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[Abstract Only] Meta-Analysis: Lithium Exposure During Pregnancy and the Postpartum Period

23 Oct, 2019 | 07:51h | UTC

Lithium Exposure During Pregnancy and the Postpartum Period: A Systematic Review and Meta-Analysis of Safety and Efficacy Outcomes – The American Journal of Psychiatry (link to abstract – $ for full-text)

Commentary: Prescribing Lithium During Pregnancy Requires Careful Balancing of Benefits, Risks – Psychiatric News Alert (free)

 


[Abstract Only] Meta-Analysis: Incisional Negative Pressure Wound Therapy vs. Control Dressings for the Prevention of Postoperative Wound Complications

23 Oct, 2019 | 07:54h | UTC

Meta-analysis, Meta-regression, and GRADE Assessment of Randomized and Nonrandomized Studies of Incisional Negative Pressure Wound Therapy Versus Control Dressings for the Prevention of Postoperative Wound Complications – Annals of Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts

 


Randomized Trial: Routine Early Occupational Intervention Unnecessary to Treat Back Pain

23 Oct, 2019 | 07:50h | UTC

Early occupational intervention for people with low back pain in physically demanding jobs: A randomized clinical trial – PLOS Medicine (free)

Commentary: Occupational Intervention Unnecessary to Treat Back Pain – JAMA (free)

 


Hemolytic Uremic Syndrome: Diagnosis and Management

23 Oct, 2019 | 07:24h | UTC

Haemolytic uremic syndrome: diagnosis and management – F1000Research (free)

Source: Critical Care Reviews Newsletter

 


Review: Differential Diagnosis of Multiple Sclerosis and Other Inflammatory CNS Diseases

23 Oct, 2019 | 07:25h | UTC

Differential diagnosis of multiple sclerosis and other inflammatory CNS diseases – Multiple Sclerosis and Related Disorders (free)

 


Review: Emerging Drug Classes and Their Potential Use in Hypertension

23 Oct, 2019 | 07:23h | UTC

Emerging Drug Classes and Their Potential Use in Hypertension – Hypertension (free for a limited period)

 


[Abstract Only] Study: Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy

23 Oct, 2019 | 07:22h | UTC

Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy – Arthritis & Rheumatology (link to abstract – $ for full-text)

Commentaries: Hydroxychloroquine Blood Levels Predict Retinopathy Risk in Lupus – Physician’s Weekly (free) AND Monitoring blood hydroxychloroquine levels beneficial in SLE – Medwire News (free)

 


Review: Treating Restless Legs Syndrome in the Context of Sleep Disordered Breathing Comorbidity

23 Oct, 2019 | 07:19h | UTC

Treating restless legs syndrome in the context of sleep disordered breathing comorbidity – European Respiratory Review (free)

 


Comorbidities in Idiopathic Pulmonary Fibrosis: An Underestimated Issue

23 Oct, 2019 | 07:20h | UTC

Comorbidities in idiopathic pulmonary fibrosis: an underestimated issue – European Respiratory Review (free)

 


Review: Pulmonary Complications of Immune Checkpoint Inhibitors in Patients with Nonsmall Cell Lung Cancer

23 Oct, 2019 | 07:18h | UTC

Pulmonary complications of immune checkpoint inhibitors in patients with nonsmall cell lung cancer – European Respiratory Review (free)

Related: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)

 


Update on Management of Stable COPD

22 Oct, 2019 | 08:01h | UTC

Update on management of stable chronic obstructive pulmonary disease – Journal of Thoracic Disease (free)

Related Guidelines: 2019 Global Strategy for Prevention, Diagnosis and Management of COPD – GOLD Reports 2019 (free PDF) AND Chronic obstructive pulmonary disease in over 16s: diagnosis and management – National Institute for Health and Care Excellence (free)

 


Tue October 22 – 10 Stories of The Day!

