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The Lancet Series: Interstitial Lung Disease 2021.

7 Sep, 2021 | 21:37h | UTC

Homepage: Interstitial Lung Disease 2021 (free registration required for all articles)

Disease pathology in fibrotic interstitial lung disease: is it all about usual interstitial pneumonia?

Early diagnosis of fibrotic interstitial lung disease: challenges and opportunities

Treatment of fibrotic interstitial lung disease: current approaches and future directions

Interstitial lung diseases: quo vadis?

Moving beyond usual interstitial pneumonia to define progressive fibrotic interstitial lung disease

 

Commentary on Twitter (thread – click for more)

 


Isn’t it time to abandon ARDS? The COVID-19 lesson.

7 Sep, 2021 | 21:34h | UTC

Isn’t it time to abandon ARDS? The COVID-19 lesson – Critical Care

 

Commentary on Twitter

 


Extended intervals and extra doses of the AstraZeneca vaccine are associated with increased immunogenicity.

7 Sep, 2021 | 10:56h | UTC

Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002) – The Lancet

Invited commentary: Longer intervals and extra doses of ChAdOx1 nCoV-19 vaccine

 

Commentaries on Twitter

(thread – click for more)

(thread – click for more)

 


Opinion | Liquid biopsy: misplaced faith in early cancer detection?

7 Sep, 2021 | 21:30h | UTC

Liquid biopsy: misplaced faith in early cancer detection? – STAT

 

Commentary on Twitter

 


Defining pediatric metabolic (dysfunction)-associated fatty liver disease: an international expert consensus statement.

7 Sep, 2021 | 21:26h | UTC

Defining paediatric metabolic (dysfunction)-associated fatty liver disease: an international expert consensus statement – The Lancet Gastroenterology & Hepatology (free registration required)

 

Commentary on Twitter

 


Antibiotics use is linked to increased risk of subsequent colorectal cancer.

7 Sep, 2021 | 21:25h | UTC

Antibiotics Use and Subsequent Risk of Colorectal Cancer: A Swedish Nationwide Population-Based Study – JNCI: Journal of the National Cancer Institute

Commentaries:

Antibiotics linked to increased risk of colon cancer – Umea University

Study links antibiotics use and increased subsequent risk of colorectal cancer – MedicalResearch.com

 


[Preprint] Large cohort study in Brazil showed AstraZeneca vaccine had high overall effectiveness against severe disease to individuals up to 89 years of age. In comparison, CoronaVac had high overall effectiveness against severe disease in individuals up to 79 years.

7 Sep, 2021 | 10:54h | UTC

Influence of age on the effectiveness and duration of protection in Vaxzevria and CoronaVac vaccines – medRxiv

 


Annual Update in Intensive Care and Emergency Medicine 2021 – Covid articles.

7 Sep, 2021 | 10:50h | UTC

Secondary infections in critically ill patients with COVID-19

Tracheostomy for COVID-19: evolving best practice

See also: Non-Covid articles

 


Case series: COVID-19 mRNA vaccination leading to CNS inflammation.

7 Sep, 2021 | 10:49h | UTC

COVID-19 mRNA vaccination leading to CNS inflammation: a case series – Journal of Neurology

 


Opinion | Video: Immunity is the only way through a pandemic (w/Dr. Monica Gandhi).

7 Sep, 2021 | 10:45h | UTC

Immunity Is The Only Way Through A Pandemic (w/Dr. Monica Gandhi) – ZDoggMD

 


CDC report: Hospitalization rates for Covid-19 were 10 times higher among unvaccinated than among fully vaccinated adolescents.

7 Sep, 2021 | 10:52h | UTC

Hospitalizations Associated with COVID-19 Among Children and Adolescents — COVID-NET, 14 States, March 1, 2020–August 14, 2021 – CDC Morbidity and Mortality Weekly Report

Commentaries:

More kids hospitalized with Covid-19 in states with lower vaccination rates, CDC report finds – CNN

The hospitalization rate among teens who are unvaccinated is 10 times higher than teens who are vaccinated, new CDC data shows – Insider

Child COVID hospital cases up in low-vaccination states – CIDRAP

 

Commentary on Twitter

 


[Not published yet] Sinovac booster shot reverses drop in antibody activities against Delta-study.

7 Sep, 2021 | 10:47h | UTC

Sinovac booster shot reverses drop in antibody activities against Delta-study – Reuters

 

Commentary on Twitter

 


Medical, ethical, and legal aspects of end-of-life dilemmas in the intensive care unit.

7 Sep, 2021 | 10:37h | UTC

Medical, ethical, and legal aspects of end-of-life dilemmas in the intensive care unit – Cleveland Clinic Journal of Medicine

 


Cohort study: Serum markers of brain injury can predict good neurological outcome after out-of-hospital cardiac arrest.

