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Studies: Secondary infections in patients with severe COVID-19

2 Mar, 2021 | 02:05h | UTC

Secondary Infections in Patients with Severe COVID-19 – NEJM Journal Watch

Study 1: Nosocomial infections associated to COVID-19 in the intensive care unit: clinical characteristics and outcome – Intensive Care Medicine

Study 2: COVID-19 increased the risk of ICU-acquired bloodstream infections: a case–cohort study from the multicentric OUTCOMEREA network – Intensive Care Medicine

Scaling up COVID-19 rapid antigen tests: promises and challenges

2 Mar, 2021 | 02:09h | UTC

Scaling up COVID-19 rapid antigen tests: promises and challenges – The Lancet Infectious Diseases

Review: Cardiovascular biomarkers in patients with COVID-19

2 Mar, 2021 | 02:07h | UTC

Cardiovascular biomarkers in patients with COVID-19 – European Heart Journal. Acute Cardiovascular Care

Commentary on Twitter

Cardiovascular #biomarkers in patients with #COVID19 – review article by @escardio Study Group on Biomarkers in Cardiology of the Acute Cardiovascular Care Association #ACVC_ESC https://t.co/9Mcx24fX8y #EHJACVC #cardiotwitter #medtwitter pic.twitter.com/y7kD2Oylrj

— European Society of Cardiology Journals (@ESC_Journals) March 1, 2021

Serious bradycardia and Remdesivir for COVID-19: a new safety concern

2 Mar, 2021 | 02:06h | UTC

Serious bradycardia and remdesivir for coronavirus 2019 (COVID-19): a new safety concerns – Clinical Microbiology and Infection

Commentary on Twitter

⛔A new safety concern⛔
New 🔥 post-marketing study @CMIJournal suggests that the use of remdesivir is significantly associated with an increased risk of reporting serious bradycardia compared with HCQ,LPV/RTV, tocilizumab or glucocorticoids #IDTwitter https://t.co/npLMchifEM

— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) February 27, 2021

Systematic Review: Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19

2 Mar, 2021 | 01:54h | UTC

Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19 – Cochrane Library

Summary: Can symptoms and medical examination accurately diagnose COVID-19? – Cochrane Library

We’ve updated our review on signs and symptoms for diagnosing Covid-19. Now includes evidence on loss of smell or taste #redflag ⁦ @deeksj⁩ ⁦@leeflang_m⁩ ⁦@devymaye⁩ ⁦@SabineDittrich⁩ ⁦@jacdinnes⁩ https://t.co/P4hBbuL0x9

— Ann Van den Bruel (@annvdbruel) February 24, 2021

Consensus Document: Venous thromboembolism prophylaxis in the trauma intensive care unit

2 Mar, 2021 | 01:52h | UTC

Venous thromboembolism prophylaxis in the trauma intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document – Trauma Surgery & Acute Care Open

Vaccinating the oldest against COVID-19 saves both the most lives and most years of life

2 Mar, 2021 | 02:04h | UTC

Vaccinating the oldest against COVID-19 saves both the most lives and most years of life – Proceedings of the National Academy of Sciences

Commentary: Vaccinating Oldest First for COVID Saves the Most Lives: Study – HealthDay

Commentary on Twitter

The policy of vaccinating the oldest vs covid-19:
Most lives saved and most years of life saved, the latter representing an unexpected extent of life expectancy gainhttps://t.co/KgLrl1j2xt @PNASNews by @jrgoldstein1 and colleagues pic.twitter.com/4MWZRa1i11

— Eric Topol (@EricTopol) February 25, 2021

Guideline: Treatment of methicillin-resistant Staphylococcus aureus (MRSA)

2 Mar, 2021 | 01:50h | UTC

Treatment of methicillin-resistant Staphylococcus aureus (MRSA): updated guidelines from the UK – JAC-Antimicrobial Resistance

Commentary on Twitter

We're delighted to publish the first update of UK #MRSA guidelines in more than a decade. Please share with your contacts & colleagues .

Treatment of methicillin-resistant Staphylococcus aureus (MRSA): updated guidelines from the UKhttps://t.co/3o3OVIdLuB #JACAMRNews #IDtwitter pic.twitter.com/GGlv1C1T1g

— JAC-AMR (@jac_amr) February 4, 2021

Who gets a COVID-19 vaccine and who pays? The need for economic analysis

2 Mar, 2021 | 02:02h | UTC

Who Gets a COVID-19 Vaccine and Who Pays? The Need for Economic Analysis – Center for Global Development

Commentary on Twitter

NEW from @CGDev and @idsihealth — experts look at the potential of Health Technology Assessment (HTA) on informing how much #COVID19 vaccine countries should buy, who should pay, and how vaccines can be most effectively delivered.