22 Oct, 2019 | 08:49h | UTC

 

1 – Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations from the International Consensus Group – Annals of Internal Medicine (free)

Commentary: Guideline on Managing Acute Upper Gastrointestinal Bleeding Updated – NEJM Journal Watch (free)

 

2 – Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management – National Institute for Health and Care Excellence (free)

 

3 – Neurodegenerative Disease Mortality among Former Professional Soccer Players – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Dementia in football: Ex-players three and a half times more likely to die of condition – BBC (free) AND Study shows more thinking problems in former pro soccer players – Reuters (free)

 

4 – Pan-viral serology implicates enteroviruses in acute flaccid myelitis – Nature (link to abstract – $ for full-text)

Commentaries: ‘Missing’ Virus Detected in Dozens of Children Paralyzed by Polio-Like Illness – UC San Francisco (free) AND What Causes a Mysterious Paralysis in Children? Researchers Find Viral Clues – The New York Times (10 articles per month are free) AND Virus could be the cause of mysterious polio-like illness AFM, study says – CNN (free)

 

5 – Episiotomy use among vaginal deliveries and the association with anal sphincter injury: a population-based retrospective cohort study – Canadian Medical Association Journal (free)

News Release: Episiotomy may be beneficial in reducing severe perineal tears among forceps and vacuum deliveries – Canadian Medical Association Journal (free)

 

6 – #178 Tuberculosis Updates with Laila Woc-Colburn MD – The Curbsiders Internal Medicine Podcast (free audio)

 

7 – Super-precise new CRISPR tool could tackle a plethora of genetic diseases – Nature News (free)

Original Article: Search-and-replace genome editing without double-strand breaks or donor DNA – Nature (link to abstract – $ for full-text)

See also: New CRISPR genome editing system offers a wide range of versatility in human cells – Broad Institute of MIT and Harvard (free) AND Prime editing: DNA tool could correct 89% of genetic defects – BBC (free) AND New CRISPR tool has the potential to correct almost all disease-causing DNA glitches, scientists report – STAT (free)

Related: Simple guide to CRISPR, one of the biggest science stories of the decade – VOX (free)

 

8 – Update on management of stable chronic obstructive pulmonary disease – Journal of Thoracic Disease (free)

Related Guidelines: 2019 Global Strategy for Prevention, Diagnosis and Management of COPD – GOLD Reports 2019 (free PDF) AND Chronic obstructive pulmonary disease in over 16s: diagnosis and management – National Institute for Health and Care Excellence (free)

 

9 – Effect of the Tailored, Family-Involved Hospital Elder Life Program on Postoperative Delirium and – Function in Older Adults: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Commentaries: Including the Family in Perioperative Care of Older Adults—A Call for HELP – JAMA Internal Medicine (free for a limited period) AND Family members can help reduce the incidence of post-operative delirium by up to 16.8% – News Medical (free)

 

10 – Effect of Depression Screening After Acute Coronary Syndromes on Quality of Life: The CODIACS-QoL Randomized Clinical Trial – JAMA Internal Medicine (free for a limited Period)

Commentary: Depression Intervention Flops for Heart Attack Survivors – MedPage Today (free registration required)

 


NICE Guideline: Gastro-esophageal Reflux Disease and Dyspepsia in Adults

22 Oct, 2019 | 08:11h | UTC

Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management – National Institute for Health and Care Excellence (free)

 


Guideline: Management of Nonvariceal Upper Gastrointestinal Bleeding

22 Oct, 2019 | 08:13h | UTC

Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations from the International Consensus Group – Annals of Internal Medicine (free)

Commentary: Guideline on Managing Acute Upper Gastrointestinal Bleeding Updated – NEJM Journal Watch (free)

 


[Abstract Only] Study: Neurodegenerative Disease Mortality Increased Among Former Professional Soccer Players

22 Oct, 2019 | 08:09h | UTC

Neurodegenerative Disease Mortality among Former Professional Soccer Players – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Dementia in football: Ex-players three and a half times more likely to die of condition – BBC (free) AND Study shows more thinking problems in former pro soccer players – Reuters (free)

 

Related Commentary on Twitter

 


Study: Episiotomy May be Beneficial in Reducing Severe Perineal Tears Among Forceps and Vacuum deliveries

22 Oct, 2019 | 08:06h | UTC

Episiotomy use among vaginal deliveries and the association with anal sphincter injury: a population-based retrospective cohort study – Canadian Medical Association Journal (free)

News Release: Episiotomy may be beneficial in reducing severe perineal tears among forceps and vacuum deliveries – Canadian Medical Association Journal (free)

 