7 Sep, 2021 | 10:41h | UTC

Serum markers of brain injury can predict good neurological outcome after out-of-hospital cardiac arrest – Intensive Care Medicine

 

Commentary on Twitter

 


Tube feeding for people with severe dementia: making decisions.

7 Sep, 2021 | 10:39h | UTC

Tube feeding for people with severe dementia: making decisions – Evidently Cochrane

Original article: Systematic review: Enteral tube feeding for people with severe dementia – “We found no evidence that tube feeding improves survival; improves quality of life; reduces pain; reduces mortality; decreases behavioural and psychological symptoms of dementia”.

 


Annual Update in Intensive Care and Emergency Medicine 2021 – Non-Covid articles.

7 Sep, 2021 | 10:43h | UTC

Advanced management of intermediate-high risk pulmonary embolism

Pathophysiology and clinical implications of the veno-arterial PCO2 gap

To prone or not to prone ARDS patients on ECMO

Management of acute metabolic acidosis in the ICU: sodium bicarbonate and renal replacement therapy

Acute kidney injury in ECMO patients

Monitoring and modifying brain oxygenation in patients at risk of hypoxic ischaemic brain injury after cardiac arrest

Measuring vitamin C in critically ill patients: clinical importance and practical difficulties—Is it time for a surrogate marker?

Still a place for aortic counterpulsation in cardiac surgery and patients with cardiogenic shock?

See also: Covid articles

 


ESPEN practical guideline: Clinical nutrition in chronic intestinal failure.

7 Sep, 2021 | 10:32h | UTC

ESPEN practical guideline: Clinical nutrition in chronic intestinal failure – Clinical Nutrition

 


Podcast: Febrile Infants (based on the new AAP Guideline).

7 Sep, 2021 | 10:31h | UTC

#33: Febrile Infants – When Babies Are Too Hot – The Cribsiders

Original guideline:

AAP Guideline: Evaluation and management of well-appearing febrile infants 8 to 60 days old.

Commentaries:

Landmark Febrile Neonate, Febrile Infant Guideline from the AAP – JournalFeed

Small Talk – Hot Off The Presses: The Latest AAP Guidelines for the Febrile Neonate – emDocs

Related:

M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.

Things We Do for No Reason: Lumbar Punctures in Low-Risk Febrile Infants with Bronchiolitis

[Abstract Only] Observational Study Suggests Testing for Meningitis May Not be Necessary for Febrile Well-Appearing Young Infants with Positive Urinalysis

Study: Clinical Prediction Rule to Identify Febrile Infants at Low Risk for Serious Bacterial Infections

Cohort Study: Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections

 


Care of the adult cancer patient at the end of life: ESMO Clinical Practice Guidelines.

7 Sep, 2021 | 10:34h | UTC

Care of the adult cancer patient at the end of life: ESMO Clinical Practice Guidelines – ESMO Open

 


More data showing increased risk of hospitalization with SARS-CoV-2 delta variant.

6 Sep, 2021 | 11:12h | UTC

Hospitalisation associated with SARS-CoV-2 delta variant in Denmark – The Lancet Infectious Diseases

Related study: Cohort study: Patients with Covid-19 infected with the Delta variant are twice as likely to need hospital admission or emergency care attendance.

 


Podcast: The Best of Liver Tests.

7 Sep, 2021 | 10:29h | UTC

#293 The Best of Liver Tests with Dr. Elliot Tapper – The Curbsiders

 


The resurgence of SARS-CoV-2 infection in a highly vaccinated health system workforce; vaccine effectiveness against infection was reduced from above 90% from March through June to 65% in July.

6 Sep, 2021 | 11:09h | UTC

Resurgence of SARS-CoV-2 Infection in a Highly Vaccinated Health System Workforce – New England Journal of Medicine

Related:

Another study shows Pfizer mRNA vaccine immunity is reduced over time.

Study shows AstraZeneca and Pfizer vaccines are effective against Delta variant, but both doses are needed.

 

Commentary on Twitter (thread – click for more)

 


RCT: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels.

6 Sep, 2021 | 11:11h | UTC

Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial – Nature Medicine

 

Commentary on Twitter

 


Large surveillance study finds severe adverse events after COVID-19 mRNA vaccination are rare.

6 Sep, 2021 | 11:02h | UTC

Surveillance for Adverse Events After COVID-19 mRNA Vaccination – JAMA

Editorial: Safety Surveillance of COVID-19 mRNA Vaccines Through the Vaccine Safety Datalink – JAMA

Commentaries:

mRNA COVID vaccines not tied to serious side effects – CIDRAP

Researchers find no serious health effects linked to mRNA COVID-19 vaccines – News Medical

 

Commentary on Twitter

 


Systematic review: evaluation of dietary patterns and all-cause mortality.

6 Sep, 2021 | 10:43h | UTC

Evaluation of Dietary Patterns and All-Cause Mortality: A Systematic Review – JAMA Network Open

 

Commentary on Twitter (thread – click for more)

 


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