Archives
Review: Metabolic and Endocrine Consequences of Bariatric Surgery
16 Oct, 2019 | 08:36h | UTCMetabolic and Endocrine Consequences of Bariatric Surgery – Frontiers in Endocrinology (free)
Tue October 15 – 10 Stories of The Day!
15 Oct, 2019 | 11:09h | UTC
Commentaries: CRASH-3: a win for patients with traumatic brain injury – The Lancet (free) AND Global trial is first clear evidence that a widely available drug reduces head injury deaths – London School of Hygiene & Tropical Medicine (free) AND PulmCrit- Tranexamic acid for traumatic brain injury (CRASH3) (free) AND CRASH-3! – Emergency Medicine Literature of Note (free) AND Head injuries: Cheap drug ‘could save thousands of lives a year’ – BBC (free) AND Common drug could prevent thousands of head injury deaths – The Guardian (free)
Related: Evidence Review: Tranexamic Acid (TXA) for Everything that Bleeds? (free resources on the subject)
2 – Conservative Oxygen Therapy during Mechanical Ventilation in the ICU – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: No clear benefit from conservative oxygen in mechanical ventilation – CHEST Physician (free) AND Trial: No Need for Intensive Oxygen in the ICU – MedPage Today (free registration required)
Related: The management of diabetic foot: A clinical practice guideline by the Society for Vascular Surgery in collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine (free) AND Diabetic foot – The BMJ (free) AND Diagnosis and Management of Diabetic Foot Complications – American Diabetes Association (free) AND Prevention, assessment, diagnosis and management of diabetic foot based on clinical practice guidelines: A systematic review – Medicine (free)
4 – Comparative Efficacy of Interventions for Aggressive and Agitated Behaviors in Dementia: A Systematic Review and Network Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia – St. Michael’s Hospital (free) AND To ease dementia agitation, drugs may not be best option – Reuters (free)
5 – Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Rivaroxaban Not Noninferior to VKAs for Antiphospholipid Antibody Syndrome – NEJM Journal Watch (free) AND DOAC Disappoints in Thrombotic Autoimmune Disorder – MedPage Today (free registration required)
Commentary: Ingestible sensor allows patients to be independent but still supported during TB treatment – Specialists in Global Health (free)
See also: Episodes List
8 – Management of Itch in the Elderly: A Review – Dermatology and Therapy (free)
9 – Youth suicide attempts often involve over-the-counter painkillers – Reuters (free)
Original Study: Suicide attempts by self-poisoning in the United States among 10–25 year olds from 2000 to 2018: substances used, temporal changes and demographics – Journal of Clinical Toxicology (free)
10 – Oral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary: RCT – APAP Only vs APAP-Ibuprofen-Codeine Combo – Journal Feed (free)
Practice-Changing: Tranexamic Acid Reduces the Risk of Head Injury-related Death in Patients with Mild-to-moderate Head Injury
15 Oct, 2019 | 10:56h | UTCCommentaries: CRASH-3: a win for patients with traumatic brain injury – The Lancet (free) AND Global trial is first clear evidence that a widely available drug reduces head injury deaths – London School of Hygiene & Tropical Medicine (free) AND PulmCrit- Tranexamic acid for traumatic brain injury (CRASH3) (free) AND CRASH-3! – Emergency Medicine Literature of Note (free) AND Head injuries: Cheap drug ‘could save thousands of lives a year’ – BBC (free) AND Common drug could prevent thousands of head injury deaths – The Guardian (free)
Related: Evidence Review: Tranexamic Acid (TXA) for Everything that Bleeds? (free resources on the subject)
[Abstract Only] Meta-Analysis: Comparative Efficacy of Interventions for Aggressive and Agitated Behaviors in Dementia
15 Oct, 2019 | 10:35h | UTCComparative Efficacy of Interventions for Aggressive and Agitated Behaviors in Dementia: A Systematic Review and Network Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia – St. Michael’s Hospital (free) AND To ease dementia agitation, drugs may not be best option – Reuters (free)
[Abstract Only] Randomized Trial: Similar Outcomes with Conservative Oxygen Therapy vs. Usual Oxygen Therapy During Mechanical Ventilation
