RCT: No benefit from probiotic therapy in critical illness

Early and sustained Lactobacillus plantarum probiotic therapy in critical illness: the randomised, placebo-controlled, restoration of gut microflora in critical illness trial (ROCIT) – Intensive Care Medicine

Commentary on Twitter

Early & sustained untargeted administration of probiotics to adults admitted to #ICU safe, but not associated with improved outcomes. ROCIT, restoration of gut microflora in critical illness, trial visual abstract full text open access #FOAMcc on @yourICM https://t.co/mP4bkHpqSs pic.twitter.com/bu3EGUyDCm

— Intens Care Med (@yourICM) March 15, 2021