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“Intermittent fasting has salutary effects. Listen how Dr. Mark P. Mattson, co-author of a recent NEJM review on the topic, assesses the practice — and how he’s managed to skip breakfast for the past 30 years or so.”

For those interested in the subject, we suggest the reading of the recent review by Dr. Mark P. Mattson: Effects of Intermittent Fasting on Health, Aging, and Disease – New England Journal of Medicine ($)

Analysis: Smartphones, Social Media Use and Youth Mental Health

11 Feb, 2020 | 01:57h | UTC

Smartphones, social media use and youth mental health – Canadian Medical Association Journal (free)

News Release: Review of evidence finds excessive smartphone, social media use may be linked to youth mental health – Canadian Medical Association Journal (free)

Review: Cardiovascular Safety Considerations in the Treatment of Neurogenic Orthostatic Hypotension

11 Feb, 2020 | 02:01h | UTC

Cardiovascular Safety Considerations in the Treatment of Neurogenic Orthostatic Hypotension – The American Journal of Cardiology (free)

Systematic Review: Schistosomiasis-associated Pulmonary Arterial Hypertension

11 Feb, 2020 | 01:59h | UTC

Schistosomiasis-associated pulmonary arterial hypertension: a systematic review – European Respiratory Review (free)

Perspective: Step Aside CRISPR, RNA Editing is Taking Off

11 Feb, 2020 | 01:55h | UTC

Step aside CRISPR, RNA editing is taking off – Nature (free)

[Abstract Only] Another Study Suggesting One Dose of HPV Vaccine may be Effective for Prevention of Cervical Cancer

11 Feb, 2020 | 01:52h | UTC

Comparison of the long‐term impact and clinical outcomes of fewer doses and standard doses of human papillomavirus vaccine in the United States: A database study – Cancer (link to abstract – $ for full-text)

Commentaries: Single HPV vaccine dose may be effective against cervical cancer – Wiley (free) AND Expert reaction to study on single dose of HPV vaccine – Science Media Centre (free)

Perspective: Working with Patients to Improve Care

11 Feb, 2020 | 01:56h | UTC

Working with patients to improve care – Canadian Medical Association Journal (free)

Perspective – “Worried About That New Medical Study? Read This First”

11 Feb, 2020 | 01:54h | UTC

Worried About That New Medical Study? Read This First – The New York Times (free)

Deep Learning Workflow in Radiology: A Primer

11 Feb, 2020 | 01:49h | UTC

Deep learning workflow in radiology: a primer – Insights into Imaging (free)

[Abstract Only] Meta-Analysis: Increased Fluid Intake to Prevent Urinary Tract Infections

11 Feb, 2020 | 01:48h | UTC

Increased fluid intake to prevent urinary tract infections: systematic review and meta-analysis – British Journal of General Practice (link to abstract – $ for full-text)

Related Randomized Trial: Drinking More Water Prevents Recurrent Cystitis (free study and commentaries)

Clinical Controversies in Anticoagulation Monitoring and Antithrombin Supplementation for ECMO

11 Feb, 2020 | 01:44h | UTC

Clinical controversies in anticoagulation monitoring and antithrombin supplementation for ECMO – Critical Care (free)

Non-neoplastic Hepatopancreatobiliary Lesions Simulating Malignancy: Can we Differentiate?

11 Feb, 2020 | 01:50h | UTC

Non-neoplastic hepatopancreatobiliary lesions simulating malignancy: can we differentiate? – Insights into Imaging (free)

Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

9 Feb, 2020 | 20:50h | UTC

Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children – Pediatric Critical Care Medicine (free)

Executive Summary: Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children (free)

Related Commentary on Twitter

The #SurvivingSepsis Campaign has released NEW peds sepsis guidelines that recommend child-specific care for this deadly condition. Access the full guidelines published in @PedCritCareMed: https://t.co/Yjfa5kaXtb

More resources: https://t.co/R4bivYQWuA #SCCMSoMe #PedsICU pic.twitter.com/o9FslT2c6I

— SCCM (@SCCM) February 8, 2020

Mon February 10 – 10 Stories of The Day!

