Archives
Review: Nosocomial infection in the ICU setting
9 Feb, 2021 | 01:05h | UTCNosocomial Infection – Critical Care Medicine
Canadians Win Again – Syncope Score Systematic Review
9 Feb, 2021 | 01:03h | UTCCanadians Win Again – Syncope Score Systematic Review – Journal Feed
See calculator: Canadian Syncope Risk Score – MdCalc
RCT: Dobutamine-sparing vs. dobutamine-to-all strategy in cardiac surgery
9 Feb, 2021 | 00:57h | UTC
RCT: Total Body Irradiation vs. Chemotherapy Conditioning in Childhood ALL
9 Feb, 2021 | 00:39h | UTCCommentary: TBI Beats Chemoconditioning for ALL Transplants in Children – Medscape (free registration required)
Commentary on Twitter
Total body irradiation or chemotherapy conditioning in childhood acute lymphoblastic leukemia (ALL) — outcomes suggest there's still a role for TBI https://t.co/ICTC0iEGN8 #leusm #pedonc #pedcsm #JCO pic.twitter.com/xARMBlSeni
— Journal of Clinical Oncology (@JCO_ASCO) December 26, 2020
FDA Drug Safety Communication: Initial safety trial results find Tofacitinib, used for arthritis and ulcerative colitis, may increase the risk of serious heart-related problems and cancer
9 Feb, 2021 | 01:00h | UTCCommentary: Arthritis, Colitis Drug Tied to Heart-Related Problems and Cancer – NEJM Journal Watch
Variant-proof vaccines — invest now for the next pandemic
9 Feb, 2021 | 01:39h | UTCVariant-proof vaccines — invest now for the next pandemic – Nature
Thrombosis and COVID-19: Controversies and (Tentative) Conclusions
9 Feb, 2021 | 01:41h | UTCThrombosis and COVID-19: Controversies and (Tentative) Conclusions – Clinical Infectious Diseases
Commentary on Twitter
https://twitter.com/JohnRossMD/status/1357992429824081921
Small RCT: Peginterferon lambda increases viral clearance in outpatients with COVID-19
9 Feb, 2021 | 01:36h | UTC
Coronavirus vaccine strategy needs rethink after resistant variants emerge, say scientists
9 Feb, 2021 | 01:38h | UTCRelated: South Africa halts AstraZeneca vaccine rollout over new variant – BBC AND ‘What other variants might be out there?’ An expert on viral evolution on what’s happening with coronavirus mutations – STAT AND Covid-19: Oxford vaccine offers less protection against South Africa variant (study and commentaries) AND South Africa suspends use of AstraZeneca’s COVID-19 vaccine after it fails to clearly stop virus variant – Science
Mitigating inequities and saving lives with ICU triage during the COVID-19 pandemic
9 Feb, 2021 | 01:29h | UTC
Does taking Vitamin D prevent or treat COVID-19?
9 Feb, 2021 | 01:20h | UTCDoes Taking Vitamin D Prevent or Treat COVID-19? – HIV and ID Observations
ARDS: Contemporary management and novel approaches during COVID-19
9 Feb, 2021 | 01:31h | UTC
Commentary on Twitter
Review Article: Acute Respiratory Distress Syndrome #ARDS: Contemporary Management and Novel Approaches during #COVID19 https://t.co/Hbsuejegos pic.twitter.com/9rOyZmOWpA
— Anesthesiology (@_Anesthesiology) February 5, 2021
Perspective: Pregnancy, postpartum care, and COVID-19 vaccination in 2021
9 Feb, 2021 | 01:16h | UTCPregnancy, Postpartum Care, and COVID-19 Vaccination in 2021 – JAMA
Perspective: COVID-19 vaccination in pregnant and lactating women
9 Feb, 2021 | 01:18h | UTCCOVID-19 Vaccination in Pregnant and Lactating Women – JAMA
Related: Fauci says ‘no red flags’ seen in 10,000 pregnant women who’ve received Covid shots so far – CNBC
Patients with lymphoma receiving B-Cell–depleting therapies may be at greater risk for persistent COVID-19 infection
9 Feb, 2021 | 01:14h | UTCRelated: Patients on Active Chemotherapy May Not Be at Increased Risk for COVID-19 Infection – The ASCO Post
See also: Anti-CD20 Drugs Tied to Severe COVID in Cancer Patients — Plus: Active chemo treatment may not be a COVID risk factor – MedPage Today (free registration required)
Telehealth’s critics have it right: The industry must evolve
9 Feb, 2021 | 00:46h | UTCTelehealth’s critics have it right: The industry must evolve – STAT
M-A: Effects of whole grain intake, compared with refined grain, on appetite and energy intake
9 Feb, 2021 | 00:50h | UTC
Commentary on Twitter