[Abstract Only] Study: Pan-viral Serology Implicates Enteroviruses in Acute Flaccid Myelitis

22 Oct, 2019 | 08:08h | UTC

Pan-viral serology implicates enteroviruses in acute flaccid myelitis – Nature (link to abstract – $ for full-text)

Commentaries: ‘Missing’ Virus Detected in Dozens of Children Paralyzed by Polio-Like Illness – UC San Francisco (free) AND What Causes a Mysterious Paralysis in Children? Researchers Find Viral Clues – The New York Times (10 articles per month are free) AND Virus could be the cause of mysterious polio-like illness AFM, study says – CNN (free)

 


[Abstract Only] Super-precise New CRISPR Tool Could Tackle a Plethora of Genetic Diseases

22 Oct, 2019 | 08:03h | UTC

Super-precise new CRISPR tool could tackle a plethora of genetic diseases – Nature News (free)

Original Article: Search-and-replace genome editing without double-strand breaks or donor DNA – Nature (link to abstract – $ for full-text)

See also: New CRISPR genome editing system offers a wide range of versatility in human cells – Broad Institute of MIT and Harvard (free) AND Prime editing: DNA tool could correct 89% of genetic defects – BBC (free) AND New CRISPR tool has the potential to correct almost all disease-causing DNA glitches, scientists report – STAT (free)

Related: Simple guide to CRISPR, one of the biggest science stories of the decade – VOX (free)

 


Podcast: Tuberculosis Updates

22 Oct, 2019 | 08:05h | UTC

#178 Tuberculosis Updates with Laila Woc-Colburn MD – The Curbsiders Internal Medicine Podcast (free audio)

 


Systematic Review: Pharmacologic and Nonpharmacologic Therapies in Adult Patients with Exacerbation of COPD

20 Oct, 2019 | 23:11h | UTC

Pharmacologic and Nonpharmacologic Therapies in Adult Patients with Exacerbation of COPD – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF)

Related: NICE Guideline: Acute Exacerbation of COPD (free)

 


Randomized Trial: Depression Screening Does Not Improve Quality of Life After Acute Coronary Syndromes

22 Oct, 2019 | 07:56h | UTC

Effect of Depression Screening After Acute Coronary Syndromes on Quality of Life: The CODIACS-QoL Randomized Clinical Trial – JAMA Internal Medicine (free for a limited Period)

Commentary: Depression Intervention Flops for Heart Attack Survivors – MedPage Today (free registration required)

 


Randomized Trial: Including the Family in Perioperative Care of Older Adults Can Reduce Postoperative Delirium

22 Oct, 2019 | 07:59h | UTC

Effect of the Tailored, Family-Involved Hospital Elder Life Program on Postoperative Delirium and – Function in Older Adults: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Commentaries: Including the Family in Perioperative Care of Older Adults—A Call for HELP – JAMA Internal Medicine (free for a limited period) AND Family members can help reduce the incidence of post-operative delirium by up to 16.8% – News Medical (free)

 


Meta-Analysis: Interleukin Inhibitors Increase the Risk of Infections and Cancer in Patients with Rheumatologic Diseases

22 Oct, 2019 | 07:38h | UTC

Risk of Infections and Cancer in Patients with Rheumatologic Diseases Receiving Interleukin Inhibitors: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentary: Interleukin Targeted Biologics Increase Risks of Infection – RheumNow (free)

 


Randomized Trial: Fibrinogen Concentrate vs. Cryoprecipitate for the Treatment of Bleeding in Cardiac Surgery

22 Oct, 2019 | 07:36h | UTC

Effect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery: The FIBRES Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Should Fibrinogen Concentrate Replace Cryoprecipitate in Cardiac Surgery? (free for a limited period)

 


[Abstract Only] Study: Potato as Effective as Carbohydrate Gels to Support Prolonged Cycling Performance

22 Oct, 2019 | 07:35h | UTC

Potato ingestion is as effective as carbohydrate gels to support prolonged cycling performance – Journal of Applied Physiology (link to abstract – $ for full-text)

Commentaries: Potato as effective as carbohydrate gels for boosting athletic performance, study finds – University of Illinois (free) AND Performance-enhancing with … potatoes! – News Medical (free)

 


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