15 Oct, 2019 | 10:55h | UTCConservative Oxygen Therapy during Mechanical Ventilation in the ICU – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: No clear benefit from conservative oxygen in mechanical ventilation – CHEST Physician (free) AND Trial: No Need for Intensive Oxygen in the ICU – MedPage Today (free registration required)
Updated NICE Guideline: Diabetic Foot Problems
15 Oct, 2019 | 10:47h | UTCRelated: The management of diabetic foot: A clinical practice guideline by the Society for Vascular Surgery in collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine (free) AND Diabetic foot – The BMJ (free) AND Diagnosis and Management of Diabetic Foot Complications – American Diabetes Association (free) AND Prevention, assessment, diagnosis and management of diabetic foot based on clinical practice guidelines: A systematic review – Medicine (free)
[Abstract Only] Randomized Trial: DOAC Not as Good as Vitamin K Antagonist for Anticoagulation in Antiphospholipid Syndrome
15 Oct, 2019 | 10:32h | UTCRivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Rivaroxaban Not Noninferior to VKAs for Antiphospholipid Antibody Syndrome – NEJM Journal Watch (free) AND DOAC Disappoints in Thrombotic Autoimmune Disorder – MedPage Today (free registration required)
Study: Youth Suicide Attempts Often Involve Over-the-counter Painkillers
15 Oct, 2019 | 10:16h | UTCYouth suicide attempts often involve over-the-counter painkillers – Reuters (free)
Original Study: Suicide attempts by self-poisoning in the United States among 10–25 year olds from 2000 to 2018: substances used, temporal changes and demographics – Journal of Clinical Toxicology (free)
Randomized Trial: Wirelessly Observed Therapy vs. Directly Observed Therapy to Confirm Tuberculosis Treatment Adherence
15 Oct, 2019 | 10:31h | UTCCommentary: Ingestible sensor allows patients to be independent but still supported during TB treatment – Specialists in Global Health (free)
Podcast: Osteoarthritis Master Class
15 Oct, 2019 | 10:22h | UTCSee also: Episodes List
Review: Management of Itch in the Elderly
15 Oct, 2019 | 10:17h | UTCManagement of Itch in the Elderly: A Review – Dermatology and Therapy (free)
[Abstract Only] Randomized Trial: Oral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries
15 Oct, 2019 | 10:14h | UTCOral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary: RCT – APAP Only vs APAP-Ibuprofen-Codeine Combo – Journal Feed (free)
Guidelines for the Surgical Management of Enteral Stomas in Adults
15 Oct, 2019 | 10:12h | UTC
Special Issue: Neonatal ECMO in 2019
15 Oct, 2019 | 10:11h | UTCHomepage: Neonatal ECMO in 2019: Where Are We Now? Where Next? – Frontiers in Pediatrics (free articles)
– Anticoagulation in Neonatal ECMO: An Enigma Despite a Lot of Effort!
– Drug Disposition and Pharmacotherapy in Neonatal ECMO: From Fragmented Data to Integrated Knowledge
– Neonatal Cardiac ECMO in 2019 and Beyond
– Extracorporeal Membrane Oxygenation in Congenital Diaphragmatic Hernia
Systematic Review: Evaluation of E-learning for Medical Education in Low- and Middle-income Countries
15 Oct, 2019 | 10:13h | UTC
Position Statement: Treatment of Hyperglycemia in Patients with Type 2 Diabetes and Impaired Renal Function
15 Oct, 2019 | 08:38h | UTCRelated: New ADA 2020 Guidelines for the Management of Diabetes (free)
A Fairer Way Forward for AI in Health Care
15 Oct, 2019 | 08:45h | UTCA fairer way forward for AI in health care – Nature (free)
[Abstract Only] Randomized Trial: Treatments for Multiple Sclerosis Compared
15 Oct, 2019 | 08:35h | UTCSafety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (RADIANCE): a multicentre, randomised, 24-month, phase 3 trial – The Lancet Neurology (link to abstract – $ for full-text)
Commentary: Measure From RADIANCE Data Suggests Ozanimod More Effective in Slowing MS Disease Activity – AJMC (free)
Source: EvidenceAlerts
[Abstract Only] Randomized Trial: Anti-CD19 Monoclonal Antibody Tested for the Treatment of Neuromyelitis Optica Spectrum Disorder
15 Oct, 2019 | 08:29h | UTCInebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Anti-CD19 MAb Trial Halted Early for Benefit in NMO – Medscape (free registration required)
Cardiovascular Risk in Fatty Liver Disease: The Liver-Heart Axis—Literature Review
15 Oct, 2019 | 08:23h | UTC
Extrahepatic Complications of Non-alcoholic Fatty Liver Disease
15 Oct, 2019 | 08:14h | UTC
Mon October 14 – 10 Stories of The Day!
