Archives
Ethics in the Time of Coronavirus: Recommendations in the COVID-19 Pandemic
14 Apr, 2020 | 03:00h | UTC
Commentary on the New IDSA’s COVID-19 Treatment Guidelines
14 Apr, 2020 | 02:49h | UTCSee Original Guideline: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19
Study Validates Loss of Smell and Taste as Symptoms of Covid-19
14 Apr, 2020 | 02:57h | UTC
Face Masks Against COVID-19: An Evidence Review
14 Apr, 2020 | 02:52h | UTCFace Masks Against COVID-19: An Evidence Review – Preprints
Related Analysis: Face Masks for the Public During the Covid-19 Crisis
Review: Management of Inflammatory Bowel Disease Patients in the COVID-19 Pandemic Era
14 Apr, 2020 | 02:55h | UTCRelated: AGA Clinical Practice Update on Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: Expert Commentary – Gastroenterology AND Management of Patients with Crohn’s Disease and Ulcerative Colitis During the COVID-19 Pandemic: Results of an International Meeting – Gastroenterology
Richard Lehman’s Covid-19 Reviews
14 Apr, 2020 | 02:46h | UTCRichard Lehman’s covid-19 reviews—13 April 2020 – The BMJ Opinion
“In this weekly round-up, Richard Lehman looks at a personal selection of articles of relevance to clinicians dealing with covid-19.”
WHO Scientific Brief: BCG vaccination and COVID-19
14 Apr, 2020 | 02:47h | UTCBacille Calmette-Guérin (BCG) vaccination and COVID-19 – World Health Organization
Related Opinion: BCG Against Coronavirus: Less Hype and More Evidence, Please
“There is no evidence that the Bacille Calmette-Guérin vaccine (BCG) protects people against infection with COVID-19 virus.”
Effects of Public Health Interventions in the COVID-19 Outbreak in Wuhan, China
14 Apr, 2020 | 02:44h | UTC
2019 Novel Coronavirus (COVID-19) Pandemic: Built Environment Considerations to Reduce Transmission
14 Apr, 2020 | 02:44h | UTCCommentaries: COVID-19 and the built environment – University of California AND Scientists Reveal 2 Easy Steps To Lower Spread Of Coronavirus In Your Workplace – Study Finds
Obstetric Anesthesia During the COVID-19 Pandemic:
14 Apr, 2020 | 02:42h | UTCObstetric Anesthesia During the COVID-19 Pandemic – Anesthesia & Analgesia
Practice Changing? – Assessment of an Unplanned Extubation Bundle to Reduce Unplanned Extubations in Critically Ill Neonates, Infants, and Children
14 Apr, 2020 | 02:36h | UTC
Systematic Review: Maternal and Perinatal Outcomes with COVID‐19
14 Apr, 2020 | 02:41h | UTC
Consensus Statement: Designing Local Imaging Diagnostic Algorithms for the COVID-19 Pandemic
14 Apr, 2020 | 02:38h | UTC
AHA Statement: Management of Stable Coronary Artery Disease in Patients with Type 2 Diabetes
14 Apr, 2020 | 02:33h | UTCNews Release: People with type 2 diabetes and heart disease may benefit from newer therapies – American Heart Association
IDSA Guidelines on the Treatment and Management of Patients with COVID-19 Infection
13 Apr, 2020 | 00:27h | UTC
Related Commentary on Twitter
NEW: IDSA Guidelines on the Treatment & Management of Patients with COVID-19 Infection. These evidence-based rapid guidelines, updated in real-time, will address pressing clinical questions related to caring for patients w/ COVID-19: https://t.co/mvi9Paa8Xv #COVID19Guidelines pic.twitter.com/NKbYAbO21J
— IDSA (@IDSAInfo) April 11, 2020
Systematic Review: Treatment of Depression in Children and Adolescents
14 Apr, 2020 | 02:34h | UTCTreatment of Depression in Children and Adolescents – Agency for Healthcare Research and Quality
See also: Full Report AND Executive Summary:
Mon April 13 – 10 Stories of The Day!
13 Apr, 2020 | 00:31h | UTC
Commentaries: 40% of people with severe COVID-19 experience neurological complications – UPI AND AND Expert reaction to paper on neurological manifestations of patients hospitalised with COVID-19 in Wuhan, China – Science Media Centre
Commentaries: PulmCrit – Eleven reasons the NEJM paper on remdesivir reveals nothing AND Expert reaction to a study about compassionate use of remdesivir for patients with severe COVID-19 – Science Media Centre AND What Do the New Remdesivir Data Mean? – Science Translational Medicine
Related Observational Studies: Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia – Journal of Thrombosis and Haemostasis AND Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy – Journal of Thrombosis and Haemostasis AND Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia – Journal of Thrombosis and Haemostasis
5 – D-dimer cutoffs to predict thrombosis in COVID-19 – PulmCrit
Note: this link is not an endorsement of the algorithm.
