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Meta-Analysis: Which Modes of Exercise are Most Effective for Treating Low Back Pain?

4 Nov, 2019 | 01:19h | UTC

Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis – British Journal of Sports Medicine (free)

 

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Randomized Trial: Naproxen vs. Colchicine for the Treatment of Gout Flares in Primary Care

4 Nov, 2019 | 01:13h | UTC

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care – Annals of Rheumatic Diseases (free)

 

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[Abstract Only] Randomized Trial: Therapeutic-induced Hypertension May Improve Outcomes in Selected Patients with Noncardioembolic Acute Stroke

4 Nov, 2019 | 01:10h | UTC

Therapeutic-induced hypertension in patients with noncardioembolic acute stroke – Neurology (link to abstract – $ for full-text)

 

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Opinion – “The EMR has changed the doctor-patient duet into a ménage-à-trois”

4 Nov, 2019 | 01:08h | UTC

The EMR has changed the doctor-patient duet into a ménage-à-trois – STAT (free)

Related: How Tech Can Turn Doctors Into Clerical Workers – The New York Times Magazine (10 articles per month are free) AND Date Night with the EHR – NEJM Catalyst (free) AND Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians (free) AND Care-Centered Clinical Documentation in the Digital Environment: Solutions to Alleviate Burnout – National Academy of Medicine (free) AND To Combat Physician Burnout and Improve Care, Fix the Electronic Health Record – Harvard Business Review (a few articles per month are free)

 

Podcast: Emerging Applications for Ketamine

4 Nov, 2019 | 00:50h | UTC

Emerging Applications for Ketamine – JAMA (free audio)

Related Resources:

Ketamine for Pain: Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists (free)

Ketamine for Depression: Ketamine and depression: a narrative review – Drug Design, Development and Therapy (free)

 

Alex Nowbar’s weekly review—1 November 2019

4 Nov, 2019 | 00:41h | UTC

Alex Nowbar’s weekly review, 1 November 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 

Review: Vaccines for International Travel

4 Nov, 2019 | 00:28h | UTC

Vaccines for International Travel – Mayo Clinic Proceedings (free)

See also: Just Released. 2020 Edition of CDC Traveler’s Health Yellow Book (free resources)

 

AAP Clinical Report: Soccer Injuries in Children and Adolescents

3 Nov, 2019 | 20:18h | UTC

Soccer Injuries in Children and Adolescents – Pediatrics (free)

News Release: American Academy of Pediatrics Outlines Soccer Injuries and Prevention Techniques in Clinical Report – American Academy of Pediatrics (free)

 

Cohort Study: Incidence of Acute Kidney Injury in Patients Receiving Immune Checkpoint Inhibitors

4 Nov, 2019 | 00:24h | UTC

The Incidence, Causes, and Risk Factors of Acute Kidney Injury in Patients Receiving Immune Checkpoint Inhibitors – Clinical Journal of the American Society of Nephrology (free for a limited period)

News Release: Study Examines Kidney Injury in Patients Taking Immunotherapy Cancer Medications – American Society of Nephrology (free)

Related: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)

 

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https://twitter.com/CJASN/status/1190342954830966785

 

AAP Clinical Report: Updates on an At-Risk Population: Late-Preterm and Early-Term Infants

3 Nov, 2019 | 20:20h | UTC

Updates on an At-Risk Population: Late-Preterm and Early-Term Infants – Pediatrics (free)

 

Systematic Review: Interventions for Prodromal Stage of Psychosis

3 Nov, 2019 | 20:12h | UTC

Interventions for prodromal stage of psychosis – Cochrane Library (free)

Summary: Early interventions for people at risk of developing psychosis – Cochrane Library (free)

 

Perspective: The Oncology Care Model—Why It Works and Why It Could Work Better: Accounting for Novel Therapies in Value-Based Payment

3 Nov, 2019 | 19:56h | UTC

The Oncology Care Model—Why It Works and Why It Could Work Better: Accounting for Novel Therapies in Value-Based Payment – JAMA Oncology (free for a limited period)

 

AAP Policy Statement: Mental Health Competencies for Pediatric Practice

3 Nov, 2019 | 20:13h | UTC

Mental Health Competencies for Pediatric Practice – Pediatrics (free)

Technical Report: Achieving the Pediatric Mental Health Competencies – Pediatrics (free)

News Release: American Academy of Pediatrics Provides Guidance on Helping Children With Mental Health Challenges – American Academy of Pediatrics (free)