Read: https://t.co/KuMZSARSEF #GlobalHealth

— Center for Global Development (@CGDev) February 24, 2021

Fruit and Vegetable Intake and Mortality: Results From 2 Prospective Cohort Studies of US Men and Women and a Meta-Analysis of 26 Cohort Studies

2 Mar, 2021 | 01:44h | UTC

Fruit and Vegetable Intake and Mortality: Results From 2 Prospective Cohort Studies of US Men and Women and a Meta-Analysis of 26 Cohort Studies – Circulation

News release: The right ‘5-a-day’ mix is 2 fruit and 3 vegetable servings for longer life – American Heart Association

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

2 Mar, 2021 | 01:46h | UTC

Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge: a systematic review – JAC-Antimicrobial Resistance

Commentary on Twitter

“Direct oral challenge safe & effective for de-labelling patients at low risk for true allergy. Important for optimizing patient care and tackling #AMR” https://t.co/S3VL8JXyFJ #JACAMRNews #AMR #AMS @SAPGAbx @lac_cooper @jenny_harbour @raseaton66 @jacquisneddons pic.twitter.com/SwE1yyVr8d

— JAC-AMR (@jac_amr) February 23, 2021

RCT: Similar outcomes with intermittent vs. continuous pulse oximetry in hospitalized infants with stabilized bronchiolitis

2 Mar, 2021 | 01:42h | UTC

Intermittent vs Continuous Pulse Oximetry in Hospitalized Infants With Stabilized Bronchiolitis: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)

Editorial: Should We Prioritize Deimplementation of Continuous Pulse Oximetry in Bronchiolitis Care?

M-A: Glue vs. mechanical mesh fixation in laparoscopic inguinal hernia repair

2 Mar, 2021 | 01:29h | UTC

Glue versus mechanical mesh fixation in laparoscopic inguinal hernia repair: meta-analysis and trial sequential analysis of randomized clinical trials – British Journal of Surgery

Cohort study: Recovery of consciousness and functional outcome in moderate and severe traumatic brain injury

2 Mar, 2021 | 01:34h | UTC

Recovery of Consciousness and Functional Outcome in Moderate and Severe Traumatic Brain Injury – JAMA Neurology (free for a limited period)

Editorial: Holding Out Hope After Traumatic Brain Injury (free for a limited period)

Commentary on Twitter

In this study in @JAMANeuro:
most individuals who became comatose after moderate/severe traumatic brain injury recovered consciousness and ~50% regained functional independence, cautioning early decisions to withdraw/withhold treatment in these patients. https://t.co/jIz38AwCXO

— Saleh Almenawer, MD (@SalehAlmenawer) March 1, 2021

Cohort study: Association between preterm-birth phenotypes and differential morbidity, growth, and neurodevelopment at age 2 years

2 Mar, 2021 | 01:41h | UTC

Association Between Preterm-Birth Phenotypes and Differential Morbidity, Growth, and Neurodevelopment at Age 2 Years: Results From the INTERBIO-21st Newborn Study – JAMA Pediatrics

Teleneurology-enabled determination of death by neurologic criteria after cardiac arrest or severe neurologic injury

2 Mar, 2021 | 01:32h | UTC

Teleneurology-Enabled Determination of Death by Neurologic Criteria After Cardiac Arrest or Severe Neurologic Injury – Neurology (link to abstract – $ for full-text)

RCT: Prescribed light exercise vs. standard management for emergency department patients with acute mild traumatic brain injury

2 Mar, 2021 | 01:30h | UTC

A randomized trial comparing prescribed light exercise to standard management for emergency department patients with acute mild traumatic brain injury – Academic Emergency Medicine (link to abstract – $ for full-text)

Commentary: Exercise After Concussion in Adults? – Journal Feed

Laparoscopic Roux-en-Y gastric bypass vs. laparoscopic sleeve gastrectomy: 5-year outcomes of merged data from two randomized clinical trials

2 Mar, 2021 | 01:27h | UTC

Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: 5-year outcomes of merged data from two randomized clinical trials (SLEEVEPASS and SM-BOSS) – British Journal of Surgery

Visual abstract: Merged SLEEVEPASS and SM-BOSS trials

M-A: Umbilical cord management at term and late preterm birth

2 Mar, 2021 | 01:25h | UTC

Umbilical Cord Management at Term and Late Preterm Birth: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)

To beta-amyloid or not to beta-amyloid? An innovative meta-analysis offers new insight into Alzheimer’s drugs

2 Mar, 2021 | 01:18h | UTC

To beta-amyloid or not to beta-amyloid? An innovative meta-analysis offers new insight into Alzheimer’s drugs – UCSF Department of Epidemiology & Biostatistics

Original study: Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis – The BMJ

Commentary on Twitter

https://twitter.com/artwalaszek/status/1365098101845987328

Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis

2 Mar, 2021 | 01:24h | UTC

Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary on Twitter

The tubulin polymerization and Src kinase inhibitor tirbanibulin was superior to placebo ointment in clearing actinic keratoses on the face and scalp at 2 months. As is typical of the disorder, lesions recurred in 47% of patients at 1 year.

— NEJM (@NEJM) February 17, 2021