Archives
RCT: Five oral analgesics (including opioids) are equally effective for the treatment of acute musculoskeletal extremity pain in the emergency department
21 Feb, 2021 | 21:39h | UTCA Randomized Trial Comparing the Efficacy of Five Oral Analgesics for Treatment of Acute Musculoskeletal Extremity Pain in the Emergency Department – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Hot off the Press: A Randomized Trial Comparing the Efficacy of
Five Oral Analgesics for Treatment of Acute
Musculoskeletal Extremity Pain in the Emergency
Department https://t.co/qfUNn2TgZM @benjaminbwf pic.twitter.com/BzVM3W5F0L— AnnalsofEM (@AnnalsofEM) December 30, 2020
Clinical practice guidelines for BRCA1 and BRCA2 genetic testing
21 Feb, 2021 | 21:43h | UTCClinical practice guidelines for BRCA1 and BRCA2 genetic testing – European Journal of Cancer
Commentary on Twitter
BRCA1 and BRCA2 genetic testing- Clinical practice guidelineshttps://t.co/bpdXf70PnW pic.twitter.com/i6O0br35ap
— K Pavithran (@drkpavithran) February 15, 2021
Opinion – Is it time to delay second doses of coronavirus vaccines?
21 Feb, 2021 | 22:39h | UTCIs it time to delay second doses of coronavirus vaccines? – CNN
3-month interval between first and second dose of Oxford COVID-19 vaccine results in higher vaccine efficacy than 6-week interval
21 Feb, 2021 | 22:42h | UTC
Opinion – Delayed second dose of the BNT162b2 vaccine: innovation or misguided conjecture?
21 Feb, 2021 | 22:38h | UTCDelayed second dose of the BNT162b2 vaccine: innovation or misguided conjecture? – The Lancet
Study: One Pfizer/BioNTech shot gives 85% Covid protection
21 Feb, 2021 | 22:41h | UTCOne Pfizer/BioNTech shot gives 85% Covid protection – study – The Guardian
Original study: Early rate reductions of SARS-CoV-2 infection and COVID-19 in BNT162b2 vaccine recipients – The Lancet
Commentary on Twitter
NEW Correspondence reports early findings from study of #Pfizer #vaccine in health-care workers in Israel, suggesting early reductions in #COVID19 infection and symptomatic rates following first dose. Read https://t.co/ONU8bS3Iwo pic.twitter.com/BDDvA7Juyb
— The Lancet (@TheLancet) February 19, 2021
Pfizer vaccine doesn’t need ultra-cold storage after all, company says
21 Feb, 2021 | 22:37h | UTCPfizer vaccine doesn’t need ultra-cold storage after all, company says – ARS Technica
News release: PFIZER AND BIONTECH SUBMIT COVID-19 VACCINE STABILITY DATA AT STANDARD FREEZER TEMPERATURE TO THE U.S. FDA
Commentary on Twitter
🔥Pfizer BioNTech announced submission of new data to the U.S. FDA demonstrating the stability of their COVID-19 vaccine when stored at -25°C to -15°C (-13°F to 5°F), temperatures more commonly found in pharmaceutical freezers and refrigerators🔥https://t.co/egFsSe4oBB
— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) February 19, 2021
Twelve criteria for the development and use of COVID-19 vaccine passports
21 Feb, 2021 | 22:36h | UTCTwelve criteria for the development and use of COVID-19 vaccine passports – The Royal Society
Commentaries: Vaccine passports can work, but face 12 challenges – University of Oxford AND UK scientists highlight 12 criteria for Covid vaccine passports – The Guardian
See also: What place should COVID-19 vaccine passports have in society? – Ada Lovelace Institute AND WHO looks at possible ‘e-vaccination certificates’ for travel – Reuters
Intensive care management of patients with COVID-19: a practical approach
21 Feb, 2021 | 22:34h | UTCRelated Guideline: Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update AND Infographic
Coronapod: our future with an ever-present coronavirus
21 Feb, 2021 | 22:32h | UTCCoronapod: our future with an ever-present coronavirus – Nature
Long Covid: Sequelae in adults at 6 Months after COVID-19 infection
21 Feb, 2021 | 22:13h | UTCSequelae in Adults at 6 Months After COVID-19 Infection – JAMA Network Open
Commentaries: Almost a third of people with ‘mild’ COVID-19 still battle symptoms months later, study finds – CNN AND Nearly One Third of Covid-19 Survivors Have Symptoms, Some Up To 9 Months Later, New Study Finds – Forbes
Commentary on Twitter
Long COVID:
~1/3 of COVID-19 pts had lingering symptoms of a median of 6 mths after infection onset.Among pts whose infections ranged from asymptomatic to severe, 2 problems — fatigue & loss of smell/taste persisted most frequently.https://t.co/xoaWwskPnP
— Christopher Lee (@chriskc_Lee) February 20, 2021
Multi-parametric CT offers earlier detection for common liver disease
21 Feb, 2021 | 21:37h | UTCMulti-Parametric CT Offers Earlier Detection for Common Liver Disease – Clinical Imaging
Original study: Utility of Multiparametric CT for Identification of High-Risk NAFLD – American Journal of Roentgenology (link to abstract – $ for full-text)
Initial management of noncastrate advanced, recurrent, or metastatic prostate cancer: ASCO guideline update
21 Feb, 2021 | 21:47h | UTC
SR: Multisystem inflammatory syndrome in children related to COVID-19
21 Feb, 2021 | 22:11h | UTC
Commentary on Twitter (thread – click for more)
Very proud to present our systematic review on the hyperinflammatory syndrome associated with SARS-CoV-2 in children #PIMS_TS #MISC, as published today in @EurJPediatrics.