 

Observational Study: Perioperative Disposable Jackets Not Associated with Reductions in Surgical Site Infections

3 Nov, 2019 | 20:03h | UTC

Association of Disposable Perioperative Jackets With Surgical Site Infections in a Large Multicenter Health Care Organization – JAMA Surgery (free for a limited period)

 

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AAP Policy Statement: The Use of Nonnutritive Sweeteners in Children

3 Nov, 2019 | 20:15h | UTC

The Use of Nonnutritive Sweeteners in Children – Pediatrics (free)

News Release: Nonnutritive sweetener use in children – American Academy of Pediatrics (free)

Commentary: AAP: Too Much Unknown About Sugar Substitutes’ Effects on Kids – MedPage Today (free registration required)

 

Pay for Relationship: A Novel Solution to the Primary Care Crisis

3 Nov, 2019 | 19:53h | UTC

Pay for Relationship: A Novel Solution to the Primary Care Crisis – NEJM Catalyst (free)

 

Study: Status of Care for end Stage Kidney Disease in Countries and Regions Worldwide

3 Nov, 2019 | 19:39h | UTC

Status of care for end stage kidney disease in countries and regions worldwide: international cross sectional survey – The BMJ (free)

 

New Enhanced Recovery After Surgery (ERAS) Guideline: Perioperative Care in Total Hip Replacement and Total Knee Replacement Surgery

1 Nov, 2019 | 10:43h | UTC

Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations – Acta Orthopaedica (free)

Related: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)

 

Randomized Trial: Severe Energy Restriction Associated with Increased Bone Loss when Compared with Moderate Energy Restriction

3 Nov, 2019 | 19:48h | UTC

Effect of Weight Loss via Severe vs Moderate Energy Restriction on Lean Mass and Body Composition Among Postmenopausal Women With Obesity: The TEMPO Diet Randomized Clinical Trial – JAMA Network Open (free)

Commentary: Total Meal Replacement Diets Effective for Weight Loss, But Can Lead To Bone Loss – MedicalResearch.com (free)

 

Fri November 1 – 10 Stories of The Day!

1 Nov, 2019 | 10:55h | UTC

 

1 – Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations – Acta Orthopaedica (free)

Related: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)

 

2 – Report: The Power of Cities: Tackling Noncommunicable Diseases and Road Traffic Injuries – World Health Organization (free PDF)

News Release: New WHO report to bolster efforts to tackle leading causes of urban deaths – World Health Organization (free)

 

3 – Short- vs. long-term dual antiplatelet therapy in secondary prevention for ischaemic stroke: a network metanalysis – European Heart Journal – Quality of Care and Clinical Outcomes (free)

Related Study: Dual Antiplatelet Therapy Should be Used for 21 Days After Minor Ischemic Stroke or High-risk Transient Ischemic Attack (link to abstract)

Related Guideline: Dual Antiplatelet Therapy for Acute High-Risk TIA and Minor Ischemic Stroke – The BMJ (free)

 

4 – Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele – New England Journal of Medicine (link to abstract – $ for full-text)

Editorial: Realizing the Dream of Molecularly Targeted Therapies for Cystic Fibrosis (free)

Related Research: Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Three-drug combo improves lung function in most common genetic form of cystic fibrosis – UT Southwestern Medical Center (free)

 

5 – Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens – Science (free for a limited period)

Related Research: Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles – Science Immunology (free for a limited period)

Commentaries: How measles infections can wipe away immunity to other diseases – STAT (free) AND Measles wipe immune system’s memory of other illnesses, studies find – CNN (free) AND Measles Virus May Wipe Out Immune Protection For Other Diseases – NPR (free) AND Measles vaccines protect against more than just measles. Here’s how. – National Geographic (free) AND Measles Infection Could Leave Kids Vulnerable to Other Diseases – Scientific American (free)

 

6 – Quantifying risks and interventions that have affected the burden of lower respiratory infections among children younger than 5 years: an analysis for the Global Burden of Disease Study 2017 – The Lancet Infectious Diseases (free)

Invited Commentary: Trends in the global burden of paediatric lower respiratory infections (free)

News Release: New study finds one in seven child deaths result from pneumonia, the flu, and other lower respiratory infections – Institute for Health Metrics and Evaluation (free)

Related: Global Burden of Pneumonia in Children Younger than 5 Years (free)

 

