Archives
RCT: Oxford/AstraZeneca vaccine does not protect against mild-to-moderate Covid-19 due to the B.1.351 variant
17 Mar, 2021 | 03:01h | UTCCommentaries: AstraZeneca vaccine doesn’t prevent B1351 COVID in early trial – CIDRAP AND Oxford/AstraZeneca Fails to Prevent Mild to Moderate Covid-19 From B.1.351 (“South Africa”) Variant – Brief19
FDA: Why you should not use Ivermectin to treat or prevent COVID-19
17 Mar, 2021 | 02:51h | UTCWhy You Should Not Use Ivermectin to Treat or Prevent COVID-19 – U.S. Food & Drug Administration
Commentary: FDA Rejects Ivermectin, Despite Growing Interest In Some Corners Of The Internet – Brief19
Related: RCT: Ivermectin does not improve time to resolution of symptoms among adults with mild COVID-19
COVID‐19 and its cardiovascular effects: a systematic review of prevalence studies
17 Mar, 2021 | 02:52h | UTC
Commentary on Twitter
How common are pre‐existing heart & blood vessel problems in #COVID19? What are most common complications affecting heart & blood vessels in #COVID19? @CochraneHeart review of prevalence studies: https://t.co/rDqz2GyrpH
— The Cochrane Library (@CochraneLibrary) March 12, 2021
Imaging review of peripheral nerve injuries in patients with COVID-19
17 Mar, 2021 | 02:48h | UTCImaging Review of Peripheral Nerve Injuries in Patients with COVID-19 – Radiology
‘Then the world caved in’: 11 experts describe the day they realized Covid-19 was here to stay
17 Mar, 2021 | 02:49h | UTC
COVID antibody treatments show promise for preventing severe disease
17 Mar, 2021 | 02:46h | UTCCOVID antibody treatments show promise for preventing severe disease – Nature
Consensus Statement on Analgo-sedation in Neurocritical Care and Review of Literature
17 Mar, 2021 | 02:09h | UTC
Meta-analysis of randomized trials bring into question the belief that betablockers cause depression
16 Mar, 2021 | 01:47h | UTCDo β-Blockers Cause Depression? Systematic Review and Meta-Analysis of Psychiatric Adverse Events During β-Blocker Therapy – Hypertension (link to abstract – $ for full-text)
News release: Beta-blockers not likely to cause depression yet may contribute to sleep disturbances – American Heart Association
Commentary: Beta blockers not associated with risk of depression – Charité – Universitätsmedizin Berlin
Central nervous system–active polypharmacy common among older adults with dementia in the US
16 Mar, 2021 | 01:45h | UTCPrevalence of Central Nervous System–Active Polypharmacy Among Older Adults With Dementia in the US – JAMA (free for a limited period)
Commentaries: CNS-Active Polypharmacy Examined in Seniors With Dementia – HealthDay AND A Trio That Could Spell Trouble: Many with Dementia Take Risky Combinations of Medicines – Michigan Medicine – University of Michigan AND Older Adults With Dementia at Risk From Taking Multiple Psychotropics, Study Suggests – Psychiatric News Alert
Commentary on Twitter
In this cross-sectional study of Medicare claims, 14% of older adults with dementia filled prescriptions consistent with CNS-active polypharmacy in 2018 (eg 3+ antidepressants, antipsychotics, BNZ, Z-drugs, or opioids) https://t.co/85BmGgeYil @dtmaust @umichmedicine @PennMedicine
— JAMA (@JAMA_current) March 9, 2021
RCT: No benefit from probiotic therapy in critical illness
16 Mar, 2021 | 01:30h | UTC
Commentary on Twitter
Early & sustained untargeted administration of probiotics to adults admitted to #ICU safe, but not associated with improved outcomes. ROCIT, restoration of gut microflora in critical illness, trial visual abstract full text open access #FOAMcc on @yourICM https://t.co/mP4bkHpqSs pic.twitter.com/bu3EGUyDCm
— Intensive Care Medicine (@yourICM) March 15, 2021
Platelet tests pre-CABG may safely shorten washout waits, cut costs
16 Mar, 2021 | 01:44h | UTCPlatelet Tests Pre-CABG May Safely Shorten Washout Waits, Cut Costs – TCTMD
Special Issue: The importance of women’s health in peri‐operative care
16 Mar, 2021 | 01:42h | UTCSpecial Issue: The importance of women’s health in peri‐operative care – Anaesthesia
5 ways to spot if someone is trying to mislead you when it comes to science
16 Mar, 2021 | 01:41h | UTC5 ways to spot if someone is trying to mislead you when it comes to science – The Conversation
Commentary on Twitter
Solid list! "5 ways to spot if someone is trying to mislead you when it comes to science" https://t.co/AnFZtWuUBc via @ConversationEDU
1. The ‘us versus them’ narrative
2. ‘I’m not a scientist, but…’
3. Ref to ‘science not being settled’
4. Overly simplistic
5. Cherry-picking— Timothy Caulfield (@CaulfieldTim) March 14, 2021
RCT: Little benefit from osteopathic manipulative treatment on activity limitations in patients with nonspecific subacute and chronic low back pain
