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Meta-analysis of observational studies suggests better long-term oncologic outcomes with propofol-based total intravenous anesthesia compared to any volatile anesthesia

14 Mar, 2021 | 19:59h | UTC

Anesthesia and Long-term Oncological Outcomes: A Systematic Review and Meta-analysis – Anesthesia & Analgesia

 

Commentary on Twitter

 


Hearing loss prevalence and years lived with disability, 1990–2019: findings from the Global Burden of Disease Study 2019

12 Mar, 2021 | 08:16h | UTC

Hearing loss prevalence and years lived with disability, 1990–2019: findings from the Global Burden of Disease Study 2019 – The Lancet

Commentary: Addressing the global burden of hearing loss – The Lancet

Related: WHO Report: 1 in 4 people projected to have hearing problems by 2050

 

Commentary on Twitter

https://twitter.com/IHME_UW/status/1370167273407705089

 


Study shows increased risk of all-cause mortality in STEMI patients without standard modifiable risk factors

12 Mar, 2021 | 08:13h | UTC

Mortality in STEMI patients without standard modifiable risk factors: a sex-disaggregated analysis of SWEDEHEART registry data – The Lancet

 

Commentary on Twitter

 


Drug dosing in the critically ill obese patient: a focus on medications for hemodynamic support and prophylaxis

12 Mar, 2021 | 08:08h | UTC

Drug dosing in the critically ill obese patient: a focus on medications for hemodynamic support and prophylaxis – Critical Care

 


M-A: Angiographic Patency of Coronary Artery Bypass Conduits

12 Mar, 2021 | 08:10h | UTC

Angiographic Patency of Coronary Artery Bypass Conduits: A Network Meta‐Analysis of Randomized Trials – Journal of the American Heart Association

 


Pragmatic RCT: No difference in outcomes from different gestational diabetes screening methods

11 Mar, 2021 | 08:12h | UTC

A Pragmatic, Randomized Clinical Trial of Gestational Diabetes Screening – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: One-Step Screening for Gestational Diabetes Increases Diagnoses — But Doesn’t Improve Outcomes – NEJM Journal Watch AND How Do Screening Methods for Gestational Diabetes Compare? – AJMC AND Different gestational diabetes screening methods cause no difference for complications – 2 Minute Medicine

 


Consensus Statement: Preoperative management of endocrine, hormonal, and urologic medications

11 Mar, 2021 | 08:04h | UTC

Preoperative Management of Endocrine, Hormonal, and Urologic Medications: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement – Mayo Clinic Proceedings

 


M-A: Early tracheostomy may lower the rates of ventilator-associated pneumonia and ventilator duration in critically ill patients

12 Mar, 2021 | 08:09h | UTC

Association of Early vs Late Tracheostomy Placement With Pneumonia and Ventilator Days in Critically Ill Patients: A Meta-analysis – JAMA Otolaryngology-Head & Neck Surgery

Author interview: Early vs Late Tracheotomy for Pneumonia and Ventilator Days

 

 


AHA Scientific Statement | Opioid-Associated Out-of-Hospital Cardiac Arrest: Distinctive Clinical Features and Implications for Health Care and Public Responses

11 Mar, 2021 | 08:07h | UTC

Opioid-Associated Out-of-Hospital Cardiac Arrest: Distinctive Clinical Features and Implications for Health Care and Public Responses: A Scientific Statement From the American Heart Association – Circulation

 


[Press release – not published yet] Novavax reports 96% efficacy against original strain of COVID-19, 86% efficacy against B.1.1.7 variant, and 55% efficacy against B1.351 variant

12 Mar, 2021 | 08:33h | UTC

Press release: Novavax Confirms High Levels of Efficacy Against Original and Variant COVID-19 Strains in United Kingdom and South Africa Trials

Commentaries: Novavax Reports Its COVID-19 Vaccine is 96% Efficacious, Based on Phase 3 Trial Results – TIME AND Novavax Says Vaccine Is 96% Effective At Preventing Original Covid-19 Virus – Forbes

 

Commentary on Twitter

https://twitter.com/m_scribe/status/1370126020121083913

 


ERS Guideline: Management of hospitalized adults with COVID-19

12 Mar, 2021 | 08:36h | UTC

Management of hospitalised adults with coronavirus disease-19 (COVID-19): A European Respiratory Society living guideline – European Respiratory Journal

 


NCCN Best Practices Guidance: Management of COVID-19 Infection in Patients with Cancer