9 Feb, 2020 | 21:10h | UTC

1 – Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children – Pediatric Critical Care Medicine (free)

Executive Summary: Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children (free)

2 – De-implementing wisely: developing the evidence base to reduce low-value care – BMJ Quality & Safety (free) (via @brhospitalist)

3 – Gastrointestinal bleeding and the risk of colorectal cancer in anticoagulated patients with atrial fibrillation – European Heart Journal (free)

Commentary: GI Bleeding and Colorectal Cancer Risk in Anticoagulated AF Patients – American College of Cardiology (free) AND GI bleeding often mistaken as side effect of blood thinners when it could indicate cancer – Cardiovascular Business (free)

4 – Clinical Update: Diagnosis and Management of Primary Hyperparathyroidism – JAMA (free for a limited period)

5 – Potential Consequences of Changing Disease Classifications – JAMA (free for a limited period)

Author Interview: Potential Consequences of Changing Disease Classifications (free audio)

6 – Abolish the Tilt Table Test for the Workup of Syncope! – Circulation (free for a limited period)

7 – Dietary Modification and Breast Cancer Mortality: Long-Term Follow-Up of the Women’s Health Initiative Randomized Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)

8 – Clinical Cancer Advances 2020: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology – Journal of Clinical Oncology (free)

9 – Novel Coronavirus – Selected News & Perspectives / 10 February 2020

China nCoV cases continue at stable rate, concerns rise about spread in Singapore – CIDRAP (free)
Coronavirus—Unknown Source, Unrecognized Spread, and Pandemic Potential – Think Global Health (free)
WHO cautions that transmission of the new coronavirus outside of China could increase – STAT (free)
New Report on 138 Coronavirus Cases Reveals Disturbing Details – The New York Times (10 articles per month are free)
New study an eye-opener on how coronavirus is spreading and how little we know – CNN (free)
Concerns mount about coronavirus spreading in hospitals, study suggests – CNN (free) A
Demand for masks soars 100-fold, disrupting coronavirus fight: WHO – Reuters (free)
China Begins Testing an Antiviral Drug in Coronavirus Patients – The New York Times (10 articles per month are free)
Could an old malaria drug help fight the new coronavirus? – ASBMB (free)
Did pangolins spread the China coronavirus to people? – Nature (free)
Scientists question work suggesting pangolin coronavirus link – Reuters (free)
The US coronavirus travel ban could backfire. Here’s how – CNN (free)
Coronavirus: WHO chief warns against ‘trolls and conspiracy theories’ – BBC (free)

10 – Novel Coronavirus – Latest Articles / 10 February 2020

Guidelines:

Top Articles / Articles in High Impact Journals:

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China – JAMA (free) AND Commentaries: New study an eye-opener on how coronavirus is spreading and how little we know – CNN (free) AND Concerns mount about coronavirus spreading in hospitals, study suggests – CNN (free) AND New Report on 138 Coronavirus Cases Reveals Disturbing Details – The New York Times (10 articles per month are free)
Preprint: Clinical characteristics of 2019 novel coronavirus infection in China – medRxiv (free PDF) (via @greg_folkers see Tweet) (Preprint with description of 1099 patients).
Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China – JAMA (free)
Novel coronavirus infection during the 2019–2020 epidemic: preparing intensive care units—the experience in Sichuan Province, China – Intensive Care Medicine (free)
Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro – Cell Research (free) AND Commentaries: China Begins Testing an Antiviral Drug in Coronavirus Patients – The New York Times (10 articles per month are free) AND Could an old malaria drug help fight the new coronavirus? – ASBMB (free)
Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (Manis javanica) – Viruses (free) AND Commentaries: Did pangolins spread the China coronavirus to people? – Nature (free) AND Scientists question work suggesting pangolin coronavirus link – Reuters (free)
Scientists are racing to model the next moves of a coronavirus that’s still hard to predict – Science (free)
China coronavirus: labs worldwide scramble to analyse live samples – Nature (free)
Emerging Coronavirus 2019-nCoV Pneumonia – Radiology (free)

Podcast:

The 2019 Novel Coronavirus Outbreak – Update From NIAID’s Anthony Fauci, MD – JAMA (free audio)

Other Articles:

Preprints:

Clinical Update: Diagnosis and Management of Primary Hyperparathyroidism

9 Feb, 2020 | 20:45h | UTC

Diagnosis and Management of Primary Hyperparathyroidism – JAMA (free for a limited period)

Related Commentary on Twitter

JAMA Insights: the presentation and diagnostic workup of primary #hyperparathyroidism, and indications for surgical vs surveillance management. https://t.co/kUg9WeCCsc

— JAMA (@JAMA_current) February 8, 2020