14 Oct, 2019 | 10:26h | UTC
Commentaries: Vaping-related illness has a new name: EVALI – STAT (free) AND No Drop in Vaping Cases, C.D.C. Says – The New York Times (free) AND CDC Updates Guidance on Vaping-Linked Illness, Coins Term EVALI – Medscape (free registration required)
Related: Vaping Illness Update: FDA Warns Public to Stop Using Tetrahydrocannabinol (THC)-Containing Vaping Products and Any Vaping Products Obtained Off the Street – U.S. Food & Drug Administration (free) AND CDC Intensifies Warnings About Vaping Illness As Cases Top 1,000 – NPR (free) AND CDC Report: 76.9% of Patients with Vaping-related Lung Illnesses Used a THC-Containing Product (free) AND Preliminary Report: Pulmonary Illness Related to E-Cigarette Use (free)
2 – Offline: Touch—the first language – The Lancet (free)
Related: Of Slide Rules and Stethoscopes: AI and the Future of Doctoring – The Hastings Center Report (free)
3 – Bacon Rashers, Statistics, and Controversy – The BMJ Opinion (free)
Original Article: Guideline: It Is NOT Necessary to Reduce Red and Processed Meat Consumption (free guideline and systematic reviews)
Related: Meat’s Bad for You! No, It’s Not! How Experts See Different Things in the Data – The New York Times (10 articles per month are free) AND Is eating beef healthy? The new fight raging in nutrition science, explained. – Vox (free) AND Scientist Who Discredited Meat Guidelines Didn’t Report Past Food Industry Ties – The New York Times (10 articles per month are free)
Related: Meta-Analysis: Assessment of Therapeutic Interventions and Lung Protective Ventilation in Patients with Moderate to Severe Acute Respiratory Distress Syndrome (free meta-analysis and guidelines on the subject) AND Research: ECMO versus Prone Position in ARDS (link to abstract) AND Prone Positioning in Severe Acute Respiratory Distress Syndrome – New England Journal of Medicine (free)
5 – Effect of a fluid bolus on cardiovascular collapse among critically ill adults undergoing tracheal intubation (PrePARE): a randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Source: Critical Care Reviews Newsletter
Source: EvidenceAlerts
Long-Term Evolution of Premature Coronary Artery Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Recurrent Events Common Among Young Patients With CAD – TCTMD (free) AND Early MI Linked to High Recurrent Events, Mortality – Medscape (free registration required)
News Release: Radiology organizations publish statement on ethics of AI in Radiology – Radiological Society of North America (RSNA) (free)
Study: Non-alcoholic Fatty Liver Disease and Risk of Incident Acute Myocardial Infarction and Stroke
15 Oct, 2019 | 08:08h | UTC
Perspective – Offline: Touch—The First Language
14 Oct, 2019 | 08:39h | UTCOffline: Touch—the first language – The Lancet (free)
Related: Of Slide Rules and Stethoscopes: AI and the Future of Doctoring – The Hastings Center Report (free)
Related Commentary on Twitter
"The physical examination seems to have become an anachronism, a vestigial remnant, of clinical care."
"The avoidance of touch is bad medicine." https://t.co/Zdq63syG0e by @richardhorton1 @TheLancet
like the plea for this in #DeepMedicine to make #healthcare more human again pic.twitter.com/0bb9arjWdu— Eric Topol (@EricTopol) October 11, 2019
Opinion: Bacon Rashers, Statistics, and Controversy
14 Oct, 2019 | 08:37h | UTCBacon Rashers, Statistics, and Controversy – The BMJ Opinion (free)
Original Article: Guideline: It Is NOT Necessary to Reduce Red and Processed Meat Consumption (free guideline and systematic reviews)
Related: Meat’s Bad for You! No, It’s Not! How Experts See Different Things in the Data – The New York Times (10 articles per month are free) AND Is eating beef healthy? The new fight raging in nutrition science, explained. – Vox (free) AND Scientist Who Discredited Meat Guidelines Didn’t Report Past Food Industry Ties – The New York Times (10 articles per month are free)