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RCT: Effect of ventral vs. dorsal spinal surgery on patient-reported physical functioning in patients with cervical spondylotic myelopathy

10 Mar, 2021 | 08:26h | UTC

Effect of Ventral vs Dorsal Spinal Surgery on Patient-Reported Physical Functioning in Patients With Cervical Spondylotic Myelopathy: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: First-of-its kind study compares two surgeries head-to-head for common neck condition – Beth Israel Lahey Health

 


Cohort study: Hypertensive disorders of pregnancy linked to subsequent risk of premature mortality

10 Mar, 2021 | 08:24h | UTC

Hypertensive Disorders of Pregnancy and Subsequent Risk of Premature Mortality – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Do Hypertension Disorders of Pregnancy Increase Risk of Premature Maternal Mortality? – American College of Cardiology AND Hypertension disorders of pregnancy increase risk of premature maternal mortality – American College of Cardiology

 


Position Statement: The Role of Pharmacogenomics in Contemporary Cardiovascular Therapy

11 Mar, 2021 | 07:53h | UTC

The Role of Pharmacogenomics in Contemporary Cardiovascular Therapy: A position statement from the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy – European Heart Journal – Cardiovascular Pharmacotherapy

 


RCT: Secondary cytoreduction followed by chemotherapy vs. chemotherapy alone in platinum-sensitive relapsed ovarian cancer

10 Mar, 2021 | 08:18h | UTC

Secondary cytoreduction followed by chemotherapy versus chemotherapy alone in platinum-sensitive relapsed ovarian cancer (SOC-1): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


WHO Report | Devastatingly pervasive: 1 in 3 women globally experience violence

10 Mar, 2021 | 08:21h | UTC

Devastatingly pervasive: 1 in 3 women globally experience violence – World Health Organization

Commentary: Violence Against Women Is “Unequivocally Pervasive”, Reveals Largest WHO Study Ever – Health Policy Watch

 


Global, regional, and national mortality trends in youth aged 15–24 years between 1990 and 2019: a systematic analysis

10 Mar, 2021 | 08:22h | UTC

Global, regional, and national mortality trends in youth aged 15–24 years between 1990 and 2019: a systematic analysis – The Lancet Global Health

Invited commentary: The pressing need for better statistics on youth mortality – The Lancet Global Health

 

https://twitter.com/BrunoMasquelier/status/1366707073715691523

 


[Press release – not published yet] Monoclonal antibodies reduced hospitalizations and death in Phase 3 trial for early COVID-19

11 Mar, 2021 | 08:41h | UTC

Press release: Lilly’s bamlanivimab and etesevimab together reduced hospitalizations and death in Phase 3 trial for early COVID-19

Commentary: Eli Lilly’s combo therapy for COVID-19 cuts serious illness and death in large study – Reuters

 


Death rate 64% higher with B117 COVID variant, study finds

11 Mar, 2021 | 08:38h | UTC

Death rate 64% higher with B117 COVID variant, study finds – CIDRAP

News release: Variant B.1.1.7 of COVID-19 associated with a significantly higher mortality rate, research shows – University of Bristol

Original Study: Risk of mortality in patients infected with SARS-CoV-2 variant of concern 202012/1: matched cohort study – The BMJ

 


Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

11 Mar, 2021 | 08:35h | UTC

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk – Association of Anaesthetists of Great Britain and Ireland

Original study: Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study – Anaesthesia

 

Commentary on Twitter

 


[Preprint] RECOVERY trial: Convalescent plasma does not improve outcomes in patients admitted to hospital with COVID-19

11 Mar, 2021 | 08:43h | UTC

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial – medRxiv

 

Commentary on Twitter (thread – click for more)

 


State of the Art Review | Severe covid-19 pneumonia: pathogenesis and clinical management

11 Mar, 2021 | 08:37h | UTC

Severe covid-19 pneumonia: pathogenesis and clinical management – The BMJ

 


Clinical Decisions | Doctor, How Long Should I Isolate?