Effects of Whole Grain Intake, Compared with Refined Grain, on Appetite and Energy Intake: A Systematic Review and Meta-Analysis
"Whole grains modestly but significantly reduced
hunger…"https://t.co/wS1Vql4KHi@nutritionorg @jnutritionorg pic.twitter.com/5UWa28wkPW— Lukas Schwingshackl (@LSchwingshackl) February 8, 2021
Implantable defibrillators may be inhibited by phones containing magnets
9 Feb, 2021 | 00:55h | UTCLife Saving Therapy Inhibition by Phones Containing Magnets – Heart Rhythm
Commentaries: Got an implantable defibrillator or a pacemaker? Keep your iPhone 12 in your trouser pocket, not your shirt – The Conversation AND IPhone12 will stop your implantable defibrillator – MedicalXpress
Commentary on Twitter
Well that’s seems important – iPhone 12’s MagSafe magnet can disable an ICD. Got to put it right up to the icd: no left chest pockets for you iPhone 12https://t.co/GrF5KRQNjW
— Eric Widera, MD (@EWidera) February 2, 2021
RCT: In patients with cirrhosis treated with TIPS, prophylactic rifaximin reduced the risk for Hepatic Encephalopathy
7 Feb, 2021 | 21:10h | UTCThe Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Rifaximin prevents overt hepatic encephalopathy after TIPS – HealthDay
Commentary on Twitter
New findings published in @AnnalsofIM:
In patients with #cirrhosis treated with TIPS, rifaximin was well tolerated and reduced the risk for overt HE. #Rifaximin should therefore be considered for prophylaxis of post-TIPS HE https://t.co/d2p9dfcx3s. pic.twitter.com/M7zwmUxQA3
— Annals of Int Med (@AnnalsofIM) February 2, 2021
Intraoperative imaging technology to maximize extent of resection for glioma: a network meta‐analysis
8 Feb, 2021 | 20:11h | UTC
RCT: Day-of-surgery video calls and phone calls increase patient satisfaction with outpatient surgery experience
9 Feb, 2021 | 00:44h | UTCCommentary: Day-of-Surgery Post-op Talks with Patients Worth the Effort – OrthoBuzz
RCT: Posaconazole noninferior to voriconazole for primary treatment of invasive aspergillosis
7 Feb, 2021 | 21:00h | UTCPosaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
RCT: Enteral lipid supplement reduces the risk of severe retinopathy of prematurity
7 Feb, 2021 | 21:04h | UTCCommentary: Halved risk for severe retinal disease in extremely premature infants – University of Gothenburg
Commentary on Twitter
A new study at #jamapeds reports that enteral fatty acid supplementation with AA and DHA lowers the risk of retinopathy of prematurity among extremely preterm infants. https://t.co/skN41O2YX4 pic.twitter.com/c9bv3V6wbn
— JAMA Pediatrics (@JAMAPediatrics) February 4, 2021
SR/MA: Up to a third of patients may discontinue thyroid hormone replacement and remain euthyroid
7 Feb, 2021 | 21:02h | UTCClinical Outcomes After Discontinuation of Thyroid Hormone Replacement: A Systematic Review and Meta-Analysis – Thyroid (link to abstract – $ for full-text)
Commentary: A Third Discontinuing Levothyroxine Have Normal Thyroid Levels – Medscape (free registration required)
Commentaries on Twitter
Hard to believe that simply treating hypothyroidism may fit into “Things We Do For No Reason.”
But >1/3 of people on thyroid replacement stay euthyroid after stopping meds.
See article for results, predictors of euthyroidism, & de-escalation strategies.https://t.co/i1f04FnbPk pic.twitter.com/fGLAbjNo5B
— David A. Cohen (@DavidACohen_MD) January 21, 2021
(thread – click for more)
#endocation #endotwitter #endotips #endorules
Hypothyroidism🧠: Third of Patients Treated for
Hypothyroidism May Not Require Thyroid Hormones❗️https://t.co/iAZcwFB5Ul✅Hypothyroidism: 5% of population, age dependent
✅NHANES: 6.4% reported use of levothyroxine (LT4)1/
— Fady Hannah-Shmouni, MD FRCPC (@DrShmouni) January 14, 2021
Guideline synopsis: Management of immunotherapy-related toxicities in patients treated with immune checkpoint inhibitor therapy
7 Feb, 2021 | 20:55h | UTCManagement of Immunotherapy-Related Toxicities in Patients Treated With Immune Checkpoint Inhibitor Therapy – JAMA (free for a limited period)
Audio Clinical Review: Management of Immunotherapy-Related Toxicities
Original guideline and other resources: NCCN Guidelines Insights: Management of Immunotherapy-Related Toxicities