7 – Quantifying risks and interventions that have affected the burden of diarrhoea among children younger than 5 years: an analysis of the Global Burden of Disease Study 2017 – The Lancet Infectious Diseases (free)

Invited Commentary: Early childhood diarrhoea: from data to interventions (free)

Related Global Burden of Disease Report: Global Burden of Diarrhea (free)

 

8 – Antiplatelet agents for preventing pre‐eclampsia and its complications – Cochrane Library (free)

Summary: Antiplatelet agents for preventing pre-eclampsia and its complications – Cochrane Library (free)

Related Randomized Trial: Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia – New England Journal of Medicine (free study and commentaries)

 

9 – Early enteral nutrition (within 48 hours) versus delayed enteral nutrition (after 48 hours) with or without supplemental parenteral nutrition in critically ill adults – Cochrane Library (free)

Summary: Early versus delayed feeding through a tube for critically ill adults in intensive care, with or without extra nutrition into a vein – Cochrane Library (free)

 

10 – The Evidence and Controversy Between Dietary Calcium Intake and Calcium Supplementation and the Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Cohort Studies and Randomized Controlled Trials – Journal of the American College of Nutrition (free)

Related Meta-Analysis with Conflicting Results: Calcium Intake and Cardiovascular Disease Risk: An Updated Systematic Review and Meta-analysis – Annals of Internal Medicine (free)

See also: Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures (free)

 

New WHO Report to Bolster Efforts to Tackle Leading Causes of Urban Deaths

1 Nov, 2019 | 10:29h | UTC

The Power of Cities: Tackling Noncommunicable Diseases and Road Traffic Injuries – World Health Organization (free PDF)

News Release: New WHO report to bolster efforts to tackle leading causes of urban deaths – World Health Organization (free)

 

[Abstract Only] Randomized Trial: Triple Therapy Effective for the Treatment of Cystic Fibrosis

1 Nov, 2019 | 10:22h | UTC

Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele – New England Journal of Medicine (link to abstract – $ for full-text)

Editorial: Realizing the Dream of Molecularly Targeted Therapies for Cystic Fibrosis (free)

Related Research: Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentary: Three-drug combo improves lung function in most common genetic form of cystic fibrosis – UT Southwestern Medical Center (free)

 

Related Commentary on Twitter

Research: Measles Virus Infection Diminishes Preexisting Antibodies that Offer Protection from Other Pathogens

1 Nov, 2019 | 08:45h | UTC

Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens – Science (free for a limited period)

Related Research: Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles – Science Immunology (free for a limited period)

Commentaries: How measles infections can wipe away immunity to other diseases – STAT (free) AND Measles wipe immune system’s memory of other illnesses, studies find – CNN (free) AND Measles Virus May Wipe Out Immune Protection For Other Diseases – NPR (free) AND Measles vaccines protect against more than just measles. Here’s how. – National Geographic (free) AND Measles Infection Could Leave Kids Vulnerable to Other Diseases – Scientific American (free)

 

Related Commentary on Twitter

Meta-Analysis: Short- vs. Long-term Dual Antiplatelet Therapy in Secondary Prevention for Ischemic Stroke

1 Nov, 2019 | 10:24h | UTC

Short- vs. long-term dual antiplatelet therapy in secondary prevention for ischaemic stroke: a network metanalysis – European Heart Journal – Quality of Care and Clinical Outcomes (free)

Related Study: Dual Antiplatelet Therapy Should be Used for 21 Days After Minor Ischemic Stroke or High-risk Transient Ischemic Attack (link to abstract)

Related Guideline: Dual Antiplatelet Therapy for Acute High-Risk TIA and Minor Ischemic Stroke – The BMJ (free)

 

Related Commentary on Twitter

 

Global Burden, Risk Factors, and Interventions for Lower Respiratory Infections Among Children Younger than 5 Years

1 Nov, 2019 | 08:24h | UTC

Quantifying risks and interventions that have affected the burden of lower respiratory infections among children younger than 5 years: an analysis for the Global Burden of Disease Study 2017 – The Lancet Infectious Diseases (free)

Invited Commentary: Trends in the global burden of paediatric lower respiratory infections (free)

News Release: New study finds one in seven child deaths result from pneumonia, the flu, and other lower respiratory infections – Institute for Health Metrics and Evaluation (free)

Related: Global Burden of Pneumonia in Children Younger than 5 Years (free)

 

Related Commentary on Twitter

 

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