12 Mar, 2021 | 08:31h | UTC

NCCN Best Practices Guidance: Management of COVID-19 Infection in Patients with Cancer – National Comprehensive Cancer Network

News release: NCCN Provides New COVID-19 Treatment Advice; Updates Vaccine Guidance for Cancer Patients – National Comprehensive Cancer Network

 


COVID-19 and liver disease: mechanistic and clinical perspectives

12 Mar, 2021 | 08:29h | UTC

COVID-19 and liver disease: mechanistic and clinical perspectives – Nature Reviews Gastroenterology & Hepatology

 


Covid-19: European countries suspend use of Oxford-AstraZeneca vaccine after reports of blood clots

12 Mar, 2021 | 08:32h | UTC

Covid-19: European countries suspend use of Oxford-AstraZeneca vaccine after reports of blood clots – The BMJ

See also: More European nations pause AstraZeneca vaccine use as blood clot reports investigated – CNN AND Denmark, Norway and Iceland suspend AstraZeneca COVID shots after blood clot reports – Reuters

 

Commentary on Twitter

 


Update to living systematic review on covid-19 in pregnancy

12 Mar, 2021 | 08:28h | UTC

Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis – The BMJ

News release: Update to living systematic review on covid-19 in pregnancy – The BMJ

 


Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

12 Mar, 2021 | 08:23h | UTC

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies – Nature

 


Perspective | Long Covid isn’t as unique as we thought

12 Mar, 2021 | 08:27h | UTC

Long Covid isn’t as unique as we thought – Vox

 


Perspective | Immunity to SARS-CoV-2 variants of concern

12 Mar, 2021 | 08:24h | UTC

Immunity to SARS-CoV-2 variants of concern – Science

 

Commentary on Twitter

https://twitter.com/EricTopol/status/1370094431668375552

 


Managing Patients with Failing Kidney Allograft: Many Questions Remain

12 Mar, 2021 | 08:06h | UTC

Managing Patients with Failing Kidney Allograft: Many Questions Remain – Clinical Journal of the American Society of Nephrology

 


M-A: Sequential combination of pharmacotherapy and psychotherapy in major depressive disorder

11 Mar, 2021 | 08:00h | UTC

Sequential Combination of Pharmacotherapy and Psychotherapy in Major Depressive Disorder: A Systematic Review and Meta-analysis – JAMA Psychiatry

Commentary: How To Prevent A Relapse Of Clinical Depression – Forbes

 


CDC Interim Recommendations for Fully Vaccinated People: An Important First Step

12 Mar, 2021 | 08:22h | UTC

CDC Interim Recommendations for Fully Vaccinated People: An Important First Step – JAMA

Original Guidance and Commentaries: New CDC Guideline for fully vaccinated individuals says people can get together indoors without masks. Precautions should continue in public.

 


M-A: Little benefit from antidepressants for low back pain

11 Mar, 2021 | 08:02h | UTC

Efficacy, acceptability, and safety of antidepressants for low back pain: a systematic review and meta-analysis – Systematic Reviews

Commentary: Antidepressants provide no important benefits for managing low back pain – News Medical

Related meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis (study and commentaries)

 


Comparison of palliative care delivery in the last year of life between adults with terminal noncancer illness or cancer

11 Mar, 2021 | 07:55h | UTC

Comparison of Palliative Care Delivery in the Last Year of Life Between Adults With Terminal Noncancer Illness or Cancer – JAMA Network Open

Commentary: People with dementia receive fewer palliative referrals than those with cancer: study – McNight’s

 

Commentary on Twitter

 


Cohort study: Association of Ibuprofen prescription with acute kidney injury among hospitalized children

11 Mar, 2021 | 07:57h | UTC

Association of Ibuprofen Prescription With Acute Kidney Injury Among Hospitalized Children in China – JAMA Network Open

 

Commentary on Twitter

 


USPSTF Statement: begin screening for lung cancer at age 50 years instead of 55 years for patients at risk

10 Mar, 2021 | 08:28h | UTC

Recommendation Statement: Screening for Lung Cancer – US Preventive Services Task Force

Editorials: Broadened Eligibility for Lung Cancer Screening: Challenges and Uncertainty for Implementation and Equity – JAMA AND Expanded Access to Lung Cancer Screening—Implementing Wisely to Optimize Health – JAMA Network Open AND New USPSTF Guidelines for Lung Cancer Screening: Better but Not Enough – JAMA Surgery AND The 2021 US Preventive Services Task Force Recommendation on Lung Cancer Screening: The More Things Stay the Same… – JAMA Oncology

 


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