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An FDA panel says only high-risk Americans and those 65+ should get covid boosters.

19 Sep, 2021 | 23:45h | UTC

An FDA Panel Says Only High-Risk Americans And Those 65+ Should Get COVID Boosters – NPR

See also:

FDA advisory panel recommends booster doses of Covid-19 vaccine only for older and high-risk Americans – STAT

5 reasons why FDA advisers did not recommend Covid-19 booster shots for everyone – CNN

Top doctors say not so fast to Biden’s boosters-for-all plan – Associated Press

Related:

An observational study in Israel suggests additional protection from a 3rd dose of the Pfizer vaccine in individuals 60 years of age or older.

Third shot: UK to offer COVID booster jabs to over 50s.

COVID-19 vaccine efficacy does not support boosters for general population, review concludes.

COVID vaccine effects wane over time but still prevent death and severe illness.

What’s the evidence for COVID-19 booster shots?

WHO appeals for countries to postpone COVID-19 vaccine boosters until 2022 to prioritize vaccinating the most at-risk people around the world who are yet to receive their first dose.

AstraZeneca bosses warn against rush for boosters – “giving the most vulnerable, who may not have built up a full immune response from the first two, a third, top-up dose is “sensible”. But any decision to give a third, booster jab “to large swathes of the population”, to extend their protection from the first two, must be based on clinical data”.

 

COVID vaccine immunity is waning — how much does that matter? – “As debates about booster shots heat up, what’s known about the duration of vaccine-based immunity is still evolving”.

19 Sep, 2021 | 23:40h | UTC

COVID vaccine immunity is waning — how much does that matter? – Nature

 

Opinion | Vaccinate the World before Starting COVID Booster Shots – “Fewer than 0.5 percent of vaccine doses have been distributed to people living in low-income countries”.

19 Sep, 2021 | 23:41h | UTC

Vaccinate the World before Starting COVID Booster Shots – Scientific American

Related: WHO appeals for countries to postpone COVID-19 vaccine boosters until 2022 to prioritize vaccinating the most at-risk people around the world who are yet to receive their first dose.

 

Review: Long COVID symptoms in children rarely persist beyond three months.

19 Sep, 2021 | 23:47h | UTC

News release: Long COVID symptoms in children rarely persist beyond three months –  Murdoch Children’s Research Institute

Original study: How Common Is Long COVID in Children and Adolescents? – The Pediatric Infectious Disease Journal

Commentary: Long Covid in children and adolescents is less common than previously feared – The Guardian

Related:

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Long COVID: the physical and mental health of children and non-hospitalized young people after SARS-CoV-2 infection – one in seven children may still have symptoms 15 weeks after infection.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Cohort study: Risk factors for long covid in previously hospitalized children.

M-A: More than 50 long-term effects of COVID-19.

 

Commentary on Twitter (thread – click for more)

 

Side effect patterns in a crossover trial of statin, placebo, and no treatment – This N-of-1 trial, now published in full, suggests the nocebo effect causes most of statins muscle adverse effects.

19 Sep, 2021 | 23:30h | UTC

Side Effect Patterns in a Crossover Trial of Statin, Placebo, and No Treatment – Journal of the American College of Cardiology

See also: #AHA20 – In patients who had discontinued statins because of side effects, a N-of-1 trial of a statin, placebo, or no treatment found that side effects often attributed to statins were the same for those taking a placebo

 

WHO/ILO: Almost 2 million people die from work-related causes each year.

19 Sep, 2021 | 23:39h | UTC

News release: WHO/ILO: Almost 2 million people die from work-related causes each year – World Health Organization

Report: WHO/ILO joint estimates of the work-related burden of disease and injury, 2000-2016: global monitoring report – World Health Organization

 

Commentary on Twitter

 

Non-alcoholic fatty liver disease: A patient guideline.

19 Sep, 2021 | 23:35h | UTC

Non-alcoholic fatty liver disease: A patient guideline – JHEP Reports

 

Commentary on Twitter

 

Large cohort study suggests routine replacement (every 96 hours) of peripheral intravenous catheters may reduce the risk of bloodstream infections compared to clinically indicated replacement.

19 Sep, 2021 | 23:34h | UTC

Comparison of Routine Replacement With Clinically Indicated Replacement of Peripheral Intravenous Catheters – JAMA Internal Medicine (free for a limited period)

Related Cochrane Review with different findings: Systematic Review: Clinically‐indicated vs. Routine Replacement of Peripheral Venous Catheters

 

Commentary on Twitter

 

Lamotrigine in the maintenance treatment of bipolar disorder.

19 Sep, 2021 | 23:25h | UTC

Lamotrigine in the maintenance treatment of bipolar disorder – Cochrane Library

Summary: Lamotrigine as a treatment for prevention of recurrence of bipolar disorder – Cochrane Library

 

Editorial: Brain health and its social determinants.

19 Sep, 2021 | 23:28h | UTC

Brain health and its social determinants – The Lancet

 

Commentary on Twitter

 

CDC Report: SARS-CoV-2 transmission to masked and unmasked close contacts of university students with COVID-19.

