of Migraine in Children and Adolescents

15 Aug, 2019 | 10:27h | UTC

Practice guideline update summary: Pharmacologic treatment for pediatric migraine prevention – Neurology (fee PDF)

See also: Practice guideline update summary: Acute treatment of migraine in children and adolescents – Neurology (free PDF)

Commentaries: AAN issues guidelines for treatment of migraine in children and teens – American Academy of Neurology (free) AND Guidelines Updated on Preventing and Treating Migraine in Children and Teens – NEJM Journal Watch (free)

 


Review: Imaging of Pulmonary Hypertension

15 Aug, 2019 | 07:58h | UTC

Imaging of Pulmonary Hypertension: Pictorial Essay – Chest (free for a limited period)

Related Guidelines: Therapy for Pulmonary Arterial Hypertension in Adults 2018: Update of the CHEST Guideline and Expert Panel Report (free) AND 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free) AND Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society (free) AND 2018 TSOC guideline focused update on diagnosis and treatment of pulmonary arterial hypertension – Journal of the Formosan Medical Association (free)

 


AI-Powered Microscope Can Detect Tumor Cells in Histology Slides

15 Aug, 2019 | 07:41h | UTC

An augmented reality microscope with real-time artificial intelligence integration for cancer diagnosis – Nature Medicine (free for a limited period)

 

Related Commentary on Twitter

 


Study: High Gluten Intake During Childhood May Increase the Risk of Celiac Disease in Genetically Predisposed Children

15 Aug, 2019 | 08:12h | UTC

Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk – JAMA (free for a limited period)

Editorial: Gluten and Celiac Disease Risk: Is It Just a Matter of Quantity? (free for a limited period)

Commentaries: Association between coeliac disease risk and gluten intake confirmed – Lund University (free) High Gluten Diet Adds to Risk of Celiac Disease In Genetically Predisposed Children – MedicalResearch.com (free) AND Eating more gluten early in life is tied to children’s higher risk of celiac disease, a study says – CNN (free)

 


Key Concepts for Making Informed Choices

15 Aug, 2019 | 07:47h | UTC

Key concepts for making informed choices – Nature (free)

 


Perspective: Healthcare Needs AI, AI Needs Causality

15 Aug, 2019 | 07:09h | UTC

Healthcare Needs AI, AI Needs Causality – Forbes (free)

 


[Abstract Only] Randomized Trial: Ibuprofen Administered at Doses of 400, 600, and 800 mg Had Similar Analgesic Efficacy in Acute Pain.

15 Aug, 2019 | 06:58h | UTC

Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary: Don’t Use More Than 400 mg of Ibuprofen for Pain Control – NEJM Journal Watch (free for a limited period)

 

Related Commentary on Twitter

 


Guidelines for the Management of Common Congenital Heart Diseases

15 Aug, 2019 | 07:02h | UTC

Guidelines for the management of common congenital heart diseases: A consensus statement on indications and timing of intervention – Indian Heart Journal (free)

 


Wed August 14 – 10 Stories of The Day!

14 Aug, 2019 | 10:46h | UTC

 

1 – Two Ebola drugs show promise amid ongoing outbreak – Nature (free)

See also: Ebola drugs show ‘90% survival rate’ in breakthrough trial – BBC (free) AND AND 2 Experimental Ebola Drugs Saved Lives In Congo Outbreak – NPR (free) AND A Cure for Ebola? Two New Treatments Prove Highly Effective in Congo – The New York Times (10 articles per month are free)

 

2 – Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia – JAMA (free for a limited period)

Related Research: Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions – JAMA (free for a limited period)

Editorial: Blood Pressure, Brain Volume and White Matter Hyperintensities, and Dementia Risk (free for a limited period)

Video Summary: Hypertension and Dementia (free)

Commentary: Expert reaction to two studies looking at blood pressure and dementia – Science Media Centre (free)

 

3 – Association Between Long-term Exposure to Ambient Air Pollution and Change in Quantitatively Assessed Emphysema and Lung Function – JAMA (free for a limited period)

Video Abstract: Ambient Air Pollution and Change in Emphysema and Lung Function (free)

Commentaries: Air Pollution May Be As Harmful To Your Lungs As Smoking Cigarettes, Study Finds – NPR (free) AND Study finds link between long-term exposure to air pollution and emphysema – NIH News Releases (free)

