Archives
Randomized trial: Cannula with long and narrow tubing noninferior to short binasal prongs for noninvasive ventilation in preterm infants
15 Jan, 2021 | 08:15h | UTCCannula With Long and Narrow Tubing vs Short Binasal Prongs for Noninvasive Ventilation in Preterm Infants: Noninferiority Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)
Commentary: Israeli study finds effective, less invasive way to treat preterm babies – The Jerusalem Post
Commentary on Twitter
New RCT on @JAMAPediatrics shows cannulas with long and narrow tubing (CLNT) to be noninferior to short binasal prongs and masks (SPM) in providing NIPPV for preterm infants, while causing significantly less nasal trauma: https://t.co/zdW6zcM7NY #neoEBM #ebneoalerts pic.twitter.com/Q9qBQLxdwT
— Evidence-Based Neo (@EBNEO) November 15, 2020
Randomized trial: Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma
15 Jan, 2021 | 08:12h | UTCOnce-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma (BOSTON): a randomised, open-label, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Triplet therapy slows refractory multiple myeloma – MedicalXpress
Systematic review: Prostatic arterial embolization for men with symptomatic benign prostatic hyperplasia provides similar short term (up to 12 months) improvement in urologic symptom scores and quality of life, but with an increase in re-treatment rates
15 Jan, 2021 | 08:11h | UTC
Systematic review: Adding abiraterone acetate to androgen deprivation therapy for the treatment of metastatic hormone-sensitive prostate cancer
15 Jan, 2021 | 08:10h | UTC
CoronaVac study in Brazil: Is the vaccine 50%, 78%, or 100% effective?
14 Jan, 2021 | 02:11h | UTCThird time’s the charm? Brazil scales back efficacy claims for COVID-19 vaccine from China – Science
See also: CoronaVac’s Overall Efficacy in Brazil Measured at 50.4% – Bloomberg
Systematic review: Oral hygiene care with chlorhexidine mouthwash or gel in critically ill patients probably reduces the incidence of developing ventilator-associated pneumonia
15 Jan, 2021 | 08:09h | UTC
Meta-analysis: Saliva vs. nasopharyngeal swabs equally sensitive for Covid-19 diagnosis
14 Jan, 2021 | 02:13h | UTCCommentary: Saliva, Nasopharyngeal Samples Equally Sensitive for SARS-CoV-2 – Physician’s Weekly
Commentary on Twitter
https://twitter.com/EricTopol/status/1348758183846703104
A guide to vaccinology: from basic principles to new developments
14 Jan, 2021 | 02:09h | UTCA guide to vaccinology: from basic principles to new developments – Nature Reviews Immunology
Pragmatic Recommendations for the Management of COVID-19 in Low- and Middle-Income Countries
14 Jan, 2021 | 02:04h | UTC- Editorial: Recommendations for the Management of COVID-19 in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for the Management of Acute Respiratory Failure and Mechanical Ventilation in Patients with COVID-19 in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for the Management of Anticoagulation and Venous Thrombotic Disease for Hospitalized Patients with COVID-19 in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for Identification and Triage of Patients with COVID-19 Disease in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for Tracheostomy, Discharge, and Rehabilitation Measures in Hospitalized Patients Recovering From Severe COVID-19 in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for the Prevention and Treatment of Acute Kidney Injury in Patients with COVID-19 in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for Infection Prevention and Control Practices for Healthcare Facilities in Low- and Middle-Income Countries during the COVID-19 Pandemic – Journal of Tropical Medicine and Hygiene
How COVID unlocked the power of RNA vaccines
14 Jan, 2021 | 02:09h | UTCHow COVID unlocked the power of RNA vaccines – Nature
Commentary: RNA Vaccines: A Suitable Platform for Tackling Emerging Pandemics? – Frontiers in Immunology
Three studies highlight low COVID risk of in-person school
14 Jan, 2021 | 02:06h | UTCThree studies highlight low COVID risk of in-person school – CIDRAP
Study 1: Open Schools, Covid-19, and Child and Teacher Morbidity in Sweden – New England Journal of Medicine
Study 2: Incidence and Secondary Transmission of SARS-CoV-2 Infections in Schools – Pediatrics
No ICU beds? Expect double the number of Covid-19 deaths
