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Modeling study: Risk of resurgence up to 97% if all restrictions are lifted after 14 days with no new cases

22 Jul, 2020 | 02:21h | UTC

Reconstruction of the full transmission dynamics of COVID-19 in Wuhan – Nature

Commentary: Epidemiology: Covert infections may have contributed to the rapid spread of COVID-19 – Nature Asia

 

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

22 Jul, 2020 | 02:22h | UTC

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls – Nature

Commentaries: New Data on T Cells and the Coronavirus – Science Translational Medicine AND Scientists uncover SARS-CoV-2-specific T cell immunity in recovered COVID-19 and SARS patients – Duke-NUS Medical School AND Expert reaction to study looking at SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS and uninfected controls from data from Singapore – Science Media Centre

 

Universal COVID-19 testing may reduce spread in long-term care facilities

22 Jul, 2020 | 02:18h | UTC

Outcomes of Universal COVID-19 Testing Following Detection of Incident Cases in 11 Long-term Care Facilities – JAMA Internal Medicine

Commentaries: Universal COVID-19 testing in nursing homes may limit transmission – UPI AND Report Underscores Importance Of Universal Covid-19 Testing In Nursing Homes – MedicalResearch.com

 

Assessing the impact of coordinated COVID-19 exit strategies across Europe

22 Jul, 2020 | 02:20h | UTC

Assessing the impact of coordinated COVID-19 exit strategies across Europe – Science

Commentary: Coordinated exit strategies crucial to avoid virus second-wave in Europe – University of Southampton

 

Systematic review: induction of labor at or beyond 37 weeks’ gestation

22 Jul, 2020 | 02:16h | UTC

Induction of labour at or beyond 37 weeks’ gestation – Cochrane Library

Summary: Induction of labour in women with normal pregnancies at or beyond 37 weeks – Cochrane Library

 

Medication management in frail older people: Consensus principles for clinical practice, research, and education

22 Jul, 2020 | 02:17h | UTC

Medication Management in Frail Older People: Consensus Principles for Clinical Practice, Research, and Education – Journal of Post-Acute and Long-Term Care Medicine

News Release: Monash University researchers develop new international consensus principles for medicines management in frail older people

 

[Abstract Only] Meta-analysis: association of delirium with long-term cognitive decline

22 Jul, 2020 | 02:12h | UTC

Association of Delirium With Long-term Cognitive Decline: A Meta-analysis – JAMA Neurology

Commentary: Delirium linked to long-term cognitive decline – News Medical

 

[Abstract Only] Randomized trial: effects of 4- and 6-h time-restricted feeding on weight and cardiometabolic health

22 Jul, 2020 | 02:09h | UTC

Effects of 4- and 6-h Time-Restricted Feeding on Weight and Cardiometabolic Health: A Randomized Controlled Trial in Adults with Obesity – Cell Metabolism

Commentary: How long should you fast for weight loss? – University of Illinois at Chicago

 

Canadian Cardiovascular Society position statement on pulmonary hypertension

22 Jul, 2020 | 02:14h | UTC

Canadian Cardiovascular Society/Canadian Thoracic Society Position Statement on Pulmonary Hypertension – Canadian Journal of Cardiology

 

[Abstract Only] Randomized trial: Carfilzomib, dexamethasone, and daratumumab vs. carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma

22 Jul, 2020 | 02:11h | UTC

Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): results from a randomised, multicentre, open-label, phase 3 study – The Lancet

 

AHA scientific statement: Importance of housing and cardiovascular health and well-being

22 Jul, 2020 | 02:08h | UTC

Importance of Housing and Cardiovascular Health and Well-Being: A Scientific Statement From the American Heart Association – Circulation: Cardiovascular Quality and Outcomes

News Release: Housing conditions affect cardiovascular health risks – American Heart Association

Top Things to Know: Importance of Housing and Cardiovascular Health and Well-Being

 

Wed July 22 – 10 Stories of The Day!

22 Jul, 2020 | 02:38h | UTC

 

1 – The RECOVERY Platform – New England Journal of Medicine

 

2 – Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19 – New England Journal of Medicine

 

3 – Seroprevalence of Antibodies to SARS-CoV-2 in 10 Sites in the United States, March 23-May 12, 2020 – JAMA Internal Medicine

Editorial: Serosurveillance and the COVID-19 Epidemic in the US: Undetected, Uncertain, and Out of Control – JAMA

Commentaries: Actual Covid-19 case count could be 6 to 24 times higher than official estimates, CDC study shows – STAT AND Coronavirus Infections Much Higher Than Reported Cases in Parts of U.S., Study Shows – The New York times

 

4 – Community prevalence of SARS-CoV-2 virus in England during May 2020: REACT study – medRxiv

Commentary: Expert reaction to preprint (not a published paper) from the REACT study on community prevalence of SARS-CoV-2 – Science Media Centre

 

5 – Impact of delays on effectiveness of contact tracing strategies for COVID-19: a modelling study – The Lancet Public Health

Commentaries: Quick testing is needed for coronavirus contact tracing to be most effective, research finds – CNN AND Speed of testing is most critical factor in the success of contact tracing strategies to slow COVID-19 transmission – The Lancet AND Expert reaction to paper looking at COVID-19 contact tracing strategies and speed of testing – Science Media Centre AND Can digital contact tracing make up for lost time? – The Lancet Public Health

 

6 – Care of the pregnant woman with coronavirus disease 2019 in labor and delivery: anesthesia, emergency cesarean delivery, differential diagnosis in the acutely ill parturient, care of the newborn, and protection of the healthcare personnel – American Journal of Obstetrics & Gynecology