Related Guidance: Practical guidance for the prevention of thrombosis and management of coagulopathy and disseminated intravascular coagulation of patients infected with COVID-19 – Thrombosis UK AND ISTH interim guidance on recognition and management of coagulopathy – Journal of Thrombosis and Haemostasis
7 – Mechanical Ventilators Adapted from BiPAP machines?
Modified Sleep Apnea Machines May Ease the Ventilator Crunch – Wired
Mechanical ventilators based on a simple modification of CPAP and BiPAP machines – News Medical
Turning sleep apnea machines into ventilators – Berkley Engineering
See instructions and protocols developed by Mount Sinai Health System: Repurposing bi-level ventilators for use with intubated patients while minimizing risk to health care works during insufficient supply of conventional ventilation for patients with COVID-19
We want to learn more about this interesting initiative!
8 – Studies: Obesity Increases the Risk of Complications in Patients with Covid-19
2 – Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission – Clinical Infectious Diseases AND Commentary: In New York, obesity appears to raise COVID-19 risk – CIDRAP
9 – Studies: Diabetes Increases the Risk of Complications in Patients with Covid-19
1 – Prevalence and impact of diabetes among people infected with SARS-CoV-2 – Journal of Endocrinological Investigation AND Commentary: Diabetes Could Increase Severity of COVID-19, Including Risk of ICU Admission and Death – MedicalResearch.com
2 – Evidence Reviews: Diabetes and risks from COVID-19 – CEBM University of Oxford AND Managing diabetes during the COVID-19 pandemic – CEBM University of Oxford
10 – Coronavirus Disease (COVID-19) Updates / 13 April 2020 Edition
13 April 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Compassionate Use of Remdesivir for Patients with Severe Covid-19
13 Apr, 2020 | 00:23h | UTCCompassionate Use of Remdesivir for Patients with Severe Covid-19 – New England Journal of Medicine
Commentaries: PulmCrit – Eleven reasons the NEJM paper on remdesivir reveals nothing AND Expert reaction to a study about compassionate use of remdesivir for patients with severe COVID-19 – Science Media Centre AND What Do the New Remdesivir Data Mean? – Science Translational Medicine
Study: Neurologic Manifestations Common in Hospitalized Patients with Covid-19
13 Apr, 2020 | 00:25h | UTCCommentaries: 40% of people with severe COVID-19 experience neurological complications – UPI AND AND Expert reaction to paper on neurological manifestations of patients hospitalised with COVID-19 in Wuhan, China – Science Media Centre
Possible Algorithm to Empiric Anticoagulation in COVID-19 Based on D-Dimer
13 Apr, 2020 | 00:20h | UTCD-dimer cutoffs to predict thrombosis in COVID-19 – PulmCrit
Note: this link is not an endorsement of the algorithm.
Related Guidance: Practical guidance for the prevention of thrombosis and management of coagulopathy and disseminated intravascular coagulation of patients infected with COVID-19 – Thrombosis UK AND ISTH interim guidance on recognition and management of coagulopathy – Journal of Thrombosis and Haemostasis
Incidence of Thrombotic Complications in Critically ill ICU Patients with COVID-19
13 Apr, 2020 | 00:22h | UTCRelated Observational Studies: Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia – Journal of Thrombosis and Haemostasis AND Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy – Journal of Thrombosis and Haemostasis AND Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia – Journal of Thrombosis and Haemostasis
Implementation Guide: Optimizing Medication Management during the COVID-19 Pandemic
13 Apr, 2020 | 00:18h | UTC
Related Commentary on Twitter
Task force recommendations about managing meds in post-acute and long-term care during COVID-19. https://t.co/yoU76suVYo
Summary of recommendations in thread below:
— Mike Steinman (@MikeSteinman) April 10, 2020
Studies: Obesity Increases the Risk of Complications in Patients with Covid-19
13 Apr, 2020 | 00:14h | UTC2 – Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission – Clinical Infectious Diseases AND Commentary: In New York, obesity appears to raise COVID-19 risk – CIDRAP
Mechanical Ventilators Adapted from BiPAP machines?
13 Apr, 2020 | 00:17h | UTC- Modified Sleep Apnea Machines May Ease the Ventilator Crunch – Wired
- Mechanical ventilators based on a simple modification of CPAP and BiPAP machines – News Medical
- A NYC hospital has figured out how to turn sleep apnea machines it got from Elon Musk into ventilators for coronavirus patients – Business Insider
- Turning sleep apnea machines into ventilators – Berkley Engineering
See instructions and protocols developed by Mount Sinai Health System: Repurposing bi-level ventilators for use with intubated patients while minimizing risk to health care works during insufficient supply of conventional ventilation for patients with COVID-19
We want to learn more about this interesting initiative!
Study: Antibody Tests Reveal 14% are Immune to Covid-19 in German Town
13 Apr, 2020 | 00:10h | UTC- Blood tests show 14% of people are now immune to covid-19 in one town in Germany – MIT Technology Review
- COVID antibody test in German town shows 15 percent infection rate – Spectator
- Expert reaction to unpublished preliminary findings looking at the presence of antibodies to SARS-CoV-2 virus in residents of Gangelt, in Germany – Science Media Centre
The original report can be found here (in German)