14 Jan, 2021 | 02:05h | UTCNo ICU beds? Expect double the number of Covid-19 deaths. – Vox
Study estimates 50% of new SARS-CoV-2 infections have originated from exposure to asymptomatic or pre-symptomatic individuals
14 Jan, 2021 | 02:08h | UTCSARS-CoV-2 Transmission From People Without COVID-19 Symptoms – JAMA Network Open
Commentary: At least 50% of COVID-19 cases spread from people without symptoms, a new study found – Business Insider AND More than half of Covid-19 infections acquired from asymptomatic carriers – MedicalResearch
Commentary on Twitter
https://twitter.com/TennantRuth/status/1348208811039985665
Perspective: For people with OCD — and fearful of germs — the pandemic is upending years of therapy
14 Jan, 2021 | 02:00h | UTCFor people with OCD — and fearful of germs — the pandemic is upending years of therapy – STAT
Preparing previously COVID-19-positive patients for elective surgery: A framework for preoperative evaluation
14 Jan, 2021 | 02:02h | UTC
Study: Despite recommendations, less than 2 percent of patients with treatment-resistant hypertension were tested for primary aldosteronism in a large U.S. cohort
14 Jan, 2021 | 01:55h | UTCTesting for Primary Aldosteronism and Mineralocorticoid Receptor Antagonist Use Among U.S. Veterans: A Retrospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Primary Aldosteronism Testing Rare in Treatment-Resistant HTN – HealthDay AND Primary Aldosteronism Testing Rare for Patients with Resistant Hypertension – NEJM Journal Watch
Commentary from the author on Twitter (thread – click for more)
Our new study is out in @AnnalsofIM w/@BhallaResearch @thebyrdlab @johnleppert! 👇https://t.co/UCrAD4ed0w
We asked: Are patients w/treatment resistant HTN being appropriately tested for primary aldosteronism (PA) & managed w/mineralocorticoid receptor antagonists (MRAs)? 1/ pic.twitter.com/jO4cqA37sD
— Jordy Cohen, MD, MSCE (@jordy_bc) December 28, 2020
Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin
14 Jan, 2021 | 01:57h | UTCEditorial: Evolving Issues in the Use of Antibiotics for the Treatment of Uncomplicated Appendicitis
Commentary: More Support for Single-Drug Antibiotics for Uncomplicated Appendicitis – Physician’s Weekly
Commentary on Twitter
In this RCT comparing 7d oral moxifloxacin vs 2d IV ertapenam 5d oral levofloxacin metronidazole for adults w uncomplicated #appendicitis, Tx success was >65% for both, but oral #antibiotics did not meet noninferiority criteria vs IV PO https://t.co/SwcopsGZTm #VisualAbstract
— JAMA (@JAMA_current) January 12, 2021
Imaging of Pulmonary Hypertension in Adults: A Position Paper from the Fleischner Society
14 Jan, 2021 | 01:51h | UTC
ACR Consensus Statement: Use of intravenous gadolinium-based contrast media in patients with kidney disease
14 Jan, 2021 | 01:52h | UTC
Commentary on Twitter
The potential harms of delaying or withholding group II GBCM for an MRI likely outweigh the risks of NSF in patients with acute kidney injury or moderate-to-severe loss of kidney function. This study in @radiology_rsna explains why. https://t.co/yZV38mpuLN #AbdRad pic.twitter.com/i46pK2FyB7
— RSNA (@RSNA) December 11, 2020
Systematic review into city interventions to address obesity
14 Jan, 2021 | 01:50h | UTCSystematic review into city interventions to address obesity – EClinicalMedicine
Global, regional, and national dengue burden from 1990 to 2017: A systematic analysis based on the global burden of disease study 2017
14 Jan, 2021 | 01:48h | UTC
Systematic review: Does behavioral support help people to stop smoking?
14 Jan, 2021 | 01:46h | UTCSummary: Does behavioural support help people to stop smoking? – Cochrane Library
Guideline: Malignant hyperthermia 2020
14 Jan, 2021 | 01:45h | UTCMalignant hyperthermia 2020: Guideline from the Association of Anaesthetists – Anaesthesia
Guideline: Update on perioperative hypersensitivity reactions
14 Jan, 2021 | 01:44h | UTCUpdate on perioperative hypersensitivity reactions: joint document of the Brazilian Society of Anesthesiology (SBA) and Brazilian Association of Allergy and Immunology (ASBAI) – Brazilian Journal of Anesthesiology
Part I: post-crisis guidelines and treatment
Part II: etiology and diagnosis
ATS Research Statement: Informing healthcare decisions with observational research assessing causal effect
14 Jan, 2021 | 01:43h | UTC