 

4 – Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text)

Related Study: Colonoscopy Adenoma Findings and Long-term Colorectal Cancer Incidence (free study, commentaries and guidelines on the subject)

Source: NEJM Journal Watch ($)

 

5 – Update on the contraceptive contraindications – Journal of Gynecology Obstetrics and Human Reproduction (free)

Related Guidelines: WHO Medical eligibility criteria for contraceptive use (free PDF) AND US Medical Eligibility Criteria for Contraceptive Use (free) AND UK Medical Eligibility Criteria for Contraceptive Use (free)

 

6 – Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review – JAMA (free for a limited period)

 

7 – Mechanisms for hemodynamic instability related to renal replacement therapy: a narrative review – Intensive Care Medicine (free)

Related: Interventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients: a systematic review – Critical Care (free)

 

8 – The entire human brain in ‘unprecedented’ detail, thanks to powerful MRI – STAT (free)

 

9 – Draft Recommendation Statement: Screening for Illicit Drug Use, Including Nonmedical Use of Prescription Drugs: Screening – U.S. Preventive Services Task Force (free)

Commentaries: For the first time, U.S. panel recommends screening adults for illicit drug use – STAT (free) AND Screen All Adult Patients for Drug Abuse, National Panel Urges – The New York Times (10 articles per month are free) AND

 

10 – Roles of cyberbullying, sleep, and physical activity in mediating the effects of social media use on mental health and wellbeing among young people in England: a secondary analysis of longitudinal data – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)

Commentaries: Social media use may harm teens’ mental health by disrupting positive activities, study says – CNN (free) AND Social-media use ‘disrupting teen sleep and exercise’ – BBC (free) AND Expert reaction to study on social media use and the role of cyberbullying, sleep and physical activity in the wellbeing in young people – Science Media Centre (free) AND Social Media’s Ill Effects in Teen Girls: 3 Factors Play Large Role – NEJM Journal Watch (free)

 


Experimental Ebola Drugs Show 90% Survival Rate

14 Aug, 2019 | 10:44h | UTC

Two Ebola drugs show promise amid ongoing outbreak – Nature (free)

See also: Ebola drugs show ‘90% survival rate’ in breakthrough trial – BBC (free) AND 2 Experimental Ebola Drugs Saved Lives In Congo Outbreak – NPR (free) AND A Cure for Ebola? Two New Treatments Prove Highly Effective in Congo – The New York Times (10 articles per month are free)

 


Study: Midlife to Late-Life Blood Pressure Patterns and Incident Dementia

14 Aug, 2019 | 10:33h | UTC

Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia – JAMA (free for a limited period)

Related Research: Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions – JAMA (free for a limited period)

Editorial: Blood Pressure, Brain Volume and White Matter Hyperintensities, and Dementia Risk (free for a limited period)

Video Summary: Hypertension and Dementia (free)

Commentary: Expert reaction to two studies looking at blood pressure and dementia – Science Media Centre (free)

 


Study: Ambient Air Pollution and Change in Emphysema and Lung Function

14 Aug, 2019 | 08:41h | UTC

Association Between Long-term Exposure to Ambient Air Pollution and Change in Quantitatively Assessed Emphysema and Lung Function – JAMA (free for a limited period)

Video Abstract: Ambient Air Pollution and Change in Emphysema and Lung Function (free)

Commentaries: Air Pollution May Be As Harmful To Your Lungs As Smoking Cigarettes, Study Finds – NPR (free) AND Study finds link between long-term exposure to air pollution and emphysema – NIH News Releases (free)

 


[Abstract Only] Cohort Study: Individuals with 1 or 2 Small Adenomas at Baseline Screening Colonoscopy Have a Similar Risk of Advanced Neoplasia over 10 years as Individuals with no Baseline Adenomas

14 Aug, 2019 | 08:34h | UTC

Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text)

Related Study: Colonoscopy Adenoma Findings and Long-term Colorectal Cancer Incidence (free study, commentaries and guidelines on the subject)

Source: NEJM Journal Watch ($)

 


Review: Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications

14 Aug, 2019 | 08:29h | UTC

Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review – JAMA (free for a limited period)

 


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