17 Sep, 2021 | 10:17h | UTC

SARS-CoV-2 Transmission to Masked and Unmasked Close Contacts of University Students with COVID-19 — St. Louis, Missouri, January–May 2021 – CDC Morbidity and Mortality Weekly Report

 

Commentary on Twitter

https://twitter.com/eliowa/status/1436017429927370758

 

Choosing Wisely: Five things clinicians and patients should question in rural medicine.

19 Sep, 2021 | 23:26h | UTC

Choosing Wisely Canada: Rural medicine list of recommendations – Canadian Journal of Rural Medicine

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

Roux‐en‐Y versus Billroth‐I reconstruction after distal gastrectomy for gastric cancer.

19 Sep, 2021 | 23:24h | UTC

Roux‐en‐Y versus Billroth‐I reconstruction after distal gastrectomy for gastric cancer – Cochrane Library

 

CDC Report: Using Wastewater Surveillance Data to Support the COVID-19 Response — United States, 2020–2021.

17 Sep, 2021 | 10:15h | UTC

Using Wastewater Surveillance Data to Support the COVID-19 Response — United States, 2020–2021 – CDC Morbidity and Mortality Weekly Report

Related:

Rapid, large-scale wastewater surveillance and automated reporting system enabled early detection of nearly 85% of COVID-19 cases on a University campus.

[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.

Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME

Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT

Sewage sleuths helped an Arizona town beat back Covid-19. For wastewater epidemiology, that’s just the start – STAT

The myriad ways sewage surveillance is helping fight COVID around the world – Nature

Testing sewage can give school districts, campuses and businesses a heads-up on the spread of COVID-19 – The Conversation

It’s time to begin a national wastewater testing program for Covid-19 – STAT

Coronavirus: Testing sewage an ‘easy win’ – BBC

Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – high sensitivity, but unable to distinguish new infectious cases from persistent convalescent shedding.

 

Commentary on Twitter

 

RCT: Rivaroxaban does not have an impact on disease progression and symptoms resolution in high-risk adults with mild COVID-19.

17 Sep, 2021 | 10:19h | UTC

Randomized study of rivaroxaban vs. placebo on disease progression and symptoms resolution in high-risk adults with mild COVID-19 – Clinical Infectious Diseases

 

Vaccine passports are coming. But are they ethical?

17 Sep, 2021 | 10:10h | UTC

Vaccine passports are coming. But are they ethical? – The Conversation

Related:

Infographic: Vaccine passports around the world.

WHO panel comes out against requiring vaccination proof for travel

Opinion | How to lose friends and alienate people? On the problems of vaccine passports (several texts on the subject)

 

How the Delta variant’s remarkable ability to replicate threw new twists into the Covid-19 pandemic.

17 Sep, 2021 | 10:09h | UTC

How the Delta variant’s remarkable ability to replicate threw new twists into the Covid-19 pandemic – STAT

 

Management of COVID-19 ICU-survivors in primary care: – a narrative review.

17 Sep, 2021 | 10:13h | UTC

Management of COVID-19 ICU-survivors in primary care: – a narrative review – BMC Family Practice

 

COVID-19 in gastroenterology: Where are we now? Current evidence on the impact of COVID-19 in gastroenterology.

17 Sep, 2021 | 10:11h | UTC

COVID-19 in gastroenterology: Where are we now? Current evidence on the impact of COVID-19 in gastroenterology – UEG Journal

 

As Covid Cases Rise, So Do Hospital-Related Infections.

17 Sep, 2021 | 10:08h | UTC

As Covid Cases Rise, So Do Hospital-Related Infections – Wired

 

WSES-AAST Guidelines: Anorectal Emergencies.

17 Sep, 2021 | 10:06h | UTC

Anorectal emergencies: WSES-AAST guidelines – World Journal of Emergency Surgery

 

Systematic Review: Interventional treatments for acute and chronic pain.

17 Sep, 2021 | 10:01h | UTC

Interventional Treatments for Acute and Chronic Pain: Systematic Review – Agency for Healthcare Research and Quality

Full report

Evidence summary

 

AAN Position Statement: Ethical Considerations in Dementia Diagnosis and Care.

17 Sep, 2021 | 10:04h | UTC

Ethical Considerations in Dementia Diagnosis and Care: AAN Position Statement – Neurology

 

Guideline: Diagnosis, evaluation, and management of ascites, spontaneous bacterial peritonitis and hepatorenal syndrome.

17 Sep, 2021 | 10:07h | UTC

Diagnosis, Evaluation, and Management of Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome: 2021 Practice Guidance by the American Association for the Study of Liver Diseases – Hepatology

 

RCT: The addition of telemedicine to improve standard care for medically complex children was associated with improved clinical outcomes and reduced costs.

17 Sep, 2021 | 10:00h | UTC

Telemedicine for Children With Medical Complexity: A Randomized Clinical Trial – Pediatrics

 

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