16 Mar, 2021 | 01:39h | UTCEffect of Osteopathic Manipulative Treatment vs Sham Treatment on Activity Limitations in Patients With Nonspecific Subacute and Chronic Low Back Pain: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Visual abstract: Effect of Osteopathic Manipulative Treatment vs Sham Treatment on Activity Limitations in Patients With Nonspecific Subacute and Chronic Low Back Pain
M-A: Assessment of postnatal corticosteroids for the prevention of bronchopulmonary dysplasia in preterm neonates
16 Mar, 2021 | 01:38h | UTCAssessment of Postnatal Corticosteroids for the Prevention of Bronchopulmonary Dysplasia in Preterm Neonates: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (free for a limited period)
Editorial: The Swinging Pendulum of Postnatal Corticosteroid Use (free for a limited period)
Update on the safety of COVID-19 Vaccine AstraZeneca
16 Mar, 2021 | 02:35h | UTCUpdate on the safety of COVID-19 Vaccine AstraZeneca
Related: Countries should continue AstraZeneca rollout: WHO – MedicalXpress AND Expert reaction to news that Germany has halted vaccinations with the Oxford-AstraZeneca COVID-19 vaccine – Science Media Centre AND AstraZeneca finds no evidence of increased blood clot risk from vaccine – Reuters AND Data suggest no increased risk of blood clots from the AstraZeneca vaccine. Australia shouldn’t pause its rollout – The Conversation
Commentary on Twitter
As of March 8th, Around 17 million people in the EU & UK received the vaccine , there have been 15 events of DVT & 22 events of pulmonary embolism reported among those given the vaccine,This is much lower than would be expected to occur naturally in a general population
Please RT https://t.co/tnn4brxwpp— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) March 14, 2021
B.1.1.7 variant linked to 55% higher mortality compared to other strains of SARS-CoV-2
16 Mar, 2021 | 02:32h | UTCOriginal study: Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7 – Nature
Related: Death rate 64% higher with B117 COVID variant, study finds (study and commentary)
Commentary on Twitter (thread – Click for more)
https://mobile.twitter.com/_nickdavies/status/1371441682089132032
Antibody response after SARS-CoV-2 infection and implications for immunity: A rapid living review
16 Mar, 2021 | 02:30h | UTC
ACP Practice Points: What is the antibody response and role in conferring natural immunity after SARS-CoV-2 infection?
16 Mar, 2021 | 02:29h | UTC
Assessing risk for healthcare workers during the covid-19 pandemic
16 Mar, 2021 | 02:25h | UTCAssessing risk for healthcare workers during the covid-19 pandemic – The BMJ
Commentary on Twitter
NEW #BMJEducation article discusses how employers can assess risks for healthcare workers during the #COVID19 pandemic. @Azeem_Majeed @kamleshkhunti @RaoMala @CNagpaul Amanda Griffiths https://t.co/YbpZhrLsmz pic.twitter.com/e3TU56EQqH
— The BMJ (@bmj_latest) March 15, 2021
The first 12 months of COVID-19: a timeline of immunological insights
16 Mar, 2021 | 02:22h | UTCThe first 12 months of COVID-19: a timeline of immunological insights – Nature Reviews Immunology
Commentary on Twitter
We've learned a lot on the immune response and multiple discoveries throughout the covid-19 pandemic and I can't imagine it could be better summarized than by this new @NatRevImmunol paper or these authors @CyrilPedia @florian_krammer @VirusesImmunity https://t.co/6SOSP5URFf pic.twitter.com/nOCTOzmzBY
— Eric Topol (@EricTopol) March 15, 2021
Nature Series: Preparing for the next pandemic
16 Mar, 2021 | 02:19h | UTCPreparing for the next pandemic – Nature Medicine
Commentary on Twitter
Preparing for the next pandemic. A terrific collection of more than a dozen papers out today @NatureMedicine https://t.co/oQWy6q3qYs by so many of the people and labs who have guided us through the current one, including @devisridhar @gmleunghku @Baric_Lab
— Eric Topol (@EricTopol) March 15, 2021
Cartoons that explain how the COVID vaccines work
16 Mar, 2021 | 02:13h | UTCCartoons that explain how the COVID vaccines work – KevinMD
More than half of COVID-19 patients report depressive symptoms months later, study finds
16 Mar, 2021 | 02:11h | UTCOriginal study: Association of Acute Symptoms of COVID-19 and Symptoms of Depression in Adults – JAMA Network Open
Commentary on Twitter
Survey study finds 52% of individuals with prior #COVID19 met criteria for moderate or greater symptoms of depression; more likely in younger, male, and those with more severe #COVID19 @royperlis @HarvardMed @Ognyanova @RutgersU @NorthwesternU @dellavolpe https://t.co/4krNvFb29T
— JAMA Network Open (@JAMANetworkOpen) March 13, 2021
Perspective | Prioritizing peritoneal catheter placement during the COVID-19 pandemic
16 Mar, 2021 | 02:16h | UTC
Commentary on Twitter
Individuals receiving dialysis are at high risk of COVID-19 infection, but promoting peritoneal dialysis is one potential way to substantially lower the risk. This perspective outlines how COVID-19 has changed the importance of timely PD catheter insertion https://t.co/Sy2pUShfNU pic.twitter.com/GueiogpO5b
— CJASN (@CJASN) March 12, 2021