We analyzed and summarized over 950 cases from more than 60 records. https://t.co/jO3te1KUIE
(1/n) pic.twitter.com/6BwEw7qFzi
— Levi Hoste (@LeviHoste) February 18, 2021
Meta-analysis: Effect of food variety on intake of a meal
21 Feb, 2021 | 21:33h | UTC
Current use of inotropes in circulatory shock
21 Feb, 2021 | 21:34h | UTCCurrent use of inotropes in circulatory shock – Annals of Intensive Care
Impact of patient-reported symptom information on lumbar spine MRI Interpretation
21 Feb, 2021 | 21:36h | UTCCommentaries: Talking to Patients About Pain Can Improve Lumbar Spine MRI Interpretation – Diagnostic Imaging AND Impact of patient-reported symptom information on lumbar spine MRI Interpretation – American Roentgen Ray Society
Commentary on Twitter
In lumbar spine MRI, presumptive pain generators diagnosed using symptom information from electronic questionnaires showed almost perfect agreement with pain generators diagnosed using symptom information from direct patient interviews.https://t.co/jDzPUrWcrw pic.twitter.com/Q8QmKlsnd1
— AJR (@AJR_Radiology) January 21, 2021
M-A: Intra-articular saline injection is as effective as corticosteroids, platelet-rich plasma, and hyaluronic acid for hip osteoarthritis pain
19 Feb, 2021 | 02:35h | UTC
Commentary on Twitter
Anyone else buying shares in saline? 👀
Intra-articular saline as effective as corticosteroids, PRP and hyaluronic acid for hip OA pain: a systematic review and network meta-analysis #NoSilverBullet #Paywallhttps://t.co/B6tutNJVDD pic.twitter.com/f75ExkZ2A6
— British Journal of Sports Medicine (BJSM) (@BJSM_BMJ) August 27, 2020
Study: In intensively treated hypertensive patients, a diastolic blood pressure of less than 60 mm Hg was associated with increased risk of cardiovascular events
19 Feb, 2021 | 02:37h | UTCCommentary: Treated Diastolic Blood Pressure: How Low Is Too Low? – NEJM Journal Watch
Commentary on Twitter
Cohort study showed on-treatment diastolic BP <60 was associated with increased risk of adverse outcomes; on-treatment diastolic BP of 70-80 was associated with lowest adverse outcome risk in patients with on-treatment systolic BP <130 mmHg. @MayoClinic https://t.co/0wOfqpMcIH
— JAMA Network Open (@JAMANetworkOpen) February 17, 2021
Guide to statistics and methods: Immortal time bias in observational studies
19 Feb, 2021 | 02:19h | UTCImmortal Time Bias in Observational Studies – JAMA (free for a limited period)
Commentary on Twitter
https://twitter.com/lucasmorin_eolc/status/1361966403985825792
The Lancet Commission on Global Eye Health: Vision Beyond 2020
19 Feb, 2021 | 02:38h | UTCGlobal Eye Health: vision beyond 2020 – The Lancet Global Health
Commentary on Twitter
NEW—Eliminating preventable sight loss could bring economic benefits of US$411 billion a year, unlock human potential & accelerate global development. @LancetGH #GlobalEyeHealth Commission reports on action needed now to deliver key 👁️ health services. https://t.co/aLNmwKVENB pic.twitter.com/u69JFGL2BY
— The Lancet (@TheLancet) February 17, 2021
Global guideline for the diagnosis and management of rare mold infections
19 Feb, 2021 | 02:18h | UTC
Commentary on Twitter
🔥🔥🔥 Global Guideline for Rare Moulds. Endorsed by 55 scientific societies in the field.
All you need to know about Diagnosis and Treatment of Rare Mould infections: from Fusarium to Purpureocillium. @eurconfmedmycol @ISHAM_Mycology @ASMicrobiology
https://t.co/YJ3BX58osW pic.twitter.com/nrAGZl5ox4— Martin Hoenigl🇺🇦🇦🇹 (@martinhoenigl) February 16, 2021
WHO call to action: Vaccine equity declaration – We must accelerate vaccine equity for all health workers – Now
19 Feb, 2021 | 03:03h | UTCCall to Action: Vaccine Equity Declaration – World Health Organization
A single dose of the Pfizer–BioNTech vaccine is 92.6% effective in preventing Covid-19. Is delaying the second dose to get more people vaccinated an alternative?
19 Feb, 2021 | 02:59h | UTCSafety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine – New England Journal of Medicine
Commentary: Researchers urge delaying Pfizer vaccine’s second dose as first highly effective – Reuters
Covid-19: In vitro studies show Pfizer-BioNTech and Moderna vaccines produce fewer antibodies against South African variant
19 Feb, 2021 | 03:01h | UTCCommentaries: Expert reaction to two NEJM Correspondence articles on in vitro studies of the Pfizer-BioNTech and Moderna vaccines and different variants/mutations including mutations on the South Africa variant – Science Media Centre AND Lab studies suggest Pfizer, Moderna vaccines can protect against coronavirus variant – CNN AND Pfizer and Moderna vaccines have reduced effectiveness against South African variant, newly published studies show – The Washington Post AND Pfizer, Moderna vaccines less effective against South African COVID variant – MedicalXpress
Commentary on Twitter
New reports @NEJM today confirming some immune evasion of the B.1.351 variant (identified in South Africa) to both the mRNA vaccines, in vitro data @BioNTech_Group/@Pfizer and @moderna_tx. Less vaccine efficacy vs B.1.351 has been confirmed in clinical trials for 3 vaccines pic.twitter.com/2N7eKDllso
— Eric Topol (@EricTopol) February 17, 2021