 

7 – Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study – medRxiv

 

8 – Clinical Manifestations and Outcomes of Critically Ill Children and Adolescents with COVID-19 in New York City – The Journal of Pediatrics

 

9 – SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls – Nature

Commentaries: New Data on T Cells and the Coronavirus – Science Translational Medicine AND Scientists uncover SARS-CoV-2-specific T cell immunity in recovered COVID-19 and SARS patients – Duke-NUS Medical School AND Expert reaction to study looking at SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS and uninfected controls from data from Singapore – Science Media Centre

 

10 –COVID-19 Updates / 22 July 2020 Edition

22 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

 

Phase 2 randomized trial: immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults

21 Jul, 2020 | 09:29h | UTC

Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial – The Lancet

Commentaries: China’s Ad5 vectored COVID-19 vaccine safe and induces immune response – News Medical AND CanSino COVID-19 vaccine generates immune response in 90% of patients – UPI

 

Related Commentary on Twitter

https://twitter.com/TheLancet/status/1285209554775617536

 

Editorial: encouraging results from phase 1/2 COVID-19 vaccine trials

21 Jul, 2020 | 09:35h | UTC

Encouraging results from phase 1/2 COVID-19 vaccine trials – The Lancet

Podcast: The Lancet Editor-in-Chief Richard Horton explains the current status of the Oxford and China COVID-19 vaccines

Commentaries: Promising early findings for 2 more COVID-19 vaccines – CIDRAP AND Expert reaction to two vaccine candidate studies: a phase 1/2 trial of the University of Oxford’s ChAdOx1 vaccine candidate; and a phase 2 trial of China’s Ad5-vectored COVID-19 vaccine candidate – Science Media Centre

 

[Press release-based medicine…] Synairgen announces positive results from trial of SNG001 in hospitalized COVID-19 patients

21 Jul, 2020 | 09:27h | UTC

Synairgen announces positive results from trial of SNG001 in hospitalised COVID-19 patients

Commentaries: New Treatment for Covid-19 Shows Promise, but Scientists Urge Caution – The New York Times AND Expert reaction to announcement by Synairgen that their drug SNG001 has had positive results in initial trials on COVID-19 patients – Science Media Centre AND Trial of Covid-19 drug given via inhaler ‘very promising’, say scientists – The Guardian

 

Phase 1/2 randomized trial: safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2

21 Jul, 2020 | 09:33h | UTC

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial – The Lancet

Commentaries: New study reveals Oxford coronavirus vaccine produces strong immune response – University of Oxford AND Oxford’s Covid-19 vaccine appears safe and induces immune response, early results suggest, but more research is needed – CNN AND Early Oxford-AstraZeneca Coronavirus Vaccine Data ‘Encouraging,’ Scientists Say – NPR

 

Related Commentary on Twitter

 

Survivorship after COVID-19 ICU stay

21 Jul, 2020 | 09:23h | UTC

Survivorship after COVID-19 ICU stay – Nature Reviews

 

[Preprint] Covid-19: Six clusters of symptoms could be used as a clinical prediction tool

21 Jul, 2020 | 09:25h | UTC

Symptom clusters in Covid19: A potential clinical prediction tool from the COVID Symptom study app – medRxiv

Commentaries: Covid-19: Study reveals six clusters of symptoms that could be used as a clinical prediction tool – The BMJ AND Six distinct ‘types’ of COVID-19 identified – King’s College London AND Coronavirus symptoms fall into six different groupings, study finds – The Guardian

 

Modeling study: impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis

21 Jul, 2020 | 09:19h | UTC

The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study – The Lancet Oncology

 

Related Commentary on Twitter

 

Thrombosis in hospitalized patients with COVID-19 in a New York City health system

21 Jul, 2020 | 09:21h | UTC

Thrombosis in Hospitalized Patients With COVID-19 in a New York City Health System – JAMA

 

[Abstract Only] Randomized trial: Dexmedetomidine does not decrease postoperative atrial arrhythmias or delirium in patients recovering from cardiac surgery

21 Jul, 2020 | 09:16h | UTC

Dexmedetomidine for reduction of atrial fibrillation and delirium after cardiac surgery (DECADE): a randomised placebo-controlled trial – The Lancet

 

Related Commentary on Twitter

https://twitter.com/NydahlPeter/status/1285199896958644231

 

Study: Increased incidence of ketoacidosis in children and adolescents with newly diagnosed Type 1 Diabetes during the COVID-19 pandemic

21 Jul, 2020 | 09:22h | UTC

Ketoacidosis in Children and Adolescents With Newly Diagnosed Type 1 Diabetes During the COVID-19 Pandemic in Germany – JAMA

 

How (not) to write about global health

21 Jul, 2020 | 09:05h | UTC

How (not) to write about global health – The BMJ Global Health

 

Related Commentary on Twitter

 

Guideline: Diagnosing acute aortic syndrome

21 Jul, 2020 | 09:18h | UTC

Diagnosing acute aortic syndrome: a Canadian clinical practice guideline – Canadian Medical Association Journal

Commentary: New guideline can help clinicians identify hard-to-diagnose acute aortic syndrome – News Medical

 

Podcast on acute kidney injury: myths & musings

21 Jul, 2020 | 08:59h | UTC

#226 Kidney Boy on Acute Kidney Injury: Myths & Musings – The Curbsiders Internal Medicine Podcast

 

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