11 Mar, 2021 | 08:21h | UTC

Doctor, How Long Should I Isolate? – New England Journal of Medicine

 


Study: Children and young people remain at low risk of COVID-19 mortality

11 Mar, 2021 | 08:28h | UTC

Children and young people remain at low risk of COVID-19 mortality – The Lancet Child and Adolescent Health

 


Attributes and predictors of long COVID

11 Mar, 2021 | 08:25h | UTC

Attributes and predictors of long COVID – Nature

 

Commentary on Twitter

https://twitter.com/ASPphysician/status/1369617507405946881

 


Audio Interview: The implications of changes in the structural biology of SARS-CoV-2

11 Mar, 2021 | 08:20h | UTC

Audio Interview: The Implications of Changes in the Structural Biology of SARS-CoV-2 – New England Journal of Medicine

 


More data suggesting a single dose of SARS-CoV-2 mRNA vaccine may be enough in seropositive individuals

11 Mar, 2021 | 08:18h | UTC

Antibody Responses in Seropositive Persons after a Single Dose of SARS-CoV-2 mRNA Vaccine – New England Journal of Medicine

Commentary: Second shot of COVID-19 vaccine may not be necessary in previously infected individuals: study – The Mount Sinai Hospital

Related: Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection (studies and commentary) AND Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2 – JAMA

 


RCT: Early surgical reconstruction vs. rehabilitation with elective delayed reconstruction for patients with anterior cruciate ligament rupture

10 Mar, 2021 | 08:17h | UTC

Early surgical reconstruction versus rehabilitation with elective delayed reconstruction for patients with anterior cruciate ligament rupture: COMPARE randomised controlled trial – The BMJ

 


Opinion | Amplified Pain Syndrome—An Insupportable Assumption

10 Mar, 2021 | 08:13h | UTC

Amplified Pain Syndrome—An Insupportable Assumption – JAMA Pediatrics

 


Guideline: To buy or not to buy—evaluating commercial AI solutions in radiology

10 Mar, 2021 | 08:15h | UTC

To buy or not to buy—evaluating commercial AI solutions in radiology (the ECLAIR guidelines) – European Radiology

Commentary: Top 10 questions to ask when buying radiology AI software – AuntMinnie

 


Review: Autoimmune enteropathy and its associated syndromes

10 Mar, 2021 | 08:10h | UTC

A Review of Autoimmune Enteropathy and Its Associated Syndromes – Digestive Diseases and Sciences

 


Practice Guidelines for Fecal Incontinence

10 Mar, 2021 | 08:11h | UTC

Japanese Practice Guidelines for Fecal Incontinence – Journal of the Anus, Rectum and Colon

Part 1: Definition, Epidemiology, Etiology, Pathophysiology and Causes, Risk Factors, Clinical Evaluations, and Symptomatic Scores and QoL Questionnaire for Clinical Evaluations

Part 2: Examination and Conservative Treatment for Fecal Incontinence

Part 3: Surgical Treatment for Fecal Incontinence, Fecal Incontinence in a Special Conditions

 


Clinical Update: Diagnosis and Treatment of Nonscarring Hair Loss in Primary Care in 2021

10 Mar, 2021 | 08:14h | UTC

Diagnosis and Treatment of Nonscarring Hair Loss in Primary Care in 2021 – JAMA (free for a limited period)

 


M-A: Serological evidence of human infection with SARS-CoV-2

10 Mar, 2021 | 08:42h | UTC

Serological evidence of human infection with SARS-CoV-2: a systematic review and meta-analysis – The Lancet Global Health

Invited Commentary: COVID-19 serosurveys for public health decision making – The Lancet Global Health

 

Commentary on Twitter (thread – click for more)

 


Lab study shows Pfizer/BioNTech COVID-19 vaccine can also neutralize B.1.351, P1 and B.1.1.7 variants

10 Mar, 2021 | 08:43h | UTC

Neutralizing Activity of BNT162b2-Elicited Serum – New England Journal of Medicine

Commentaries: Expert reaction to NEJM correspondence paper looking at the neutralising activity of the Pfizer-BioNTech vaccine against SARS-CoV-2 variants in the lab – Science Media Centre AND Pfizer/BioNTech COVID-19 vaccine neutralizes Brazil variant in lab study – Reuters

 


Study: Home testing for COVID-19 could prevent infections and reduce deaths at justifiable cost

10 Mar, 2021 | 08:40h | UTC

News release: Home testing for COVID-19 could prevent infections and reduce deaths at justifiable cost – Yale University

Original study: Clinical and Economic Effects of Widespread Rapid Testing to Decrease SARS-CoV-2 Transmission – Annals of Internal Medicine

 

Commentary on Twitter

 


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